Twin pregnancies: a retrospective analysis

Background: This study aims to analyse the maternal and neonatal complications in twin pregnancy at tertiary institute.Methods: This was a retrospective study of multiple pregnancies after 26 weeks gestation at a tertiary teaching hospital between January 2020 to December 2020. Maternal and neonatal data was collected from the labour room delivery register and NICU records.Results: Out of 1212 births during this period, 66 were twin pregnancies with an incidence of 5.54%. Most of women had twinning after in vitro fertilisation (IVF) treatment (77.27%). Thirty-seven (56.06%) women were in the age group of 21-30 years and primigravida contributed to 63.63% of all twin pregnancies. Maternal complications most frequently noticed was hypertensive disorders of pregnancy in 27 (40.90%) women, Gestational diabetes mellitus (GDM) in 24 (36.36%) women, preterm rupture of membranes (PROM)/ preterm premature rupture of membranes (PPROM) in 21 (31.18%) women, Intrahepatic cholestasis of pregnancy (IHCP) in 4 (6.06%) women, hypothyroidism in 12 (18.8.1%) women and antepartum hemorrhage (APH) in 4 (6.06%). Caesarean section was performed on 49 (74.25%) women with abnormal presentation as indication in 18 (36.73%). 80.30% women had preterm delivery with 86 (65.15 %) neonates having NICU admission. There was no maternal mortality and 1 (1,16 %) perinatal mortality in NICU admitted neonates.Conclusions: This study reveals with increasing ART treatment the incidence of twin pregnancies is increasing along with its maternal complications like hypertensive disorders of pregnancy, GDM and preterm delivery. Frequent antenatal care for early detection of complications, multi-disciplinary approach is key for favourable outcome.

Fabrication and characterization of dual function nanoscale pH-scanning ion conductance microscopy (SICM) probes for high resolution pH mapping

The easy fabrication and use of nanoscale dual function pH-scanning ion conductance microscopy (SICM) probes is reported. These probes incorporate an iridium oxide coated carbon electrode for pH measurement and an SICM barrel for distance control, enabling simultaneous pH and topography mapping. These pH-SICM probes were fabricated rapidly from laser pulled theta quartz pipets, with the pH electrode prepared by in situ carbon filling of one of the barrels by the pyrolytic decomposition of butane, followed by electrodeposition of a thin layer of hydrous iridium oxide. The other barrel was filled with an electrolyte solution and Ag/AgCl electrode as part of a conductance cell for SICM. The fabricated probes, with pH and SICM sensing elements typically on the 100 nm scale, were characterized by scanning electron microscopy, energy-dispersive X-ray spectroscopy, and various electrochemical measurements. They showed a linear super-Nernstian pH response over a range of pH (pH 2–10). The capability of the pH-SICM probe was demonstrated by detecting both pH and topographical changes during the dissolution of a calcite microcrystal in aqueous solution. This system illustrates the quantitative nature of pH-SICM imaging, because the dissolution process changes the crystal height and interfacial pH (compared to bulk), and each is sensitive to the rate. Both measurements reveal similar dissolution rates, which are in agreement with previously reported literature values measured by classical bulk methods

Measuring the burden of infodemics : summary of the methods and results of the fifth WHO infodemic management conference

Background: An infodemic is excess information, including false or misleading information, that spreads in digital and physical environments during a public health emergency. The COVID-19 pandemic has been accompanied by an unprecedented global infodemic that has led to confusion about the benefits of medical and public health interventions, with substantial impact on risk-taking and health-seeking behaviors, eroding trust in health authorities and compromising the effectiveness of public health responses and policies. Standardized measures are needed to quantify the harmful impacts of the infodemic in a systematic and methodologically robust manner, as well as harmonizing highly divergent approaches currently explored for this purpose. This can serve as a foundation for a systematic, evidence-based approach to monitoring, identifying, and mitigating future infodemic harms in emergency preparedness and prevention. Objective: In this paper, we summarize the Fifth World Health Organization (WHO) Infodemic Management Conference structure, proceedings, outcomes, and proposed actions seeking to identify the interdisciplinary approaches and frameworks needed to enable the measurement of the burden of infodemics. Methods: An iterative human-centered design (HCD) approach and concept mapping were used to facilitate focused discussions and allow for the generation of actionable outcomes and recommendations. The discussions included 86 participants representing diverse scientific disciplines and health authorities from 28 countries across all WHO regions, along with observers from civil society and global public health–implementing partners. A thematic map capturing the concepts matching the key contributing factors to the public health burden of infodemics was used throughout the conference to frame and contextualize discussions. Five key areas for immediate action were identified. Results: The 5 key areas for the development of metrics to assess the burden of infodemics and associated interventions included (1) developing standardized definitions and ensuring the adoption thereof; (2) improving the map of concepts influencing the burden of infodemics; (3) conducting a review of evidence, tools, and data sources; (4) setting up a technical working group; and (5) addressing immediate priorities for postpandemic recovery and resilience building. The summary report consolidated group input toward a common vocabulary with standardized terms, concepts, study designs, measures, and tools to estimate the burden of infodemics and the effectiveness of infodemic management interventions. Conclusions: Standardizing measurement is the basis for documenting the burden of infodemics on health systems and population health during emergencies. Investment is needed into the development of practical, affordable, evidence-based, and systematic methods that are legally and ethically balanced for monitoring infodemics; generating diagnostics, infodemic insights, and recommendations; and developing interventions, action-oriented guidance, policies, support options, mechanisms, and tools for infodemic managers and emergency program managers.peer-reviewe

Structures and morphotectonic evolution of the frontal fold-thrust belt, Kameng river section, Arunachal Himalaya, India

