107 research outputs found
Validity And Reliability Of A Self-efficacy Expectancy Scale For Adherence To Antiretroviral Therapy For Parents And Carers Of Children And Adolescents With Hiv/aids [validação E Reprodutibilidade De Uma Escala De Auto-eficåcia Para Adesão Ao Tratamento Anti-retroviral Em Pais Ou Cuidadores De Crianças E Adolescentes Vivendo Com Hiv/aids]
Objective: To validate and evaluate the reproducibility of a self-efficacy (SE) scale for adherence to antiretroviral therapy in children and adolescents with HIV/AIDS, taking into account the perspective of parents/guardians. Methods: The study was carried out at the Hospital-Dia, Centro de ReferĂȘncia e Treinamento em DST/AIDS (CRT/SP), in SĂŁo Paulo, Brazil. The parents/guardians of 54 children and adolescents aged 6 months to 20 years were interviewed during routine consultations at our service. Data on SE were collected using the Self-Efficacy for Following Anti-Retroviral Prescription Scale, and SE scores were calculated in two different ways: factor analysis and a predefined formula. The scale's internal consistency was verified using Cronbach's α coefficient. Validity was tested by comparing the mean scores of a group of patients who did adhere to antiretroviral treatment with those of a group that did not (Mann-Whitney test) and by calculating the Spearman correlation coefficient for agreement between scores and clinical parameters. Reproducibility was verified using the Wilcoxon test, intraclass correlation coefficients (ricc) and Bland-Altman plots. Results: The SE scale demonstrated good internal consistency (α = 0.87) and good reproducibility (r icc = 0.69 and r icc = 0.75). In terms of validity, the SE scale was capable of differentiating adherent patients from those who did not adhere to their antiretroviral treatment (p = 0.002) and exhibited a significant correlation with CD4 counts (r = 0.28; p = 0.04). Conclusions: The SE scale can be used to assess adherence to antiretroviral therapy in children and adolescents with HIV/AIDS, taking into account the perspective of parents/carers. Copyright © 2008 by Sociedade Brasileira de Pediatria.8414146Matida, L.H., da Silva, M.H., Tayra, A., Succi, R.C., Gianna, M.C., Gonçalves, A., Prevention of mother-to-child transmission of HIV in SĂŁo Paulo State, Brazil: An update (2005) AIDS, 19 (SUPPL. 4), pp. S37-S41Gibb, D.M., Goodall, R.L., Giacomet, V., McGee, L., Compagnucci, A., Lyall, H., Paediatric European Network for Treatment of Aids Steering Committee. Adherence to prescribed antiretroviral therapy in human immunodeficiency virus-infected children in the PENTA 5 trial (2003) Pediatr Infect Dis J, 22, pp. 56-62Pluciennik, A.M., (2003) TransmissĂŁo materno infantil do vĂrus da imunodeficiĂȘncia humana adquirida: Quanto custa nĂŁo prevenir [tese], , SĂŁo Paulo: Faculdade de SaĂșde PĂșblica da USP;Dyke, R.B.V., Lee, S., Johnson, G.M., Wiznia, A., Mohan, K., Stanley, K., Reported adherence as a determinant of response to highly active antiretroviral therapy in children who have human immunodeficiency virus infection (2002) Pediatrics, 109 (4), pp. 1-7Starace, F., Massa, A., Amico, K.R., Fisher, J.D., Adherence to antiretroviral therapy: An empirical test of the information-motivation-behavioral skills model (2006) Health Psychol, 25, pp. 153-162Shah, C.A., Adherence to high activity antiretroviral therapy (HAART) in pediatric patients infected with HIV: Issues and interventions (2007) Indian J Pediatr, 74, pp. 55-60Leite, J.C., Drachler, M.L., Centeno, M.O., Pinheiro, C.A., Silveira, V.L., Desenvolvimento de uma escala de auto-eficĂĄcia para adesĂŁo ao tratamento anti-retroviral. (2002) Psicol Reflex Crit, 15, pp. 121-133Bandura, A., Self-efficacy: Toward a unifying theory of behavioral change (1977) Psychol Rev, 84, pp. 191-215Gortmaker SL, Lenderking WR, Clark C, Lee S, Fowler MG, Oleske JMThe ACTG 219 Team. Development and use of a pediatric quality of life questionnaire in AIDS clinical trials: reliability and validity of the general health assessment for children. In: Drotar D. Measuring health-related quality of life in children and adolescents: implications for research and practice. Mahwah, NJ: Lawrence Erlbaum Associates1998. p. 219-35Eiser, C., Morse, R., Quality-of-life measures in chronic diseases of childhood (2001) Health Technol Assess, 5, pp. 1-95Streiner, D.L., Norman, G.R., (2003) Health measurement scales: A practical guide to their development and use, , 3rd ed. Oxford: Oxford University Press;Drotar D, Levi R. Critical issues and needs in health-related quality of life assessment of children and adolescents with chronic health condition. In: Drotar D. Measuring health-related quality of life in children and adolescents: implications for research and practice. Mahwah, NJ: Lawrence Erlbaum Associates1998. p. 3-2
