Bioakumulasi Logam Tembaga (Cu) Dan Kadmium (Cd) Pada Kerang Karawauw (Batissa violacea) Di Sungai Wosimi Teluk Wondama

Kerang Batissa violacea dikenal sebagai Kerang Karawauw merupakan salah satu sumber daya perairan Teluk Wondama yang dikonsumsi dan mempunyai nilai ekonomi. Peningkatan jumlah penduduk dan aktivitas pelayaran serta perikanan berdampak pada kualitas perairan disekitarnya. Penelitian ini bertujuan untuk mengetahui konsentrasi logam Cu dan Cd dalam air, sedimen, dan Kerang Karawauw (Batissa violacea) di Sungai Wosimi dan mengetahui tingkat bioakumulasi Kerang Karawauw (Batissa violacea) terhadap logam Cu dan Cd di sungai Wosimi. Metode pengambilan sampel Kerang Karawauw menggunakan metode random sampling, sampel air dan sedimen diambil pada lokasi yang sama dengan lokasi pengambilan sampel kerang. Kandungan logam Cu dan Cd dalam sampel air, kerang dan sedimen dianalisis menggunakan Atomic Absorbance Spectrofotometer (AAS). Konsentrasi logam Cu dalam air berkisar antara <0,0001 - 0.0094 mg/L, konsentrasi logam Cu dalam sedimen berkisar antara 2,60 - 29,74 mg/kg, konsentrasi logam Cu dalam kerang berkisar antara 9,0335 - 34,9200 mg/kg. Konsentrasi logam Cd dalam air berkisar antara <0,0001 - 0.0113 mg/L, konsentrasi logam Cd dalam sedimen berkisar antara <0,0001 -  6,54 mg/kg, sedangkan konsentrasi logam Cd dalam kerang adalah < 0,0001 mg/kg pada semua lokasi kajian. Nilai BAFo-w tertinggi untuk logam Cu terdapat pada lokasi IV (K2) sebesar 6020,48 tergolong tingkat akumulasi tinggi, sedangkan nilai BAFo-s tertinggi untuk logam Cu terdapat pada lokasi III (K2) sebesar 8,81 atau tergolong tingkat akumulasi rendah

POTENSI KITOSAN DARI LIMBAH CANGKANG UDANG Penaeus monodon ASAL BINTUNI SEBAGAI BIOSORBEN LIMBAH ORGANIK DAN LOGAM BERAT PADA LIMBAH CAIR PLTD MANOKWARI

The purpose of this research is to study the potency of chitosan synthesis of shrimp shells from Bintuni as a biosorbent of organic compound and heavy metal compound. The main procedure of chitosan synthesis is completed by insulating chitin from shrimp shells and then chitin is deacetilated to transform chitin to be chitosan. The wastewater were characterized to know the concentration of Total Organic Carbon (TOC), fat oil, and Zinc metal and studied the adsorption of each compound at 0,1; 0,5; 1; 2g dosage chitosan. Adsorption study result showed that chitosan can adsorb the fuel oil and Zinc metal which contained in wastewater. However, it was not adsorb the TOC compound. The yield of chitosan is 46,88%. Increasing the chitosan by up to 2 g resulted in the creasing of the adsorption effectiveness up to 99,09% for the fuel oil and 69,28% for Zinc. The maximum chitosan adsorption capacity accomplished at 0,1gram chitosan in 100 mL wastewater

Uji Aktivitas Antidiabetes Dengan Metode Penghambatan Enzim α-Glukosidase dan Karakterisasi Kandungan Senyawa Aktif pada Fraksi Metanol dan Kloroform Daun Lavetar (Wedelia biflora (L).DC) Asal Biak

Salah satu jenis tanaman yang dijadikan sebagai obat tradisional adalah tumbuhan Lavetar (W. biflora) yang di manfaatkan oleh masyarakat Biak sebagai obat untuk mengobati penyakit diabetes. Penemuan sumber penghambat α-glukosidase sangat bermanfaat dalam upaya pengembangan obat herbal yang lebih efektif bagi penderita diabetes. Penelitian ini bertujuan untuk menentukan aktivitas antidiabetes fraksi metanol dan fraksi kloroform daun Lavetar dengan metode aktivitas penghambatan enzim α-glukosidase serta menentukan kandungan senyawa aktif dengan menggunakan GCMS. Hasil skrining fitokimia menunjukkan bahwa senyawa aktif pada fraksi metanol adalah flavonoid dan tannin sedangkan fraksi kloroform mengandung senyawa flavonoid, tannin, dan saponin. Uji aktivitas penghambatan enzim α-glukosidase fraksi kloroform tergolong lemah sedangkan fraksi metanol tergolong sangat lemah dengan nilai nilai IC50 masing – masing sebesar 112,562 µg/mL dan 211,151 µg/mL. Hasil Interpretasi spektra FTIR dan skrining fitokimia menunjukkan bahwa gugus fungsi utama adalah flavanoid. Hasil analisis dengan GC-MS menunjukkan bahwa pada fraksi metanol terdapat 84 puncak senyawa dengan senyawa dominan yaitu 1-Heptatriacotanol (m/z = 190) dan fraksi kloroform terdapat 102 puncak senyawa dengan senyawa dominan yaitu cyclopropanebutanoic acid,2-[[2-[[2-[(2-pentylcyclopropyl)methyl]cyclopropyl]metyl]-,metyl ester (m/z = 270)

