55 research outputs found

    Bumble bee parasite strains vary in resistance to phytochemicals

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    Nectar and pollen contain diverse phytochemicals that can reduce disease in pollinators. However, prior studies showed variable effects of nectar chemicals on infection, which could reflect variable phytochemical resistance among parasite strains. Inter-strain variation in resistance could influence evolutionary interactions between plants, pollinators, and pollinator disease, but testing direct effects of phytochemicals on parasites requires elimination of variation between bees. Using cell cultures of the bumble bee parasite Crithidia bombi, we determined (1) growth-inhibiting effects of nine floral phytochemicals and (2) variation in phytochemical resistance among four parasite strains. C. bombi growth was unaffected by naturally occurring concentrations of the known antitrypanosomal phenolics gallic acid, caffeic acid, and chlorogenic acid. However, C. bombi growth was inhibited by anabasine, eugenol, and thymol. Strains varied >3-fold in phytochemical resistance, suggesting that selection for phytochemical resistance could drive parasite evolution. Inhibitory concentrations of thymol (4.53-22.2 ppm) were similar to concentrations in Thymus vulgaris nectar (mean 5.2 ppm). Exposure of C. bombi to naturally occurring levels of phytochemicals—either within bees or during parasite transmission via flowers—could influence infection in nature. Flowers that produce antiparasitic phytochemical, including thymol, could potentially reduce infection in Bombus populations, thereby counteracting a possible contributor to pollinator decline

    Influence of small inertia on Jeffery orbits

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    We experimentally investigate the rotational dynamics of neutrally buoyant axisymmetric particles in a simple shear flow. A custom-built shearing cell and a multi-view shape-reconstruction method are used to obtain direct measurements of the orientation and period of rotation of particles having oblate and prolate shapes (such as spheroids and cylinders) of varying aspect ratios. By systematically changing the viscosity of the fluid, we examine the effect of inertia (which may be originated from either phase) on the dynamical behaviour of these suspended particles up to a particle Reynolds number of approximately one. While no significant effect on the period of rotation is found in this small-inertia regime, a systematic drift among several rotations toward limiting stable orbits is observed. Prolate particles are seen to drift towards the tumbling orbit in the plane of shear, whereas oblate particles are driven either to the tumbling or to the vorticity-aligned spinning orbits, depending on their initial orientation. These results are compared with recent small-inertia asymptotic theories, assessing their range of validity, as well as to numerical simulations in the small-inertia regime for both prolate and oblate particles

    Particle size effects on an optical fiber sensor response

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    Mesures in situ de la concentration des matiĂšres en suspension : mise au point d'une sonde optique

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    Extrait de documentTheoterical and experimental studies performed by the " Groupe d'Instrumentation des Procédés et SystÚmes en Ecoulement (GIPSE) " led to the design of an optical fibre turbidimeter using mechanisms of retrodiffusion and attenuation of light by particles in suspension in water.Les études théoriques et expérimentales menées au sein du Groupe d'Instrumentation des Procédés et SystÚmes en Ecoulement (GIPSE) ont abouti à la mise au point d'un turbidimÚtre à fibres optiques utilisant les mécanismes de rétrodiffusion et d'atténuation de la lumiÚre par des particules en suspension dans l'eau

    Information needs on nutrition in link to cancer prevention among cancer patients, high-risk individuals and general population – A national cross-sectional study

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    International audienceBackground & aims:Nutrition is one of the fundamentals of cancer prevention. Knowing what are the patients’ needs and beliefs in terms of “nutrition and cancer” information helps tailor future nutritional interventions. The aim of this study was to evaluate specific information needs about “nutrition in relation to cancer prevention”, including primary and tertiary prevention, among cancer patients, cancer free individuals, and genetic high cancer risk individuals.Methods:This online survey was shared within two large National cancer social networks and proposed to all attendees and carers of a comprehensive cancer center.Results:2887 individuals answered the survey (of whom 33% were cancer patients, 13% high-risk individuals and 55% participants of the general population). More than 80% of participants were women, had at least a high school degree. Median body mass index was 23.2 kg/m2. Eleven percent (n =321) were following a diet, mostly low carbohydrate and weight-loss diets. Around 70% of all categories felt they lacked information on nutrition and cancer interplays. Only 12% of cancer patients (n ÂŒ 108) considered they had received enough information on nutrition during their care pathway. A majority of participants agreed that food can modify cancer risk (93%, n =2526) and 66% (n ÂŒ 1781) considered that nutrition should be personalized according to the risk of cancer. Only twenty-nine percent (n = 792) believed that eating 5 fruits and vegetables a day was enough to avoid cancer, but 64% (n = 1720) thought that dietary supplements could help obtain a better health. All proposed nutrition topics were considered important by the participants.Conclusions:Although cancer patients and cancer-free respondents, whether at high risk of cancer or not, share a common broad interest on the interplay between nutrition and cancer and seek after more information on this topic, some false beliefs are observed. Healthcare providers could successfully propose more evidence-based information to these populations
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