From professional knowledge – to transprofessional competence

The description of the main changes to the paradigm of vocational education happened when its essence transfers from supporting to innovative type is presented in the article. When developing competence-based models and methods of assessment of training results of future experts is offered to consider features of working conditions, namely to determine the level of not programmability of a production activityРассматриваются основные парадигмальные изменения, происходящие в профессиональном образовании при его переходе от поддерживающего к инновационному. Предлагается при разработке компетентностных моделей и методов оценки результатов обучения будущих специалистов учитывать особенности предполагаемых производственных условий, а именно определять уровень непрограммируемости производственной деятельност

ABOUT METHODS OF SEISMIC ANALYSIS OF UNDERGROUND STRUCTURES

As is known, underground facilities are an integral part of the infrastructure of modern society. These objects have some specific characteristics such as complex construction, high cost, long life cycle, etc. Once it is destroyed, the direct and indirect losses are more seriousness than the general structure in the ground. Under-ground facilities built in areas subject to earthquake activity must withstand both seismic and static loading. Therefore, it is very important to carry on the seismic design of the underground structure in a safe and economi-cal way. The distinctive paper presents a summary of the current state of seismic analysis for underground struc-tures. Classification and brief overview of methods of seismic analysis of underground structures (force-based methods, displacement-based methods, numerical methods of seismic analysis of coupled system “soil – under-ground structure”) are presented, problems of soil-structure interaction are under consideration as well. So-called static finite element method with substructure technique for seismic analysis of underground structures is de-scribed

Measurement of tensor analyzing powers in deuteron photodisintegration

New accurate measurement of tensor analyzing powers T20, T21 and T22 in deuteron photodisintegration has been performed. Wide-aperture non-magnetic detectors allowed to cover broad kinematic ranges in a single setup: photon energy = 25 to 600 MeV, proton emission angle in CM = 24 to 48 deg. and 70 to 102 deg. New data provide a significant improvement of a few existing measurements. The angular dependency of the tensor asymmetries in deuteron photodisintegration is extracted for the first time.Comment: 4 pages, 5 figures, submitted to Phys. Rev. Let

ABOUT SEVERAL NUMERICAL AND SEMIANALYTICAL METHODS OF LOCAL STRUCTURAL ANALYSIS

Numerical or semianalytical solution of problems of structural mechanics with immense number of unknowns is time-consuming process. High-accuracy solution at all points of the model is not required normally, it is necessary to find only the most accurate solution in some pre-known domains. The choice of these domains is a priori data with respect to the structure being modelled. Designers usually choose domains with the so-called edge effect (with the risk of significant stresses that could lead to destruction of structures) and regions which are subject to specific operational requirements. Stress-strain state in such domains is important. Wavelets provide effective and popular tool for local structural analysis. Operational and variational formulations of problems of structural mechanics with the use of method of extended domain are presented. After discretization and obtaining of governing equations, problems are transformed to a multilevel space by multilevel wavelet transform. Discrete wavelet basis is used and corresponding direct and inverse algorithms of transformations are performed. Due to special algorithms of averaging, reduction of the problems is provided. Wavelet-based methods allows reducing the size of the problems and obtaining accurate results in selected domains simultaneously. These are rather efficient methods for evaluation of local phenomenon in structures

Radio-frequency discharges in Oxygen. Part 1: Modeling

In this series of three papers we present results from a combined experimental and theoretical effort to quantitatively describe capacitively coupled radio-frequency discharges in oxygen. The particle-in-cell Monte-Carlo model on which the theoretical description is based will be described in the present paper. It treats space charge fields and transport processes on an equal footing with the most important plasma-chemical reactions. For given external voltage and pressure, the model determines the electric potential within the discharge and the distribution functions for electrons, negatively charged atomic oxygen, and positively charged molecular oxygen. Previously used scattering and reaction cross section data are critically assessed and in some cases modified. To validate our model, we compare the densities in the bulk of the discharge with experimental data and find good agreement, indicating that essential aspects of an oxygen discharge are captured.Comment: 11 pages, 10 figure

