Learning about climate change in, with and through art

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ART FOR CHANGE: Transformative learning and youth empowerment in a changing climate

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Decolonizing transformations through ‘right relations’

Climate change has been conceptualized as a form and a product of colonization. In this perspective, it becomes important to base climate change adaptation and transformation efforts on decolonizing practices and imaginaries. A central aspect of decolonization is contained in the Indigenous conceptualization of relationality. Exploring how decolonization and relationality might form the foundation for transformations research, we engage with the concept of ‘right relations’. In the context of this inquiry, we take ‘right relations’ to mean an obligation to live up to the responsibilities involved when taking part in a relationship—be it to other humans, other species, the land or the climate. We begin the paper by bringing together the literature on climate change adaptation, transformation and decolonization to show their interconnections and emphasize the need to engage with all three when talking about sustainability. Second, we invoke the idea of ‘right relations’ to address how non-Indigenous transformation researchers can further the process of decolonization as part of their research. Third, we offer insights from our own research experience with narrative practices to help exemplify how transformation researchers in all disciplines might embody ‘right relations’ centered around four characteristics: listening deeply, self-reflexivity, creating space and being in action. Embodying ‘right relations’ is a continuous process of becoming with no end point, and we do not wish to suggest that we hold the answers. Instead, we reflect on our role in this process and hope for these words to open a dialogue about how we might move towards a ‘decolonized humanity’. We suggest that willingness to be affected and altered by the process of reciprocal collaborations is key to imagining decolonial ways of being and that this in turn can be a powerful manner of generating equitable and sustainable transformations.info:eu-repo/semantics/publishedVersio

Optimal strategies for marine wildlife tourism in small islands

Tese de Doutoramento, Ciências Económicas e Empresariais (especialidade de Economia), 18 de Junho de 2015, Universidade dos AçoresO arquipélago dos Açores é um destino emergente para o turismo de observação de vida marinha, oferecendo a possibilidade de mergulho com espécies emblemáticas, nomeadamente o tubarão azul e jamanta, e de observação de uma elevada diversidade de espécies de cetáceos. Este estudo explora as dimensões socias da observação de cetáceos e do mergulho, procurando contribuir para o desenvolvimento de estratégias de gestão sustentável destas actividades. Compreender e explorar a variabilidade existente nas atitudes e perfis dos consumidores destes produtos turísticos pode ajudar os decisores e operadores locais a avaliar o potencial de desenvolvimento futuro deste mercado, bem como a desenhar melhores práticas e políticas de gestão. A investigação sobre estas temáticas, prevendo o comportamento dos utilizadores recreativos e de possíveis quebras na qualidade do destino turístico, pode contribuir significativamente para a melhoria das medidas de gestão. Este estudo aplica métodos de investigação qualitativos e quantitativos, avaliando os dados obtidos através de modelos conceptuais de turismo de observação de vida selvagem marinha. O modelo de Duffus e Dearden (1990) relativo às actividades recreativas não consumistas, orientadas para a vida selvagem constitui o principal quadro conceptual desta investigação. […].ABSTRACT: The Azores archipelago is an emerging marine wildlife tourism destination featuring diving with large iconic species including blue sharks and manta rays and whale watching with a high diversity of cetacean species. This study explores human dimensions of whale watching and diving as an input for sustainable management strategies for these activities. Understanding and exploring the variability in attitudes and profiles of marine wildlife users can help decision makers and local operators assess the potential for future development of this market as well as design better management practices and policies. Research on these subjects has the potential to enhance management through predicting the behavior of recreationists and forecasting possible quality declines of a destination. This study applies both qualitative and quantitative research methods and evaluates the obtained data with the help of conceptual marine wildlife tourism models. Duffus and Dearden’s (1990) model of non-consumptive wildlife-oriented recreation provides the main conceptual framework for this research. […].This PhD research (DB/75928/2011) is funded by Fundação para a Ciência e Technologia

Creative, embodied practices, and the potentialities for sustainability transformations

This paper argues for an integrative approach to sustainability transformations, one that reconnects body and mind, that fuses art and science and that integrates diverse forms of knowledge in an open, collaborative and creative way. It responds to scholarship emphasizing the importance of connecting disparate ways of knowing, including scientific, artistic, embodied and local knowledges to better understand environmental change and to foster community resilience and engagement. This paper draws on the experience of an arts-based project in Lisbon, Portugal, and explores embodied and performative practices and their potential for climate change transformations. It puts forward and enlivens an example, where such forms of engaging communities can provide new insight into how equitable, just and sustainable transformations can come about. The process involved a series of interactive workshops with diverse arts-based methods and embodied practices to create performative material. From this process, a space emerged for the creation of meaning about climate change. Three key elements stood out in this process as being potentially important for the emergence of meaning-making and for understanding the impact of the project: the use of metaphors, embedding the project locally, and the use of creative, embodied practices. This furthers research, suggesting that the arts can play a critical role in engaging people with new perspectives on climate change and sustainability issues by offering opportunities for critical reflection and providing spaces for creative imagination and experimentation. Such processes may be important for contributing to the changes needed to realize transformations to sustainability.info:eu-repo/semantics/publishedVersio

