Contemporary educational discourse as a tool of modernization of higher education

 The article deals with the analysis of different approaches to definition of category of educational discourse in various fields of humanities in particular. Special attention was drawn towards explanation the notion of educational discourse. According to the author it means a type of institutional communication with a regulatory orientation, the purpose of which is the socialization of a new member of society, the transfer to him of certain knowledge, abilities, skills, social values. The article proves that educational discourse creates positive educational communication between participants of educational process and resulted in positive knowledge transfer. Also, the author outlines the structural components of educational discourse, explains it role within the educational process. the findings show that effective educational discourse applied between the partciipants of educational process help to build a positive educational environment and, in the long run, modernize higher education

Впровадження гейміфікації в корпоративному навчанні та розвитку персоналу сучасної організації

The article reviews the modern phenomenon of gamification in relation to corporate training of personnel. Examples of using gamification in different educational programs and corporate format are analyzed and provided. The peculiarities of implementation of gamification depending on age groups of participants are reviewed.Keywords: gamification, personnel training, corporate training, implementation of gamification В статті розглядається сучасний феномен гейміфікації стосовно до корпоративного навчання персоналу Аналізуються та приводяться приклади застосування гейміфікації в різних навчальних програмах та корпоративному форматі. Розглядаються особливості впровадження гейміфікації в залежності від вікових груп учасників. Ключові слова: гейміфікація, навчання персоналу, корпоративне навчання, впровадження гейміфікації

Techno-mathematical literacies in the workplace: a critical skills gap

There has been a radical shift in the mathematical skills required in modern workplaces. With the ubiquity of IT, employees now require Techno-mathematical Literacies, the mastery of new kinds of mathematical knowledge shaped by the systems that govern their work. The education system does not fully recognise these skills, employees often lack them, and companies struggle to improve them. This project has developed prototype learning resources to train a variety of employees in the mathematical awareness and knowledge that today’s employment require

Challenges of experimental research in education

To modernize the national system of education, to enhance teachers’ excellence or even to change the direction of professional teaching activity, it is important to upgrade pedagogical science and provide its practical orientation. In this regard, there is a necessity to look differently at the role and methods of experimental research in education. Accordingly, modern educator must fulfill the requirements of modern society; he/she be creative and learned, be able to analyze the experience and see prospects that means to be a researcher. The existing views on experimental research are developed under conditions of functioning of stable or standard programme in the unified state school. But currently, institutional diversity and a wide range of teaching methods can be considered the most significant features of educational system. These features suggest that pedagogical staff at the institution can design and implement their own educational technologies. Consequently, we observe a sharp increase in number of teaching approaches and methods within the educational process that leads to the explosive growth of pedagogical phenomena

Foreword

Welcome to the inaugural edition of the Annals of Innovation in Medicine! It is with great pleasure and enthusiasm that I introduce this landmark publication, which marks the beginning of a remarkable journey towards advancing healthcare through research and discovery. The creation of this journal has been driven by a shared vision among a diverse group of esteemed professionals who recognize the paramount importance of fostering innovation and collaboration in the field of medicine. Our mission is clear: to provide a platform for groundbreaking research, to encourage interdisciplinary dialogue, and to inspire transformative change that benefits patients and healthcare systems worldwide. In today\u27s rapidly evolving healthcare landscape, innovation is not just a buzzword; it is an imperative. We are witnessing extraordinary advancements in technology, diagnostic techniques, therapeutic interventions, and healthcare delivery models. The potential for improving patient outcomes and transforming the way we practice medicine has never been greater. It is our duty as researchers, clinicians, and healthcare professionals to embrace this era of innovation and push the boundaries of medical knowledge. The Annals of Innovation in Medicine is dedicated to showcasing the cutting-edge work that is shaping the future of healthcare. We welcome submissions from all corners of the medical community, be it original research articles, systematic reviews, case reports, or thought-provoking perspectives. By providing a platform for the dissemination of knowledge and ideas, we aim to catalyze collaboration, inspire creativity, and foster meaningful change. As the Editor of this esteemed journal, I am committed to maintaining the highest standards of scientific integrity, editorial excellence, and transparency. Each article published in the Annals of Innovation in Medicine will undergo a rigorous peer-review process to ensure that only the most impactful and reliable research finds its way into our pages. We strive to provide our readers with thoughtfully curated content that informs, challenges, and inspires. I would like to express my sincere gratitude to the dedicated reviewers, esteemed editorial board members, and the entire team who have worked tirelessly to bring this vision to life. Without their expertise, passion, and commitment, this journal would not have been possible. I also extend my appreciation to the authors who have entrusted us with their innovative research. Your contributions are invaluable, and we are honored to have the opportunity to showcase your work. I invite all readers, authors, and reviewers to join us on this exciting journey as we explore the frontiers of medical innovation. Together, let us push the boundaries of knowledge, revolutionize patient care, and shape the future of medicine.   Warm regards, Dr. Preet Pal Singh Bhinder Editor, Annals of Innovation in Medicin

