Ozone Contamination in Aircraft Cabins. Appendix B: Overview papers. Flight 8 planning to avoid high ozone

The problem of preventing cabin ozone from exceeding a given standard was investigated. Statistical analysis of vertical distribution of ozone is summarized. The cost, logistics, maintenance, ability to forecast ozone, and avoiding high ozone concentrations are presented. Filtering approaches and the requirements to remove ozone toxicity are discussed

Comparison of periodic and other characteristics of geomagnetic and meterological rocket data

The temporal variations in stratospheric winds and temperatures with the geomagnetic field elements were compared. From a periodic analysis of the geomagnetic field elements the amplitude and phase of the quasibiennial, annual, and semiannual waves are given for stations from 1 degree S to 89 degree N. These results are then compared with corresponding waves reported in rocketsonde wind and temperature data. The annual waves are found to be coupled as a result of the annual variation in the dynamo effect of the wind in the lower ionosphere. The semiannual waves are also found to be coupled and three possible causes for the extra tropical stratospheric semiannual wind wave are discussed. Time variance spectra for the interval from 4 days to 44 days in both zonal winds and horizontal geomagnetic field intensity are compared for years when major midwinter warmings occur and years when only minor warmings occur. The noted differences are suggested to arise from upward propagating planetary waves which are absorbed or refracted in varying amounts depending on the prevailing circulation

Periodic variations stratospheric temperature from 20-65 km at 80 deg N to 30 deg S

Results for a seasonally varying diurnal tide in temperature at Churchill are presented, and possible significant aliasing of longer period waves by this tide is discussed. A diurnal tide whose amplitude and phase are coherent throughout the year is found to have little effect on periodic amplitudes other than the long-term mean, because most rocketsonde observations are taken near the same local time each day. Errors in periodic components arising from lack of solar radiation corrections are found to be largest for the long-term mean with a small influence noted in the annual wave's amplitude. Spatial variations of the amplitudes and phases of long-period waves are examined through the use of height-latitude sections, 20-65 km, at 80 deg N to 30 deg S. The quasi-biennial oscillation and semiannual waves have tropical maxima of 2 and 3C near 30 and 40 km respectively. The annual wave's maximum is over 22C near 45 km at 70 deg N and the terannual wave's maximum is over 6C near 55 km at 80 deg N. The semiannual wave has to polar maxima: 7C near 75 deg N at 32 km and 3C above 60 km north of 35 deg N

Periodic variations in stratospheric meridional wind from 20-65 km, at 80 deg N to 8 deg S

The variability of stratospheric meridional winds is examined in both space and time. Height-latitude sections for January along 70 deg E and 90 deg W show a divergence zone above 50 km near 60 deg N and an intense convergence zone 40 km near 50 deg N over North America. This latter structure, with southward winds in the Arctic and northward winds at mid-latitudes over North America, persists from October through April. Tidal winds dominate all other circulation features in summer at all latitudes, and throughout the year at low latitudes. To help understand the observed patterns of variability, long-term periodic features are analyzed. The quasi-biennial oscillation, annual wave, and four-month wave have amplitudes of about 10, 20, and 10 m/sec respectively in the Arctic near 45 km. The phase of the annual wave changes by nearly 180 deg in a narrow zone near 45 deg N. The semiannual wave has an amplitude of 10 m/sec. 50 deg N above 50 km equinoctial phase dates in the region of maximum amplitude. This polar semiannual wave corresponds closely to that previously found in the zonal wind

Stratospheric circulation studies based on Tiros 7, 15-micron data Final report

Stratospheric temperature distribution data based on Tiros 7 radiometer dat

The effect of thermal anisotropies during crystallization in phase-change recording media

types: ArticleCopyright © 2008 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Journal of Applied Physics 104 (2008) and may be found at http://dx.doi.org/10.1063/1.2968447The problem discussed is the significance of anisotropies in the thermal parameters of different phases of phase-change materials as used for data storage purposes during recording. The particular phase change in interest is from the amorphous-to-crystalline state. Applying the method of correlation moment analysis produced upper estimators for the time dependence of the width of the crystalline mark and the time at which phase change ceases based on the heat flow process alone. These upper estimators are closed-form analytical expressions that can be used to estimate the recording resolution for any general spatial profile of initial temperature in the medium. This analysis showed that, up to a first order, the specific heat anisotropies have considerably less influence on the heat flow than the thermal conductivity differences. In general, for the material parameters used in phase-change data storage applications, the theory showed that the anisotropy in thermal parameters can be neglected. (C) 2008 American Institute of Physics

Mild clinical course of covid-19 in 3 patients receiving therapeutic monoclonal antibodies targeting c5 complement for hematologic disorders

© Am J Case Rep, 2020. Objective: Rare co-existance of disease or pathology Background: Patients receiving immunosuppressive therapies might be more susceptible to COVID-19. Conversely, an exaggerated inflammatory response to the SARS-CoV-2 infection might be blunted by certain forms of immunosuppression, which could be protective. Indeed, there are data from animal models demonstrating that complement may be a part of the pathophysiology of coronavirus infections. There is also evidence from an autopsy series demonstrating complement deposition in the lungs of patients with COVID-19. This raises the question of whether patients on anti-complement therapy could be protected from COVID-19. Case Reports: Case 1 is a 39-year-old woman with an approximately 20-year history of paroxysmal nocturnal hemoglobinuria (PNH), who had recently been switched from treatment with eculizumab to ravulizumab prior to SARS-CoV-2 infection. Case 2 is a 54-year-old woman with a cadaveric renal transplant for lupus nephritis, complicated by thrombotic microangiopathy, who was maintained on eculizumab, which she started several months before she developed the SARS-CoV-2 infection. Case 3 is a 60-year-old woman with a 14-year history of PNH, who had been treated with eculizumab since 2012, and was diagnosed with COVID-19 at the time of her scheduled infusion. All 3 patients had a relatively mild course of COVID-19. Conclusions: We see no evidence of increased susceptibility to SARS-CoV-2 in these patients on anti-complement therapy, which might actually have accounted for the mild course of infection. The effect of anti-complement therapy on COVID-19 disease needs to be determined in clinical trials

A Hot Helium Plasma in the Galactic Center Region

Recent X-ray observations by the space mission Chandra confirmed the astonishing evidence for a diffuse, hot, thermal plasma at a temperature of 9. $10^7$ K (8 keV) found by previous surveys to extend over a few hundred parsecs in the Galactic Centre region. This plasma coexists with the usual components of the interstellar medium such as cold molecular clouds and a soft (~0.8 keV) component produced by supernova remnants, and its origin remains uncertain. First, simple calculations using a mean sound speed for a hydrogen-dominated plasma have suggested that it should not be gravitationally bound, and thus requires a huge energy source to heat it in less than the escape time. Second, an astrophysical mechanism must be found to generate such a high temperature. No known source has been identified to fulfill both requirements. Here we address the energetics problem and show that the hot component could actually be a gravitationally confined helium plasma. We illustrate the new prospects this opens by discussing the origin of this gas, and by suggesting possible heating mechanisms.Comment: 9 pages, accepted for publication in APJ