285 research outputs found

    Community-based education and service: the HPSISN experience

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    Health services delivery is increasingly shifting to community-based settings. The competencies required of future health professionals require a shift in their educational preparation. Service leaning is suggested as an educational method with the potential to reform health professions education in tandem with the changes occurring in the health services delivery. The Health Professions Schools in Service to the Nation Program (HPSISN), a US demonstration project of service learning in the health professions, examines the impact of service leaning on students, faculty, communities and institutions across a wide array of universities and community settings. This paper describes the evaluation of the HPSISN program, including the evaluation model, key study question, findings and lessons learned. The HPSISN evaluation was designed to assess the effectiveness of service learning as a pedagogy in health professions education and describe the impact of service learning activities through university-community partnerships. The evaluation model was built upon a case study approach first developed for assessment of service learning courses at Portland State University and honors the participants\u27 commitment to mutually beneficial community partnerships. The findings illustrate the implications of service learning in the health professions and the lessons learned for education and evaluation

    Practice-based competencies for accreditation of and training in graduate programs in genetic counseling

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    In January 1996, the American Board of Genetic Counseling (ABGC) adopted 27 practice-based competencies as a standard for assessing the training of graduate students in genetic counseling. These competencies were identified and refined through a collective, narrative process that took place from January through November 1994, and included directors of graduate programs in genetic counseling, ABGC board members and expert consultants. These competencies now form the basis of the document ā€œRequirements for Graduate Programs in Genetic Counseling Seeking Accreditation by the American Board of Genetic Counselingā€ (American Board of Genetic Counseling, 1996). The competencies are organized into four domains and are presented and discussed in this article.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44929/1/10897_2005_Article_BF01408656.pd

    Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

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    The mammalian target of rapamycin (mTOR) regulates cell growth and survival by integrating nutrient and hormonal signals. These signaling functions are distributed between at least two distinct mTOR protein complexes: mTORC1 and mTORC2. mTORC1 is sensitive to the selective inhibitor rapamycin and activated by growth factor stimulation via the canonical phosphoinositide 3-kinase (PI3K)ā†’Aktā†’mTOR pathway. Activated mTORC1 kinase up-regulates protein synthesis by phosphorylating key regulators of mRNA translation. By contrast, mTORC2 is resistant to rapamycin. Genetic studies have suggested that mTORC2 may phosphorylate Akt at S473, one of two phosphorylation sites required for Akt activation; this has been controversial, in part because RNA interference and gene knockouts produce distinct Akt phospho-isoforms. The central role of mTOR in controlling key cellular growth and survival pathways has sparked interest in discovering mTOR inhibitors that bind to the ATP site and therefore target both mTORC2 and mTORC1. We investigated mTOR signaling in cells and animals with two novel and specific mTOR kinase domain inhibitors (TORKinibs). Unlike rapamycin, these TORKinibs (PP242 and PP30) inhibit mTORC2, and we use them to show that pharmacological inhibition of mTOR blocks the phosphorylation of Akt at S473 and prevents its full activation. Furthermore, we show that TORKinibs inhibit proliferation of primary cells more completely than rapamycin. Surprisingly, we find that mTORC2 is not the basis for this enhanced activity, and we show that the TORKinib PP242 is a more effective mTORC1 inhibitor than rapamycin. Importantly, at the molecular level, PP242 inhibits cap-dependent translation under conditions in which rapamycin has no effect. Our findings identify new functional features of mTORC1 that are resistant to rapamycin but are effectively targeted by TORKinibs. These potent new pharmacological agents complement rapamycin in the study of mTOR and its role in normal physiology and human disease

    Part 2: Preparing Entry-Level Occupational and Physical Therapy Students to Promote Healthy Lifestyles Emphasizing Healthy Eating with Individuals with Disabilities

