Efficiencies of Quantum Optical Detectors

We propose a definition for the efficiency that can be universally applied to all classes of quantum optical detectors. This definition is based on the maximum amount of optical loss that a physically plausible device can experience while still replicating the properties of a given detector. We prove that detector efficiency cannot be increased using linear optical processing. That is, given a set of detectors, as well as arbitrary linear optical elements and ancillary light sources, it is impossible to construct detection devices that would exhibit higher efficiencies than the initial set.Comment: 5 pages, 3 figure

Towards Economic Models for MOOC Pricing Strategy Design

MOOCs have brought unprecedented opportunities of making high-quality courses accessible to everybody. However, from the business point of view, MOOCs are often challenged for lacking of sustainable business models, and academic research for marketing strategies of MOOCs is also a blind spot currently. In this work, we try to formulate the business models and pricing strategies in a structured and scientific way. Based on both theoretical research and real marketing data analysis from a MOOC platform, we present the insights of the pricing strategies for existing MOOC markets. We focus on the pricing strategies for verified certificates in the B2C markets, and also give ideas of modeling the course sub-licensing services in B2B markets

Bridging the empathy gap: Effects of brief mindfulness training on helping outgroup members in need

Witnessing others in need can be felt similarly to experiencing it oneself (empathy) and motivates assistance of those in need (prosocial action). It is well-documented that empathy can occur automatically, but when those in need are not members of a social ingroup, empathy and prosocial action are undermined. One major ingroup—outgroup division in American and in other countries is based on race. Although most condemn racial discrimination, empathy and prosocial action are often lower, however unintentionally, in interracial contexts. In light of this empathy gap, it is important to identify psychological factors that could bolster empathy and prosocial action toward racial outgroup members in need. This dissertation asked whether mindfulness training – cultivating present-centered, receptive attention to one’s ongoing experiences –increases social sensitivity toward racial outgroup members, and is based on pilot research indicating that a brief mindfulness induction increased empathy and prosocial action in such contexts. Healthy, self-identifying White women were randomized to either a brief (4-day) mindfulness training or a structurally-equivalent sham mindfulness training. Pre-post electroencephalographic measures of empathy toward video stimuli of outgroup members expressing sadness was assessed via prefrontal alpha frequency oscillations (i.e., frontal alpha asymmetry). Pre-post scenario-based spontaneous prosocial action toward Black individuals in need, and pre-post 14-day ecological momentary assessment (EMA) of empathy and prosocial action toward Black individuals (and other races) were conducted. Mindfulness training was expected to increase EEG- and EMA-based empathy toward Black individuals in need, as well as increase prosocial action toward such individuals in scenario and daily life (EMA) contexts. Opposite of what was hypothesized, MT reduced post-intervention empathic simulation, relative to ST, as measured by frontal alpha asymmetry. Consistent with hypotheses, however, MT increased empathic concern for outgroup members expressing sadness during video stimuli observation, and increased post-intervention scenario-based prosocial action. However, the hypothesis that MT would predict increases in pre- to post-intervention daily EMA-based prosocial action was not supported. Providing somewhat convergent evidence, trait mindfulness predicted more frequent pre-intervention scenario-based and daily prosocial action toward outgroup members; trait mindfulness was not related to pre-intervention video-based EEG and self-reported empathy outcomes. Together these results suggest that mindfulness can enhance some indicators or empathy and prosocial behavior in interracial contexts. Mechanisms and implications of the findings are discussed

Manipulating Paradigm and Attention via a Mindfulness Meditation Training Program Improves P300-Based BCI.

To date, only one study has situationally bolstered attentional resources in an effort to improve P300-BCI performance. The current study implements a 4-week Mindfulness Meditation Training Program (MMTP) as a nonmedicinal means to increase concentrative attention and to reduce lapses of attention; MMTP is expected to improve P300-BCI performance by enhancing attentional resources and reducing distractibility. A second aim is to test the efficacy of the checkerboard paradigm (CBP) against the standard row-column paradigm (RCP). Online results show that MMTP had greater accuracies than CTRL and that CBP outperformed the RCP. MMTP participants provided greater amplitude positive target responses, but these differences were not statistically significant. CBP had greater positive amplitude peaks and negative peaks than RCP. The discussion focuses on potential benefits of MMTP for P300-based BCIs, provides further support for the construct validity of mindfulness, and addresses future directions of the translational applicability of MMTP to in-home settings

An Investigation of Tax Assessors’ Perception of the Relationship Between Proactive Career Management Behaviors (PCMBs) and Career Success: Determining the most Valuable Career Management Behaviors

The purpose of this study was to investigate government and private-sector tax assessors’ perceptions of the relationship between proactive career management behaviors (PCMBs) and career success. The findings of the study established a foundation to assist government and private-sector tax assessor organizations with developing the human capital within and the careers of their employees. The study’s findings revealed that all four of the PCMBs (career planning, career self-exploration, environmental career exploration, and voluntary human capital development) had significant relationships to career success when tested with a multiple regression model. The study’s findings also revealed that there was no significant difference between government and private-sector tax assessors concerning the PCMB/career success relationship. The PCMBs and career success were also investigated by tax assessors’ gender, age, and education level differences. The study was grounded in aspects of career literature including expectancy theory, career management theory, career development theory, social cognitive career theory, the model of proactive behaviors, and boundaryless and protean career theory. There were also no significant differences in perception of career success for employment, gender, age groups, and educational level. The theoretical framework for this study supported previous findings from the literature