Nuclear Polarization of Molecular Hydrogen Recombined on a Non-metallic Surface

The nuclear polarization of $\mathrm{H}_2$ molecules formed by recombination of nuclear polarized H atoms on the surface of a storage cell initially coated with a silicon-based polymer has been measured by using the longitudinal double-spin asymmetry in deep-inelastic positron-proton scattering. The molecules are found to have a substantial nuclear polarization, which is evidence that initially polarized atoms retain their nuclear polarization when absorbed on this type of surfac

Measurement of Angular Distributions and R= sigma_L/sigma_T in Diffractive Electroproduction of rho^0 Mesons

Production and decay angular distributions were extracted from measurements of exclusive electroproduction of the rho^0(770) meson over a range in the virtual photon negative four-momentum squared 0.5< Q^2 <4 GeV^2 and the photon-nucleon invariant mass range 3.8< W <6.5 GeV. The experiment was performed with the HERMES spectrometer, using a longitudinally polarized positron beam and a ^3He gas target internal to the HERA e^{+-} storage ring. The event sample combines rho^0 mesons produced incoherently off individual nucleons and coherently off the nucleus as a whole. The distributions in one production angle and two angles describing the rho^0 -> pi+ pi- decay yielded measurements of eight elements of the spin-density matrix, including one that had not been measured before. The results are consistent with the dominance of helicity-conserving amplitudes and natural parity exchange. The improved precision achieved at 47 GeV, reveals evidence for an energy dependence in the ratio R of the longitudinal to transverse cross sections at constant Q^2.Comment: 15 pages, 15 embedded figures, LaTeX for SVJour(epj) document class Revision: Fig. 15 corrected, recent data added to Figs. 10,12,14,15; minor changes to tex

Analysis of Mechanical Safety of Stadiums for the World Cup 2018

It is obvious that contemporary design and construction of unique buildings and structures is unthinkable without mathematical (numerical) and computer modelling and advanced analysis ofload-bearing structures under various kinds ofloads and impacts. One of the most ambitious and important construction projects is the uniquelarge-span structures. These are, in particular, stadiums, sports palaces and water parks, shopping malls, pedestrian, road and railway bridges of various design solutions. The distinctive paper is devoted to theoretical foundations and results of mathematical (numerical) modeling of the state (in terms of the analysis of stress-strain state, strength and stability) of football stadiums built for the 2018 FIFA World Cup in Russia. Finite element method is used for approximation and high-precision numerical solution of corresponding boundary problems of structural mechanics. It is the most universal and powerful numerical method of mechanics. The paper, in particular, describes some features of development of finite element models and the main results of the analysis of the mechanical (structural) safety of three- dimensionallarge-span systems "soil foundation - reinforced concrete structures of foundations and stands - steel structures of the coating and facades" of these football stadiums with the basic and specialload combinations. In addition, the key procedures of scientific support during the corresponding expertise and assessments are outlined. Generally, socially significant and knowledge-intensive problem of providing mechanical (constructive) safety of unique combined objects of construction (three-dimensional systems "foundation - reinforced concrete structures of foundations and stands - steel structures of coating and facades") has been solved at a new level as a result of the performed complex of research works

