1,582 research outputs found
Using a Logic Programming Framework to Control Database Query Dialogues in Natural Language
We present a natural language question/answering system to interface the University of Évora databases that uses clarification dialogs in order to clarify user questions. It was developed in an integrated logic programming framework, based on constraint logic programming using the GnuProlog(-cx) language [2,11] and the ISCO framework [1]. The use of this LP framework allows the integration of Prolog-like inference mechanisms with classes and inheritance, constraint solving algorithms and provides the connection with relational databases, such as PostgreSQL. This system focus on the questions’ pragmatic analysis, to handle ambiguity, and on an efficient dialogue mechanism, which is able to place relevant questions to clarify the user intentions in a straightforward manner. Proper Nouns resolution and the pp-attachment problem are also handled.
This paper briefly presents this innovative system focusing on its ability to correctly determine the user intention through its dialogue capability
Social evaluation at a distance – facets of stereotype content about student groups in higher distance education
In the academic domain, belonging to a negatively stereotyped group can impair performance and peer relationships. In higher distance education, stereotypes may be particularly influential as face-to-face contact is limited and non-traditional students who are at risk of being stereotyped are overrepresented. Still, research on stereotypes in higher distance education is sparse. The current research addresses this gap by investigating the Big Two of social perception (warmth, competence) and subordinate facets (friendliness, morality, assertiveness, ability, conscientiousness) in the context of higher distance education. It tests a) how well models with warmth/competence or the facets fit the data, b) whether stereotypes in higher distance education depend on the student group, and c) how the Big Two and subordinate facets predict intergroup emotions and behavioral intentions in higher distance education. An online survey with N = 626 students (74% female) of a large distance university showed that a measurement model with four facets (i.e., friendliness, morality, ability, conscientiousness) reveals adequate model fit for 12 student groups. Perceived stereotypes were positive for female students, older students, and students with children. However, migrant as well as younger students were perceived negatively. Across groups, stereotype content facets predicted intergroup emotions and behavioral intentions of facilitation or harm. Implications for the influence of negative stereotypes in higher distance education are discussed
Temperature dependence of antiferromagnetic order in the Hubbard model
We suggest a method for an approximative solution of the two dimensional
Hubbard model close to half filling. It is based on partial bosonisation,
supplemented by an investigation of the functional renormalisation group flow.
The inclusion of both the fermionic and bosonic fluctuations leads in lowest
order to agreement with the Hartree-Fock result or Schwinger-Dyson equation and
cures the ambiguity of mean field theory . We compute the temperature
dependence of the antiferromagnetic order parameter and the gap below the
critical temperature. We argue that the Mermin-Wagner theorem is not
practically applicable for the spontaneous breaking of the continuous spin
symmetry in the antiferromagnetic state of the Hubbard model. The long distance
behavior close to and below the critical temperature is governed by the
renormalisation flow for the effective interactions of composite Goldstone
bosons and deviates strongly from the Hartree-Fock result.Comment: New section on critical behavior 31 pages,17 figure
Predicting the effects of deep brain stimulation using a reduced coupled oscillator model
This is the final version. Available on open access from Public Library of Science via the DOI in this recordData Availability: The data analysed in this manuscript is available from MRC BNDU Data Sharing platform at: https://data.mrc.ox.ac.uk/data-set/tremor-data-measured-essential-tremor-patients-subjected-phase-locked-deep-brain DOI: 10.5287/bodleian:xq24eN2KmDeep brain stimulation (DBS) is known to be an effective treatment for a variety of neurological disorders, including Parkinson’s disease and essential tremor (ET). At
present, it involves administering a train of pulses with constant frequency via electrodes implanted into the brain. New ‘closed-loop’ approaches involve delivering
