The synthesis of polymeric dual-functional antimicrobial surface based on poly(2-methyl-2-oxazoline)

There is a high interest in the development of antimicrobial coatings to fi ght bacterial infections.We present the development of dual-functional antimicrobial surface, in which a biopassive platform wasfunctionalized with bioactive compounds on the surface, using a graft copolymer system poly(L-lysine)-graftpoly(2-methyl-2-oxazoline)-quarternery ammonium compound (PLL-g-PMOXA-QAC). Alkyne functionalitywas introduced to the PMOXA chain at α-terminus by initiating the living cationic polymerization of 2-methyl-2-oxazoline with a propargylic-initiator. The reaction was terminated with carboxy derivative-terminator thatallows grafting of the polymeric chain from the β-terminus to poly(L-lysine) (PLL) backbone, resulting in graftcopolymer alkynyl PLL-g-PMOXA. The conjugation between alkynyl PLL-g-PMOXA and QAC was thenperformed using click reaction. The chemical structures of the polymers were characterized by MALDI-TOFspectrometry and NMR spectroscopy. The results demonstrate that we have successfully synthesized PLL-g-PMOXA-QAC copolymer with grafting density (number of lysine/number of PMOXA) of 0.33. The resultingPLL-g-PMOXA-QAC copolymer was then immobilized onto carboxylated tissue cultured polystyrene (TCPS)surface and exposed to bacteria solution to test its dual-functional properties. Preliminary live-and-deadbacteria study indicates dual-functionality of the PLL-g-PMOXA-QAC-coated surface

The preparation of dual-functional hydrogel as the surface coating of plastics in biomedical applications

Poly(2-ethyl-2-oxazoline) (PEOXA) is among polymers that have been reported to show anti-adhesive (bio-passive) behavior in numerous biomaterial applications. This work aimed to develop dual-functional hydrogel coatings, with PEOXA as hydrophilic polymer and benzophenone as cross-linker. PEOXA was partially hydrolyzed in acidic conditions to form PEOXA-m% EI that contains ethyleneimine (EI) groups. The EI groups were used as conjugation sites for incorporation of benzophenone (BP) molecules to PEOXA chains to form PEOXA-m% EIBP. Thin films of surface-attached polymer networks were generated from PEOXA-m% EIBP copolymers composed of PEOXA as platform and benzophenone as crosslinker units. The polymer became crosslinked through benzophenone units and forms a hydrogel as biopassive platform during irradiation with ultraviolet (UV) light. Laminin was incorporated into biopassive polymer network to allow for preparation of dual-functional hydrogel. NMR spectra indicated successful control of PEOXA partial hydrolysis and conjugation of benzophenone molecules to PEOXA chains. Ellipsometry and ATR-FTIR results showed that wavelength of UV light during C, H-insertion reaction influences stability of polymer network (hydrogel) on the substrate surface. XPS spectra verified that a stable film could be generated using suitable UV light during preparation of polymer network. Cell culture study on laminin/PEOXA-coated PMAA plastics showed dual-functional properties

