Temporal Cross-Media Retrieval with Soft-Smoothing

Multimedia information have strong temporal correlations that shape the way modalities co-occur over time. In this paper we study the dynamic nature of multimedia and social-media information, where the temporal dimension emerges as a strong source of evidence for learning the temporal correlations across visual and textual modalities. So far, cross-media retrieval models, explored the correlations between different modalities (e.g. text and image) to learn a common subspace, in which semantically similar instances lie in the same neighbourhood. Building on such knowledge, we propose a novel temporal cross-media neural architecture, that departs from standard cross-media methods, by explicitly accounting for the temporal dimension through temporal subspace learning. The model is softly-constrained with temporal and inter-modality constraints that guide the new subspace learning task by favouring temporal correlations between semantically similar and temporally close instances. Experiments on three distinct datasets show that accounting for time turns out to be important for cross-media retrieval. Namely, the proposed method outperforms a set of baselines on the task of temporal cross-media retrieval, demonstrating its effectiveness for performing temporal subspace learning.Comment: To appear in ACM MM 201

Small Radial Compressors: Aerodynamic Design And Analysis

This paper presents a computational procedure for the analysis of steady one-dimensional centrifugal compressor. The numerical model is based on the conservation principles of mass, momentum and energy, and has been utilized to predict the operational and aerodynamic characteristics of a small centrifugal compressor as well as determining the performance and geometry of compressor blades, both straight and curved. © 1998 OPA (Overseas Publishers Association) N.V. Published by license under the Gordon and Breach Science Publishers imprint.43189200Bammert, K., Rautenberg, M., Wittekindt, W., Matching of turbo-components described by the example of impeller and diffuser in a centrifugal compressor, Part I: Aerothermodynamic coupling of impeller and diffuser, Part II: Optimised stage efficiency of a centrifugal compressor (1979) Transactions of the ASME, Journal of Engineering for Power, pp. 59-65. , Paper No. 79-GT/Isr-9Benevenuto, F.J., (1996) Estudoparamétrico de Uma Mini Turbina a Gás do Tipo Radial, , São Carlos, SP, Brasil. 182 p. M.Sc. Thesis, Escola de Engenharia de São Carlos, Universidade de São PauloCame, P.M., The development, application and experimental evaluation of a design procedure for centrifugal compressors (1978) Proceedings of the Institution of Mechanical Engineers, 192 (5), pp. 49-67Clements, W.W., Artt, D.W., The influence of diffuser channel geometry on the flow range and efficiency of a centrifugal compressor (1987) Proceedings of the Institution of Mechanical Engineers, Part A, 201 (A2), pp. 145-152Cohen, H., Rogers, G.F.C., Saravanamutoo, H.I.H., (1987) Gas Turbine Theory, 3rd Ed., p. 114. , Longman Scientific & Technical, EnglandKenny, D.P., The history and future of the centrifugal compressor in aviation gas turbines (1984) Society of Automotive Engineers, , Oct. SAE Paper 841635, 15 pRosolen, C.V.A.G., (1994) Desenvolvimento Analítico e Numérico de um Compressor Centrífugo Subsônico de Baixa Potência, , São Carlos, SP, Brasil. 148 p. M.Sc. Thesis, Escola de Engenharia de São Carlos, Universidade de São PauloSenoo, Y., Pressure losses and flow field distortion induced by tip clearance of centrifugal an axial compressors (1987) JSME International Journal, 30 (261), pp. 375-385Stow, P., The development of advanced computational methods for turbomachinery blade design (1989) International Journal for Numerical Methods in Fluids, 9 (8), pp. 921-941Takeda, A.S., (1987) A Centrifugal Compressor Design Assessment for a Small Gas Turbine, , Cranfield. 161 p. M.Sc. Thesis, School of Mechanical Engineering, Cranfield Institute of Technolog

Efficacy of radiofrequency ablation in autonomous functioning thyroid nodules. A systematic review and meta-analysis

Whether thermal ablation is effective to treat toxic thyroid nodules (TTN) is still unknown. Aim of this review was to achieve more robust evidence on the efficacy of radiofrequency ablation (RFA) in treating TTN in terms of TSH normalization, thyroid scintiscan, and volume reduction rate (VRR). A comprehensive literature search of PubMed/Medline and Scopus was performed in November 2018 to retrieve published studies. Original papers reporting TTN treated by RFA and later followed-up were eligible. Excluded were: articles not within this field, articles with unclear data, overlapping series, case/series reports. Discordances were solved in a final collegial meeting. Information was collected concerning population features, treatment procedure, follow-up, cases with TSH normalization, cases with scintiscan normalization, VRR of nodules. Pooled prevalence of patients with TSH or scintiscan normalization, and pooled VRR over time were calculated. For statistical analysis, the random-effects model was used. Eight articles published between 2008 and 2018 were included. The overall number of AFTN treated by RFA was 205. Five studies used a single session of treatment. The time of follow-up ranged from six to 24 months. The pooled rate of patients with TSH normalization was 57%. The pooled rate of patients with scintigraphically proven optimal response was 60%. The pooled VRR at 1 year was 79%. Baseline nodules volume was associated with the rate of TSH normalization. In conclusion, a moderate efficacy of RFA in treating TTN was found, and this can represent a solid starting point in this field

Using visual scores for genomic prediction of complex traits in breeding programs.