ISOLATION AND PRESENCE OF ANTIMALARIAL ACTIVITIES OF MARINE SPONGE <i>Xestospongia</i> sp.

Plasmodium falciparum, the agent of malignant malaria, is one of mankind's most severe scourges, mainly in the tropic world. Efforts to develop preventive vaccines or remedial drugs are handicapped by the parasite's rapid evolution of drug resistance. Here, we presented an advance work on examination of antimalarial component from marine life of Xestospongia sp., the study is based on hexane extraction method. The premier result, we obtained five fractions. Among these five fractions, the fourth has the most potent inhibitory against the growth of P. falciparum 3D7 with an IC50: 7.13 µg/mL. A compiled spectrum analysis, FTIR, 1H-NMR and GC-MS, revealed that the fourth fraction consisted abundantly of two secondary metabolites such as flavonoids and triterpenoids. Finally, our results suggest a plausible structure rooted to the base of ibuprofen

A Study on the Quality of Mako-mako River Water as Clean and Raw Water Source in Yembekiri Village

This study aims to determine the water quality of the Mako-mako river based on physical, chemical and microorganism parameters as well as the effect of metal and microorganism levels on the color of the water and sediment of the Mako-mako river. The method of sampling water, sediment and plankton by purposive sampling at three locations, namely the upstream, middle and downstream of the river. The concentrations of Fe and Mn in water and sediment were analyzed using AAS, while the identification of plankton using a binocular microscope. The results of the analysis of the water quality of the Mako-mako river show that the parameters of temperature, TDS, TSS and Mn are still below the water quality standard for class 1, except for the Fe and total coliform parameters whose concentrations have exceeded the water quality standard. The metal content of Fe in sediment is high and affects the color of the Mako-mako river sediment which is reddish brown to dark brown (deep). The presence of plankton with a low level of abundance and diversity index did not affect the color of the river water or the sediment of the Mako-mako riverSo that to use the Mako-mako river water as a source of raw water, clean water needs to go through a processing process.

PENGOLAHAN SAGU BERBASIS ZERO WASTE DI KABUPATEN MANOKWARI

The Community Partnership Program aims to build partnerships with sago farmers in zero waste-based sago processing. The program implementation of the activity showed that the application implementation of zero waste technology in sago processing in Koyani village, Manokwari Regency, immensely helped partners improve their knowledge, skills, and environmental sanitation. Partners Mitra have been skillful in applying semi-mechanical sago starch processing technology using shredded sago rasping machines to increase the sago starch production in both quantity and quality. Of sago starch. Mitra Partners has also made some variations in processed cakes products made of sago starch (sago starch-based cakes). This is one of the efforts to increase the utilization use of sago both as a source of local food for Papua and to support national food security programs based on local potential. Sago waste produced can be used to create made into sago waste briquettes. There is a need for venture capital support assistance and ongoing approaches continuously assistance from local government relevant agencies to develop small-scale creative industries based on local natural resources. --- Program Kemitraan Masyaakat ini bertujuan untuk membangun kemitraan dengan petani sagu dalam pengolahan sagu berbasis zero waste. Hasil pelaksanaan kegiatan menunjukkan bahwa program penerapan teknologi zero waste pada pengolahan sagu di Kampung Koyani Manokwari sangat membantu Mitra dalam meningkatkan pengetahuan, keterampilan, dan sanitasi lingkungan. Mitra telah terampil dalam menerapkan teknologi pengolahan pati sagu secara semi mekanis menggunakan mesin parut sagu sehingga meningkatkan kuantitas dan kualitas pati sagu. Mitra juga telah mampu membuat variasi olahan kue berbasis tepung sagu. Hal ini merupakan salah satu upaya untuk meningkatkan pemanfaatan sagu sebagai sumber pangan local Papua dan mendukung program ketahanan pangan nasional berbasis potensi lokal. Limbah ampas sagu yang dihasilkan dapat dibuat menjadi briket ampas sagu. Perlu adanya bantuan modal usaha dan pendampingan berkelanjutan dari instansi terkait agar mampu menciptakan industri kreatif skala kecil berbasis sumber daya alam local

