83 research outputs found
Onderzoek naar de verbetering van tongvangsten in de outrigvisserij
- Publication venue
- IMARES
- Publication date
- Field of study
De laatste jaren is de boomkorvisserij onder druk komen te staan vanwege de effecten van deze methode van vissen op het mariene ecosysteem. De recente stijging van gasolieprijzen en daarmee samenhangende brandstofkosten van rond de 0.20 âŹ/ltr tot ca. 0.70 âŹ/ltr brengen de rendabiliteit van deze visserijsector in gevaar. Er wordt dan ook betwijfelt of de huidige boomkorvisserij nog toekomst heeft . Om deze redenen zoeken vissers naar alternatieve vangstmethoden, zoals de âoutrigâ visserij. Deze methode, waarbij met een bordentrawl vanuit de gieken van een boomkorschip wordt gevist levert een aanzienlijke brandstofbesparing op, maar de vangst van tong is doorgaans minder door geringer bodemcontact
Praktijknetwerk Sumwing Zuid
- Publication venue
- 'Institute of Marine Engineering, Science and Technology (IMarEST)'
- Publication date
- Field of study
De SumWing is een recente aanpassing van het conventionele boomkortuig. Het vistuig heeft geen sloffen meer en wordt op de bodem gehouden door middel van een taster. Dit levert een brandstofbesparing op. Dit nieuwe tuig is aanvankelijk ontwikkeld voor de vlakke grond in de noordelijke Noordzee. In dit project is gekeken hoe dit vistuig geschikt kan worden gemaakt voor het vissen âin de puntenâ (d.w.z. ongelijke visgronden met zandribbels) in de zuidelijke Noordzee
Major liver resection results in early exacerbation of insulin resistance, and may be a risk factor of developing overt diabetes in the future
- Author
- A Thorell
- A Tokunaga
- Adam Durczynski
- AM Owyang
- Anna Borkowska
- C Weyer
- CH Chang
- Dariusz Szymanski
- F Tacke
- FG Fernandez
- G Berghe Van den
- G Berghe Van den
- G Berghe Van den
- H Maeda
- Janusz Strzelczyk
- Justyna Chalubinska
- Katarzyna Wojciechowska-Durczynska
- KG Alberti
- L Czupryniak
- Leszek Czupryniak
- M Sika
- MH Shanik
- N Wlazlo
- Piotr Hogendorf
- R Schindler
- RA DeFronzo
- RP Cornell
- S Virani
- SA Dello
- T Nishida
- T Okabayashi
- T Utsunomiya
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Thyroxine increases Serca2 and Ryr2 gene expression in heart failure rats with euthyroid sick syndrome
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
The impact of diabetes on the pathogenesis of sepsis
- Author
- A HernĂĄndez-Mijares
- A Khaira
- A Mallis
- A Morelli
- A Mowat
- A Tamer
- A Wykretowicz
- AC Cheng
- AC MacCuish
- AG Bertoni
- AJ Sbarra
- AK Daoud
- AK Rao
- AM Deakin
- AM Esper
- B Andersen
- B Zingarelli
- BB Graham
- BI Restrepo
- BR Shah
- C Douvin
- C FiçicioÄlu
- C Geisler
- CH Hennekens
- CH Mijovic
- CL Tsai
