Effect of retwisting parameters of splicing on the retained splice strength

Effect of three crucial parameters of splicing, exclusivelyrelated to retwisting operation of splicing, namely air pressure,retwisting time and overlapping length on retained splicestrength (RSS) has been studied. During this study, theparameters related to untwisting are kept constant based on thevisual untwisting performance. Three-factor three-level Box-Behnken design is employed on three different cotton yarncounts (20s Ne, 40s Ne and 60s Ne), produced by ring spinning.Interactive effects of parameters have also been analyzedthrough contour plots and optimization conditions are achievedusing the statistical software called Minitab. The optimizationconditions can be used as a guide to set the splicer parameters. Itis observed that average retained splice strength of the yarnincreases with the increase in yarn count. Higher RSS can beobtained with the combination of lower compressed air pressurewith relatively higher retwisting time

How to make Dupire's local volatility work with jumps

There are several (mathematical) reasons why Dupire's formula fails in the non-diffusion setting. And yet, in practice, ad-hoc preconditioning of the option data works reasonably well. In this note we attempt to explain why. In particular, we propose a regularization procedure of the option data so that Dupire's local vol diffusion process recreates the correct option prices, even in manifest presence of jumps

Reluctance of general practice staff to register patients without documentation: a qualitative study in North East London.

BACKGROUND: Lack of access to documentation is a key barrier to GP registration, despite NHS England guidance stating that documents are not required. Staff attitudes and practice regarding registration of those without documentation are under- researched. AIM: To understand the processes through which registration might be refused for those without documents, and the factors operating to influence this. DESIGN AND SETTING: Qualitative study conducted in general practice across three clinical commissioning groups in North East London. METHOD: In total, 33 participants (GP staff involved in registering new patients) were recruited through email invitation. Semi-structured interviews and focus groups were conducted. Data were analysed using Braun and Clarke's reflexive thematic analysis. Two social theories informed this analysis: Lipsky's street-level bureaucracy and Bourdieu's theory of practice. RESULTS: Despite good knowledge of guidance, most participants expressed reluctance to register those without documentation, often introducing additional hurdles or requirements in their everyday practice. Two explanatory themes were generated: that those without documents were perceived as burdensome, and/or that moral judgements were made about their deservedness to finite resources. Participants described a context of high workload and insufficient funding. Some felt that GP services should be restricted by immigration status, as is widespread in secondary care. CONCLUSION: Improving inclusive registration practice requires addressing staff concerns, supporting navigation of high workloads, tackling financial disincentives to registering transient groups, and challenging narratives that undocumented migrants represent a 'threat' to NHS resources. Furthermore, it is imperative to acknowledge and address upstream drivers, in this instance the Hostile Environment

Model Pembelajaran Kooperatif Tipe Stad (Student Teams Achievement Division) Dikombinasikan dengan Media Animasi pada Materi Laju Reaksi Kelas XI SMA Negeri 1 Palu

Students have difficulties in understanding chemistry subject contained mathematical calculation like on reaction rate topic. Cooperative learning model STAD type can be an alternative for the material contained calculation whereas animation media is for conceptual understanding. The objective of the research was to determine the influence of cooperative learning model STAD type combined with animation media for the eleventh grade students of SMA Negeri 1 Palu in academic year 2012/2013 toward the students' learning outcome on reaction rate material. This research was quasy experimental using posttest-only control group design. The population was the whole eleventh grade students of science program with the sample determination using purposive sampling method. The sample were class of science program 2 as the experimental class which using cooperative learning model STAD type with animation media whereas class of science program 4 as the control one which using convensional learning method. The research results showed that cooperative learning model STAD type combined with animation media at reaction rate material gave students' learning outcome higher than convensional method

N-dimensional electron in a spherical potential: the large-N limit

We show that the energy levels predicted by a 1/N-expansion method for an N-dimensional Hydrogen atom in a spherical potential are always lower than the exact energy levels but monotonically converge towards their exact eigenstates for higher ordered corrections. The technique allows a systematic approach for quantum many body problems in a confined potential and explains the remarkable agreement of such approximate theories when compared to the exact numerical spectrum.Comment: 8 pages, 1 figur