MODEL ISOTERM FREUNDLICH DAN LANGMUIR OLEH ADSORBEN ARANG AKTIF BAMBU ANDONG (G. verticillata (Wild) Munro) DAN BAMBU ATER (G. atter (Hassk) Kurz ex Munro)

Freundlich and Langmuir Isotherms Model by Active Chorcoal Adsorbent Bamboo Andong  (G. verticillata (Wild) Munro) and Bamboo Ater (G. atter (Hassk) Kurz ex Munro)          Diazinon insecticide adsorption by two types of adsorbent, namely activated charcoal bamboo andong (G. verticillata (Wild) Munro) and bamboo ater (G. atter (Hassk) Kurzex Munro) at optimum conditions determined the maximum adsorption capacity of both types of adsorbent. Data analysison the effect of concentration on the adsorption capacity was used Langmuir and Freundlich isotherms equation. It was obtained. That  the curve of adsorption isotherms of the Langmuir isotherm better modeled with linear regression coefficients were relatively more approach 1 is R2 = 0,996 for both types of adsorbents. Langmuir isotherm equation obtained from adsorpsi maximum capacity of activated charcoal bamboo andong (G. verticillata (Wild) Munro) of  4.630 mg/g (1,433.10-5 mol/g) with K = 0,332 (Kmol/L)-1 and Eads at -2,750 kJ/mol, while the activated charcoal bamboo ater (G. atter (Hassk) Kurzex Munro) produce the maximum adsorption capacity of 1,786 mg/g (5,868.10-6 mol/g) with K = 0,202 (Kmol/L)-1 and Eads = -3,898 kJ/mol, so the adsorption of both types of adsorbents indicated experiencing a physical adsorption (physisorption / fisisorpsi).Keyword: G. verticillata (Wild) Munro, G. atter (Hassk) Kurz ex Munro, Adsorption, Diazinon,  actived charcoal  ABSTRAK          Adsorpsi insektisida diazinon oleh dua jenis adsorben, yaitu arang aktif bambu andong (G. verticillata (Wild) Munro) dan bambu ater (G. atter (Hassk) Kurz ex Munro) pada kondisi optimum bertujuan untuk menentukan kapasitas adsorpsi maksimum dari kedua jenis adsorben. Analisis data pengaruh konsentrasi terhadap kapasitas adsorpsi digunakan persamaan isoterm Langmuir dan Freundlich. Berdasarkan data yang diperoleh, kurva isoterm adsorpsi lebih mengikuti model isoterm Langmuir dengan koefisien regresi linier yang relatif lebih mendekati 1 yaitu R2 = 0,996 untuk kedua jenis adsorben. Dari persamaan isoterm Langmuir diperoleh kapasitas adsorpsi maksimum arang aktif bambu andong (G. verticillata (Wild) Munro) sebesar 4,630 mg/g (1,433.10-5 mol/g) dengan K = 0,332 (Kmol/L)-1 dan Eads sebesar -2,750 kJ/mol, sedangkan arang aktif bambu ater (G. atter (Hassk) Kurz ex Munro) menghasilkan kapasitas adsorpsi maksimum sebesar 1,786 mg/g (5,868.10-6 mol/g) dengan K = 0,202 (Kmol/L)-1 dan Eads = -3,898 kJ/mol, sehingga adsorpsi kedua jenis adsorben diindikasikan mengalami adsorpsi secara fisik (physisorption/ fisisorpsi).Kata kunci : G. verticillata (Wild) Munro, G. atter (Hassk) Kurz ex Munro Adsorpsi, Diazinon, Arang akti

ISOLATION AND PRESENCE OF ANTIMALARIAL ACTIVITIES OF MARINE SPONGE <i>Xestospongia</i> sp.

Plasmodium falciparum, the agent of malignant malaria, is one of mankind's most severe scourges, mainly in the tropic world. Efforts to develop preventive vaccines or remedial drugs are handicapped by the parasite's rapid evolution of drug resistance. Here, we presented an advance work on examination of antimalarial component from marine life of Xestospongia sp., the study is based on hexane extraction method. The premier result, we obtained five fractions. Among these five fractions, the fourth has the most potent inhibitory against the growth of P. falciparum 3D7 with an IC50: 7.13 µg/mL. A compiled spectrum analysis, FTIR, 1H-NMR and GC-MS, revealed that the fourth fraction consisted abundantly of two secondary metabolites such as flavonoids and triterpenoids. Finally, our results suggest a plausible structure rooted to the base of ibuprofen