5,024 research outputs found

    An environmental assessment of the summer plankton in the vicinity of the C.P. Crane generating station

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    A preliminary survey of summer plankton in ·waters surrounding the C. P. Crane generating station in Bengies, Maryland, revealed several possible effects of plant operation. These perturbations were separated into apparent small-scale and large-scale effects: Small-scale effects were limited to the immediate discharge region of Saltpeter Creek and included (1) occasional elevation of temperatures at the surface (in August) to above the lethal limit for most zooplankton and sufficiently high to inhibit photosynthesis, (2) a decrease in chlorophyll-a, seen in July and August, (3) a sharp decrease in productivity, also in July and August, and (4) absence of a common cladoceran in July. Possible large-scale effects covered most of the sampled area and included (1) a reduction in diversity due to displacement of a natural freshwater community with an oligohaline one that has been altered somewhat by the addition of heat, (2) increased temperature and productivity throughout Saltpeter Creek and the lower Gunpowder River when higher ambient temperatures coincide with peak demand for electric power and (3) an increase in the barnacle population by the provision of submerged power plant structures for settlement of larvae and the distribution of larvae throughout the system via cooling water discharged into Saltpeter Creek

    An analysis of phytoplankton, microzooplankton and mesozooplankton populations in the vicinity of the C. P. Crane generating station during the spring months of 1979

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    Sampling of spring 1979 plankton populations at the C.P. Crane site was conducted at 15 stations during six sampling periods for phytoplankton, at 5 stations monthly from March to June for microzooplankton and monthly at 14 stations for mesozooplankton. Ancillary physical data were collected at all the above stations, while nutrients were measured twice in April

    Current Chemotherapeutic Management of Patients with Gestational Trophoblastic Neoplasia

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    Gestational trophoblastic neoplasia (GTN) describes a heterogeneous group of interrelated lesions that arise from abnormal proliferation of placental trophoblasts. GTN lesions are histologically distinct, malignant lesions that include invasive hydatidiform mole, choriocarcinoma, placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT). GTN tumors are generally highly responsive to chemotherapy. Early stage GTN disease is often cured with single-agent chemotherapy. In contrast, advanced stage disease requires multiagent combination chemotherapeutic regimens to achieve a cure. Various adjuvant surgical procedures can be helpful to treat women with GTN. Patients require careful followup after completing treatment and recurrent disease should be aggressively managed. Women with a history of GTN are at increased risk of subsequent GTN, hence future pregnancies require careful monitoring to ensure normal gestational development. This article will review the workup, management and followup of women with all stages of GTN as well as with recurrent disease

    A metal ion-binding site in the kringle region of bovine prothrombin fragment 1.

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    45Ca(II) binding studies (equilibrium dialysis) on the kringle domain of bovine prothrombin fragment 1 were conducted using a mixture of peptides (residues 43-156 and 46-156) resulting from limited alpha-chymotryptic hydrolysis of fragment 1. Analysis of the Scatchard plot of these data indicates a single, low affinity Ca(II)-binding site to be present. Similar results were obtained from studies on the decarboxylated fragment 1 derivative, 10-gamma-MGlu-fragment 1. Acetylation of bovine fragment 1 in the absence of Ca(II) or Mg(II) ions results in the loss of the metal ion-promoted quenching of the intrinsic Trp fluorescence of the protein and the Ca(II)-mediated binding to phosphatidylserine/phosphatidylcholine (PS/PC) vesicles. The acetylation of the NH2 alpha-group of Ala-1 has been shown (Welsch, D. J., and Nelsestuen, G. L. (1988) Biochemistry 27, 4946-4952) to abolish the PS/PC binding property of fragment 1. The present study demonstrates that acetylation of a second site possibly Ser-79 or Thr-81 using the conditions described in the preceding paper results in loss of both the fluorescence transition and the Ca(II)-mediated PS/PC binding of the resulting protein derivative. Removal of the O-acetyl group at the Ser-79/Thr-81 site is accomplished by aminolysis with 0.2 M hydroxylamine, pH 10, 50 degrees C; the fluorescence transition is partially restored. PS/PC binding is partially restored if the NH2 alpha-group of Ala-1 is trinitrophenylated but is not restored if the NH2 alpha-group of Ala-1 is acetylated. We conclude that the Ser-79/Thr-81 site may represent a portion of the metal ion-binding site within the kringle domain of fragment 1. Occupancy of this site by a Ca(II) ion appears to be important in the binding of the protein to PS/PC vesicles

    Monte Carlo simulations of ordering in ferromagnetic-antiferromagnetic bilayers

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    Monte Carlo simulations have been used to study phase transitions on coupled anisotropic ferro/antiferromagnetic (FM/AFM) films of classical Heisenberg spins. We consider films of different thicknesses, with fully compensated exchange across the FM/AFM interface. We find indications of a phase transition on each film, occuring at different temperatures. It appears that both transition temperatures depend on the film thickness.Comment: Revtex, 4 pages, 4 figure

    Pylons ablaze: Examining the role of 5G COVID-19 conspiracy beliefs and support for violence

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    Amid increased acts of violence against telecommunication engineers and property, this pre‐registered study (N = 601 Britons) investigated the association between beliefs in 5G COVID‐19 conspiracy theories and the justification and willingness to use violence. Findings revealed that belief in 5G COVID‐19 conspiracy theories was positively correlated with state anger, which in turn, was associated with a greater justification of real‐life and hypothetical violence in response to an alleged link between 5G mobile technology and COVID‐19, alongside a greater intent to engage in similar behaviours in the future. Moreover, these associations were strongest for those highest in paranoia. Furthermore, we show that these patterns are not specific to 5G conspiratorial beliefs: General conspiracy mentality was positively associated with justification and willingness for general violence, an effect mediated by heightened state anger, especially for those most paranoid in the case of justification of violence. Such research provides novel evidence on why and when conspiracy beliefs may justify the use of violence

    Disability, Work and Cash Benefits

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    This book examines the economic consequences of work disabilities, and public and private interventions that might enable disabled individuals to enter the work force for the first time, remain at work, or return to work. Three groups of papers are presented. The first group examines ways that labor market changes, policy interventions and individual choices shape the work force. The next analyzes both public and private return to work policies for the work disabled and for those with a severely disabling condition. The final group focuses on the specific needs of the disabled that affect their work force participation, including access to health care, personal assistance and assistive technologies.https://research.upjohn.org/up_press/1195/thumbnail.jp
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