- CW Park
- D Balasoiu
- D Kiliç
- D Nandy
- D Tater
- D Vergani
- D Zozuliñska
- DEG Griesdale
- DJ Cook
- DP Speert
- DW Landry
- E Fitzgerald
- E Handmann
- E Karlsson
- EF Schisterman
- EJ Rayfield
- EP Joslin
- ER Hentzen
- F Jenhani
- F-C Tsai
- FA McAlister
- G Berghe van den
- G Berghe van den
- G Cooper
- G. C. K. W. Koh
- GC Jones
- GCKW Koh
- H Dziatkowiak
- H Ghanim
- H Taki
- HR Hill
- J Casey
- J Li
- J Michaeli
- J MyĆliwska
- J-L Vincent
- JA Carton
- JB Kornum
- JC Costa Da Jr
- JC Costa Da Jr
- JC Davin
- JC Pickup
- JD Bagdade
- JD Bagdade
- JD Bagdade
- JD Bybee
- JE Gregory
- JI Casey
- JK Moen
- JM Alexiewicz
- JP Leroux
- JR Chandler
- JS Tan
- JT King Jr
- KE Dooley
- KP Bouter
- KZ Vardakas
- LB Brydak
- LMAJ Muller
- M Delamaire
- M Kitahara
- M Lamkanfi
- M Libert
- M Michalia
- M Morigi
- M Moss
- M Muszkat
- M Spatz
- MC Foss-Freitas
- ME Falagas
- ME Stegenga
- ME Stegenga
- ME Stegenga
- ME Stegenga
- ME Stegenga
- MJ Carfrae
- MJ Fine
- MK Hostetter
- MN Gong
- N Eibl
- N Grinberg
- N Sato
- NA Maianski
- NB Standen
- NH Valerius
- NJ Davidson
- O Lassar
- P Dandona
- P Dandona
- P Mohanty
- P Pozzilli
- P Pozzilli
- P Schuetz
- R Richardson
- RD Nelson
- RDR Liberatore Jr
- RM Wilson
- RS Watson
- RW Thomsen
- RW Thomsen
- S Boyden
- S Finfer
- S Katz
- S Lee
- S Neelamegham
- S Takami
- S Warren
- S Warrillow
- S Yende
- S-M Alavian
- S. J. Peacock
- SE Geerlings
- SV Shah
- T Ali
- T. van der Poll
- TE Ahlering
- TK Hansen
- TME Davis
- TR Beam Jr
- TS Altannavch
- UK Prospective Diabetes Study (UKPDS) Group
- V Brinkmann
- V Esmann
- V Kaplan
- V Rattan
- W-T Wu
- W. J. Wiersinga
- WC Aird
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2011
- Field of study
Diabetes is associated with an increased susceptibility to infection and sepsis. Conflicting data exist on whether the mortality of patients with sepsis is influenced by the presence of diabetes, fuelling the ongoing debate on the benefit of tight glucose regulation in patients with sepsis. The main reason for which diabetes predisposes to infection appears to be abnormalities of the host response, particularly in neutrophil chemotaxis, adhesion and intracellular killing, defects that have been attributed to the effect of hyperglycaemia. There is also evidence for defects in humoral immunity, and this may play a larger role than previously recognised. We review the literature on the immune response in diabetes and its potential contribution to the pathogenesis of sepsis. In addition, the effect of diabetes treatment on the immune response is discussed, with specific reference to insulin, metformin, sulphonylureas and thiazolidinediones
An early history of T cell-mediated cytotoxicity.