An approach for handling visual scores with potential errors and subjectivity in scores was evaluated in simulated and blueberry recurrent selection breeding schemes to assist breeders in their decision-making. Most genomic prediction methods are based on assumptions of normality due to their simplicity and ease of implementation. However, in plant and animal breeding, continuous traits are often visually scored as categorical traits and analyzed as a Gaussian variable, thus violating the normality assumption, which could affect the prediction of breeding values and the estimation of genetic parameters. In this study, we examined the main challenges of visual scores for genomic prediction and genetic parameter estimation using mixed models, Bayesian, and machine learning methods. We evaluated these approaches using simulated and real breeding data sets. Our contribution in this study is a five-fold demonstration: (i) collecting data using an intermediate number of categories (1-3 and 1-5) is the best strategy, even considering errors associated with visual scores; (ii) Linear Mixed Models and Bayesian Linear Regression are robust to the normality violation, but marginal gains can be achieved when using Bayesian Ordinal Regression Models (BORM) and Random Forest Classification; (iii) genetic parameters are better estimated using BORM; (iv) our conclusions using simulated data are also applicable to real data in autotetraploid blueberry; and (v) a comparison of continuous and categorical phenotypes found that investing in the evaluation of 600-1000 categorical data points with low error, when it is not feasible to collect continuous phenotypes, is a strategy for improving predictive abilities. Our findings suggest the best approaches for effectively using visual scores traits to explore genetic information in breeding programs and highlight the importance of investing in the training of evaluator teams and in high-quality phenotyping

Malignant perivascular epithelioid cell tumor of the uterus

Perivascular epithelioid cell tumors (PEComas) are a rare collection of tumors arising in a wide array of anatomic locations and characterized by a myomelanocytic phenotype. PEComas which occur in non-classic anatomic distributions are known as perivascular epithelioid cell tumor-not otherwise specified (PEComa-NOS), and one of the most common primary sites for PEComa-NOS is the uterus. The risk of aggressive behavior of these tumors has been linked to a number of factors evaluable on pathologic review following initial surgical resection. We report a case of PEComa-NOS of the uterus with multiple high-risk features, including frank vascular invasion, with no evidence of recurrent disease 18 months following initial surgical resection

Immunoexpression of HOXB7 and HOXB9 in salivary gland tumours

BACKGROUND : Salivary gland carcinomas are uncommon neoplasms and the identification of new prognostic indicators could improve their management. HOXB7 and HOXB9 are members of the class I homeobox-containing genes important for normal embryogenesis and that are dysregulated in several human neoplasms. This study investigated HOXB7 and HOXB9 expression in salivary gland tumourigenesis, they correlation with neoplastic proliferative and angiogenic features, and their importance as prognostic markers. METHODS : A hundred and fifty salivary gland tumours were organized in tissue microarray and expression of CD105, Ki67, HOXB7 and HOXB9 were determined through immunohistochemistry. Reactions were quantified and correlated with clinicopathological parameters. RESULTS : In normal glands HOXB7 was found in basal cells, whereas HOXB9 was seen in serous acinar and scattered ductal cells. Malignancies exhibited an increased vascular density, proliferative index, HOXB7 and HOXB9 expression when compared with pleomorphic adenoma and Warthin tumour. Significant correlation was found between HOXB7 and CD105 (p = 0.004) in adenoid cystic carcinomas, and HOXB7 higher expression significantly correlated with the presence of paresthesia (p = 0.02). No marker exhibited a significant association with survival rates (p > 0.05). CONCLUSION : HOXB7 and HOXB9 were expressed in normal salivary gland and were present in benign and malignant tumours derived from these structures, and HOXB7 significantly correlated with neoangiogenesis in AdCC. These findings suggest that both proteins might play a role in salivary gland tumourigenesis, but they were not significant prognostic determinants in this sample.Grants from the São Paulo State Research Foundation (Brazil), processes numbers 2009/53839-2, 2012/07519-9 and 2012/10781-7, and from the Brazilian Coordination of Higher Education (CAPES/PDSE 2892/13-8).http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1600-07142017-10-31hb2016Oral Pathology and Oral Biolog