35 research outputs found
Numerical modelling of the cavitation damage in the conrod big end bearing of a high-performance internal combustion engine
In this contribution a complementarity formulation for the solution of the elastohydrodynamic problem in the presence of cavitation is employed to investigate the tribological behaviour of the conrod big end bearing in a high-performance internal combustion engine. The continuous effort towards higher engine efficiencies, poses new challenges related to the increased specific loads to which engine components are subjected. In particular, the connecting rod big end bearing is subjected to both high loads and high relative velocity of the mating surfaces. Therefore, its tribological behaviour plays a crucial role. In fact, on one side, possible asperity contact pressures can produce wear of the interested components, and on the other side, a parallel possible cavitation of the lubricant can additionally damage the mating interfaces. Unfortunately for quantifying the cavitation damage, a universally established theory does not exist, even if it is well accepted that it is related to the sudden rapid implosion of the vapour bubbles near the surface. The precise investigation of this damage mechanism is usually neglected in big end bearing analysis since the implosion of the bubbles is difficult to quantify and it is not a standard output of any commercial software. Thus, in this work, a quantitative index previously proposed is reviewed and adopted to quantify the cavitation damage in a connecting rod big end bearing
Crystallization of stable doped mannitol polymorphs and in vitro assessment of their safety as carriers for lung delivery
Bowel preparation for elective colorectal resection: multi-treatment machine learning analysis on 6241 cases from a prospective Italian cohort
background current evidence concerning bowel preparation before elective colorectal surgery is still controversial. this study aimed to compare the incidence of anastomotic leakage (AL), surgical site infections (SSIs), and overall morbidity (any adverse event, OM) after elective colorectal surgery using four different types of bowel preparation. methods a prospective database gathered among 78 Italian surgical centers in two prospective studies, including 6241 patients who underwent elective colorectal resection with anastomosis for malignant or benign disease, was re-analyzed through a multi-treatment machine-learning model considering no bowel preparation (NBP; No. = 3742; 60.0%) as the reference treatment arm, compared to oral antibiotics alone (oA; No. = 406; 6.5%), mechanical bowel preparation alone (MBP; No. = 1486; 23.8%), or in combination with oAB (MoABP; No. = 607; 9.7%). twenty covariates related to biometric data, surgical procedures, perioperative management, and hospital/center data potentially affecting outcomes were included and balanced into the model. the primary endpoints were AL, SSIs, and OM. all the results were reported as odds ratio (OR) with 95% confidence intervals (95% CI). results compared to NBP, MBP showed significantly higher AL risk (OR 1.82; 95% CI 1.23-2.71; p = .003) and OM risk (OR 1.38; 95% CI 1.10-1.72; p = .005), no significant differences for all the endpoints were recorded in the oA group, whereas MoABP showed a significantly reduced SSI risk (OR 0.45; 95% CI 0.25-0.79; p = .008). conclusions MoABP significantly reduced the SSI risk after elective colorectal surgery, therefore representing a valid alternative to NBP
Abdominal drainage after elective colorectal surgery: propensity score-matched retrospective analysis of an Italian cohort
background: In italy, surgeons continue to drain the abdominal cavity in more than 50 per cent of patients after colorectal resection. the aim of this study was to evaluate the impact of abdominal drain placement on early adverse events in patients undergoing elective colorectal surgery. methods: a database was retrospectively analysed through a 1:1 propensity score-matching model including 21 covariates. the primary endpoint was the postoperative duration of stay, and the secondary endpoints were surgical site infections, infectious morbidity rate defined as surgical site infections plus pulmonary infections plus urinary infections, anastomotic leakage, overall morbidity rate, major morbidity rate, reoperation and mortality rates. the results of multiple logistic regression analyses were presented as odds ratios (OR) and 95 per cent c.i. results: a total of 6157 patients were analysed to produce two well-balanced groups of 1802 patients: group (A), no abdominal drain(s) and group (B), abdominal drain(s). group a versus group B showed a significantly lower risk of postoperative duration of stay >6 days (OR 0.60; 95 per cent c.i. 0.51-0.70; P < 0.001). a mean postoperative duration of stay difference of 0.86 days was detected between groups. no difference was recorded between the two groups for all the other endpoints. conclusion: this study confirms that placement of abdominal drain(s) after elective colorectal surgery is associated with a non-clinically significant longer (0.86 days) postoperative duration of stay but has no impact on any other secondary outcomes, confirming that abdominal drains should not be used routinely in colorectal surgery