- Author
- A Altman
- A Conzelmann
- A Govaerts
- A Kupfer
- A Rossin
- A Xin
- A Yamada
- AB Adams
- AE Stuart
- AH Sharpe
- AO Hueber
- AR Sanderson
- AR Sanderson
- B Bonavida
- B Geiger
- B Kindred
- B Lowin
- B Lowin
- BC Trauth
- BD Brondz
- BD Brondz
- BD Brondz
- BD Brondz
- C Blank
- CG Lobe
- CH June
- CJ Sanderson
- CJ Sanderson
- CL Ewen
- CM Henry
- CM Walsh
- CR Monks
- CS Henney
- D Balomenos
- D Chowdhury
- D KĂ€gi
- D KĂ€gi
- D Masson
- D Masson
- D Masson
- D Redelman
- D Schubert
- D Zagury
- DB Amos
- DB Wilson
- DH Katz
- DR Leach
- E Martz
- E Martz
- E Möller
- E Rouvier
- E Zuccato
- EA Tivol
- EJ Wherry
- ER Podack
- ER Podack
- F Albert
- F Dotiwala
- F Dotiwala
- F Rieux-Laucat
- F Stegelmann
- FS Hodi
- G Berke
- G Berke
- G Berke
- G Berke
- G Berke
- G Bossi
- G Dennert
- G Gross
- G Gross
- G Holm
- G Trenn
- GA Granger
- GA Granger
- Gillian M. Griffiths
- GM Shearer
- H Acha-Orbea
- H Blomgren
- H Cantor
- H Friedman
- H Kojima
- H Koprowski
- H Lin
- H Nishimura
- H Nishimura
- H Nishimura
- H Schmidt
- H Wagner
- H Wigzell
- H Wigzell
- H Wigzell
- HK Gershenfeld
- HL Ostergaard
- HS Koren
- HS Kuehn
- I Voskoboinik
- ICM MacLennan
- J Desbarats
- J Pachlopnik Schmid
- J Sprent
- J-C Cerottini
- J-C Cerottini
- J-F Brunet
- J-F Brunet
- J-F Brunet
- J-F Brunet
- JA Lopez
- JC Stinchcombe
- JC Stinchcombe
- JD-E Young
- JD-E Young
- JD-E Young
- JFR Kerr
- JH Russell
- JK Burkhardt
- JW Shiver
- K Man
- KT Brunner
- KT Brunner
- L Dyck
- L Shi
- L Shi
- LH Glimcher
- M Criado
- M Crone
- M Frick
- M Gallo Le
- M Huber
- M Muzio
- M Nabholz
- M Poenie
- M Tanaka
- MD Kramer
- ME Peter
- MF Broek Van den
- MJ Martinez-Lorenzo
- MJ Smyth
- MK Gately
- ML Lohmann-Matthes
- MM Simon
- MN Wykes
- MP Boldin
- MS Pasternack
- MS Pasternack
- MT Ochoa
- NH Ruddle
- O Berg
- O Hamid
- P Golstein
- P Golstein
- P Golstein
- P Golstein
- P Golstein
- P Golstein
- P Golstein
- P Lonai
- P Perlmann
- P Perlmann
- P Schneider
- P Waterhouse
- PA Henkart
- PA Henkart
- PE Baker
- PH Krammer
- Pierre Golstein
- PJ Peters
- PS Linsley
- R Tirosh
- R Watanabe-Fukunaga
- RM Zinkernagel
- RR Dourmashkin
- S Ceeraz
- S Nagata
- S Sandigursky
- S Stenger
- S Yonehara
- SA Rosenberg
- SC Wei
- SE Stepp
- SL Topalian
- SN Bykovskaya
- T Ahrends
- T Suda
- T Vainio
- T Vanden Berghe
- TW Chang
- V Chiusolo
- W Ax
- W Rosenau
- Y Ishida
- Y Iwai
- Y Shinkai
- Z Eshhar
- Publication venue
- Nat Rev Immunol
- Publication date
- 01/01/2018
- Field of study
After 60 years of intense fundamental research into T cell-mediated cytotoxicity, we have gained a detailed knowledge of the cells involved, specific recognition mechanisms and post-recognition perforin-granzyme-based and FAS-based molecular mechanisms. What could not be anticipated at the outset was how discovery of the mechanisms regulating the activation and function of cytotoxic T cells would lead to new developments in cancer immunotherapy. Given the profound recent interest in therapeutic manipulation of cytotoxic T cell responses, it is an opportune time to look back on the early history of the field. This Timeline describes how the early findings occurred and eventually led to current therapeutic applications
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
- Akpinar HA
- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-GĂłmez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
- Altan-Bonnet N
- Altieri DC
- Alves da Costa C
- Alves S
- Alzaharna MM
- Amadio M
- Amantini C
- Amaral C
- Ambrosio S
- Amer AO
- Ammanathan V
- An Z
- Andersen SU
- Andrabi SA
- Andrade-Silva M
- Andres AM
- Angelini S
- Ann D
- Anozie UC
- Ansari MY
- Antas P
- Antebi A
- AntĂłn Z
- Anwar T
- Apetoh L
- Apostolova N
- Araki T
- Araki Y
- Arasaki K
- Araya J
- AraĂșjo WL
- Arden C
- Arguelles S
- Arias E
- Arikkath J
- Arimoto H
- Ariosa AR
- Armstrong-James D
- Arnauné-Pelloquin L
- Aroca A
- Arroyo DS
- Arsov I
- Artero R
- Arévalo M-A
- Asaro DML
- Aschner M
- Ashrafizadeh M
- Ashur-Fabian O
- Atanasov AG
- Au AK
- Auberger P
- Auner HW
- Aurelian L
- Autelli R
- Avagliano L
- Aveic S
- Aveleira CA
- Avin-Wittenberg T
- Aydin Y
- Ayton S
- Ayyadevara S
- Azzopardi M
- Baba M
- Backer JM
- Backues SK
- Bae D-H
- Bae O-N
- Bae SH
- Baehrecke EH
- Baek A
- Baek S-H
- Baek SH
- Bagetta G
- Bagniewska-Zadworna A
- Bai H
- Bai J
- Bai X
- Bai Y
- Bairagi N
- Baksi S
- Balazadeh S
- Balbi T
- Baldari CT
- Balduini W
- Ballabio A
- Ballester M
- Balzan R
- Bandopadhyay R
- Banerjee S
- Banerjee S
- Bao Y
- Baptista MS
- Baracca A
- Barbati C
- Bargiela A
- BarilĂ D
- Barlow PG
- Barmada SJ
- Barreiro E
- Barreto GE
- Bartek J
- Bartel B
- Bartolome A
- Barve GR
- Basagoudanavar SH
- Bassham DC
- Bast RC
- Basu A
- Batoko H
- Batten I
- Baulieu EE
- Baumgarner BL
- Bayry J
- Beale R
- Beau I
- Beaumatin F
- Bechara LRG
- Beck GR
- Beers MF
- Begun J
- Behl C
- Behrends C
- Behrens GMN
- Bei R
- Bejarano E
- Bel S
- Belaid A
- Belgareh-Touzé N
- Bellarosa C
- Belleudi F
- Bello-Morales R
- BellĂł PĂ©rez M
- Beltran JSDO
- Beltran S
- Benbrook DM
- Bendorius M
- Benitez BA
- Benito-Cuesta I
- Bensalem J
- Berchtold MW
- Berezowska S
- Bergamaschi D
- Bergami M
- Bergmann A
- Berliocchi L
- Berlioz-Torrent C
- Bernard A
- Berthoux L
- Besirli CG
- Besteiro S
- Betin VM
- Beyaert R
- Bezbradica JS
- Bhaskar K
- Bhatia-Kissova I
- Bhattacharya R
- Bhattacharya S
- Bhattacharyya S
- Bhuiyan MS
- Bhutia SK
- Bi L
- Bi X
- Biden TJ
- Bijian K
- Billes VA
- Binart N
- Bincoletto C
- Birgisdottir AB
- Bjorkoy G
- Blanco G
- Blas-Garcia A
- Blasiak J
- Blomgran R
- Blomgren K
- Blum JS
- Boada-Romero E
- Boban M
- Boesze-Battaglia K
- Boeuf P
- Boland B
- Bomont P
- Bonaldo P
- Bonam SR
- Bonfili L
- Bonifacino JS
- Boone BA
- Bootman MD
- Bordi M
- Borner C
- Bornhauser BC
- Borthakur G
- Bosch J
- Bose S
- Botana LM
- Botas J
- Boulanger CM
- Boulton ME
- Bourdenx M
- Bourgeois B
- Bourke NM
- Bousquet G
- Boya P
- Bozhkov PV
- Bozi LHM
- Bozkurt TO
- Brackney DE
- Brand-Saberi B
- Brandts CH
- Braun RJ
- Braus GH
- Bravo-Sagua R
- Bravo-San Pedro JM
- Brest P
- Bringer M-A
- Briones-Herrera A
- Broaddus VC
- Brodersen P
- Brodsky JL
- Brody SL
- Bronson PG
- Bronstein JM
- Brown CN
- Brown RE
- Brum PC
- Brumell JH
- Brunetti-Pierri N
- Bruno D
- Bryson-Richardson RJ
- Bucci C
- Buch S
- Buchan JR
- Buchrieser C
- Buckingham EM
- Budak H
- Budini M
- Bueno M
- Buitrago-Molina LE
- Bultynck G
- Burada F
- Buraschi S
- Burgoyne JR
- BurĂłn MI
- Bustos V
- Butturini E
- Byrd A
- BĂĄnrĂ©ti Ă
- BĂŒttner S
- Cabas I
- Cabrera-Benitez S
- Cadwell K
- Cai J
- Cai L
- Cai Q
- CairĂł M
- Calbet JA
- Caldwell GA
- Caldwell KA
- Call JA
- Calvani R
- Calvo AC
- Calvo-Rubio Barrera M
- Camara NO
- Camonis JH
- Camougrand N
- Campanella M
- Campbell EM
- Campbell-Valois F-X
- Campello S
- Campesi I
- Campos JC
- Camuzard O
- Cancino J
- Candido de Almeida D
- Canesi L
- Caniggia I
- Canonico B
- CantĂ C
- Cao B
- Caraglia M
- Caramés B
- Carchman EH
- Cardenal-Muñoz E
- Cardenas C
- Cardenas L
- Cardoso SM
- Carew JS
- Carle GF
- Carleton G
- Carloni S
- Carmona-Gutierrez D
- Carneiro LA
- Carnevali O
- Carosi JM
- Carra S
- Carrier A
- Carrier L
- Carroll B
- Carter AB
- Carvalho AN
- Casanova M
- Casas C
- Casas J
- Cassioli C
- Castillo EF
- Castillo K
- Castillo-Lluva S
- Castoldi F
- Castori M
- Castro AF
- Castro-Caldas M
- Castro-Hernandez J
- Castro-Obregon S
- Catz SD
- Cavadas C
- Cavaliere F
- Cavallini G
- Cavinato M
- Cayuela ML
- Cebollada Rica P
- Cecarini V
- Cecconi F
- Cechowska-Pasko M
- Cenci S
- Ceperuelo-Mallafré V
- Cerqueira JJ
- Cerutti JM
- Cervia D
- Cetintas VB
- Cetrullo S
- Chae H-J
- Chagin AS
- Chai C-Y
- Chakrabarti G
- Chakrabarti O
- Chakraborty T
- Chakraborty T
- Chami M
- Chamilos G
- Chan DW
- Chan ED
- Chan EYW
- Chan H
- Chan HH
- Chan HYE
- Chan MTV
- Chan YS
- Chandra PK
- Chang C
- Chang C-P
- Chang H-C
- Chang K
- Chao J
- Chapman T
- Charlet-Berguerand N
- Chatterjee S
- Chaube SK
- Chaudhary A
- Chauhan S