Лекарственный анафилактический шок

Among the major etiological factors that can cause an anaphylactic shock (AS), drugs account for 31.2-46.5%.Purpose of the work was to identify factors associated with a high AS risk based on 2010-2018 records made in the Republic of Crimea.Materials and methods. The objects of the study were 112 information reports about adverse reactions (AR) to medicine remedies (MR), which were recorded in the regional database of spontaneous information reports—ARCAD — in the Republic of Crimea during 2010-2018. A retrospective analysis of drug-induced AS cases has been carried out for the following indicators: intake and route of administration of drugs, gender, age, history of allergies.Results of the study have shown that antimicrobial drugs, local anesthetics, analgesics-antipyretics, X-ray contrast iodine-containing substances, and non-steroidal anti-inflammatory drugs featured the highest AS incidence. Most frequently, AS cases were observed in patients aged 31 to 60 years, with no significant differences between men (57 cases) and women (54 cases). In one case the patient's gender was missed or not stated.The leader in AS incidence is Ceftriaxone, which application was associated with 22 cases of such AR. In 87 cases, AS was found associated with parenteral administration drugs, the intravenous route of administration being predominant (44 cases). In 97 cases, development of drug-induced AS was life-threatening and required emergency pharmacotherapy; 8 reports contained a lethal outcome record.Conclusions. Attention should be paid to high incidence, severity, and instant progression rate of adverse reactions in the form of AS. Considering the AS progression rate and facts of ignored past history of drugs and allergies, as well as pharmacological correction errors, additional educational events are worth conducting for physicians specializing in different fields.Среди основных этиологических факторов, способных вызвать развитие анафилактического шока (АШ) у пациентов, лекарственные препараты составляют 31,2-46,5%.Цель работы — выявление факторов, ассоциированных с повышенным риском развития АШ, зарегистрированного в 2010-2018 гг. у пациентов в Республике Крым.Материалы и методы. Объектами исследования стали 112 карт-извещений о нежелательных реакциях (НР) лекарственных средств (ЛС), зарегистрированных в региональной базе спонтанных сообщений ARCADe в Республике Крым за период 2010-2018 гг. На основании карт-извещений провели ретроспективный анализ случаев возникновения лекарственного АШ по следующим показателям: прием и способ введения препаратов, пол, возраст, аллергологический анамнез.Результаты исследования показали, что лидерами по частоте развития АШ являлись противомикробные препараты местные анестетики, анальгетики-антипиретики, рентгеноконтрастные йодсодержащие вещества и нестероидные противовоспалительные препараты. Случаи развития АШ чаще всего наблюдали у пациентов в возрасте от 31 до 60 лет, у мужчин с большей частотой (57 случаев), чем у женщин (54 случая). В одном случае указания на пол пациента отсутствовали. Лидером по частоте развития случаев АШ являлся цефтриаксон, с применением которого было ассоциировано 22 случая таких НР Выявили, что в 87 случаях АШ развивался на фоне парентерального введения препаратов, среди которых преобладал внутривенный путь введения (44 случая). Развитие лекарственного АШ в 97 случаях представляло собой угрозу жизни пациента и требовало неотложной фармакотерапии, в 8 картах-извещениях содержалась информация о летальном исходе для пациентов.Выводы. Стоит обратить внимание на высокую частоту, серьезность и мгновенную скорость развития нежелательных реакций в виде АШ. Учитывая скорость развития АШ и факты игнорирования лекарственного и аллергологического анамнеза, ошибки медикаментозной коррекции следует рассмотреть возможность проведения дополнительных образовательных мероприятий для врачей разных специальностей

Transcriptome analysis of haploid male gametophyte development in Arabidopsis

BACKGROUND: The haploid male gametophyte generation of flowering plants consists of two- or three-celled pollen grains. This functional specialization is thought to be a key factor in the evolutionary success of flowering plants. Moreover, pollen ontogeny is also an attractive model in which to dissect cellular networks that control cell growth, asymmetric cell division and cellular differentiation. Our objective, and an essential step towards the detailed understanding of these processes, was to comprehensively define the male haploid transcriptome throughout development. RESULTS: We have developed staged spore isolation procedures for Arabidopsis and used Affymetrix ATH1 genome arrays to identify a total of 13,977 male gametophyte-expressed mRNAs, 9.7% of which were male-gametophyte-specific. The transition from bicellular to tricellular pollen was accompanied by a decline in the number of diverse mRNA species and an increase in the proportion of male gametophyte-specific transcripts. Expression profiles of regulatory proteins and distinct clusters of coexpressed genes were identified that could correspond to components of gametophytic regulatory networks. Moreover, integration of transcriptome and experimental data revealed the early synthesis of translation factors and their requirement to support pollen tube growth. CONCLUSIONS: The progression from proliferating microspores to terminally differentiated pollen is characterized by large-scale repression of early program genes and the activation of a unique late gene-expression program in maturing pollen. These data provide a quantum increase in knowledge concerning gametophytic transcription and lay the foundations for new genomic-led studies of the regulatory networks and cellular functions that operate to specify male gametophyte development