stimulation according to the ongoing symptoms or brain activity and have the potential to provide improvements in terms of efficiency, efficacy and reduction of side effects. The success of closed-loop DBS depends on being able to devise a stimulation strategy that minimizes oscillations in neural activity associated with symptoms of motor disorders. A useful stepping stone towards this is to construct a mathematical model, which can describe how the brain oscillations should change when stimulation is applied at a particular state of the system. Our work focuses on the use of coupled oscillators to represent neurons in areas generating pathological oscillations. Using a reduced form of the Kuramoto model, we analyse how a patient should respond to stimulation when neural oscillations have a given phase and amplitude, provided a number of conditions are satisfied. For such patients, we predict that the best stimulation strategy should be phase specific but also that stimulation should have a greater effect if applied when the amplitude of brain oscillations is lower. We compare this surprising prediction with data obtained from ET patients. In light of our predictions, we also propose a new hybrid strategy which effectively combines two of the closed-loop strategies found in the
literature, namely phase-locked and adaptive DBS
Einführung und Etablierung einer Kultur des Wissenteilens in Organisationen
Die Bedeutung des Themenfeldes Wissensmanagement wird in der Literatur häufig mit der Vielzahl an Veröffentlichungen in der jüngsten Vergangenheit begründet. Weiterhin wird mit der zunehmenden Globalisierung und der damit verbundenen Intensivierung des Wettbewerbs im Hinblick auf Sicherung und Ausbau von Wettbewerbsvorteilen argumentiert. Demnach wird es immer wichtiger Daten, Fakten, Erfahrungen, Erkenntnisse, Informationen und gar das Wissen einer Organisation zu organisieren, zu lenken und zu managen. Die Betrachtung von Wissen als sogenannter vierter Produktionsfaktor ist selbstverständlich geworden. Dementsprechend ist die Bereitschaft von Organisationen, in Wissensmanagement-Systeme zu investieren, gestiegen
Nuclear Localization of HBD-1 in Human Keratinocytes
Objective: Human defensins and cathelicidins are a family of cationic antimicrobial peptides (AMPs), which play multiple roles in both innate and adaptive immune systems. They have direct antimicrobial activity against several microorganisms including burn pathogens. The majority of components of innate and adaptive immunity either express naturally occurring defensins or are otherwise chemoattracted or functionally affected by them. They also enhance adaptive immunity and wound healing and alter antibody production. All mechanisms to explain multiple functions of AMPs are not clearly understood. Prior studies to localize defensins in normal and burned skin using deconvolution fluorescence scanning microscopy indicate localization of defensins in the nucleus, perinuclear regions, and cytoplasm. The objective of this study is to further confirm the identification of HBD-1 in the nucleus by deconvolution microscopic studies involving image reconstruction and wire frame modeling. Results: Our study demonstrated the presence of intranuclear HBD-1 in keratinocytes throughout the stratum spinosum by costaining with the nuclear probe DAPI. In addition, HBD-1 sequence does show some homology with known cationic nuclear localization signal sequences. Conclusion: To our knowledge, this is the first report to localize HBD-1 in the nuclear region, suggesting a role for this peptide in gene expression and providing new data that may help determine mechanisms of defensin functions
Improving inpatient postnatal services: midwives views and perspectives of engagement in a quality improvement initiative
Background: despite major policy initiatives in the United Kingdom to enhance women's experiences of maternity care, improving in-patient postnatal care remains a low priority, although it is an aspect of care consistently rated as poor by women. As part of a systems and process approach to improving care at one maternity unit in the South of England, the views and perspectives of midwives responsible for implementing change were sought.
Methods: a Continuous Quality Improvement (CQI) approach was adopted to support a systems and process change to in-patient care and care on transfer home in a large district general hospital with around 6000 births a year. The CQI approach included an initial assessment to identify where revisions to routine systems and processes were required, developing, implementing and evaluating revisions to the content and documentation of care in hospital and on transfer home, and training workshops for midwives and other maternity staff responsible for implementing changes. To assess midwifery views of the quality improvement process and their engagement with this, questionnaires were sent to those who had participated at the outset.