An Investigation of Tax Assessors’ Perception of the Relationship Between Proactive Career Management Behaviors (PCMBs) and Career Success: Determining the most Valuable Career Management Behaviors

The purpose of this study was to investigate government and private-sector tax assessors’ perceptions of the relationship between proactive career management behaviors (PCMBs) and career success. The findings of the study established a foundation to assist government and private-sector tax assessor organizations with developing the human capital within and the careers of their employees. The study’s findings revealed that all four of the PCMBs (career planning, career self-exploration, environmental career exploration, and voluntary human capital development) had significant relationships to career success when tested with a multiple regression model. The study’s findings also revealed that there was no significant difference between government and private-sector tax assessors concerning the PCMB/career success relationship. The PCMBs and career success were also investigated by tax assessors’ gender, age, and education level differences. The study was grounded in aspects of career literature including expectancy theory, career management theory, career development theory, social cognitive career theory, the model of proactive behaviors, and boundaryless and protean career theory. There were also no significant differences in perception of career success for employment, gender, age groups, and educational level. The theoretical framework for this study supported previous findings from the literature

Magnetic resonance imaging of myocardial strain after acute ST-segment-elevation myocardial infarction: a systematic review

The purpose of this systematic review is to provide a clinically relevant, disease-based perspective on myocardial strain imaging in patients with acute myocardial infarction or stable ischemic heart disease. Cardiac magnetic resonance imaging uniquely integrates myocardial function with pathology. Therefore, this review focuses on strain imaging with cardiac magnetic resonance. We have specifically considered the relationships between left ventricular (LV) strain, infarct pathologies, and their associations with prognosis. A comprehensive literature review was conducted in accordance with the PRISMA guidelines. Publications were identified that (1) described the relationship between strain and infarct pathologies, (2) assessed the relationship between strain and subsequent LV outcomes, and (3) assessed the relationship between strain and health outcomes. In patients with acute myocardial infarction, circumferential strain predicts the recovery of LV systolic function in the longer term. The prognostic value of longitudinal strain is less certain. Strain differentiates between infarcted versus noninfarcted myocardium, even in patients with stable ischemic heart disease with preserved LV ejection fraction. Strain recovery is impaired in infarcted segments with intramyocardial hemorrhage or microvascular obstruction. There are practical limitations to measuring strain with cardiac magnetic resonance in the acute setting, and knowledge gaps, including the lack of data showing incremental value in clinical practice. Critically, studies of cardiac magnetic resonance strain imaging in patients with ischemic heart disease have been limited by sample size and design. Strain imaging has potential as a tool to assess for early or subclinical changes in LV function, and strain is now being included as a surrogate measure of outcome in therapeutic trials

The REVERE project:Experiments with the application of probabilistic NLP to systems engineering

Despite natural language’s well-documented shortcomings as a medium for precise technical description, its use in software-intensive systems engineering remains inescapable. This poses many problems for engineers who must derive problem understanding and synthesise precise solution descriptions from free text. This is true both for the largely unstructured textual descriptions from which system requirements are derived, and for more formal documents, such as standards, which impose requirements on system development processes. This paper describes experiments that we have carried out in the REVERE1 project to investigate the use of probabilistic natural language processing techniques to provide systems engineering support

Genome-wide association study for calving performance using high-density genotypes in dairy and beef cattle

peer-reviewedBackground Calving difficulty and perinatal mortality are prevalent in modern-day cattle production systems. It is well-established that there is a genetic component to both traits, yet little is known about their underlying genomic architecture, particularly in beef breeds. Therefore, we performed a genome-wide association study using high-density genotypes to elucidate the genomic architecture of these traits and to identify regions of the bovine genome associated with them. Results Genomic regions associated with calving difficulty (direct and maternal) and perinatal mortality were detected using two statistical approaches: (1) single-SNP (single nucleotide polymorphism) regression and (2) a Bayesian approach. Data included high-density genotypes on 770 Holstein-Friesian, 927 Charolais and 963 Limousin bulls. Several novel or previously identified genomic regions were detected but associations differed by breed. For example, two genomic associations, one each on chromosomes 18 and 2 explained 2.49 % and 3.13 % of the genetic variance in direct calving difficulty in the Holstein-Friesian and Charolais populations, respectively. Imputed Holstein-Friesian sequence data was used to refine the genomic regions responsible for significant associations. Several candidate genes on chromosome 18 were identified and four highly significant missense variants were detected within three of these genes (SIGLEC12, CTU1, and ZNF615). Nevertheless, only CTU1 contained a missense variant with a putative impact on direct calving difficulty based on SIFT (0.06) and Polyphen (0.95) scores. Using imputed sequence data, we refined a genomic region on chromosome 4 associated with maternal calving difficulty in the Holstein-Friesian population and found the strongest association with an intronic variant in the PCLO gene. A meta-analysis was performed across the three breeds for each calving performance trait to identify common variants associated with these traits in the three breeds. Our results suggest that a portion of the genetic variation in calving performance is common to all three breeds. Conclusion The genomic architecture of calving performance is complex and mainly influenced by many polymorphisms of small effect. We identified several associations of moderate effect size but the majority were breed-specific, indicating that breed-specific alleles exist for calving performance or that the linkage phase between genotyped allele and causal mutation varies between breeds