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    Rehabilitation professionals including occupational therapists (OT) and physical therapists (PT) are increasingly called upon to incorporate health promotion of lifestyle behaviors including physical activity and healthy eating into routine clinical care. While OTs and PTs may be comfortable promoting activity-related behaviors, many are less comfortable with nutrition behaviors. To address entry-level OT and PT studentsā€™ perceived discomfort with discussing diet-related behaviors, faculty developed a healthy eating module for students to use during a community-based service learning program. The purpose of this paper is to describe the formative evaluation process of developing the healthy eating module, and to discuss results of a pilot trial of this module. The formative assessment of the healthy eating module consisted of four steps: focus groups with students, key informant interviews with community partners, expert panel round table, and expert panel review of materials. Students (n=117) completed questionnaires at the end of the service learning program to assess how much they used the new resources, and how useful they found the resources. The final healthy eating module consisted of an on-line training session and a healthy eating toolkit, including resources for assessments, treatment activities and additional nutrition information. Mann-Whitney U tests indicated that students who reported high use of materials found the resources significantly more helpful than those students who reported low use (

    Part 1: Preparing Entry-Level Occupational Therapy and Physical Therapy Students to Promote Health and Wellbeing with Individuals with Disabilities

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    To address accreditation standards for health and wellbeing within entry-level occupational therapy (OT) and physical therapy (PT) programs, the OT, PT, and Human Studies Departments at the University of Alabama at Birmingham (UAB) collaborated with community partners to conduct an interdisciplinary service learning activity based on the I Can Do It, You Can Do It Program (ICDI). This program is a structured community health program where individuals without disabilities are partnered with individuals with disabilities to enhance physical activity, healthy eating, and community participation. The purpose of this paper is to describe a formative evaluation of ICDI at UAB, and to discuss revisions to the program made as a result of the evaluation. Faculty used a qualitative design to collect feedback on perceived benefits and challenges of the program. Focus groups were conducted with students who completed the program, and key informant interviews were conducted with site coordinators from each of the three partnering community sites. Two themes emerged from student focus groups: (1) Program benefits, with sub-themes of hands-on application and interaction, and (2) Challenges with suggestions for change, with sub-themes of preparation, communication, and expectations. Four themes emerged from key informant interviews: (1) Students, (2) Logistics, (3) Program benefits, and (4) Transference. Results of this evaluation led to a number of revisions for the 2016 cohort. Future evaluations will include objective measures of change in student knowledge over time, as well as health and behavioral outcomes of community members who participated in the ICDI program at UAB

    Young peopleā€™s priorities for the self-management of distress after stoma surgery due to inflammatory bowel disease: a consensus study using online nominal group technique

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    Abstract Introduction: The aim of this study was to gain consensus among young people with a stoma due to inflammatory bowel disease (IBD) on the priorities for the content of an intervention for the self-management of stoma-related distress. The current identification and management of distress in young people with a stoma is often sub-optimal in clinical settings and there is a need for improved support resources.Methods: Two consensus group meetings were carried out via online video conferencing, using Nominal Group Technique. Participants generated, rated on a Likert scale and discussed, topics for inclusion in a future self-management intervention.Results: Nineteen young people, aged 19-33, with a stoma due to IBD took part in one of two group meetings. Participants were located across England, Scotland, and Northern Ireland. Twenty-nine topics were generated by participants, seven of which reached consensus of &gt;80%, that is, a mean of &gt;5.6 on a 7-point Likert scale. These were: receiving advice from young people with lived experience of stoma surgery; advice on/ addressing concerns about romantic relationships, sex and intimacy; information about fertility and pregnancy related to stoma surgery; stoma ā€˜hacksā€™, e.g. useful everyday tips regarding clothing, making bag changes easier etc.; reflecting on and recognising own emotional response to surgery; tips on managing the stoma during the night; and processing trauma related to the illness and surgery journey.Conclusions: Findings extend previous research on young peopleā€™s experiences of stoma surgery, by generating consensus on young peoplesā€™ priorities for managing distress related to surgery and living with a stoma. These priorities include topics not previously reported in the literature, including the need for information about fertility and pregnancy. Findings will inform the development of a self-management resource for young people with an IBD stoma and have relevance for the clinical management of stoma-related distress in this population.<br/

    Transmission of methicillin-resistant Staphylococcus aureus in long-term care facilities and their related healthcare networks.

