Spectral Functions in Holographic Renormalization Group Flows

The spectrum of two-point functions in a holographic renormalization group flow from an ultraviolet (UV) to an infrared (IR) conformal fixed point is necessarily continuous. For a toy model, the spectral function does not only show the expected UV and IR behaviours, but other interesting features such as sharp peaks and oscillations in the UV. The spectral functions for the SU(3)xU(1) flow in AdS_4/CFT_3 and the SU(2)xU(1) flow in AdS_5/CFT_4 are calculated numerically. They exhibit a simple cross-over behaviour and reproduce the conformal dimensions of the dual operators in the UV and IR conformal phases.Comment: 20 pages, 6 figures v2: added referene

Glueball condensates as holographic duals of supersymmetric Q-balls and boson stars

We study non-spinning Q-balls and boson stars in 4-dimensional Anti-de Sitter (AdS) space-time. We use an exponential scalar field potential that appears in gauge-mediated supersymmetry (SUSY) breaking in the minimal supersymmetric extension of the Standard Model (MSSM). We investigate the dependence of the charge and mass of these non-topological solitons on the negative cosmological constant, the frequency that appears in the periodic time-dependence as well as on the ratio between the SUSY breaking scale and the Planck mass. Next to fundamental solutions without nodes in the scalar field function we also construct radially excited solutions. In the second part of the paper we put the emphasis on the holographic interpretation of these solutions in terms of Bose-Einstein condensates of scalar glueballs that are described by a strongly coupled Quantum Field Theory (QFT) on the boundary of global AdS.Comment: 17 pages including 11 figures; v2: 19 pages including 13 figures, references added, figures adde

MiRNA deregulation targets specific pathways in leiomyosarcoma development: An in silico analysis

BackgroundMicroRNA (miRNA) mediate post-transcriptional gene repression and are involved in a variety of human diseases, including cancer. Soft tissue sarcomas are rare malignancies with a variety of histological subtypes which may occur virtually anywhere in the human body. Leiomyosarcoma is one of the most common subtypes, shows a smooth muscle phenotype and its cancerogenesis is still unclear. The aim of our study was to investigate the potential role of miRNA differential expression in leiomyosarcoma development.MethodsWe first employed the Sarcoma microRNA Expression Database, a repository that describes the patterns of over 1000 miRNA expression in various human sarcoma types, to identify differentially expressed miRNA comparing leiomyosarcoma and smooth muscle samples. Subsequently, we identified putative target genes of those miRNAs with the TargetScan prediction tool. Finally, we evaluated whether the retrieved pool of putative targets was enriched in genes belonging to specific molecular pathways by means of the Enrichr analysis tool. Protein-protein network analysis was analyzed by means of the STRING web tool.ResultsOut of 1120 miRNAs tested, the expression of 301 miRNAs was statistically significantly different between leiomyosarcoma and smooth muscle samples. The hypothetical targets could be predicted for 172 miRNAs. 438 genes were predicted to be the targets with high confidence (cumulative weighted context score cut-off level less than -1.0) and analyzed for belonging to specific molecular pathways. Pathway analysis suggested that RNA Polymerase III, tRNA functions and synaptic neurotransmission (with special regard to dopamine mediated signaling) could be involved in leiomyosarcoma development.ConclusionsOur results demonstrate that data mining of publicly available repositories can be useful to suggest molecular pathways underlying the pathogenesis of rare tumors such as leiomyosarcoma

A Test of the AdS/CFT Correspondence Using High-Spin Operators

In two remarkable recent papers, hep-th/0610248 and hep-th/0610251, the complete planar perturbative expansion was proposed for the universal function of the coupling, f(g), appearing in the dimensions of high-spin operators of the N=4 SYM theory. We study numerically the integral equation derived in hep-th/0610251, which implements a resummation of the perturbative expansion, and find a smooth function that approaches the asymptotic form predicted by string theory. In fact, the two leading terms at strong coupling match with high accuracy the results obtained for the semiclassical folded string spinning in $AdS_5$. This constitutes a remarkable confirmation of the AdS/CFT correspondence for high-spin operators, and equivalently for the cusp anomaly of a Wilson loop. We also make a numerical prediction for the third term in the strong coupling series.Comment: 11 pages, 1 figure; added references, corrected typo

The Gauge Dual of Gauged N=8 Supergravity Theory

The most general SU(3)-singlet space of gauged N=8 supergravity in four-dimensions is studied recently. The SU(3)-invariant six scalar fields are realized by six real four-forms. A family of holographic N=1 supersymmetric RG flows on M2-branes in three-dimensions is described. This family of flows is driven by three independent mass parameters from the N=8 SO(8) theory and is controlled by two IR fixed points, N=1 G_2-invariant one and N=2 SU(3) x U(1)-invariant one. The generic flow with arbitrary mass parameters is N=1 supersymmetric and reaches to the N=2 SU(3) x U(1) fixed point where the three masses become identical. A particular N=1 supersymmetric SU(3)-preserving RG flow from the N=1 G_2-invariant fixed point to the N=2 SU(3) x U(1)-invariant fixed point is also discussed.Comment: 19pp; added the footnote 1, improved the conclusion and to appear in IJMP

What Will LADEE Tell Us About the Lunar Atmosphere?