DNA methylation profiling of the human major histocompatibility complex: A pilot study for the Human Epigenome Project

The Human Epigenome Project aims to identify, catalogue, and interpret genome-wide DNA methylation phenomena. Occurring naturally on cytosine bases at cytosine-guanine dinucleotides, DNA methylation is intimately involved in diverse biological processes and the aetiology of many diseases. Differentially methylated cytosines give rise to distinct profiles, thought to be specific for gene activity, tissue type, and disease state. The identification of such methylation variable positions will significantly improve our understanding of genome biology and our ability to diagnose disease. Here, we report the results of the pilot study for the Human Epigenome Project entailing the methylation analysis of the human major histocompatibility complex. This study involved the development of an integrated pipeline for high-throughput methylation analysis using bisulphite DNA sequencing, discovery of methylation variable positions, epigenotyping by matrix-assisted laser desorption/ionisation mass spectrometry, and development of an integrated public database available at http://www.epigenome.org. Our analysis of DNA methylation levels within the major histocompatibility complex, including regulatory exonic and intronic regions associated with 90 genes in multiple tissues and individuals, reveals a bimodal distribution of methylation profiles (i.e., the vast majority of the analysed regions were either hypo- or hypermethylated), tissue specificity, inter-individual variation, and correlation with independent gene expression data

Baseline characteristics and treatment-emergent risk factors associated with cerebrovascular event and death with risperidone in dementia patients

BACKGROUND: Use of antipsychotics to treat behavioural symptoms of dementia has been associated with increased risks of mortality and stroke. Little is known about individual patient characteristics that might be associated with bad or good outcomes. AIMS: We examined the risperidone clinical trial data to look for individual patient characteristics associated with these adverse outcomes. METHOD: Data from all double-blind randomised controlled trials of risperidone in dementia patients (risperidone n = 1009, placebo n = 712) were included. Associations between characteristics and outcome were analysed based on crude incidences and exposure-adjusted incidence rates, and by time-to-event analyses using Cox proportional hazards regression. Interactions between treatment (risperidone or placebo) and characteristic were analysed with a Cox proportional hazards regression model with main effects for treatment and characteristic in addition to the interaction term. RESULTS: Baseline complications of depression (treatment by risk factor interaction on cerebrovascular adverse event (CVAE) hazard ratio (HR): P = 0.025) and delusions (P = 0.043) were associated with a lower relative risk of CVAE in risperidone-treated patients (HR = 1.47 and 0.54, respectively) compared to not having the complication (HR = 5.88 and 4.16). For mortality, the only significant baseline predictor in patients treated with risperidone was depression, which was associated with a lower relative risk (P<0.001). The relative risk of mortality was increased in risperidone patients treated with anti-inflammatory medications (P = 0.021). CONCLUSIONS: Only anti-inflammatory medications increased mortality risk with risperidone. The reduced risks of CVAE in patients with comorbid depression and delusions, and of mortality with depression, may have clinical implications when weighing the benefits and risks of treatment with risperidone in patients with dementia

Flexural Cracks in Fiber-Reinforced Concrete Beams with Fiber-Reinforced Polymer Reinforcing Bars

Fiber-reinforced polymer (FRP) reinforcing bars have attracted considerable attention for applications where corrosion of steel reinforcement is problematic. Due to the generally low elastic modulus and poor bond characteristics of FRP as compared to steel reinforcing bars, the use of FRP results in larger crack widths under service loads. Fiber-reinforced concrete (FRC) is proposed for use with FRP to reduce crack widths. The work presented herein includes the results from 16 beams tested under four-point bending with either Grade 420 (Grade 60) steel or FRP reinforcing bars, and either plain concrete or FRC. A modified Gergely-Lutz model was applied to the measured crack widths to calculate bond coefficients that were used to quantify the effectiveness of FRC in reducing crack widths. In the beams with steel reinforcing bars, the FRC was found to have little influence on crack widths. In the beams with FRP reinforcing bars, the FRC was found to significantly reduce maximum crack widths