Effectiveness of corticosteroids in the treatment of patients with Covid 19

The COVID-19 pandemic caused by the SARS-CoV-2 virus has emerged as one of the most significant health crises of the 21st century, with a devastating impact on global health. Understanding the disease pathogenesis and finding effective treatment strategies are crucial to mitigate its mortality rate. COVID-19 exhibits a biphasic illness, characterized by a viral response phase followed by a hyperinflammatory response phase, also known as the cytokine storm. This cytokine storm, rather than direct viral activity, has been identified as the major contributor to the high mortality associated with severe cases. In this article, we explore the effectiveness of corticosteroids in managing the cytokine storm and reducing mortality in COVID-19. Corticosteroids have been extensively studied for their immunosuppressive properties and have shown potential in suppressing the hyperinflammatory response associated with the disease. The RECOVERY trial, a large-scale multicenter clinical trial conducted in the UK, demonstrated a significant reduction in mortality with the use of corticosteroids, particularly in critically ill patients requiring invasive mechanical ventilation. However, the timing of corticosteroid therapy initiation is crucial, as early administration or use in milder cases may not yield the same benefits and could potentially increase mortality. Current evidence suggests that corticosteroids should be reserved for hospitalized patients with severe COVID-19, specifically those requiring oxygen therapy or invasive mechanical ventilation. In contrast, corticosteroid therapy has shown limited or even detrimental effects in non-severe cases

Genotoxicity evaluation of pesticide profenofos by applying dominant lethal test on Culex quinquefasciatus

The present paper deals with the genotoxicity evaluation of profenofos by applying dominant lethal test (DLT) on Culex quinquefasciatus taken as an experimental model. For this, the males hatched from the larvae treated with LC20 of pesticide were crossmated with normal females and the results were based on the number of hatched and unhatched eggs laid by these females. Mean percentage frequency of unhatched eggs was as low as 3.97 in the normal stocks as compared to treated stocks in which the frequency of unhatched eggs had increasedto 9.50. The statistical analysis of the data from treated groups gave values of 9.50±1.35 as against 3.97± 0.38 in the control groups. Profenofos induced significant (p<0.05) dominant lethality

Effect of Internal and External Concentration Polarizations on the Performance of Forward Osmosis Process

Forward osmosis (FO) as an osmotically driven membrane process is severely affected by the concentration polarization phenomenon on both sides of the membrane as well as inside the support layer. Though the effect of internal concentration polarization (ICP) in the porous support on the draw solution side is far more pronounced than that of the external concentration polarization (ECP), still the importance of ECP cannot be neglected. The ECP becomes particularly important when the feed flow rate is enhanced to increase the permeation flux by increasing the agitation and turbulence on the membrane surface. To capture the effect of ECP a suitable value of mass transfer coefficient must be determined. In this chapter, an FO mass transport model that accounts for the presence of both ICP and ECP phenomena is first presented on the basis of solution-diffusion model coupled with diffusion-convection. Then, three methods for the estimation of mass transfer coefficient based on empirical Sherwood (Sh) number correlations, pressure-driven reverse osmosis (RO), and osmosis-driven pressure retarded osmosis (PRO) are proposed. Finally, a methodology for the prediction of water flux through FO membranes using the theoretical model and calculated/measured parameters (hydraulic permeability, salt resistivity of the support layer, and mass transfer coefficient) is presented

Nimbecidine induced gene mutations in internal transcribed spacers 1 and 2 of Anopheles stephensi

The genotoxic effects of nimbecidine, a commercial botanical pesticide derived from the neem tree were assessed by PCR assay on a mosquito Anopheles stephensi taken as an experimental model. After treatment with LC20 of the nimbecidine, the sequence variations in the internal transcribed spacers 1 and 2 (ITS1 and ITS2) of control and treated individuals were studied from their sequence alignment data and the mutations in the form of insertions, deletions, and substitutions were analyzed. Nimbecidine treatment induced 16 deletions, 13 insertions, 93 transitions and 140 transversions in the ITS1 sequence. Similarly, in the ITS2 sequence of treated individual there were 2 deletions, 4 insertions, 15 transitions and 39 transversions. Present study suggests that plant based pesticides also effect the integrity of normal DNA sequences