Who voted for Perón? Essays on the Argentine mid-20th century Presidential Elections

Programa de Doctorado en Historia Económica por la Universidad Carlos III de Madrid y la Universidad de BarcelonaPresidente: María del Mar Rubio Varas.- Secretario: Francisco Herreros.- Vocal: Sebastián Lavezzolo Pére

The Battle of Konotop 1659. Exploring alternatives in East European History

The battle that took place near Konotop in late June 1659 was a continuation of the Muscovite-Cossack war, which began in the fall of 1658, soon after the signing of the Union of Hadiach. Cossack and Tatar detachments trapped a significant portion of the Muscovite army, leading to enormous Russian losses. The unprecedented defeat of the previously invincible forces caused panic in Russia, but Muscovites’ capacity to turn defeat into political victory, and the fratricidal struggle in Ukraine, known as the “Ruin”, left most of the Cossack lands on the Right Bankof the Dnieper uninhabitable.Konotop is a classic example of a battle won, but a war lost. Mariusz Robert Drozdowski, Ksenia Konstantynenko, Piotr Kroll, Serhii Plokhy, Oleg Rumyantsev, Natalia Yakovenko and Tatjana Yakovleva-Tairova, the authors of this collection, hail from Poland, Italy, USA, Ukraine and Russia. They consider the military, political, social, and cultural context of the battle and also investigate its treatement in historical and literarywritings from the early modern era to the present. They approach their topic from the point of view of various disciplines, traditions, and schools of thought. Their essays expand our understanding of the battle, its outcome and legacy in unexpected and historiographically productive ways

Gadolinium substitution effect on the thermomagnetic properties of Ni ferrite ferrofluids

Versión enviada del artículo; finalmente publicado en: Jacobo, S. E., Arana, M. y Bercoff, P. G. (2016). Gadolinium substitution effect on the thermomagnetic properties of Ni ferrite ferrofluids. Journal of Magnetism and Magnetic Materials, 415, 30-34. https://doi.org/10.1016/j.jmmm.2015.11.047Fil: Jacobo, Silvia Elena. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina.Fil: Jacobo, Silvia Elena. Universidad de Buenos Aires. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; Argentina.Fil: Jacobo, Silvia Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; Argentina.Fil: Arana, Mercedes. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía, Física y Computación; Argentina.Fil: Arana, Mercedes. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina.Fil: Arana, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina.Fil: Bercoff, Paula Gabriela. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía, Física y Computación; Argentina.Fil: Bercoff, Paula Gabriela. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina.Fil: Bercoff, Paula Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina.This work is focused on the characterization of Ni-ferrite nanocrystals and their subsequent doping with Gd, in an attempt to explore Gd inclusion in the thermomagnetic properties of prepared ferrofluids. Spinel ferritesNiFe2O4, and NiFe1.88Gd0.12O4 were prepared by the auto-combustion method. The substituted sample is obtained with a small amount of Gd inclusion and the excess appears as GdFeO3. The smallest nanoparticles of both samples were properly coated and dispersed in kerosene. Thermal conductivities of the produced ferrofluids were measured at 25 °C in a magnetic field. There is a significant enhancement in thermal conductivity of the ferrofluid prepared with NiGd ferrite with respect to the one with Ni ferrite, in presence of a magnetic field. This effect is directly related to the well-known magnetocaloric effect of Gd.info:eu-repo/semantics/submittedVersionFil: Jacobo, Silvia Elena. Universidad de Buenos Aires. Facultad de Ingeniería; Argentina.Fil: Jacobo, Silvia Elena. Universidad de Buenos Aires. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; Argentina.Fil: Jacobo, Silvia Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; Argentina.Fil: Arana, Mercedes. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía, Física y Computación; Argentina.Fil: Arana, Mercedes. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina.Fil: Arana, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina.Fil: Bercoff, Paula Gabriela. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía, Física y Computación; Argentina.Fil: Bercoff, Paula Gabriela. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina.Fil: Bercoff, Paula Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina.Cerámico

Duplicability of self-interacting human genes

BACKGROUND There is increasing interest in the evolution of protein-protein interactions because this should ultimately be informative of the patterns of evolution of new protein functions within the cell. One model proposes that the evolution of new protein-protein interactions and protein complexes proceeds through the duplication of self-interacting genes. This model is supported by data from yeast. We examined the relationship between gene duplication and self-interaction in the human genome. RESULTS We investigated the patterns of self-interaction and duplication among 34808 interactions encoded by 8881 human genes, and show that self-interacting proteins are encoded by genes with higher duplicability than genes whose proteins lack this type of interaction. We show that this result is robust against the system used to define duplicate genes. Finally we compared the presence of self-interactions amongst proteins whose genes have duplicated either through whole-genome duplication (WGD) or small-scale duplication (SSD), and show that the former tend to have more interactions in general. After controlling for age differences between the two sets of duplicates this result can be explained by the time since the gene duplication. CONCLUSIONS Genes encoding self-interacting proteins tend to have higher duplicability than proteins lacking self-interactions. Moreover these duplicate genes have more often arisen through whole-genome rather than small-scale duplication. Finally, self-interacting WGD genes tend to have more interaction partners in general in the PIN, which can be explained by their overall greater age. This work adds to our growing knowledge of the importance of contextual factors in gene duplicability.At the time of publication the author Pérez-Bercoff was affiliated with Smurfit Institute of Genetics, University of Dublin, Trinity College, Dublin

