Risk Factors Associated with Invasive Cervical Carcinoma among Women Attending Jimma University Specialized Hospital, Southwest Ethiopia: A Case Control Study

BACKGROUND: Cervical cancer is a more serious public health problem than other cancers in women in Sub-Saharan Africa in general and in Ethiopia in particular. Thus, this study assessed risk factors related to invasive cervical carcinomas in southwestern Ethiopia.METHODS: Unmatched case control study was conducted in Jimma University Specialized Hospital from April 1 to September 30, 2010. The study consisted of 60 cases (women who had cervical cancers based on histopathologic examination) and 120 controls (women with no cervical cancers). Semi-structured questionnaire was utilized for data collection. Vaginal examinations often visualized with speculum insertions were done for both cases and controls. Punch cervical biopsies were then performed for the suspected cases at Jimma University Hospital that serves about 15 million people in a catchment radius of 250 kms. Data were analyzed using SPSS version 13.0 software. Univariate and multivariate analyes were done to describe and identify independent predictors of cervical cancer.RESULTS: The mean ages of cases and controls were 47.7 (SD=10.8) and 35.5 (SD =10.5) years respectively. Older women (40-59 years), (OR= 4.7; 95%CI= 2.3-9.6), more than one husband (OR= 2.0; 95%CI=1.0-3.9), as well as more than one wife in lifetime, (OR= 3.0; 95% CI= 1.5-5.9), women who had more than 4 children, (OR =10.3, 95% CI= 3.6-29.0), and age greater than 25 years at first full term delivery, (OR= 8.8; 95% CI= 3.5-22.0) were statistically significant and the latter two were  independently associated with invasive cervical cancer. Only 7(11.7 %) of cases and 58(48.3%) of  controls ever heard of cervical cancers; however, 2(3.3%) of cases and 7(5.8%) of controls had ever had history of papaneocolous (pap) smear tests done.CONCLUSION: Poor knowledge on cervical cancer was observed that required more work to be done to increase knowledge of mothers on cervical cancer and on associated risk factors. Behavioral  communication activities and establishment of cervical cancer screening programs for the young could help reduce the advancement of cervical cancer particularly among the less knowledgeable, older and grand multiparous women in our parts of the world.KEYWORDS: invasive cervical carcinoma, risk factors, Jimma, south west Ethiopi

Summary of research for development ‘best practice’ technologies validated in the Africa RISING Endamehoni site in Ethiopia, 2013-2016

United States Agency for International Developmen

Livestock: Africa RISING science, innovations and technologies with scaling potential from the Ethiopian Highlands

United States Agency for International Developmen

Inoculation and P fertilizer improves food and feed production in grain legumes: Farmers' perceptions and treatment effects on yield and quality of residue biomass in Ethiopian highlands

Bill & Melinda Gates Foundatio

Constraints of small-scale irrigated fodder production and nutrition assessment for livestock feed, a case study in Ethiopia

Livestock is an integral part of the agricultural system in sub-Saharan Africa, serving as a food source, income, fertilizer, and power for farming and transportation. However, the productivity of the livestock system has been hampered due to a lack of sufficient quantity and quality feed. This study evaluates the gaps and constraints of fodder and nutritional potential for livestock feed using small-scale irrigation (SSI). The study comprised of 30 randomly selected farmers from two different ecological zones in Ethiopia. Half of the farmers cultivated Napier grass (Pennisetum purpureum) in the Robit watershed in northern Ethiopia, and the other half cultivated mixed vetch (Lathyrus cicera) and oats (Avena sativa) in Lemo watershed in southern Ethiopia. The Soil and Water Assessment Tool (SWAT) and Agricultural Policy Environmental eXtender (APEX) were applied in an integrated manner to assess the impacts of SSI at the watershed and field-scale levels, respectively. The watershed-scale analysis showed that there is a substantial amount of surface runoff and shallow groundwater recharge that could be used for dry season fodder production using irrigation. Field data calibrated APEX model indicated that Napier yield could be maximized with 550 mm of water in Robit watershed. While in the Lemo watershed, maximum vetch and oats yield may be achieved with 250 mm of water. The major constraints for Napier and oats production in the study sites were soil fertility, especially nitrogen and phosphorus, and vetch production was limited by high temperature. Fodder samples were collected at the time of harvest to evaluate feed quality. The nutritional analysis indicated that Napier grass has a higher dry matter and ash (mineral) content compared to oats and vetch. However, vetch has higher crude protein content (18%) compared to Napier (10%) and oats (6%). Overall the study indicated that cultivating vetch provided superior performance in terms of providing quality feed and environmental services

Comparison of the global prevalence and trend of human intestinal carriage of ESBL-producing Escherichia coli between healthcare and community settings: a systematic review and meta-analysis

Objectives:The widespread intestinal carriage of ESBL-producing Escherichia coli (ESBL E. coli) among both patients and healthy individuals is alarming. However, the global prevalence and trend of this MDR bacterium in healthcare settings remains undetermined. To address this knowledge gap, we performed a comparative meta-analysis of the prevalence in community and healthcare settings.Methods:Our systematic review included 133 articles published between 1 January 2000 and 22 April 2021 and indexed in PubMed, EMBASE or Google Scholar. A random-effects meta-analysis was performed to obtain the global pooled prevalence (community and healthcare settings). Subgroup meta-analyses were performed by grouping studies using the WHO regions and 5 year intervals of the study period.Results:We found that 21.1% (95% CI, 19.1%-23.2%) of inpatients in healthcare settings and 17.6% (95% CI, 15.3%-19.8%) of healthy individuals worldwide carried ESBL E. coli in their intestine. The global carriage rate in healthcare settings increased 3-fold from 7% (95% CI, 3.7%-10.3%) in 2001-05 to 25.7% (95% CI, 19.5%-32.0%) in 2016-20, whereas in community settings it increased 10-fold from 2.6% (95% CI, 1.2%-4.0%) to 26.4% (95% CI, 17.0%-35.9%) over the same period.Conclusions:The global and regional human intestinal ESBL E. coli carriage is increasing in both community and healthcare settings. Carriage rates were generally higher in healthcare than in community settings. Key relevant health organizations should perform surveillance and implement preventive measures to address the spread of ESBL E. coli in both settings

Feeds and forage action research in the Africa RISING sites of the Ethiopian highlands

United States Agency for International Developmen