Minat Calon Pengantin Terhadap Penggunaan Kontak Lensa Pada Tata Rias Pengantin

AbstrakBIDHARI SINTA MEI SASTI, Minat Calon Pengantin Terhadap Penggunaan Kontak Lensa Pada Tata Rias Pengantin. Tugas Akhir. Jakarta: Program Studi Diploma Tiga Tata Rias, Fakultas Teknik, Universitas Negeri Jakarta, 2021.Penelitian ini bertujuan untuk mengetahui sejauh mana minat calon pengantin terhadap penggunaan kontak lensa pada tata rias pengantin. Populasi penelitian adalah calon pengantin yang telah terdaftar menikah pada tahun 2021 di tiga sanggar yaitu, LKP Sanggar Rias Giyama, Sanggar Rias & Dekorasi Mbak Endang, dan Sanggar Rias Ophen House Manten dengan jumlah total sempel yaitu 38 orang. Penelitian ini dengan menggunakan metode deskriptif kuantitatif dengan menyebarkan kuesioner melalui google form kepada responden. Dengan demikian hasil penelitian yang diperoleh dari 6 aspek minat calon pengantin terhadap penggunaan kontak lensa pada tata rias pengantin bahwa aspek perasaan tertarik sebesar 75,65% kriteria berminat, perhatian sebesar 65,86% kriteria sangat ragu-ragu,perasaan senang sebesar 73,28% kriteria berminat, harapan sebesar 88,42% kriteria sangat berminat, kebutuhan sebesar 75,36% kriteria berminat, dan motivasi sebesar 83,3% kriteria berminat dan diperoleh hasil data domisili daerah menunjukkan bahwa Bekasi memperoleh hasil 99,68% dan Blora memperoleh hasil 74,71%. Maka dapat disimpulkan bahwa minat calon pengantin terhadap penggunaan kontak lensa pada tata rias pengantin memiliki presentase keseluruhan sebesar 76,97% masuk dalam kriteria berminat dan minat calon pengantin untuk domisili Bekasi lebih tinggi masuk dalam katagori sangat berminat dibandingkan dengan Blora masuk dalam katagori beminat.Kata kunci: Minat Calon Pengantin, Kontak Lensa, Tata Rias Penganti

Effect of Corporate Social Responsibility Information Disclosure on Financial Performance and Firm Value in Banking Industry Listed at Indonesia Stock Exchange

This study aims to analyze and explaining effect of corporate social responsibility information disclosure on financial performance and firm value in banking industry listed at Indonesia Stock Exchange. This study uses quantitative methods with positivism approach. Research objects were 15 banking companies listed at Indonesia Stock Exchange based on population criteria with observation period 2008-2011. This study uses secondary data derived from annual reports and financial statements. Data analysis used was Path Analysis. Research results show corporate social responsibility information disclosure affects on all financial performance measurement namely Return on Assets (ROA), Return on Equity (ROE) and Return on Sales (ROS). Corporate social responsibility information disclosure affect on firm value that measured by Tobin's Q. Financial performance that measured by ROA and ROE affect on firm value that measured by Tobin's Q, but ROS did not affect on firm value that measured by Tobin's Q. Keywords: Corporate Social Responsibility/CSR, financial performance, firm value, bankin

Nonfouling Surface Coatings Based on Poly(2-methyl-2-oxazoline)

Surface fouling, i.e. the non-specific surface adhesion of proteins, bacteria and higher organisms, poses a severe problem in many areas ranging from modern diagnostic and therapeutic medical devices to food processing and food wrapping technology to corrosion prevention and marine technology. One approach to address these problems is to coat surfaces with nonfouling polymers. The properties of a new class of nonfouling polymer coatings made from poly(2-methyl-2-oxazoline) (PMOXA) were investigated here in comparison with the most frequently used polymer in this context, poly(ethylene glycol) (PEG). Both polymers were side-chain grafted onto a polycationic poly-L-lysine (PLL) backbone. The PMOXA graft copolymers spontaneously self-assembled to form monolayers on negatively charged surfaces. PMOXA surface coatings were as efficient as PEG-based coatings in suppressing protein and bacterial adsorption. The minimal number of side chain monomer units per surface area that are needed to obtain fully resistant surfaces was lower though for PMOXA than for PEG graft copolymers as a result of the higher molecular weight of the PMOXA monomer unit

The synthesis of polymeric dual-functional antimicrobial surface based on poly(2-methyl-2-oxazoline)