Supergravity p-branes revisited: extra parameters, uniqueness, and topological censorship
We perform a complete integration of the Einstein-dilaton-antisymmetric form
action describing black p-branes in arbitrary dimensions assuming the
transverse space to be homogeneous and possessing spherical, toroidal or
hyperbolic topology. The generic solution contains eight parameters satisfying
one constraint. Asymptotically flat solutions form a five-parametric subspace,
while conditions of regularity of the non-degenerate event horizon further
restrict this number to three, which can be related to the mass and the charge
densities and the asymptotic value of the dilaton. In the case of a degenerate
horizon, this number is reduced by one. Our derivation constitutes a
constructive proof of the uniqueness theorem for -branes with the
homogeneous transverse space. No asymptotically flat solutions with toroidal or
hyperbolic transverse space within the considered class are shown to exist,
which result can be viewed as a demonstration of the topological censorship for
p-branes. From our considerations it follows, in particular, that some
previously discussed p-brane-like solutions with extra parameters do not
satisfy the standard conditions of asymptotic flatness and absence of naked
singularities. We also explore the same system in presence of a cosmological
constant, and derive a complete analytic solution for higher-dimensional
charged topological black holes, thus proving their uniqueness.Comment: Revtex4, no figure
Effective Lagrangian for and Vertices in the mSUGRA model
Complete expressions of the and vertices are
derived in the framework of supersymmetry with minimal flavor violation. With
the minimal supergravity (mSUGRA) model, a numerical analysis of the
supersymmetric contributions to the Wilson Coefficients at the weak scale is
presented.Comment: 12 pages + 7 ps figures, Late
Softening the Supersymmetric Flavor Problem in Orbifold GUTs
The infra-red attractive force of the bulk gauge interactions is applied to
soften the supersymmetric flavor problem in the orbifold SU(5) GUT of Kawamura.
Then this force aligns in the infra-red regime the soft supersymmetry breaking
terms out of their anarchical disorder at a fundamental scale, in such a way
that flavor-changing neutral currents as well as dangerous CP-violating phases
are suppressed at low energies. It is found that this dynamical alignment is
sufficiently good compared with the current experimental bounds, as long as the
diagonalization matrices of the Yukawa couplings are CKM-like.Comment: 15 pages,4 figure
Status of the superworld: from theory to experiment
Review to appear in Progress in Particle and Nuclear Physics. Contents:
{1}Introduction}{1} {2}High precision LEP data and convergence of couplings:
physics is not Euclidean geometry}{2} {3}Interconnections between the measured
quantities due to Unification}{7} {4}The origin of and why it should
be abandoned: masses and spectra are needed}{13} {5}The new step forward:
Supergravity}{21} {6}The SU(5) Supergravity Model}{22} {7}SU(5)xU(1)
Supergravity}{32} {8}Detailed calculations for the Tevatron}{47} {9}Detailed
calculations for LEP}{48} {10}Detailed calculations for HERA}{53} {11}Detailed
calculations for Underground Labs and Underwater facilities}{55} {12}Detailed
calculations for indirect experimental detection}{65} {13}The problem of mass
and }{73} {14}Conclusions}{77}Comment: 90 pages, 41 figures (not included), latex. Send requests for hard
copies to "[email protected]". CERN-TH.7136/94, CTP-TAMU-80/9
Finite Theories and the SUSY Flavor Problem
We study a finite SU(5) grand unified model based on the non-Abelian discrete
symmetry A_4. This model leads to the democratic structure of the mass matrices
for the quarks and leptons. In the soft supersymmetry breaking sector, the
scalar trilinear couplings are aligned and the soft scalar masses are
degenerate, thus solving the SUSY flavor problem.Comment: 17 pages, LaTeX, 1 figur
Exploring flavor structure of supersymmetry breaking from rare B decays and unitarity triangle
We study effects of supersymmetric particles in various rare B decay
