3,740 research outputs found

    Change in Percentage of Families Offered Coverage at Work, 1998-2005

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    Uses data from the National Health Interview Survey to measure changes between 1998 and 2005 in the percentage of families with working adults that have at least one offer of health insurance through an employer

    THE PRIVATE HEALTH INSURANCE MARKET IN THE EUROPEAN UNION

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    Private health insurance serves three distinct functions in western European health systems. The first is as an alternative for mandatory (statutory) social health insurance arrangements. The second function is to supplement statutory insurance, providing coverage for services not covered by social insurance. A third function of private health insurance is to provide what can be termed complementary coverage, in which insured persons purchase additional private insurance even while they have to participate in existing social schemes.private health insurance, statutory health insurance, substitutive health insurance, complementary health insurance, supplementary health insurance.

    LAPORAN INDIVIDU PRAKTEK PENGALAMAN LAPANGAN SEMESTER KHUSUS TAHUN AKADEMIK 2014 SMA EL SHADAI MAGELANG

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    Pelaksanaan Praktik Pengalaman Lapangan (PPL) merupakan salah satu mata kuliah yang wajib ditempuh oleh mahasiswa S1 selama kurang lebih satu bulan terhitung dari tanggal 10 Agustus 2015 sampai tanggal 14 september 2015 sebagai salah satu syarat dalam menyelesaikan gelar sebagai sarjana pendidikan di Universitas Negeri Yogyakarta. Visi dari Praktik Pengalaman Lapangan adalah wahana pembentukan calon guru atau tenaga kependidikan yang profesional. Pelaksanaan KKN-PPL bertempat di SMA EL SHADAI Magelang, Jl. A. Yani 28 Magelang, Kecamatan Magelang Tengah, Kota Magelang. Praktik Pengalaman Lapangan (PPL) merupakan kegiatan pembelajaran di sekolah. Kegiatan PPL umumnya mencakup kegiatan belajar mengajar, membuat persiapan berupa Administrasi Guru (RPP, Program semester, Program Tahunan, dll) pengembangan media dan kegiatan lain yang berkaitan tentang proses belajar mengajar. Kegiatan PPL memberikan pengalaman luas kepada mahasiswa praktikan dalam bagaimana cara mengajar dengan berbagai macam karakter siswa, berinteraksi dengan pihak sekolah, mengabdi untuk kepentingan pendidikan yang secara langsung dapat dirasakan oleh mahasiswa. Pelaksanaan kegiatan PPL juga tidak akan terlepas dari berbagai kendala dan hambatan. Hambatan tersebut tentu dapat diatasi dengan bekerja keras, mau menerima masukan dari orang lain dan keinginan untuk memperbaiki diri

    Morphological, Structural and Spectral Mapping of the Central Uplifts of the Alga and Verlaine Craters, Mars

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    Impact cratering is a ubiquitous geological process that has shaped planetary bodies of the Solar System and beyond. While the impact cratering record on Earth has been poorly preserved, the Martian surface is characterized by a very old and cratered terrain. Central uplifts within complex impact craters are of particular interest as they expose deep-seated material, some of which may correspond to samples of the early Martian crust. Central uplift formation is, however, still a poorly understood geological process. This research investigated the origin of the exposed bedrock in the central uplifts of two Martian complex craters as well as the emplacement, distribution, and extent of allochthonous crater-fill deposits. This research entailed detailed decametre- to metre-scale mapping of morphological and structural observations with compositional analysis. Two complex craters located within Noachian-aged terrains, Alga (333.3 °E, 24.3 °S; ~19 km in diameter) and Verlaine (64.1 °E, -9.2 °S; ~39 km in diameter) were selected for this study. The exposed massive and fractured bedrock (MFB) in Alga is enriched in olivine and low-calcium pyroxene. Verlaine is characterized by MFB enriched in olivine, some of which is altered to Fe/Mg-rich clays, as well as megabrecciated bedrock. Both central uplifts are characterized by a diversity of potential impact melt-bearing lithologies that cover a major proportion of the uplifts. Structural mapping revealed that lineaments are oriented radially and concentrically, which corroborate structural assessments of terrestrial impact structures