- Chaum E
- Checler F
- Cheetham ME
- Chen C-S
- Chen G-C
- Chen J-F
- Chen L
- Chen L
- Chen LL
- Chen M
- Chen M-K
- Chen N
- Chen Q
- Chen R-H
- Chen S
- Chen W
- Chen W
- Chen X
- Chen X-M
- Chen X-W
- Chen Y
- Chen Y
- Chen Y
- Chen Y-G
- Chen Y-J
- Chen Y-Q
- Chen Z
- Chen Z
- Chen Z
- Chen Z-H
- Chen ZJ
- Chen ZS
- Cheng H
- Cheng J
- Cheng S-Y
- Cheng W
- Cheng X
- Cheng X-T
- Cheng Y
- Cheng Z
- Cheong H
- Cheong JK
- Chernyak BV
- Cherry S
- Cheung CFR
- Cheung CHA
- Cheung K-H
- Chevet E
- Chi RJ
- Chiang AKS
- Chiaradonna F
- Chiarelli R
- Chiariello M
- Chica N
- Chiocca S
- Chiong M
- Chiou S-H
- Chiramel AI
- ChiurchiĂč V
- Cho D-H
- Choe S-K
- Choi AMK
- Choi ME
- Choudhury KR
- Chow NS
- Chu CT
- Chua JJE
- Chua JP
- Chung H
- Chung KP
- Chung S
- Chung S-H
- Chung Y-L
- Cianfanelli V
- Ciechomska IA
- Cifuentes M
- Cinque L
- Cirak S
- Cirone M
- Clague MJ
- Clarke R
- Clementi E
- Coccia EM
- Codogno P
- Cohen E
- Cohen MM
- Colasanti T
- Colasuonno F
- Colbert RA
- Colell A
- Coll NS
- Collins MO
- Colombo MI
- ColĂłn-Ramos DA
- Combaret L
- Comincini S
- Cominetti MR
- Consiglio A
- Conte A
- Conti F
- Contu VR
- Cookson MR
- Coombs KM
- Coppens I
- Corasaniti MT
- Cordes N
- Corkery DP
- Cortese K
- Costa MDC
- Costantino S
- Costelli P
- Coto-Montes A
- Crack PJ
- Crespo JL
- Criollo A
- Crippa V
- Cristofani R
- Csizmadia T
- Cuadrado A
- Cui B
- Cui J
- Cui Y
- Cui Y
- Culetto E
- Cumino AC
- Cybulsky AV
- Czaja MJ
- Czuczwar SJ
- D'Adamo S
- D'Amelio M
- D'Arcangelo D
- D'Lugos AC
- D'Orazi G
- da Silva JA
- Dafsari HS
- Dagda RK
- Dagdas Y
- Daglia M
- Dai X
- Dai Y
- Dai Y
- Dal Col J
- Dalhaimer P
- Dalla Valle L
- Dallenga T
- Dalmasso G
- Damme M
- Dando I
- Dantuma NP
- Darling AL
- Das H
- Dasarathy S
- Dasari SK
- Dash S
- Daumke O
- Dauphinee AN
- Davies JS
- Davis RJ
- Davis T
- Dayalan Naidu S
- De Amicis F
- De Bosscher K
- De Felice F
- De Franceschi L
- De Leonibus C
- de Mattos Barbosa MG
- De Meyer GRY
- De Milito A
- De Nunzio C
- De Palma C
- De Santi M
- De Virgilio C
- De Zio D
- Debnath J
- DeBosch BJ
- Decuypere J-P
- Deehan MA
- Deflorian G
- DeGregori J
- Dehay B
- Del Rio G
- Delaney JR
- Delbridge LMD
- Delorme-Axford E
- Delpino MV
- Demarchi F
- Dembitz V
- Demers ND
- Deng H
- Deng Z
- Dengjel J
- Dent P
- Denton D
- DePamphilis ML
- Der CJ
- Deretic V
- Descoteaux A
- Devis L
- Devkota S
- Devuyst O
- Dewson G
- Dharmasivam M
- Dhiman R
- di Bernardo D
- Di Cristina M
- Di Domenico F
- Di Fazio P
- Di Fonzo A
- Di Guardo G
- Di Guglielmo GM
- Di Leo L
- Di Malta C
- Di Nardo A
- Di Rienzo M
- Di Sano F
- Diallinas G
- Diao J
- Diaz-Araya G
- Dickinson JM
- Diederich M
- Dieudé M
