51 research outputs found

    Particle Diffusion and Acceleration by Shock Wave in Magnetized Filamentary Turbulence

    Full text link
    We expand the off-resonant scattering theory for particle diffusion in magnetized current filaments that can be typically compared to astrophysical jets, including active galactic nucleus jets. In a high plasma beta region where the directional bulk flow is a free-energy source for establishing turbulent magnetic fields via current filamentation instabilities, a novel version of quasi-linear theory to describe the diffusion of test particles is proposed. The theory relies on the proviso that the injected energetic particles are not trapped in the small-scale structure of magnetic fields wrapping around and permeating a filament but deflected by the filaments, to open a new regime of the energy hierarchy mediated by a transition compared to the particle injection. The diffusion coefficient derived from a quasi-linear type equation is applied to estimating the timescale for the stochastic acceleration of particles by the shock wave propagating through the jet. The generic scalings of the achievable highest energy of an accelerated ion and electron, as well as of the characteristic time for conceivable energy restrictions, are systematically presented. We also discuss a feasible method of verifying the theoretical predictions. The strong, anisotropic turbulence reflecting cosmic filaments might be the key to the problem of the acceleration mechanism of the highest energy cosmic rays exceeding 100 EeV (10^{20} eV), detected in recent air shower experiments.Comment: 39 pages, 2 figures, accepted for publication in Ap

    Tissue- and sex-specific small RNAomes reveal sex differences in response to the environment.

    Get PDF
    RNA interference (RNAi) related pathways are essential for germline development and fertility in metazoa and can contribute to inter- and trans-generational inheritance. In the nematode Caenorhabditis elegans, environmental double-stranded RNA provided by feeding can lead to heritable changes in phenotype and gene expression. Notably, transmission efficiency differs between the male and female germline, yet the underlying mechanisms remain elusive. Here we use high-throughput sequencing of dissected gonads to quantify sex-specific endogenous piRNAs, miRNAs and siRNAs in the C. elegans germline and the somatic gonad. We identify genes with exceptionally high levels of secondary 22G RNAs that are associated with low mRNA expression, a signature compatible with silencing. We further demonstrate that contrary to the hermaphrodite germline, the male germline, but not male soma, is resistant to environmental RNAi triggers provided by feeding, in line with previous work. This sex-difference in silencing efficacy is associated with lower levels of gonadal RNAi amplification products. Moreover, this tissue- and sex-specific RNAi resistance is regulated by the germline, since mutant males with a feminized germline are RNAi sensitive. This study provides important sex- and tissue-specific expression data of miRNA, piRNA and siRNA as well as mechanistic insights into sex-differences of gene regulation in response to environmental cues.This work was funded by grants from the Swiss National Science Foundation and an advanced European Research Council grant to Laurent Keller, grants from Cancer Research UK (C13474/A18583, C6946/A14492) and the Wellcome Trust (104640/ Z/14/Z, 092096/Z/10/Z) to Eric A. Miska, and grants from the National Institutes of Health to Sean M. West (NIGMSNHRA 5F32GM100614) and to Fabio Piano and Kristin Gunsalus (NHGRI U01 HG004276, NICHD R01 HD046236), and by research funding from New York University Abu Dhabi to Fabio Piano and Kristin Gunsalus

    Reading tea leaves worldwide: Decoupled drivers of initial litter decomposition mass‐loss rate and stabilization

    Get PDF
    The breakdown of plant material fuels soil functioning and biodiversity. Currently, process understanding of global decomposition patterns and the drivers of such patterns are hampered by the lack of coherent large-scale datasets. We buried 36,000 individual litterbags (tea bags) worldwide and found an overall negative correlation between initial mass-loss rates and stabilization factors of plant-derived carbon, using the Tea Bag Index (TBI). The stabilization factor quantifies the degree to which easy-to-degrade components accumulate during early-stage decomposition (e.g. by environmental limitations). However, agriculture and an interaction between moisture and temperature led to a decoupling between initial mass-loss rates and stabilization, notably in colder locations. Using TBI improved mass-loss estimates of natural litter compared to models that ignored stabilization. Ignoring the transformation of dead plant material to more recalcitrant substances during early-stage decomposition, and the environmental control of this transformation, could overestimate carbon losses during early decomposition in carbon cycle models

    Reading tea leaves worldwide: decoupled drivers of initial litter decomposition mass‐loss rate and stabilization

    Get PDF
    The breakdown of plant material fuels soil functioning and biodiversity. Currently, process understanding of global decomposition patterns and the drivers of such patterns are hampered by the lack of coherent large‐scale datasets. We buried 36,000 individual litterbags (tea bags) worldwide and found an overall negative correlation between initial mass‐loss rates and stabilization factors of plant‐derived carbon, using the Tea Bag Index (TBI). The stabilization factor quantifies the degree to which easy‐to‐degrade components accumulate during early‐stage decomposition (e.g. by environmental limitations). However, agriculture and an interaction between moisture and temperature led to a decoupling between initial mass‐loss rates and stabilization, notably in colder locations. Using TBI improved mass‐loss estimates of natural litter compared to models that ignored stabilization. Ignoring the transformation of dead plant material to more recalcitrant substances during early‐stage decomposition, and the environmental control of this transformation, could overestimate carbon losses during early decomposition in carbon cycle models

    The HER3 receptor: Role as an intervention target in ovarian cancer

    No full text

    Datenanalyse einer Beobachtung des Quasars 3C 273 im Hochenergie-Roentgenbereich und die Bedeutung fuer astrophysikalische Modelle

    No full text
    Copy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman
    • 

    corecore