    The Pain in Spain: Examining Andalusia\u27s Youth Unemployment Crisis

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    This paper examines the youth unemployment crisis in the autonomous community of Andalusia by assessing employment policies that are currently in place. Since the economic crisis nearly a decade ago, there has been very little change in the high rates of Andalusian youth unemployment, which as a whole, has left the region, the country and the European Union at risk due to a lack of inefficient policies. By utilizing anecdotal evidence paired with facts and figures released by the European Union, recommendations to adjust employment policies such as the Youth Guarantee and PRAEM are given in order to shine a light on the areas that are lacking effectiveness when it comes to solving the problem at hand rather than allowing it to continue

    From Naturally Occurring Tumor Immunity to Supernatural T Cells: Isolation and Characterization of a Murine T Cell Receptor Specific for Human Breast and Ovarian Tumor Antigen Cdr2

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    Patients with paraneoplastic cerebellar degeneration (PCD), a form of neuronal autoimmunity, have a co-occurring natural immune response against a protein called cdr2 in their breast and ovarian carcinomas, and thus provide an innovative starting point for understanding how to harness the immune system to fight cancer. We previously demonstrated cdr2-specific cytotoxic T lymphocytes (CTL) in the peripheral blood of HLA-A2.1+ PCD patients, suggesting that CTLs mediate tumor immunity in these patients. Cdr2 is expressed by a large proportion of breast and ovarian tumors from individuals who do not develop neurological disease, suggesting that immune responses to this antigen may develop independently of autoimmune responses. Here we explore establishing cdr2 as a target for breast and ovarian cancer immunotherapy by identifying naturally processed A2.1-restricted epitopes of cdr2. Immunization of A2.1 transgenic mice with recombinant adenovirus encoding human full length cdr2 led to the identification of two naturally processed A2.1-restricted human cdr2 peptides: cdr2(289-297) and cdr2(290-298). Mouse-derived A2.1-restricted cdr2(289-297)-specific CTLs were able to target cells expressing endogenous human cdr2, but also cross-reacted with endogenous mouse cdr2, resulting in partial tolerance to this epitope. In contrast, mouse-derived A2.1-restricted cdr2(290-298)-specific CTL were capable of recognizing tumor cells expressing endogenous human cdr2, but were unable to recognize mouse cdr2 due to nonhomology of the human and mouse cdr2(290- 298) epitopes. cdr2(290-298)-specific CTL clones were isolated, and their TCR gene cloned. Transfer of the mouse-derived TCR into human CD8+ T cells turned them into efficient cdr2-specific CTLs. We have detected CD8+ T cells specific for both cdr2(289-297) and cdr2(290-298) in peripheral blood from A2.1+ PCD patients by tetramer staining. This correlates the presence of T cells specific to these epitopes with PCD and effective anti-gynecologic tumor immunity, and suggests that these are bona fide tumor-associated CTL epitopes. We conclude swthat gene transfer of TCR specific for cdr2(290-298) could provide the basis for potent breast and ovarian cancer immunotherapies, while cdr2(289-297)-specific T cells, able to target both mouse and human cdr2, offer a platform for generating a humanized animal model to investigate the whether cdr2-TCR gene transfer is possible without inducing neuronal autoimmunity

    Computer Assembly of Cluster-Forming Amphiphilic Dendrimers

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    Recent theoretical studies have predicted a new clustering mechanism for soft matter particles that interact via a certain kind of purely repulsive, bounded potentials. At sufficiently high densities, clusters of overlapping particles are formed in the fluid, which upon further compression crystallize into cubic lattices with density-independent lattice constants. In this work we show that amphiphilic dendrimers are suitable colloids for the experimental realization of this phenomenon. Thereby, we pave the way for the synthesis of such macromolecules, which form the basis for a novel class of materials with unusual properties.Comment: 4 pages, 4 figures, 1 tabl
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