processes as well as in the unitarity triangle analysis. We consider three
different supersymmetric models, the minimal supergravity, SU(5) SUSY GUT with
right-handed neutrinos, and the minimal supersymmetric standard model with U(2)
flavor symmetry. In the SU(5) SUSY GUT with right-handed neutrinos, we consider
two cases of the mass matrix of the right-handed neutrinos. We calculate direct
and mixing-induced CP asymmetries in the b to s gamma decay and CP asymmetry in
B_d to phi K_S as well as the B_s--anti-B_s mixing amplitude for the unitarity
triangle analysis in these models. We show that large deviations are possible
for the SU(5) SUSY GUT and the U(2) model. The pattern and correlations of
deviations from the standard model will be useful to discriminate the different
SUSY models in future B experiments.Comment: revtex4, 36 pages, 10 figure
All-sky search for long-duration gravitational wave transients with initial LIGO
We present the results of a search for long-duration gravitational wave transients in two sets of data collected by the LIGO Hanford and LIGO Livingston detectors between November 5, 2005 and September 30, 2007, and July 7, 2009 and October 20, 2010, with a total observational time of 283.0 days and 132.9 days, respectively. The search targets gravitational wave transients of duration 10-500 s in a frequency band of 40-1000 Hz, with minimal assumptions about the signal waveform, polarization, source direction, or time of occurrence. All candidate triggers were consistent with the expected background; as a result we set 90% confidence upper limits on the rate of long-duration gravitational wave transients for different types of gravitational wave signals. For signals from black hole accretion disk instabilities, we set upper limits on the source rate density between 3.4Ă10-5 and 9.4Ă10-4 Mpc-3 yr-1 at 90% confidence. These are the first results from an all-sky search for unmodeled long-duration transient gravitational waves. © 2016 American Physical Society
All-sky search for long-duration gravitational wave transients with initial LIGO
We present the results of a search for long-duration gravitational wave transients in two sets of data collected by the LIGO Hanford and LIGO Livingston detectors between November 5, 2005 and September 30, 2007, and July 7, 2009 and October 20, 2010, with a total observational time of 283.0 days and 132.9 days, respectively. The search targets gravitational wave transients of duration 10-500 s in a frequency band of 40-1000 Hz, with minimal assumptions about the signal waveform, polarization, source direction, or time of occurrence. All candidate triggers were consistent with the expected background; as a result we set 90% confidence upper limits on the rate of long-duration gravitational wave transients for different types of gravitational wave signals. For signals from black hole accretion disk instabilities, we set upper limits on the source rate density between 3.4Ă10-5 and 9.4Ă10-4 Mpc-3 yr-1 at 90% confidence. These are the first results from an all-sky search for unmodeled long-duration transient gravitational waves. © 2016 American Physical Society
Search for Tensor, Vector, and Scalar Polarizations in the Stochastic Gravitational-Wave Background
The detection of gravitational waves with Advanced LIGO and Advanced Virgo has enabled novel tests of general relativity, including direct study of the polarization of gravitational waves. While general relativity allows for only two tensor gravitational-wave polarizations, general metric theories can additionally predict two vector and two scalar polarizations. The polarization of gravitational waves is encoded in the spectral shape of the stochastic gravitational-wave background, formed by the superposition of cosmological and individually unresolved astrophysical sources. Using data recorded by Advanced LIGO during its first observing run, we search for a stochastic background of generically polarized gravitational waves. We find no evidence for a background of any polarization, and place the first direct bounds on the contributions of vector and scalar polarizations to the stochastic background. Under log-uniform priors for the energy in each polarization, we limit the energy densities of tensor, vector, and scalar modes at 95% credibility to Ω0T<5.58Ă10-8, Ω0V<6.35Ă10-8, and Ω0S<1.08Ă10-7 at a reference frequency f0=25 Hz. © 2018 American Physical Society
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