Declining Prices in the Sequential Dutch Flower Auction of Roses

sequential auctions;declining prices;buyer's option

Parental psychopathology and the early developing child: The Generation R Study

Up to now research tradition particularly focused on the influence of maternal psychopathology on the early developing infant. There are two main reasons to focus on paternal psychopathology during pregnancy. Firstly, fathers contribute 50% of their children’s genes and depression and anxiety are highly heritable in infants. Secondly, paternal psychopathology can be an important confounder in associations between maternal psychopathology during pregnancy and the developing infant. This study was embedded in the Generation R Study, a prospective multiethnic population-based study on growth, development and health of children followed from early fetal life. This thesis aimed at extending the existing knowledge on transgenerational aspects of common psychiatric disorders. The main findings were: 1. During pregnancy mothers had much higher levels of psychopathology compared to fathers. Maternal and paternal psychopathology were significantly correlated (.32). Ethnicity explained most of the variance of the investigated factors on all symptom scales of the BSI. Participants with other ethnic backgrounds had higher psychopathology scores than native Dutch, even after adjustment for age and educational level. 2. Maternal depression – and not anxiety – seems to be associated with lower birth weight of the child, even after adjustment for parental birth weight and other confounders. 3. Maternal and paternal depression during pregnancy did influence their children’s behaviour in different ways. Both maternal and paternal depression during pregnancy were independently, though differently, related to excessive infant crying at 2 months. Maternal depression during pregnancy was independently associated with recovery from distress and sadness in 6-month-old girls, and to distress to limitations in 6-month-old boys. Paternal depression during pregnancy was not associated with behaviour of 6-month-old girls, while it was independently associated with fear in 6-month-old boys

Interventions to treat mental disorders during pregnancy: A systematic review and multiple treatment meta-Analysis

Background For women suffering from an antepartum mental disorder (AMD), there is lack of evidencebased treatment algorithms due to the complicated risk-benefit analysis for both mother and unborn child. We aimed to provide a comprehensive overview of pharmacological and nonpharmacological interventions to treat AMD and performed a meta-Analysis of the estimated treatment effect on the psychiatric symptoms during pregnancy. Methods MedLine, PsycINFO and Embase databases were searched by two independent reviewers for clinical trials with a control condition on treatment of women with AMD, i.e. major depressive (MDD), anxiety, psychotic, eating, somatoform and personality disorders. We inventoried the effect of the treatment, i.e. decrease of psychiatric symptoms at the end of the treatment or postpartum. We adhered to the PRISMA-protocol. Findings Twenty-nine trials were found involving 2779 patients. Trials studied patients with depressive disorders (k = 28), and anxiety disorders (k = 1). No pharmacological trials were detected. A form of psychotherapy, like Cognitive Behavioural Therapy (g = -0.61; 95%CI:- 0.73 to -0.49, I2 = 0%; k = 7) or Interpersonal Psychotherapy (g = -0.67; 95%CI:-1.27 to -0.07; I2 = 79%; k = 4), holds robust benefit for pregnant women with MDD. Body-oriented interventions (g = -0.43; 95%CI:-0.61 to -0.25; I2 = 17%; k = 7) and acupuncture (g = -0.43; 95%CI:-0.80 to -0.06; I2 = 0%; k = 2) showed medium sized reduction of depressive symptoms. Bright light therapy (g = -0.59; 95%CI:-1.25 to 0.06; I2 = 0%; k = 2), and food supplements (g = -0.51; 95%CI:-1.02 to 0.01; I2 = 20%; k = 3) did not show significant treatment effects. One study was found on Integrative Collaborative Care

Assessment of nutritional status in haemodialysis patients using PG-SGA and handgrip strength

In this cross-sectional study, we primarily aimed to assess prevalence of malnutrition by the Patient Generated Subjective Global Assessment (PGSGA), and muscle strength in haemodialysis patients. Second, we explored to which extent these patients are able to complete the patient component of the PG-SGA, aka PG-SGA Short Form (SF) (weight, intake, symptoms, activities/functioning) independently

Successful five-item triage for the broad spectrum of mental disorders in pregnancy - A validation study