How vulnerable are cetaceans to climate change? Developing and testing a new index

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Cardiovascular magnetic resonance risk stratification in patients with clinically suspected myocarditis

BACKGROUND: The diagnosis of myocarditis is challenging due to its varying clinical presentation. Since myocarditis can be associated with significant 5-year mortality, and postmortem data show myocarditis in almost 10% of all adults suffering sudden cardiac death, individual risk stratification for patients with suspected myocarditis is of great clinical interest. We sought to demonstrate that patients with clinically suspected myocarditis and a normal cardiovascular magnetic resonance (CMR) according to our definition have a good prognosis, independent of their clinical symptoms and other findings. METHODS: Prospective clinical long-term follow-up of consecutive patients undergoing CMR for work-up of clinically suspected myocarditis at our institution in 2007-2008. RESULTS: Follow-up was available for n = 405 patients (all-comers, 54.8% inpatients, 38% outpatient referrals from cardiologists). Median follow-up time was 1591 days. CMR diagnosis was “myocarditis” in 28.8%, “normal” in 55.6% and “other pathology” in 15.6%. Normal CMR was defined as normal left ventricular (LV) volumes and normal left ventricular ejection fraction (LV-EF) in the absence of late Gadolinium Enhancement (LGE). The overall mortality was 3.2%. There were seven cardiac deaths during follow-up, in addition one aborted SCD and two patients had appropriate internal cardioverter defibrillator (ICD) shocks – all of these occurred in patients with abnormal CMR. Kaplan-Meier analysis with log-rank test showed significant difference for major adverse cardiac events (cardiac death, sudden cardiac death (SCD), ICD discharge, aborted SCD) between patients with normal and abnormal CMR (p = 0.0003). CONCLUSION: In our unselected population of consecutive patients referred for CMR work-up of clinically suspected myocarditis, patients with normal CMR have a good prognosis independent of their clinical symptoms and other findings

Epstein–Barr virus BRLF1 inhibits transcription of IRF3 and IRF7 and suppresses induction of interferon-β

Activation of interferon regulatory factors (IRFs) 3 and 7 is essential for the induction of Type I interferons (IFN) and innate antiviral responses, and herpesviruses have evolved mechanisms to evade such responses. We previously reported that Epstein-Barr Virus BZLF1, an immediate-early (IE) protein, inhibits the function of IRF7, but the role of BRLF1, the other IE transactivator, in IRF regulation has not been examined. We now show that BRLF1 expression decreased induction of IFN-β, and reduced expression of IRF3 and IRF7; effects were dependent on N- and C-terminal regions of BRLF1 and its nuclear localization signal. Endogenous IRF3 and IRF7 RNA and protein levels were also decreased during cytolytic EBV infection. Finally, production of IFN-β was decreased during lytic EBV infection and was associated with increased susceptibility to superinfection with Sendai virus. These data suggest a new role for BRLF1 in the ability of to evade host innate immune responses

Epstein–Barr virus BRLF1 inhibits transcription of IRF3 and IRF7 and suppresses induction of interferon-β

Activation of interferon regulatory factors (IRFs) 3 and 7 is essential for the induction of Type I interferons (IFN) and innate antiviral responses, and herpesviruses have evolved mechanisms to evade such responses. We previously reported that Epstein-Barr Virus BZLF1, an immediate-early (IE) protein, inhibits the function of IRF7, but the role of BRLF1, the other IE transactivator, in IRF regulation has not been examined. We now show that BRLF1 expression decreased induction of IFN-β, and reduced expression of IRF3 and IRF7; effects were dependent on N- and C-terminal regions of BRLF1 and its nuclear localization signal. Endogenous IRF3 and IRF7 RNA and protein levels were also decreased during cytolytic EBV infection. Finally, production of IFN-β was decreased during lytic EBV infection and was associated with increased susceptibility to superinfection with Sendai virus. These data suggest a new role for BRLF1 in the ability of to evade host innate immune responses

KSHV LANA and EBV LMP1 induce the expression of UCH-L1 following viral transformation

Ubiquitin C-terminal Hydrolase L1 (UCH-L1) has oncogenic properties and is highly expressed during malignancies. We recently documented that Epstein-Barr virus (EBV) infection induces uch-l1 expression. Here we show that Kaposi's Sarcoma-associated herpesvirus (KSHV) infection induced UCH-L1 expression, via cooperation of KSHV Latency-Associated Nuclear Antigen (LANA) and RBP-Jκ and activation of the uch-l1 promoter. UCH-L1 expression was also increased in Primary Effusion Lymphoma (PEL) cells co-infected with KSHV and EBV compared with PEL cells infected only with KSHV, suggesting EBV augments the effect of LANA on uch-l1. EBV latent membrane protein 1 (LMP1) is one of the few EBV products expressed in PEL cells. Results showed that LMP1 was sufficient to induce uch-l1 expression, and co-expression of LMP1 and LANA had an additive effect on uch-l1 expression. These results indicate that viral latency products of both human γ-herpesviruses contribute to uch-l1 expression, which may contribute to the progression of lymphoid malignancies