There is a high interest in the development of antimicrobial coatings to fi ght bacterial infections.We present the development of dual-functional antimicrobial surface, in which a biopassive platform wasfunctionalized with bioactive compounds on the surface, using a graft copolymer system poly(L-lysine)-graftpoly(2-methyl-2-oxazoline)-quarternery ammonium compound (PLL-g-PMOXA-QAC). Alkyne functionalitywas introduced to the PMOXA chain at α-terminus by initiating the living cationic polymerization of 2-methyl-2-oxazoline with a propargylic-initiator. The reaction was terminated with carboxy derivative-terminator thatallows grafting of the polymeric chain from the β-terminus to poly(L-lysine) (PLL) backbone, resulting in graftcopolymer alkynyl PLL-g-PMOXA. The conjugation between alkynyl PLL-g-PMOXA and QAC was thenperformed using click reaction. The chemical structures of the polymers were characterized by MALDI-TOFspectrometry and NMR spectroscopy. The results demonstrate that we have successfully synthesized PLL-g-PMOXA-QAC copolymer with grafting density (number of lysine/number of PMOXA) of 0.33. The resultingPLL-g-PMOXA-QAC copolymer was then immobilized onto carboxylated tissue cultured polystyrene (TCPS)surface and exposed to bacteria solution to test its dual-functional properties. Preliminary live-and-deadbacteria study indicates dual-functionality of the PLL-g-PMOXA-QAC-coated surface

Pengaruh perbedaan jumlah penambahan binder uretan dan berbagai motif embossing terhadap kualitas kulit reject

Rejected tanned leather is tanned lether product with damages of more than 30% of its total surface area, but can be improved by embossing. Embossing is the provision of patterns that influences the properties of articles and contributes to the closure of the defects on the surface of leather. This study aims to determine the influence of urethane binder and embossing motives to the quality of rejected leather for shoe upper applications. Variables investigated were urethane binder composition (100, 150, and 200 part in 1000 part of base coat) and embossing motives (crocodile, ostrich, shark fish, and milled motive). The quality of the leather was then tested in terms of organoleptic properties (feel, flexibility, visual appearance), mechanical properties (tear strength, tensile strength, elongation at break, rub fastness (dry, wet), adhesive strength of cover paint (dry, wet), and flexing resistance), physical properties (WVP and WVA), as well as morphology (SEM). The results showed that the addition of urethane binder and embossing patterns affect the quality of shoe upper leather, i.e. in general covering the leather defects and increasing the visual appearance (organoleptic properties), and changing the collagen network structure (based on SEM test). Visually preferred skin is skin with the addition of 200 parts of the urethane binder and crocodile patterned leather.

Biodegradable plastics from linier low-density polyethylene and polysaccharide: The influence of polysaccharide and acetic acid

Global problems associated with conventional, non-biodegradable plastics have urged the society to use more eco-friendly biodegradable plastics. In this study, linear low-density polyethylene (LLDPE) was co-compounded with cassava-based thermoplastic starch (TPS) to prepare biodegradable plastics (i.e. plastics that can be degraded by microbes), in which three different LLDPE/TPS ratios were studied. Acetic acid was used to hydrolyze the polysaccharides by breaking the branched amylopectin that causes the TPS-containing composites brittle and stiff. The biodegradation properties of the LLDPE/TPS composites were determined by observing the level of microbial growth on the sample surface after incubation with potato dextrose agar medium that was inoculated with Penicillium sp. and Aspergillus niger. Burial test in a humid composting medium was also performed to validate the biodegradation properties. The mass change (%) was calculated in relative to the initial mass before burial test. The physical properties (tensile strength and elongation at break) of the bioplastics were determined using universal testing machine before and after burial treatment. The morphology of the sample surface was evaluated using scanning electron microscopy. The results showed that the microbial growth increases with increasing TPS content. Negative mass changes were observed on all samples that contain TPS, with increase in the magnitude with increasing TPS content.  The tensile strength tends to increase in the first 28 days of burial period in a composting medium then decreases and plateaus, while the elongation at break decreases with increasing burial period. Moreover, samples that contain acetic acid showed less microbial attachment and less biodegradation compared to samples that does not contain acetic acid