The Neogene-Quaternary Siwalik foreland fold and thrust belt is studied for better understanding of tectonics along the Kameng river section of Arunachal Pradesh, India. The Kimi, Dafla, Subansiri, and the Kimin Formation correspond to Lower, Middle and Upper Siwaliks, respectively. The lithology in the foreland basin is dominantly sandstones, siltstones, claystones, carbonaceous shales, and boulder beds in the upper part. The structural style of the sedimentary sequence from the Main Boundary Thrust southward shows first order ramp-flat geometry. The brittle shear transfers slip across glide horizons to shallower depth. Repeated splay generations from a major regional-scale floor transfers slip from one glide horizon to another that shortens and thickens the crust. In the micro-scale, the lithological response in the structural development is well documented as pressure solution seams and other diagenetic deformation signatures. The basement asperity plays a significant role as the moving thrust front produced a major lateral ramp. The differential movement of the mountain front on both sides of the ramp is decipherable. This is especially true at the western part of the SE flowing Kameng river. The tectonic evolution of the area initiated with slip along the MBT 11 Ma ago along with the deposition of the Siwalik sediments. With southward propagation of the mountain front, the foreland basin shifted towards S, produced splay thrusts from the Himalayan Frontal Thrust-1 (HFT-1), which has been uplifting the Kimin and the older terraces

Provenance Shifts During Neogene Brahmaputra Delta Progradation Tied to Coupled Climate and Tectonic Change in the Eastern Himalaya

The Bengal Basin preserves the erosional signals of coupled tectonic-climatic change during late Cenozoic development of the Himalayan orogen, yet regional correlation and interpretation of these signals remains incomplete. We present a new geologic map of fluvial-deltaic deposits of the Indo-Burman Ranges (IBR), five detrital zircon fission track analyses, and twelve high-n detrital zircon U-Pb age distributions (dzUPb) from the Barail (late Eocene–early Miocene), Surma (early–late Miocene), and Tipam (late Miocene–Pliocene) Groups of the ancestral Brahmaputra delta. We use dzUPb statistical tests to correlate the IBR units with equivalent age strata throughout the Bengal Basin. An influx of trans-Himalayan sediment and the first appearance of ∼50 Ma grains of the Gangdese batholith in the lower Surma Group (∼18–15 Ma) records the early Miocene arrival of the ancestral Brahmaputra delta to the Bengal Basin. Contributions from Himalayan sources systematically decrease up section through the late Miocene as the contribution of Trans-Himalayan Arc sources increases. The Miocene (∼18–8 Ma) deposition of the Surma Group records upstream expansion of the ancestral Brahmaputra River into southeastern Tibet. Late Miocene (<8 Ma) progradation of the fluvial part of the delta (Tipam Group) routed trans-Himalayan sediment over the shelf edge to the Nicobar Fan. We propose that Miocene progradation of the ancestral Brahmaputra delta reflects increasing rates of erosion and sea level fall during intensification of the South Asian Monsoon after the Miocene Climate Optimum, contemporaneous with a pulse of tectonic uplift of the Himalayan hinterland and Tibet. © 2021 The Authors.Open access articleThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

29 Business Risk And Financial Risk- Indian Corporate

7 Impact of peripheral cues on rural consumer buying decision for FMCG products with special reference t

10 Be systematics in the Tsangpo-Brahmaputra catchment: the cosmogenic nuclide legacy of the eastern Himalayan syntaxis

International audienceThe Tsangpo-Brahmaputra River drains the eastern part of the Himalayan range and flows from the Tibetan Plateau through the eastern Himalayan syntaxis downstream to the Indo-Gangetic floodplain and the Bay of Bengal. As such, it is a unique natural laboratory to study how denudation and sediment production processes are transferred to river detrital signals. In this study, we present a new Be-10 data set to constrain denudation rates across the catchment and to quantify the impact of rapid erosion within the syntaxis region on cosmogenic nuclide budgets and signals. The measured Be-10 denudation rates span around 2 orders of magnitude across individual catchments (ranging from 0.03 to > 4 mm yr(-1)) and sharply increase as the Tsangpo-Brahmaputra flows across the eastern Himalaya. The increase in denudation rates, however, occurs similar to 150 km downstream of the Namche Barwa-Gyala Peri massif (NBGPm), an area which has been previously characterized by extremely high erosion and exhumation rates. We suggest that this downstream lag is mainly due to the physical abrasion of coarse-grained, low Be-10 concentration, landslide material produced within the syntaxis that dilutes the upstream high-concentration Be-10 flux from the Tibetan Plateau only after abrasion has transferred sediment to the studied sand fraction. A simple abrasion model produces typical lag distances of 50 to 150 km compatible with our observations. Abrasion effects reduce the spatial resolution over which denudation can be constrained in the eastern Himalayan syntaxis. In addition, we also highlight that denudation rate estimates are dependent on the sediment connectivity, storage, and quartz content of the upstream Tibetan Plateau part of the catchment, which tends to lead to an overestimation of downstream denudation rates. While no direct Be-10 denudation measurements were made in the syntaxis, the dilution of the upstream Be-10 signal, measured in Tsangpo-Brahmaputra sediments, provides constraints on the denudation rates in that region. These denudation estimates range from ca. 2 to 5 mm yr(-1) for the entire syntaxis and ca. 4 to 28 mm yr(-1) for the NBGPm, which is significantly higher than other large catchments. Overall, Be-10 concentrations measured at the outlet of the Tsangpo-Brahmaputra in Bangladesh suggest a sediment flux between 780 and 1430 Mt yr(-1) equivalent to a denudation rate between 0.7 and 1.2 mm yr(-1) for the entire catchment