- Dikic I
- Ding S
- Ding W-X
- Dini L
- Dinic M
- DiniÄ J
- Dinkova-Kostova AT
- Dionne MS
- Distler JHW
- Diwan A
- Dixon IMC
- Djavaheri-Mergny M
- Dobrinski I
- Dobrovinskaya O
- Dobrowolski R
- Dobson RCJ
- Dokmeci Emre S
- Donadelli M
- Dong B
- Dong X
- Dong XC
- Dong Z
- Dorn Ii GW
- Dotsch V
- Dou H
- Dou J
- Dowaidar M
- Dridi S
- Drucker L
- du Toit A
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- Zimmermann CM
- Ziviani E
- Zoladek T
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- Zorzano A
- Zou W
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- Zuryn S
- Zwerschke W
- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
- Author
- A Berendsen
- A Bird
- A Chmurzynska
- A Deorukhkar
- A El-Osta
- A El-Osta
- A Hinney
- A Jeltsch
- A Link
- A Link
- A Mai
- A Moleres
- A Petronis
- A Plagemann
- A Plagemann
- A Salminen
- A Salminen
- A Santoro
- A Vaquero
- AA Bertelli
- AA Houde
- AA Jackson
- AE Teschendorff
- AG Ladurner
- AL Teh
- AN Thorburn
- AP Bracken
- AT Hauser
- AT Paul
- AV Gasper
- AV Shirodkar
- B Delage
- B Delatte
- B Maher
- B Perillo
- BB Aggarwal
- BB Aggarwal
- BC Christensen
- BP Hubbard
- BT Kawasaki
- BT Seet
- C Beaudoin
- C Blanpain
- C Franceschi
- C Gallou-Kabani
- C Gallou-Kabani
- C Gerhauser
- C Heiss
- C Jin
- C Kontogiorgis
- C Ling
- C Lu
- C LĂłpez-OtĂn
- C Manach
- C Manach
- C Manach
- C Manach
- C Roadmap Epigenomics
- CA Cooney
- CC Li
- CE Cho
- CH Arrowsmith
- CL DoAmaral
- CM Guerrero-Bosagna
- CM Ulrich
- CP Wong
- CS Rosenfeld
- D Baylis
- D Brasacchio
- D Feng
- D Holoch
- D Khanna
- D MartĂnez
- D Milenkovic
- D MĂŒnch
- D Pons
- D Schubeler
- D Xia
- DA Schwartz
- DC Dolinoy
- DC Dolinoy
- DC Wallace
- DC Wallace
- DF Romagnolo
- DH Lee
- DJ Barker
- DJ Lowsky
- DM Ruden
- DM Ruden
- DS Paul
- E Barrajon-Catalan
- E Cevenini
- E Kampen van
- E Nilsson
- E Whitelaw
- EJ McAllister
- EJ Radford
- EJ Topol
- EL Greer
- EM Straten van
- EN Bermingham
- EP Chiang
- F Crea
- F Folmer
- F Santa De
- F Sheedfar
- FH Einstein
- FI Milagro
- FI Milagro
- G Almouzni
- G Bistulfi
- G Bonuccelli
- G Chiva-Blanch
- G Hannum
- G Kaati
- G Lund
- G Lund
- G Toperoff
- G Williamson
- GC Burdge
- GC Burdge
- GC Burdge
- GL Gabor Miklos
- H Heyn
- H Heyn
- H Kirchner
- H Kirk
- H Kuniyasu
- H Lehnen
- H Sies
- I Cascorbi
- I Dunham
- IC Weaver
- IP Pogribny
- J Bossche Van den
- J Chang
- J Ernst
- J Ernst
- J Feser
- J Huang
- J Joven
- J Lewandowska
- J Luo
- J Mill
- J Oh
- J Zhao
- J Zhou
- J Zhu
- JA Baur
- JA Kreiling
- JA Law
- JA Menendez
- JC Rathmell
- JE Castillo-Fernandez
- JE Cropley
- JG Wood
- JG Wood
- JJ Waterfall
- JL Rios
- JM Kim
- JM Ordovas
