Person or place? A contextual event-history analysis of homicide victimization risk

This study is a contextual event history analysis of the risk of homicide victimization in the United States from 1986 to 2002. Although the majority of research on homicide deals with how community factors influence homicide rates, a much less studied aspect of homicide victimization deals with the influence of individual factors on homicide victimization risk. This study examines the influence of contextual-level measures of social disorganization on the risk of homicide victimization and focuses specifically on how the effects of these measures change once individual-level characteristics are considered in the models. Grounded in social disorganization theory, this study includes contextual-level predictors of disadvantage, including measures representative of resource deprivation, urbanness, and housing instability. Lifestyle theory suggests that a person’s individual attributes may compel that person to behave in certain ways that may work to either increase or decrease their risk of being the victim of a crime, and may also reduce or diminish the effects of the social structure on their risk of victimization. This study, using National Health Interview Survey (NHIS) data matched with National Death Index (NDI) data, examines the intersection of these ideas and seeks to explain how community context influences one’s chance of being a homicide victim and especially on how individual attributes alter the relationship between community context and homicide victimization. The findings of this research indicate that individuals living in areas with high concentrations of disadvantage, such as resource deprivation, urbanization, and housing instability experience increased risk of being the victim of a homicide. However, a person’s individual traits, particularly age, race, and sex do, in fact, greatly reduce the criminogenic consequences of both resource deprivation and housing instability on their risk of being killed by a homicide. However, regardless of a person’s individual attributes, living in an area with high levels of urbanization have three times greater odds of being killed by a homicide, compared to person’s living in MSAs with less urbanization. In this study, urbanization is measured using an index obtained from a principal components analysis that contains measures of population size, population density, and two measures of racial/ethnic heterogeneity

La formation des intervenants

Puisque le sida constitue un problème nouveau et grave de santé publique et que les professionnels sont peu préparés pour y faire face, l'élaboration d'un programme-cadre de formation s'avère importante. La première partie du texte décrit succinctement les objectifs, contenus et approches pédagogiques d'un tel programme. Dans ce cadre général, deux applications concrètes sont ici décrites : la sensibilisation d'intervenants à la problématique de l'infection VIH et du sida, et la formation continue de professionnels impliqués directement dans la distribution des services offerts à la clientèle touchée par la problématique

Laser generation of Rayleigh and Lamb waves for ultrasonic nondestructive testing

Laser ultrasonics has been the focus of several research efforts over the last two decades. The main advantage of the technique is its noncontact nature which alleviates the problem of sensor coupling inherent in conventional techniques. However, laser ultrasonics has some limitations When operated in the thermoelastic regime, where no damage is inflicted on the surface of the specimen, the signal-to-noise ratio (SNR) is very small, particularly when compared with conventional piezoelectric generation.[1] Several authors have proposed increasing the SNR by producing a source with spatial periodicity designed to enhance a particular wavelength. Royer and Dieulasaint [2] have used a periodic mask, Wagner et al [3] have used a lenticular array, Vogel [4] and Berthelot and Jarzynski [5] have used an array of optical fibers. Cielo et al. [6] increased the SNR by increasing the displacement by geometrical focusing. They detected the displacement of surface waves at the center of an anular source and demonstrated that it was 20 times greater than that of a spot source

Scots-Irish Women and the Southern Culture of Violence: The Influence of Scots-Irish Females on High Rates of Southern Violence

Prior research has documented a higher rate of violent crime within the South relative to other U.S. regions. Some scholars argue that higher rates of violence in the South are due to the lasting effect of the unique culture of the Scots-Irish immigrants that came into the U.S. in the mid-1700\u27s. Though there is a large body of literature examining the link between culture and violence in the South, an implicit assumption of this line of study is that the cultural effect occurs largely within the white male population in rural Southern areas. No study, to our knowledge, has extended this thesis to females. We address this omission in prior analyses by empirically testing the Southern Culture of Violence thesis using female arrest rates. Drawing on countylevel ancestry data from the 2000 Census and UCR Supplementary Homicide Report data, we estimate a series of negative binomial regression models. A conclusion and discussion of the results follow

Mechanical, Cardiorespiratory, and Muscular Oxygenation Responses to Sprint Interval Exercises Under Different Hypoxic Conditions in Healthy Moderately Trained Men.

Objective: The aim of this study was to determine the effects of sprint interval exercises (SIT) conducted under different conditions (hypoxia and blood flow restriction [BFR]) on mechanical, cardiorespiratory, and muscular O <sub>2</sub> extraction responses. Methods: For this purpose, 13 healthy moderately trained men completed five bouts of 30 s all-out exercises interspaced by 4 min resting periods with lower limb bilateral BFR at 60% of the femoral artery occlusive pressure (BFR <sub>60</sub> ) during the first 2 min of recovery, with gravity-induced BFR (pedaling in supine position; G-BFR), in a hypoxic chamber (FiO <sub>2</sub> ≈13%; HYP) or without additional stress (NOR). Peak and average power, time to achieve peak power, rating of perceived exertion (RPE), and a fatigue index (FI) were analyzed. Gas exchanges and muscular oxygenation were measured by metabolic cart and NIRS, respectively. Heart rate (HR) and peripheral oxygen saturation (SpO <sub>2</sub> ) were continuously recorded. Results: Regarding mechanical responses, peak and average power decreased after each sprint (p < 0.001) excepting between sprints four and five. Time to reach peak power increased between the three first sprints and sprint number five (p < 0.001). RPE increased throughout the exercises (p < 0.001). Of note, peak and average power, time to achieve peak power and RPE were lower in G-BFR (p < 0.001). Results also showed that SpO <sub>2</sub> decreased in the last sprints for all the conditions and was lower for HYP (p < 0.001). In addition, Δ[O <sub>2</sub> Hb] increased in the last two sprints (p < 0.001). Concerning cardiorespiratory parameters, BFR <sub>60</sub> application induced a decrease in gas exchange rates, which increased after its release compared to the other conditions (p < 0.001). Moreover, muscle blood concentration was higher for BFR <sub>60</sub> (p < 0.001). Importantly, average and peak oxygen consumption and muscular oxyhemoglobin availability during sprints decreased for HYP (p < 0.001). Finally, the tissue saturation index was lower in G-BFR. Conclusions: Thus, SIT associated with G-BFR displayed lower mechanical, cardiorespiratory responses, and skeletal muscle oxygenation than the other conditions. Exercise with BFR <sub>60</sub> promotes higher blood accumulation within working muscles, suggesting that BFR <sub>60</sub> may additionally affect cellular stress. In addition, HYP and G-BFR induced local hypoxia with higher levels for G-BFR when considering both exercise bouts and recovery periods

Ice Formation on Kaolinite: Insights from Molecular Dynamics Simulations

The formation of ice affects many aspects of our everyday life as well as technologies such as cryotherapy and cryopreservation. Foreign substances almost always aid water freezing through heterogeneous ice nucleation, but the molecular details of this process remain largely unknown. In fact, insight into the microscopic mechanism of ice formation on different substrates is difficult to obtain even via state-of-the-art experimental techniques. At the same time, atomistic simulations of heterogeneous ice nucleation frequently face extraordinary challenges due to the complexity of the water-substrate interaction and the long timescales that characterize nucleation events. Here, we have investigated several aspects of molecular dynamics simulations of heterogeneous ice nucleation considering as a prototypical ice nucleating material the clay mineral kaolinite, which is of relevance in atmospheric science. We show via seeded molecular dynamics simulations that ice nucleation on the hydroxylated (001) face of kaolinite proceeds exclusively via the formation of the hexagonal ice polytype. The critical nucleus size is two times smaller than that obtained for homogeneous nucleation at the same supercooling. Previous findings suggested that the flexibility of the kaolinite surface can alter the time scale for ice nucleation within molecular dynamics simulations. However, we here demonstrate that equally flexible (or non flexible) kaolinite surfaces can lead to very different outcomes in terms of ice formation, according to whether or not the surface relaxation of the clay is taken into account. We show that very small structural changes upon relaxation dramatically alter the ability of kaolinite to provide a template for the formation of a hexagonal overlayer of water molecules at the water-kaolinite interface, and that this relaxation therefore determines the nucleation ability of this mineral