Results: questionnaires were received from 68 (46%) of the estimated 149 midwives eligible to complete the questionnaire. All midwives were aware of the revisions introduced, and two-thirds felt these were more appropriate to meet the women's physical and emotional health, information and support needs. Some midwives considered that the introduction of new maternal postnatal records increased their workload, mainly as a consequence of colleagues not completing documentation as required.
Conclusions: this was the first UK study to undertake a review of in-patient postnatal services. Involvement of midwives at the outset was essential to the success of the initiative. Midwives play a lead role in the planning and organisation of in-patient postnatal care and it was important to obtain their feedback on whether revisions were pragmatic and achieved anticipated improvements in care quality. Their initial involvement ensured priority areas for change were identified and implemented. Their subsequent feedback highlighted further important areas to address as part of CQI to ensure best quality care continues to be implemented. Our findings could support other maternity service organisations to optimise in-patient postnatal services
Влияние неоднородностей температуры поверхности на теплообмен воздуха с Землей
В работе проведено моделирование процесса натекания воздуха с холодной поверхности воды на теплую поверхность суши и сравнение расчетов с результатами измерений. Из расчетов следует, что потоки тепла в прибрежной зоне могут более чем на 20% превышать значения потоков тепла, вычисленных из предположения о горизонтальной однородности приземного слоя. Таким образом, горизонтальную неоднородность атмосферы следует учитывать при расчетах охлаждения водоемов, горизонтальный размер которых имеет масштаб ~100 м.В роботі проведено моделювання процесу натікання повітря з холодної поверхні води на теплу поверхню суші та порівняння розрахунків із вимірюваннями. З розрахунків видно, що потоки тепла в прибережній зоні можуть більш ніж на 20% перевищувати значення потоків тепла, обчислених з припущення про горизонтальну однорідність приземного шару. Таким чином, горизонтальну неоднорідність атмосфери слід враховувати при розрахунках охолодження водойм, горизонтальний розмір яких має масштаб ~100 м.In the paper, the air flow process from the cold water surface onto the warm land surface was simulated. The comparisons of calculations with measurements were performed as well. The calculations show that the heat flux in the narrow coastal zone may be more than 20% higher than the values of heat fluxes calculated from the assumption of horizontal homogeneity of the surface layer. Thus, the horizontal inhomogeneity of the atmosphere must be taken into account in the calculation of the cooling water, the horizontal size of which has a scale of ~100 m
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Assimilation of 3D radar reflectivities with an ensemble Kalman filter on the convective scale
An ensemble data assimilation system for 3D radar reflectivity data is introduced for the convection-permitting numerical weather prediction model of the COnsortium for Small-scale MOdelling (COSMO) based on the Kilometre-scale ENsemble Data Assimilation system (KENDA), developed by Deutscher Wetterdienst and its partners. KENDA provides a state-of-the-art ensemble data assimilation system on the convective scale for operational data assimilation and forecasting based on the Local Ensemble Transform Kalman Filter (LETKF). In this study, the Efficient Modular VOlume RADar Operator is applied for the assimilation of radar reflectivity data to improve short-term predictions of precipitation. Both deterministic and ensemble forecasts have been carried out. A case-study shows that the assimilation of 3D radar reflectivity data clearly improves precipitation location in the analysis and significantly improves forecasts for lead times up to 4 h, as quantified by the Brier Score and the Continuous Ranked Probability Score. The influence of different update rates on the noise in terms of surface pressure tendencies and on the forecast quality in general is investigated. The results suggest that, while high update rates produce better analyses, forecasts with lead times of above 1 h benefit from less frequent updates. For a period of seven consecutive days, assimilation of radar reflectivity based on the LETKF is compared to that of DWD's current operational radar assimilation scheme based on latent heat nudging (LHN). It is found that the LETKF competes with LHN, although it is still in an experimental phase
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