Disk-Like Structure in the Semi-Regular Pulsating Star, X Her

The author reports a result of an interferometric observation of the semiragular pulsating star with an unusual narrow molecular line profile, X Her, in the CO J=1-0 line with the Berkeley-Illinois-Maryland array. In the CO spectrum, a double-component profile (including narrow and broad components) is seen as reported by previous observations. The narrow component consists of two spiky peaks. The spatial structure of the board component shows bipolar shape, and that of the narrow component shows an elliptical/spherical shape. The two peaks in the narrow component show a systematic difference in the integrated intensity map. The kinematical and geometrical properties of the narrow component are reminiscent of a Keplerian rotating disk with the central mass of 0.9 M_sun, though an interpretation by an expansion disk seems to be more natural. A secondary bipolar flow instead of the disk cannot be fully excluded as an interpretation of the narrow line.Comment: 12 pages, 4 figues, accepted for publication in Ap

Role of the unique N-terminal domain of CtBP2 in determining the subcellular localisation of CtBP family proteins

BACKGROUND: CtBP1 and CtBP2 are transcriptional co-repressors that modulate the activity of a large number of transcriptional repressors via the recruitment of chromatin modifiers. Many CtBP-regulated proteins are involved in pathways associated with tumorigenesis, including TGF-beta and Wnt signalling pathways and cell cycle regulators such as RB/p130 and HDM2, as well as adenovirus E1A. CtBP1 and CtBP2 are highly similar proteins, although evidence is emerging that their activity can be differentially regulated, particularly through the control of their subcellular localisation. CtBP2s from diverse species contain a unique N-terminus, absent in CtBP1 that plays a key role in controlling the nuclear-cytoplasmic distribution of the protein.RESULTS: Here we show that amino acids (a.a.) 4-14 of CtBP2 direct CtBP2 into an almost exclusively nuclear distribution in cell lines of diverse origins. Whilst this sequence contains similarity to known nuclear localisation motifs, it cannot drive nuclear localisation of a heterologous protein, but rather has been shown to function as a p300 acetyltransferase-dependent nuclear retention sequence. Here we define the region of CtBP2 required to co-operate with a.a. 4-14 to promote CtBP2 nuclear accumulation as being within a.a. 1-119. In addition, we show that a.a. 120-445 of CtBP2 can also promote CtBP2 nuclear accumulation, independently of a.a. 4-14. Finally, CtBP1 and CtBP2 can form heterodimers, and we show that the interaction with CtBP2 is one mechanism whereby CtBP1 can be recruited to the nucleus.CONCLUSION: Together, these findings represent key distinctions in the regulation of the functions of CtBP family members that may have important implications as to their roles in development, and cell differentiation and survival.<br/

Instanton operators in five-dimensional gauge theories

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are creditedN.L. is supported in part by STFC grant ST/J002798/1. C.P. is a Royal Society Research Fellow.N.L. is supported in part by STFC grant ST/J002798/1. C.P. is a Royal Society Research Fellow.N.L. is supported in part by STFC grant ST/J002798/1. OPen Aceess funded by SCOAP

Scalable Parallel Numerical Constraint Solver Using Global Load Balancing

We present a scalable parallel solver for numerical constraint satisfaction problems (NCSPs). Our parallelization scheme consists of homogeneous worker solvers, each of which runs on an available core and communicates with others via the global load balancing (GLB) method. The parallel solver is implemented with X10 that provides an implementation of GLB as a library. In experiments, several NCSPs from the literature were solved and attained up to 516-fold speedup using 600 cores of the TSUBAME2.5 supercomputer.Comment: To be presented at X10'15 Worksho

All-fibre source of amplitude-squeezed light pulses

An all-fibre source of amplitude squeezed solitons utilizing the self-phase modulation in an asymmetric Sagnac interferometer is experimentally demonstrated. The asymmetry of the interferometer is passively controlled by an integrated fibre coupler, allowing for the optimisation of the noise reduction. We have carefully studied the dependence of the amplitude noise on the asymmetry and the power launched into the Sagnac interferometer. Qualitatively, we find good agreement between the experimental results, a semi-classical theory and earlier numerical calculations [Schmitt etl.al., PRL Vol. 81, p.2446, (1998)]. The stability and flexibility of this all-fibre source makes it particularly well suited to applications in quantum information science

Molecular Lines in Bok Globules and Around Herbig Ae/be Stars

This paper is intended as part of a more extensive molecular line survey in star forming regions along the evolutionary track of a collapsing cloud toward a young stellar object. We have studied a sample of seven small dark clouds (Bok globules) and eight Herbig Ae/Be stars in the J=1->0 transition of HCO$^{+}$, H$^{13}$CO$^{+}$, HCN and H$^{13}$CN. The choice of these molecules is determined by the simple chemistry and the predicted high abundance of the reactants leading to their formation. The isotopically substituted species (isotopomers), H$^{13}$CO$^{+}$ and H$^{13}$CN, were observed in order to determine, whenever possible, the optical thickness of the main species. The most abundant isotopomers were found in almost all the sources (detection rate 70-90\%). Those sources which exhibited the strongest signals were also searched for the $^{13}$C isotopomers. H$^{13}$CO$^{+}$ was found in one dark cloud and around three Herbig Ae/Be stars, while H$^{13}$CN around only one star. The column densities for each species and the physical conditions of the objects were derived whenever the observational data allowed it.Comment: 16 pages plus 6 figures available in hardcopy from [email protected] LaTEX ver. 2.09, BAP 11-1993-036-DD

Fiber Optic Tactical Local Network (FOTLAN)

A 100 Mbit/s FDDI (fiber distributed data interface) network interface unit is described that supports real-time data, voice and video. Its high-speed interrupt-driven hardware architecture efficiently manages stream and packet data transfer to the FDDI network. Other enhancements include modular single-mode laser-diode fiber optic links to maximize node spacing, optic bypass switches for increased fault tolerance, and a hardware performance monitor to gather real-time network diagnostics

Aspects of Type 0 String Theory

A construction of compact tachyon-free orientifolds of the non-supersymmetric Type 0B string theory is presented. Moreover, we study effective non-supersymmetric gauge theories arising on self-dual D3-branes in Type 0B orbifolds and orientifolds.Comment: 9 pages, LATEX; submitted to Proceedings of Strings '9

Ariel - Volume 1 Number 3

Copyright 1969 Arie