On the pp-supports of a holonomic D\mathcal{D}-module

For a smooth variety $Y$ over a perfect field of positive characteristic, the sheaf $D_Y$ of crystalline differential operators on $Y$ (also called the sheaf of $PD$-differential operators) is known to be an Azumaya algebra over $T^*_{Y'},$ the cotangent space of the Frobenius twist $Y'$ of $Y.$ Thus to a sheaf of modules $M$ over $D_Y$ one can assign a closed subvariety of $T^*_{Y'},$ called the $p$-support, namely the support of $M$ seen as a sheaf on $T^*_{Y'}.$ We study here the family of $p$-supports assigned to the reductions modulo primes $p$ of a holonomic $\mathcal{D}$-module. We prove that the Azumaya algebra of differential operators splits on the regular locus of the $p$-support and that the $p$-support is a Lagrangian subvariety of the cotangent space, for $p$ large enough. The latter was conjectured by Kontsevich. Our approach also provides a new proof of the involutivity of the singular support of a holonomic $\mathcal{D}$-module, by reduction modulo $p.$Comment: The article has been rewritten with much improved exposition as well as some additional results, e.g. Corollary 6.3.1. This is the final version, accepted for publication in Inventiones Mathematica

In vivo time-lapse imaging of mitochondria in healthy and diseased peripheral myelin sheath

The myelin sheath that covers a large amount of neurons is critical for their homeostasis, and myelinating glia mitochondria have recently been shown to be essential for neuron survival. However morphological and physiological properties of these organelles remain elusive. Here we report a method to analyze mitochondrial dynamics and morphology in myelinating Schwann cells of living mice using viral transduction and time-lapse multiphoton microscopy. We describe the distribution, shape, size and dynamics of mitochondria in live cells. We also report mitochondrial alterations in Opa1(delTTAG) mutant mice cells at presymptomatic stages, suggesting that mitochondrial defects in myelin contribute to OPA1 related neuropathy and represent a biomarker for the disease

Removing the barrier to the calculation of activation energies: Diffusion coefficients and reorientation times in liquid water

See also: The Journal of Chemical Physics 145 (13), 134107 (2016). The following article appeared in Piskulich, Z. A., Mesele, O. O., & Thompson, W. H. (2017). Removing the barrier to the calculation of activation energies: Diffusion coefficients and reorientation times in liquid water. The Journal of Chemical Physics, 147(13), 134103. and may be found at https://aip.scitation.org/doi/10.1063/1.4997723.General approaches for directly calculating the temperature dependence of dynamical quantities from simulations at a single temperature are presented. The method is demonstrated for self-diffusion and OH reorientation in liquid water. For quantities which possess an activation energy, e.g., the diffusion coefficient and the reorientation time, the results from the direct calculation are in excellent agreement with those obtained from an Arrhenius plot. However, additional information is obtained, including the decomposition of the contributions to the activation energy. These results are discussed along with prospects for additional applications of the direct approach

The derivation of performance expressions for communication protocols from timed Petri net models

Petri Net models have been extended in a variety of ways and have been used to prove the correctness and evaluate the performance of communication protocols. Several extensions have been proposed to model time. This work uses a form of Timed Petri Nets and presents a technique for symbolically deriving expressions which describe system performance. Unlike past work on performance evaluation of Petri Nets which assumes a priori knowledge of specific time delays, the technique presented here applies to a wide range of time delays so long as the delays satisfy a set of timing constraints. The technique is demonstrated using a simple communication protocol