4 research outputs found

    Un análisis de tendencia temporal (2012-2021)

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    Funding Information: Funding Source: The present work was carried out with the support of the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) – Finance Code 001. Publisher Copyright: © 2023, Sociedad Chilena de Nutricion Bromatologia y Toxilogica. All rights reserved.The present study aimed to analyze trends in the prevalence of overweight and obesity in Primary Health Care users in Piauí between 2012 and 2021. We conducted an ecological study with data from the Food and Nutrition Surveillance System. Overweight and obesity were classified as recommended by the World Health Organization. A linear regression was performed to estimate the trend in the prevalence of overweight and obesity. There was an increase in the prevalence of overweight and obesity in Piauí in the period studied in all age groups and in both sexes. However, the growth trend was stationary for overweight in males in the age groups of children and adolescents, and for obesity in both sexes amongst 0-9-year-olds. The study showed an increase in the prevalence of overweight and obesity between 2012 and 2021 in all age groups and in both sexes. However, the growth trend was stationary in some.publishersversionpublishe

    Zinc and Oxidative Stress: Current Mechanisms

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    Oxidative stress is a metabolic dysfunction that favors the oxidation of biomolecules, contributing to the oxidative damage of cells and tissues. This consequently contributes to the development of several chronic diseases. In particular, zinc is one of the most relevant minerals to human health, because of its antioxidant properties. This review aims to provide updated information about the mechanisms involved in the protective role of zinc against oxidative stress. Zinc acts as a co-factor for important enzymes involved in the proper functioning of the antioxidant defense system. In addition, zinc protects cells against oxidative damage, acts in the stabilization of membranes and inhibits the enzyme nicotinamide adenine dinucleotide phosphate oxidase (NADPH-Oxidase). Zinc also induces the synthesis of metallothioneins, which are proteins effective in reducing hydroxyl radicals and sequestering reactive oxygen species (ROS) produced in stressful situations, such as in type 2 diabetes, obesity and cancer. Literature provides strong evidence for the role of zinc in the protection against oxidative stress in several diseases
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