A Wind-powered Rover for a Low-Cost Venus Mission

Venus, with a surface temperature of 450 C and an atmospheric pressure 90 times higher than that of the Earth, is a difficult target for exploration. However, high-temperature electronics and power systems now being developed make it possible that future missions may be able to operate in the Venus environment. Powering such a rover within the scope of a Discovery class mission will be difficult, but harnessing Venus' surface winds provides a possible way to keep a powered rover small and light. This project scopes out the feasibility of a wind-powered rover for Venus surface missions. Two rover concepts, a land-sailing rover and a wind-turbine-powered rover, were considered. The turbine-powered rover design is selected as being a low-risk and low-cost strategy. Turbine detailed analysis and design shows that the turbine can meet mission requirements across the desired range of wind speeds by utilizing three constant voltage generators at fixed gear ratios

SCIPP: An Expanded Community of Practice - Community Publishing

SCIPP redefines and expands the existing notions about what makes for a vibrant and robust community of practice by partnering CSUSB students and professors with K-12 students, parents, and educators, along with committed community partners. SCIPP encourages curiosity in ways that leads to critical thinking, exploration, risk taking , confidence building, open-mindedness, and other personal traits that equip them with the softskills to be active, critical, and creative contributors to our communities. SCIPP pedagogy embraces our students\u27 collective wisdom and focuses on relational building where multi-directional communication is promoted and students are viewed as equal stakeholders in their own educations. SCIPP puts collaboration into action which in turn fosters community-based lifelong learning. SCIPP provides the open intellectual space for future university students (our K-12 students) to engage with existing university students in meaningful ways so as to sustain interconnected partnerships facilitating community engagement. It supports parents as experts in the education of their children and acknowledges parents as the first conduits to spark their children’s imagination while they actively participate in education enriching activities and programs. Everyone involved is committed to creating a secure and open atmosphere for dreaming, sharing, and learning. Together we explore the aspects of community publishing through collaborative learning in formal and informal settings relating to digital and printed medias

Cranston.pmd

Abstract. A new orthocladiine midge, Hydrobaenus saetheri Cranston, new species, is described from larvae, pupae and adults, evidently belonging to the genus Hydrobaenus Fries. Larvae aestivate over summer, and commence development as soon as wetted when winter-rains induce flow in seasonal waterways. Larvae of this species dominate in the early flow, and adult numbers can reach nuisance levels in mid-winter

El proceso asociativo como ventaja competitiva en las microempresas, caso Quevedo-Ecuador

One of the main actors in local development is the MSMEs (micro, small and medium enterprises). However, many have difficulties to stay in the market, so it is necessary to search alternatives such as associativity, to increase efficiency and competitiveness. The present research was carried out through a descriptive study. It tries to analyze if within the local productive system, the microenterprises participate of associative processes in Quevedo, since, they constitute the 96% of the business fabric. For that, 359 microentrepreneurs were surveyed, as well as the main problems that microenterprises in Quevedo are experiencing. There is a clear reality that microenterprises have little participation in associative processes, and the few that are associated, do so with the purpose of improving the marketing of their products. The government's lack of support to improve the competitiveness of micro-enterprises in Quevedo is evident.Uno de los principales actores del desarrollo local son las Mipymes (micro, pequeñas y medianas empresas), sin embargo muchas tienen dificultades para mantenerse en el mercado, por eso es necesario buscar alternativas como la asociatividad, para incrementar su eficiencia y competitividad. El presente trabajo de investigación se realizó mediante un estudio descriptivo. Procura analizar si dentro del sistema productivo local, las microempresas participan de procesos asociativos en Quevedo, ya que, constituyen el 96% del tejido empresarial. Para eso se encuestó a 359 microempresarios, adicionalmente se conocerán los principales problemas por las que están atravesando las microempresas en Quevedo. Existe una clara realidad que las microempresas tienen escasa participación en procesos asociativos, y los pocos que se asocian, lo hacen con el propósito de mejorar la comercialización de sus productos. Es evidente el poco apoyo del gobierno para mejorar la competitividad de las microempresas en Quevedo

Individual-level and Population-level Historical Prey Demand of San Francisco Estuary Striped Bass Using a Bioenergetics Model

Striped bass are both a major predator of native fishes and support a recreational fishery in the San Francisco Estuary (the estuary). Quantifying their demands on their prey is important for understanding long-term trends of fish in the estuary. In this study, we: (i) applied a bioenergetics model of sub-adult (age 1 and age 2) and adult (age 3+) striped bass (Morone saxatilis) to quantify long-term consumption patterns from 1969 through 2004 in the estuary; (ii) developed a method to estimate the abundances of sub-adult striped bass; (iii) evaluated how consumption varied by age and gender; and (iv) identified factors that affect the resulting consumption estimates. On a ‘per capita’ basis, modeled individual prey fish consumption increased after 1990, and individual total and prey fish consumption by age-2 striped bass increased after 1994. Conversely, individual total and prey fish consumption by adult striped bass decreased over the period analyzed. This decline in individual consumption over the study period was related to a decline in mean length at age of adults. As expected, long-term trends in population consumption (total and prey fish) by all ages of striped bass (ages 1 through 6) closely followed their respective population- abundance trends. Population total consumption and prey fish-specific consumption by sub-adult striped bass was found to be similar to the population consumption by adult striped bass, largely because of the high abundance of sub-adults. Unlike adult striped bass that may emigrate and forage in the Pacific Ocean, the majority of sub-adult striped bass reside within the estuary; hence, consumption by the relatively abundant sub-adult population may have significant effects upon their estuarine prey species

Individual-level and Population-level Historical Prey Demand of San Francisco Estuary Striped Bass Using a Bioenergetics Model

Striped bass are both a major predator of native fishes and support a recreational fishery in the San Francisco Estuary (the estuary). Quantifying their demands on their prey is important for understanding long-term trends of fish in the estuary. In this study, we: (i) applied a bioenergetics model of sub-adult (age 1 and age 2) and adult (age 3+) striped bass (Morone saxatilis) to quantify long-term consumption patterns from 1969 through 2004 in the estuary; (ii) developed a method to estimate the abundances of sub-adult striped bass; (iii) evaluated how consumption varied by age and gender; and (iv) identified factors that affect the resulting consumption estimates. On a ‘per capita’ basis, modeled individual prey fish consumption increased after 1990, and individual total and prey fish consumption by age-2 striped bass increased after 1994. Conversely, individual total and prey fish consumption by adult striped bass decreased over the period analyzed. This decline in individual consumption over the study period was related to a decline in mean length at age of adults. As expected, long-term trends in population consumption (total and prey fish) by all ages of striped bass (ages 1 through 6) closely followed their respective population- abundance trends. Population total consumption and prey fish-specific consumption by sub-adult striped bass was found to be similar to the population consumption by adult striped bass, largely because of the high abundance of sub-adults. Unlike adult striped bass that may emigrate and forage in the Pacific Ocean, the majority of sub-adult striped bass reside within the estuary; hence, consumption by the relatively abundant sub-adult population may have significant effects upon their estuarine prey species

Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials.

Screening of the GSK corporate collection, some 1.9 million compounds, against Plasmodium falciparum (Pf), revealed almost 14000 active hits that are now known as the Tres Cantos Antimalarial Set (TCAMS). Followup work by Calderon et al. clustered and computationally filtered the TCAMS through a variety of criteria and reported 47 series containing a total of 522 compounds. From this enhanced set, we identified the carbamoyl triazole TCMDC-134379 (1), a known serine protease inhibitor, as an excellent starting point for SAR profiling. Lead optimization of 1 led to several molecules with improved antimalarial potency, metabolic stabilities in mouse and human liver microsomes, along with acceptable cytotoxicity profiles. Analogue 44 displayed potent in vitro activity (IC50 = 10 nM) and oral activity in a SCID mouse model of Pf infection with an ED50 of 100 and ED90 of between 100 and 150 mg kg(-1), respectively. The results presented encourage further investigations to identify the target of these highly active compounds

Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials

Screening of the GSK corporate collection, some 1.9 million compounds, against Plasmodium falciparum (<i>Pf</i>), revealed almost 14000 active hits that are now known as the Tres Cantos Antimalarial Set (TCAMS). Followup work by Calderon et al. clustered and computationally filtered the TCAMS through a variety of criteria and reported 47 series containing a total of 522 compounds. From this enhanced set, we identified the carbamoyl triazole TCMDC-134379 (<b>1</b>), a known serine protease inhibitor, as an excellent starting point for SAR profiling. Lead optimization of <b>1</b> led to several molecules with improved antimalarial potency, metabolic stabilities in mouse and human liver microsomes, along with acceptable cytotoxicity profiles. Analogue <b>44</b> displayed potent in vitro activity (IC₅₀ = 10 nM) and oral activity in a SCID mouse model of <i>Pf</i> infection with an ED₅₀ of 100 and ED₉₀ of between 100 and 150 mg kg⁻¹, respectively. The results presented encourage further investigations to identify the target of these highly active compounds

Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials

Screening of the GSK corporate collection, some 1.9 million compounds, against Plasmodium falciparum (<i>Pf</i>), revealed almost 14000 active hits that are now known as the Tres Cantos Antimalarial Set (TCAMS). Followup work by Calderon et al. clustered and computationally filtered the TCAMS through a variety of criteria and reported 47 series containing a total of 522 compounds. From this enhanced set, we identified the carbamoyl triazole TCMDC-134379 (<b>1</b>), a known serine protease inhibitor, as an excellent starting point for SAR profiling. Lead optimization of <b>1</b> led to several molecules with improved antimalarial potency, metabolic stabilities in mouse and human liver microsomes, along with acceptable cytotoxicity profiles. Analogue <b>44</b> displayed potent in vitro activity (IC₅₀ = 10 nM) and oral activity in a SCID mouse model of <i>Pf</i> infection with an ED₅₀ of 100 and ED₉₀ of between 100 and 150 mg kg⁻¹, respectively. The results presented encourage further investigations to identify the target of these highly active compounds