Background: Mental disorders are prevalent during pregnancy, affecting 10% of women worldwide. To improve triage of a broad spectrum of mental disorders, we investigated the decision impact validity of: 1) a short set of currently used psychiatric triage items, 2) this set with the inclusion of some more specific psychiatric items (intermediate set), 3) this new set with the addition of the 10-item Edinburgh Depression Scale (extended set), and 4) the final set with the addition of common psychosocial co-predictors (comprehensive set). Methods: This was a validation study including 330 urban pregnant women. Women completed a questionnaire including 20 psychiatric and 10 psychosocial items. Psychiatric diagnosis (gold standard) was obtained through Structured Clinical Interviews of DSM-IV axis I and II disorders (SCID-I and II). The outcome measure of our anal

Peripartum Cardiomyopathy as a Part of Familial Dilated Cardiomyopathy

BACKGROUND-: Anecdotal cases of familial clustering of peripartum cardiomyopathy (PPCM) and familial occurrences of PPCM and idiopathic dilated cardiomyopathy (DCM) together have been observed, suggesting that genetic factors play a role in the pathogenesis of PPCM. We hypothesized that some cases of PPCM are part of the spectrum of familial DCM, presenting in the peripartum period. METHODS AND RESULTS-: We reviewed our database of 90 DCM families, focusing specifically on the presence of PPCM patients. Then, in a reverse approach, we reviewed 10 PPCM patients seen in our clinic since the early 1990s and performed cardiological screening of the first-degree relatives of 3 PPCM patients who did not show a full recovery. Finally, we analyzed the genes known to be most commonly involved in DCM in the PPCM patients. We identified a substantial number (5 of 90, 6%) of DCM families with PPCM patients. Second, cardiological screening of first-degree relatives of 3 PPCM patients who did not show full recovery revealed undiagnosed DCM in all 3 families. Finally, genetic analyses revealed a mutation (c.149A>G, p.Gln50Arg) in the gene encoding cardiac troponin C (TNNC1) segregating with disease in a DCM family with a member with PPCM, supporting the genetic nature of disease in this case. CONCLUSIONS-: Our findings strongly suggest that a subset of PPCM is an initial manifestation of familial DCM. This may have important implications for cardiological screening in such families

Marktkansen voor etnisch voedsel en etnische diensten

De bevolkingssamenstelling van de Nederlandse steden is afgelopen jaren sterk veranderd. De stedelijke vraag naar producten en diensten van het platteland is ook sterk veranderd. Uit de quick scan is gebleken dat de 'ethnic food & services' een belangrijk onderdeel vormen van de nieuwe vraag. Dit dient niet alleen ten behoeve van de nichemarkt van ethnic food & services maar kan tegelijkertijd als een strategisch middel ingezet worden om de algemene stadplattelandsrelaties aan te halen, uit te breiden en te verbetere

The prevalence and correlates of self-harm in pregnant women with psychotic disorder and bipolar disorder

Women with severe mental illness are at increased risk of suicide in the perinatal period, and these suicides are often preceded by self-harm, but little is known about self-harm and its correlates in this population. This study aimed to investigate the prevalence of suicidal ideation and self-harm, and its correlates, in women with psychotic disorders and bipolar disorder during pregnancy. Historical cohort study using de-identified secondary mental healthcare records linked with national maternity data. Women pregnant from 2007 to 2011, with ICD-10 diagnoses of schizophrenia and related disorders, bipolar disorder or other affective psychoses were identified. Data were extracted from structured fields, natural language processing applications and free text. Logistic regression was used to examine the correlates of self-harm in pregnancy. Of 420 women, 103 (24.5 %) had a record of suicidal ideation during the first index pregnancy, with self-harm recorded in 33 (7.9 %). Self-harm was independently associated with younger age (adjusted odds ratio (aOR) 0.91, 95 % CI 0.85–0.98), self-harm in the previous 2 years (aOR 2.55; 1.05–6.50) and smoking (aOR 3.64; 1.30–10.19). A higher prevalence of self-harm was observed in women with non-affective psychosis, those who discontinued or switched medication and in women on no medication at the start of pregnancy, but these findings were not statistically significant in multivariable analyses. Suicidal thoughts and self-harm occur in a significant proportion of pregnant women with severe mental illness, particularly younger women and those with a history of self-harm; these women need particularly close monitoring for suicidality

Amounts of litter fall in some pine forests in a European transect, in particular Scots pine.