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    BACKGROUND: Long-term care facilities (LTCF) are potential reservoirs for methicillin-resistant Staphylococcus aureus (MRSA), control of which may reduce MRSA transmission and infection elsewhere in the healthcare system. Whole-genome sequencing (WGS) has been used successfully to understand MRSA epidemiology and transmission in hospitals and has the potential to identify transmission between these and LTCF. METHODS: Two prospective observational studies of MRSA carriage were conducted in LTCF in England and Ireland. MRSA isolates were whole-genome sequenced and analyzed using established methods. Genomic data were available for MRSA isolated in the local healthcare systems (isolates submitted by hospitals and general practitioners). RESULTS: We sequenced a total of 181 MRSA isolates from the two study sites. The majority of MRSA were multilocus sequence type (ST)22. WGS identified one likely transmission event between residents in the English LTCF and three putative transmission events in the Irish LTCF. WGS also identified closely related isolates present in colonized Irish residents and their immediate environment. Based on phylogenetic reconstruction, closely related MRSA clades were identified between the LTCF and their healthcare referral network, together with putative MRSA acquisition by LTCF residents during hospital admission. CONCLUSIONS: These data confirm that MRSA is transmitted between residents of LTCF and is both acquired and transmitted to others in referral hospitals and beyond. Our data present compelling evidence for the importance of environmental contamination in MRSA transmission, reinforcing the importance of environmental cleaning. The use of WGS in this study highlights the need to consider infection control in hospitals and community healthcare facilities as a continuum.UKCRC Translational Infection Research (TIR) Initiative, Medical Research Council (Grant ID: G1000803), Biotechnology and Biological Sciences Research Council, National Institute for Health Research, Chief Scientist Office of the Scottish Government Health Directorate, Hospital Infection Society (Major Research Grant), Wellcome Trust (Grant ID: 098051), Academy of Medical Sciences, Health Foundation, National Institute for Health Research Cambridge Biomedical Research Centr

    The Grizzly, September 20, 1985

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    Forum Season Opens with Summit Diplomacy ā€¢ The Fields Are Coming ā€¢ Zeta Chi Escapes Suspension ā€¢ Lack of Water ā€¢ The Water Warden is Watching You ā€¢ Intramural Squeeze ā€¢ What\u27s Your Opinion? ā€¢ Japanese Now Available ā€¢ Prof Profile: Perreten Leads the List ā€¢ Dominic O\u27Brien Joins the Education Team ā€¢ Album Review: Squeeze Producing the Same Old Sound ā€¢ Jamison Appointed to Library Director ā€¢ Football Team Stretches for New Goals ā€¢ Women\u27s Field Hockey Climbing the Ladder! ā€¢ Volleyball Team Has Promise ā€¢ The Harriers are Off ā€¢ Bears Win Ugly ā€¢ More Talk About South Africa ā€¢ New Forum Force ā€¢ Whiteley: A Model of Desire and Determination ā€¢New Security Column ā€¢ Grant Me Thishttps://digitalcommons.ursinus.edu/grizzlynews/1144/thumbnail.jp

    The Grizzly, November 22, 1985

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    From Damp to Bone Dry? ā€¢ UCFL Takes to the Air: Or Visa Versa ā€¢ It\u27s all Greek to me ā€¢ The Descent on the Skunks of Ursinus ā€¢ Editorial: Yale Conference a Learning Experience ā€¢ Letter: Munchies Mandate ā€¢ Who\u27s Who Honors Ursinus ā€¢ How to Deal with Terrorists? ā€¢ Two Truman Scholars ā€¢ In Search of Success: Marivi Relova Brings Good Things to GE ā€¢ Communication a Must ā€¢ Bears Bounce Dickinson ā€¢ Booters Find Cold Times in New Hampshire ā€¢ Soccer Seniors Will be Missed ā€¢ Coach B. is Back ā€¢ Lady Bears Hope to Improve Behind Letuakas ā€¢ Season Tips Off Tonight ā€¢ Gymnasts Spring into Season ā€¢ Alercio Faces J Board ā€¢ Myrin Stacks Up ā€¢ Fields Should be Ready in Spring ā€¢ Immersion as Opposed to Voyeurism in Summer Study in France ā€¢ Smokeless Tobacco Still Burns ā€¢ Women\u27s Studies Added to Goal No. 9 ā€¢ Eating Healthy at College Essential ā€¢ Open Dialogs: Middle Class on Welfare?; Mercy Killing as a Solution; Birth Defects Popular With Geneticists ā€¢ Ursinus College: The Marriage Factoryhttps://digitalcommons.ursinus.edu/grizzlynews/1153/thumbnail.jp
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