High resolution solid state NMR spectroscopy of foods
The general principles of the application of high
resolution solid-state NMR spectroscopy in food
science are presented in a simplified way to become
easily familial to the reader. Some preliminary
introductory notes about the chemical properties of
the foods in the solid-state are also reported. The
principal applications have been reviewed mainly
focussing the potentiality of these investigations,
which are routine tools for resolving technological
problems in food industry. Some selected examples
of application of high resolution solid-state NM
High resolution solid state NMR spectroscopy of foods
The general principles of the application of high
resolution solid-state NMR spectroscopy in food
science are presented in a simplified way to become
easily familial to the reader. Some preliminary
introductory notes about the chemical properties of
the foods in the solid-state are also reported. The
principal applications have been reviewed mainly
focussing the potentiality of these investigations,
which are routine tools for resolving technological
problems in food industry. Some selected examples
of application of high resolution solid-state NM
Did colonization matter for growth? An empirical exploration into the historical causes of Africa's underdevelopment
We investigate the impact of 20th--century European colonization
on growth in Africa. We find that in the 1960--88 period growth has been
faster for dependencies than for colonies; for British and French
colonies than for Portuguese, Belgian and Italian ones; and for countries
with less economic penetration during the colonial period. On average,
African growth accelerates after decolonization. Proxies for colonial
heritage add explanatory power to growth regressions and make indicators
for human capital, political and ethnic instability lose significance.
Colonial variables capture the same effects of a sub--Saharan dummy and
reduce its significance when jointly included in a cross sectional
regression with 98 countries
Did colonization matter for growth?: An empirical exploration into the historical causes of Africa's underdevelopment
Did colonization matter for growth? An empirical exploration into the historical causes of Africa's underdevelopment
We investigate the impact of 20th--century European colonizationon growth in Africa. We find that in the 1960--88 period growth has beenfaster for dependencies than for colonies; for British and Frenchcolonies than for Portuguese, Belgian and Italian ones; and for countrieswith less economic penetration during the colonial period. On average,African growth accelerates after decolonization. Proxies for colonialheritage add explanatory power to growth regressions and make indicatorsfor human capital, political and ethnic instability lose significance.Colonial variables capture the same effects of a sub--Saharan dummy andreduce its significance when jointly included in a cross sectionalregression with 98 countries
Solid-state 13C CP MAS NMR spectroscopy of mushrooms gives directly the ratio between proteins and polysaccharides
The solid-state 13C CP MAS NMR technique has the potential of monitoring the chemical composition in the solid state of an intact food sample. This property has been utilized to study mushrooms of different species (Pleurotus ostreatus, Pleurotus eryngii, Pleurotus pulmunarius, and Lentinula edodes), already characterized by chemical analyses for protein and dietary fiber components. Solidstate 13C CP MAS NMR spectroscopy reveals a large difference in the ratio between the glucidic and the proteic resonances probably depending on the mushroom species. An accurate inspection by model compounds and suitable mixtures of proteins and saccharides gives a methodology to interpret these experimental data. A good correlation (R2 = 0.93; R2 = 0.81) has been obtained by comparing the NMR data with the results of the chemical analyses. The results suggest the possibility to perform a taxonomic study and/or a nutritional study on the basis of the ratio between protein and polysaccharide levels determined by NMR or chemical methodologies