The only species that have been confirmed in the lunar exosphere are Na, K, Ar, and He. However, models for the production and loss of lunar regolith-derived exospheric species from source processes including micrometeoroid impact vaporization, sputtering, and, for Na and K, photon-stimulated desorption, predict a host of other species should exist in the lunar exosphere. Assuming that loss processes are limited to ballistic escape, photoionization, and recycling to the surface, we have computed column abundances and compared them to published upper limits from the Moon and to detected abundances from Mercury. Our results suggest that available measurements often do not constrain models, and underline the need for improved spectroscopic measurements of the lunar exosphere. Such investigations are planned by the Lunar Atmosphere and Dust Environment Explorer (LADEE) spacecraft. Our calculations indicate that LADEE measurements promise to make definitive observations or set stringent upper limits for all regolith-driven exospheric species because of their favorable signal to noise ratio. Our models, along with LADEE observations, will constrain assumed model parameters for the Moon, such as sticking coefficients, source processes, and velocity distributions

First Evidence of Persistent Nighttime Temperature Structures in the Neutral Thermosphere of Mars

Using two Mars years of data collected by the Neutral Gas and Ion Mass Spectrometer on the Mars Atmosphere and Volatiles EvolutioN spacecraft, we reconstruct the local solar time structure of the Martian equatorial thermosphere for the dawn and dusk sectors. The results indicate the presence of several persistent features near the dusk and dawn terminators appearing in the neutral temperature and in the O, Ar, N2, and CO2 densities. The dusk temperature features include a minimum at the terminator surrounded by two local maxima with amplitudes between 20 and 40 K. A nighttime temperature enhancement occurs at a local solar time of 4–5 hr and has an amplitude between 50 and 100 K relative to the surrounding temperatures. The observed enhancements are interpreted to be a result of either nighttime dynamical heating caused by converging and downwelling winds or of a terminator wave originating in the lower atmosphere.Plain Language SummaryNASA’s Mars Atmosphere and Volatiles EvolutioN (MAVEN) spacecraft has been collecting information about the Mars’ upper atmosphere since November 2014. In our study we examined the temperature in the upper atmosphere measured by a gas analyzer on MAVEN that periodically sniffs the air around it. By combining several years of data, we reconstructed a map of atmospheric temperatures dividing it into equatorial daytime, morning, evening, and nighttime regions. The results indicate that local patches of warm atmosphere extend about 300–600 km along the Martian equator (3–6 hr driving distance at highway speeds) on the nightside near morning and evening. One possible reason for these nighttime warm spots is the air currents in the Martian upper atmosphere. As the sun heats the dayside atmosphere, it expands and causes wind currents to blow away from the dayside region. These wind currents can extend away from the equator then return on the nightside colliding in the morning and evening regions. The resulting meeting of wind currents can heat the upper atmosphere. Warmer air escapes from the upper atmosphere faster. Because of this, these nighttime patches of warm air could have contributed to a faster escape of Martian atmospheric gases than previously believed.Key PointsPersistent neutral density and temperature enhancements are observed within 30 min of the dusk terminatorA persistent neutral density enhancement is also observed prior to the dawn terminator at around 4–5 local timeThe neutral density features are observed in all species and appear to be associated with enhancements in neutral temperaturePeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146482/1/grl57932.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146482/2/grl57932_am.pd

Metallic ions in the upper atmosphere of Mars from the passage of comet C/2013 A1 (Siding Spring)

We report the first in situ detection of metal ions in the upper atmosphere of Mars resulting from the ablation of dust particles from comet Siding Spring. This detection was carried out by the Neutral Gas and Ion Mass Spectrometer on board the Mars Atmosphere and Volatile Evolution Mission. Metal ions of Na, Mg, Al, K, Ti, Cr, Mn, Fe, Co, Ni, Cu, and Zn, and possibly of Si, and Ca, were identified in the ion spectra collected at altitudes of ~185 km. The measurements revealed that Na+ was the most abundant species, and that the remaining metals were depleted with respect to the CI (type 1 carbonaceous Chondrites) abundance of Na+. The temporal profile and abundance ratios of these metal ions suggest that the combined effects of dust composition, partial ablation, differential upward transport, and differences in the rates of formation and removal of these metal ions are responsible for the observed depletion

On the Strong Coupling Scaling Dimension of High Spin Operators

We give an exact analytic solution of the strong coupling limit of the integral equation which was recently proposed to describe the universal scaling function of high spin operators in N = 4 gauge theory. The solution agrees with the prediction from string theory, confirms the earlier numerical analysis and provides a basis for developing a systematic perturbation theory around strong coupling.Comment: 26 pages, 2 figure