- JR Whittle
- JR Zierath
- JS You
- K Blaschke
- K Falkenberg
- K Ghoshal
- K Helin
- K Szarc vel Szic
- K Tateishi
- KA Lillycrop
- KB Adamo
- KE Wellen
- KJ Dick
- KM Godfrey
- KS Vel Szic
- KT Howitz
- KV Morris
- L Altucci
- L Attig
- L Bouchard
- L Chouliaras
- L Wang
- L Yang
- LE Wu
- LF Gaal Van
- LH Lumey
- LM Villeneuve
- M Christodoulou
- M Esteller
- M Esteller
- M Fang
- M Fuente De la
- M Ivanov
- M Ivanov
- M Ivanov
- M Kamakura
- M Karin
- M Kim
- M Loeffler
- M Miceli
- M Pembrey
- M Susiarjo
- M Wossidlo
- MA Hanson
- MA Reddy
- MA Surani
- MB Vandegehuchte
- MC Oberstadt
- MD Anway
- MD Anway
- ME Blewitt
- ME Figueroa
- MF Fraga
- MF Fraga
- MG Mirisola
- MJ Hitchler
- MJ Hitchler
- ML Groote de
- MM Bellet
- MM Niedzwiecki
- MN Ndlovu
- MP Turunen
- MS Denison
- N Dijsselbloem
- N McCarthy
- NA Kittan
- NA Youngson
- NC Chen
- ND Fisher
- NE Simpson
- O Aguilera
- P Anand
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- P Chi
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- P Hajkova
- P Hunter
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- PA Jones
- PA Jones
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- PC Tsai
- PD Darbre
- PD Gluckman
- PD Gluckman
- PS Ward
- PW Franks
- Q Tan
- R Barouki
- R Barres
- R Chowdhury
- R Deplus
- R Karemaker
- R Kogo
- R Kucharski
- R Liu
- R Maleszka
- R Teperino
- R Yin
- R Zamora-Ros
- RA Waterland
- RA Waterland
- RA Waterland
- RC Painter
- RD Shytle
- RJ Colman
- RJ Colman
- RJ Wierda
- RL Jirtle
- RL Miller
- RL Schilsky
- RP Arasaradnam
- RR Newbold
- S Assis De
- S Chong
- S Foret
- S Foret
- S Guil
- S Han
- S Imai
- S Katada
- S Maegawa
- S Zaina
- SA Langie
- SA Langie
- SH Ley
- SI Grivennikov
- SK Huang
- SM Langevin
- SW Waldo
- T Dao
- T Eisenberg
- T Eisenberg
- T Roseboom
- T Suzuki
- TA Dayeh
- TA Manolio
- TC Rideout
- TJ Maures
- TJ Wigle
- TM Badger
- TM Murphy
- UE Martinez-Outschoorn
- V Boonsanay
- V Davalos
- V Desgagne
- V Pazienza
- V Sollars
- V Valinluck
- V Valinluck
- VA DeWoskin
- VA Herzog
- VJ Peschansky
- W Vanden Berghe
- W Vanden Berghe
- W Vanden Berghe
- WG Kaelin Jr
- X Guo
- X Li
- X Liu
- X Wang
- X Wang
- X Yang
- XB Zhong
- Y Hu
- Y Jiang
- Y Li
- Y Li
- Y Liu
- YG Zheng
- YJ Surh
- ZA Kaminsky
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Experimental evidence of the formation of a new chemical phase in a power ramped UO2 nuclear fuel
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Regulation of the acid-labile subunit in sustained endotoxemia
- Author
- Publication venue
- 'American Physiological Society'
- Publication date
- Field of study
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