Pine litter fall data, mainly needle litter, were available for 64 plots in a transect from the Arctic Circle in Fennoscandia (41 plots) to southern Spain (22 further plots in continental Europe) and one in the American Midwest). Data originated from a total of eight pine species. Regressions were calculated mainly for needle litter fall and to some extent for total litter fall. We obtained a highly significant linear relationship for needle litter fall and latitude (R 2adj = 0.285; n = 58; P < 0.001) when using needle litter fall data from all pine species. Combining sites in the boreal and Atlantic climates gave an R2 adj of 0.732 with n = 45 (P < 0.001). A multiple linear relationship using stand age, latitude and basal area was highly significant and gave an R2adj value of 0.412 (n = 54; P < 0.001). For the amount of Scots pine needle litter in Fennoscandia, the best simple linear relationships were obtained with site index (H 100) (R2 adj = 0.349), latitude (R2adj = 0.331) and basal area (R2adj = 0.324) as predictor variables, whereas the regressions on altitude and stand age were significant only with P < 0.01. An X2 function for stand age improved the relationship with age to R2adj = 0.243. Multiple regression relationships for Fennoscandia between needle litter fall and latitude plus basal area and that to latitude plus basal area plus age were highly significant (R2adj = 0.605 and 0.661, respectively, with n = 41). In a stepwise procedure using data from the same sites, combinations of the factors latitude, site index, basal area and stand age could explain as much as 78 % of the needle litter fall. For total litter fall as measured by the same method as needle litter we related data from 32 sites to that of needle litter fall and obtained highly significant relationships indicating that needle litter fall may be used as an index for total litter fall. © 1999 Inra/Éditions scientifiques et médicales Elsevier SAS.Chute de litière dans quelques forêts de pins, en particulier du Pin sylvestre, le long d'un transect européen. Les données de chute de litière, essentiellement des chutes d'aiguilles, étaient disponibles pour 64 sites le long d'un transect depuis le cercle polaire en Scandinavie (41 sites) jusqu'au Sud de l'Espagne (22 sites supplémentaires en Europe continentale) et un site dans le midouest américain. Les données proviennent de huit espèces de Pin. Des régressions ont été calculées principalement pour la chute d'aiguilles et dans certains cas pour la chute totale de litière. Il existe une relation linéaire hautement significative entre la chute des aiguilles et la latitude (R2adj = 0.285 ; n = 58; p < 0,001) lorsque l'ensemble des données pour toutes les espèces sont utilisées. La combinaisons des sites en climat boréal et atlantique donne un R2adj de 0.732 pour n = 45 (p < 0,001). Une relation linéaire multiple, utilisant l'âge du peuplement, la latitude et la surface terrière est hautement significative et donne un R 2∼ de 0.412 (n = 54; p < 0.001). La meilleure relation linéaire, pour les retours d'aiguilles chez le Pin sylvestre en Scandinavie a été obtenue en utilisant comme variables prédictives l'indice de fertilité stationnelle « H 100 » (R2 adj = 0.349), la latitude (Radj = 0331), et la surface terrière (R2adj = 0.324 ; alors que la régression sur les variables altitudes et âge des peuplements n'était significative seulement à p < 0,01. Une fonction X2 pour l'âge du peuplement améliore la relation avec l'âge, R2adj = 0,243. Les relations multiples entre la chute des aiguilles et la latitude associée à la surface terrière et celle associée à la surface terrière plus l'âge, pour les sites Scandinaves, sont hautement significatives (R2 adj = 0,605 et R2adj = 0,661, respectivement, avec n = 41 ). La procédure de régression progressive sur les données des mêmes sites, combinaisons des variables latitude, indice de fertilité, surface terrière et âge du peuplement permet d'expliquer 78 % de la variation de la chute des aiguilles. Des relations hautement significatives ont été calculées sur les données des retours totaux de litière, utilisant la même méthodologie sur 32 des sites. Elles démontrent que la quantité des chutes des seules aiguilles peut être utilisée comme indice pour la chute totale de la litière. © 1999 Inra/Éditions scientifiques et médicales Elsevier SAS