Transient Anomaly Imaging in Visco-Elastic Media Obeying a Frequency Power-Law

In this work, we consider the problem of reconstructing a small anomaly in a viscoelastic medium from wave-field measurements. We choose Szabo's model to describe the viscoelastic properties of the medium. Expressing the ideal elastic field without any viscous effect in terms of the measured field in a viscous medium, we generalize the imaging procedures, such as time reversal, Kirchhoff Imaging and Back propagation, for an ideal medium to detect an anomaly in a visco-elastic medium from wave-field measurements

Whole CMV proteome pattern recognition analysis after HSCT identifies unique epitope targets associated with the CMV status

Cytomegalovirus (CMV) infection represents a vital complication after Hematopoietic Stem Cell Transplantation (HSCT). We screened the entire CMV proteome to visualize the humoral target epitope-focus profile in serum after HSCT. IgG profiling from four patient groups (donor and/or recipient +/- for CMV) was performed at 6, 12 and 24 months after HSCT using microarray slides containing 17174 of 15mer-peptides overlapping by 4 aa covering 214 proteins from CMV. Data were analyzed using maSigPro, PAM and the 'exclusive recognition analysis (ERA)' to identify unique CMV epitope responses for each patient group. The 'exclusive recognition analysis' of serum epitope patterns segregated best 12 months after HSCT for the D+/R+ group (versus D-/R-). Epitopes were derived from UL123 (IE1), UL99 (pp28), UL32 (pp150), this changed at 24 months to 2 strongly recognized peptides provided from UL123 and UL100. Strongly (IgG) recognized CMV targets elicited also robust cytokine production in T-cells from patients after HSCT defined by intracellular cytokine staining (IL-2, TNF, IFN and IL-17). High-content peptide microarrays allow epitope profiling of entire viral proteomes; this approach can be useful to map relevant targets for diagnostics and therapy in patients with well defined clinical endpoints. Peptide microarray analysis visualizes the breadth of B-cell immune reconstitution after HSCT and provides a useful tool to gauge immune reconstitution.The work has been funded by ALF (Arbetslivfonden) to M.M. and P.L. funds from Karolinska Institutet and Vinnova, Sweden to M.M

Psiquiatría : Sus aportes a la formación del futuro médico

S/RLa Psiquiatría, una de las especialidades de las Ciencias médicas, posee un importante bagaje de conocimientos para aportar al recorrido académico en la formación del futuro médico. Estos conocimientos no se limitan a la clínica de las patologías que le competen a su territorio, sino también abarcan lo atinente a la constitución del sujeto y del aparato psíquico. Entendemos que sin esta base, que nos acerca al proceso salud - enfermedad -trascendiendo su linealidad fisiopatológica-, se dificulta el ejercicio de la profesión, como así también la aproximación a una lectura de otro orden sobre los padecimientos, tanto físicos como psíquicos.Fil: Bercoff, Elena. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Rosario; Argentin

A Conserved Mammalian Protein Interaction Network

Physical interactions between proteins mediate a variety of biological functions, including signal transduction, physical structuring of the cell and regulation. While extensive catalogs of such interactions are known from model organisms, their evolutionary histories are difficult to study given the lack of interaction data from phylogenetic outgroups. Using phylogenomic approaches, we infer a upper bound on the time of origin for a large set of human protein-protein interactions, showing that most such interactions appear relatively ancient, dating no later than the radiation of placental mammals. By analyzing paired alignments of orthologous and putatively interacting protein-coding genes from eight mammals, we find evidence for weak but significant co-evolution, as measured by relative selective constraint, between pairs of genes with interacting proteins. However, we find no strong evidence for shared instances of directional selection within an interacting pair. Finally, we use a network approach to show that the distribution of selective constraint across the protein interaction network is non-random, with a clear tendency for interacting proteins to share similar selective constraints. Collectively, the results suggest that, on the whole, protein interactions in mammals are under selective constraint, presumably due to their functional roles.A˚.P.B. is supported by Ga˚lo¨stiftelsen Stipendium fo¨r ho¨gre utlandsstudier. C.M.H. is supported by a National Library of Medicine Biomedical and Health Informatics Training Fellowship [LM007089-19]. G.C.C. is supported by the Reproductive Biology Group of the Food for the 21st Century program at the University of Missouri. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript