Analyses of the stress field in southeastern France from earthquake focal mechanisms

Due to the apparent deformation field heterogeneity, the stress regimes around the Provence block, from the fronts of the Massif Central and Alpine range up to the Ligurian Sea, were not well defined. To improve the understanding of the SE France stress field, we determine new earthquake focal mechanisms and we compute the present-day stress states by inversion of the 89 available focal mechanisms around the Provence domain, including the 17 new ones calculated in the current study. This study provides evidence of 6 different deformation domains around the Provence block with different tectonic regimes. On a regional scale, we identify three zones characterised by significantly different stress regimes: a western one affected by an extensional stress (normal faulting) regime, a southeastern one characterised by a compressional stress (reverse to strike-slip faulting) regime with NNW- to WNW-trending σ1 and a northeastern one, i.e., the Digne nappe front, marked by an NE-trending compression. Note that the Digne nappe back domain is controlled by an extensional regime that is deforming the western alpine core. This extensional regime could be a response to buoyancy forces related to the Alpine high topography. The stress regimes in the southeast of the Argentera Massif and around the Durance fault are consistent with a coherent NNW-trending σ1 that implies a left-lateral component of the active reverse oblique-slip of the Moyenne Durance Fault. In the Rhone Valley, an E-trending extension characterises the tectonic regime that implies a normal component of the present-day Nîmes fault displacement. This study provides evidence for short-scale variation of the stress states that reflect abrupt change in the boundary force influences on upper crustal fragments (blocks). These spatial stress changes around the Provence block result from the coeval influence of forces applied at both its extremities, i.e., in the north-east, the Alpine front push and in the southeast, the northward African plate drift. Besides these boundary forces, the influence of the mantle plume under the Massif Central can be superimposed along the western block boundary

Colloidal brazil nut effect in sediments of binary charged suspensions

Equilibrium sedimentation density profiles of charged binary colloidal suspensions are calculated by computer simulations and density functional theory. For deionized samples, we predict a colloidal ``brazil nut'' effect: heavy colloidal particles sediment on top of the lighter ones provided that their mass per charge is smaller than that of the lighter ones. This effect is verifiable in settling experiments.Comment: 4 pages, 4 figure

Environmental and socio-economic consequences of forest carbon payments in Bolivia: Results of the OSIRIS-Bolivia model

Bolivia has significant potential to abate climate change by reducing deforestation. This opportunity presents economic and environmental tradeoffs. While these tradeoffs have been hotly debated, they have as yet been the subject of little quantitative analysis. We introduce the OSIRIS-Bolivia model to provide a quantitative basis for decision-making. OSIRIS-Bolivia is an Excel-based tool for analyzing the potential effects of incentive payments to reduce emissions from deforestation (REDD) in Bolivia. It is based on a spatial econometric model of deforestation in Bolivia during the period 2001-2005, and uses information on forest cover, deforestation rates, geographical conditions, and drivers of deforestation, including agricultural opportunity costs, for more than 120,000 pixels covering the whole country. OSIRIS-Bolivia is based on a partial equilibrium model in which reductions in deforestation in one region reduce the supply of agricultural products to the domestic market, which in turn causes an increase in the price of agricultural products, making conversion of land to agriculture more attractive and thus stimulating an increase in deforestation in other regions (leakage). The model can help answer questions such as: Where in Bolivia are carbon incentive payments most likely to result in reduced deforestation? Who are most likely to benefit from REDD? How much money will it take to reduce deforestation by a given amount? To what extent might transaction costs or preferences for agricultural income undermine the goals of the REDD program

Aging and memory properties of topologically frustrated magnets

The model 2d kagome system (H3O)Fe3(SO4)2(OH)6 and the 3d pyrochlore Y2Mo2O7 are two well characterized examples of low-disordered frustrated antiferromagnets which rather then condensing into spin liquid have been found to undergo a freezing transition with spin glass-like properties. We explore more deeply the comparison of their properties with those of spin glasses, by the study of characteristic rejuvenation and memory effects in the non-stationary susceptibility. While the pyrochlore shows clear evidence for these non-trivial effects, implying temperature selective aging, that is characteristic of a wide hierarchical distribution of equilibration processes, the kagome system does n not show clearly these effects. Rather, it seems to evolve towards the same final state independently of temperature.Comment: submitted for the proceedings of the 46th MMM conference (Seattle, 2001

The relative influences of disorder and of frustration on the glassy dynamics in magnetic systems

The magnetisation relaxations of three different types of geometrically frustrated magnetic systems have been studied with the same experimental procedures as previously used in spin glasses. The materials investigated are Y$_2$Mo$_2$O$_7$ (pyrochlore system), SrCr$_{8.6}$Ga$_{3.4}$O$_{19}$ (piled pairs of Kagom\'e layers) and (H$_3$O)Fe$_3$(SO$_4$)$_2$(OH)$_6$ (jarosite compound). Despite a very small amount of disorder, all the samples exhibit many characteristic features of spin glass dynamics below a freezing temperature $T_g$, much smaller than their Curie-Weiss temperature $\theta$. The ageing properties of their thermoremanent magnetization can be well accounted for by the same scaling law as in spin glasses, and the values of the scaling exponents are very close. The effects of temperature variations during ageing have been specifically investigated. In the pyrochlore and the bi-Kagom\'e compounds, a decrease of temperature after some waiting period at a certain temperature $T_p$ re-initializes ageing and the evolution at the new temperature is the same as if the system were just quenched from above $T_g$. However, as the temperature is raised back to $T_p$, the sample recovers the state it had previously reached at that temperature. These features are known in spin glasses as rejuvenation and memory effects. They are clear signatures of the spin glass dynamics. In the Kagom\'e compound, there is also some rejuvenation and memory, but much larger temperature changes are needed to observe the effects. In that sense, the behaviour of this compound is quantitatively different from that of spin glasses.Comment: latex VersionCorrigee4.tex, 4 files, 3 figures, 5 pages (Proceedings of the International Conference on Highly Frustrated Magnetism (HFM2003), August 26-30, 2003, Institut Laue Langevin (ILL), Grenoble, France

Recent tectonic reorganization of the Nubia-Eurasia convergent 2 boundary heading for the closure of the western Mediterranean

: In the western Mediterranean area, after a long period (late Paleogene-Neogene) of Nubian northward subduction beneath Eurasia, subduction is almost ceased as well as convergence accommodation in the subduction zone. With the progression of Nubia-Eurasia convergence, a tectonic reorganization is therefore necessary to accommodate future contraction. Previously-published tectonic, seismological, geodetic, tomographic, and seismic reflection data (integrated by some new GPS velocity data) are reviewed to understand the reorganization of the convergent boundary in the western Mediterranean. Between northern Morocco, to the west, and northern Sicily, to the east, contractional deformation has shifted from the former subduction zone to the margins of the two backarc oceanic basins (Algerian-Liguro-Provençal and Tyrrhenian basins) and it is now active in the south-Tyrrhenian (northern Sicily), northern Liguro-Provençal, Algerian, and Alboran (partly) margins. Compression and basin inversion has propagated in a scissor-like manner from the Alboran (c. 8 Ma) to the Tyrrhenian (younger than c. 2 Ma) basins following a similar propagation of the subduction cessation and slab breakoff, i.e., older to the west and younger to the east. It follows that basin inversion is rather advanced in the Algerian margin, where a new southward subduction seems to be in its very infant stage, while it has still to properly start in the Tyrrhenian margin, where contraction has resumed at the rear of the fold-thrust belt and may soon invert the Marsili oceanic basin. GPS-derived strain rates higher in the Tyrrhenian margin than in the Algerian boundary suggest that this latter manner of contraction accommodation (contraction resumption at the rear of the orogenic wedge) is more efficient than subduction inception and basin inversion along newly-generated reverse faults (Algeria), but the differential strain rates may also be explained with the heterogeneous distribution of GPS stations. Part of the contractional deformation may have shifted toward the north in the Liguro-Provençal basin possibly because of its weak rheological properties compared with the area between Tunisia and Sardinia, where no oceanic crust occurs and seismic deformation is absent or limited compared with the adjacent strands of the Nubia-Eurasia boundary. The tectonic reorganization of the Nubia-Eurasia boundary in the study area is still strongly controlled by the inherited tectonic fabric and rheological attributes, which are both discontinuous and non-cylindrical along the boundary. These features prevent, at present, the development of long and continuous thrust faults. In an extreme and approximate synthesis, the evolution of the western Mediterranean is inferred as being similar to a Wilson Cycle in the following main steps: (1) northward Nubian subduction with Mediterranean backarc extension (since ~35 Ma); (2) progressive cessation, from west to east, of Nubian main subduction (since ~15 Ma); (3) progressive compression, from west to east, in the former backarc domain and consequent basin inversion (since ~8-10 Ma); (4) possible future subduction of former backarc basins

Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer\u27s disease and aged brains: increased levels correlate with neuropathology.

Progranulin (PGRN) is a protein encoded by the GRN gene with multiple identified functions including as a neurotrophic factor, tumorigenic growth factor, anti-inflammatory cytokine and regulator of lysosomal function. A single mutation in the human GRN gene resulting in reduced PGRN expression causes types of frontotemporal lobar degeneration resulting in frontotemporal dementia. Prosaposin (PSAP) is also a multifunctional neuroprotective secreted protein and regulator of lysosomal function. Interactions of PGRN and PSAP affect their functional properties. Their roles in Alzheimer\u27s disease (AD), the leading cause of dementia, have not been defined. In this report, we examined in detail the cellular expression of PGRN in middle temporal gyrus samples of a series of human brain cases (n = 45) staged for increasing plaque pathology. Immunohistochemistry showed PGRN expression in cortical neurons, microglia, cerebral vessels and amyloid beta (Aβ) plaques, while PSAP expression was mainly detected in neurons and Aβ plaques, and to a limited extent in astrocytes. We showed that there were increased levels of PGRN protein in AD cases and corresponding increased levels of PSAP. Levels of PGRN and PSAP protein positively correlated with amyloid beta (Aβ), with PGRN levels correlating with phosphorylated tau (serine 205) levels in these samples. Although PGRN colocalized with lysosomal-associated membrane protein-1 in neurons, most PGRN associated with Aβ plaques did not. Aβ plaques with PGRN and PSAP deposits were identified in the low plaque non-demented cases suggesting this was an early event in plaque formation. We did not observe PGRN-positive neurofibrillary tangles. Co-immunoprecipitation studies of PGRN from brain samples identified only PSAP associated with PGRN, not sortilin or other known PGRN-binding proteins, under conditions used. Most PGRN associated with Aβ plaques were immunoreactive for PSAP showing a high degree of colocalization of these proteins that did not change between disease groups. As PGRN supplementation has been considered as a therapeutic approach for AD, the possible involvement of PGRN and PSAP interactions in AD pathology needs to be further considered

Structural Controls on Crustal Fluid Circulation and Hot Spring Geochemistry Above a Flat‐Slab Subduction Zone, Peru

Hot spring geochemistry from the Cordillera Blanca and Cordillera Huayhuash, Peru, reveal the influence of crustal‐scale structures on geothermal fluid circulation in an amagmatic region located above a flat‐slab subduction zone. To test the influence of contrasting modes of faulting in these regions, springs were targeted along the Cordillera Blanca detachment fault, within its hanging wall, in the footwall of the detachment, and in the Cordillera Huayhuash. Hot springs along the Cordillera Blanca detachment fault zone are associated with recent extension and normal faulting, and those in its footwall and the Cordillera Huayhuash are located in the Marañon fold and thrust belt where compressional structures dominate. Springs along and in the hanging wall of the Cordillera Blanca detachment fault yield brackish‐saline, alkaline‐chloride waters, with oxygen, hydrogen, carbon, and chlorine stable isotope values that suggest mixing between meteoric groundwater and saline brine affected by high water‐rock interaction. Geothermometry reservoir temperature estimates (RTEs) of 91–226°C indicate maximum flow path depths of 8.7 or 11 km, depending on geothermal gradient, associated with the Cordillera Blanca detachment fault. In contrast, springs in the footwall and in the Cordillera Huayhuash exhibit a wide range of water types with an isotopic affinity to meteoric water, suggesting a greater influence from shallow groundwater and less water‐rock interaction. For these springs, RTEs of 40–98°C correspond to much shallower circulation (1.6–4 km). Results indicate that the Cordillera Blanca detachment system accommodates significantly deeper circulation of crustal fluids compared to other regional compressional structures

Mycobacterium tuberculosis ClpP Proteases Are Co-transcribed but Exhibit Different Substrate Specificities

PMCID: PMC3613350This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

The Grosmarin experiment

The GROSMARIN (which stands for GrandROSMARIN) cruise is proposed by UMR Géosciences Azur (with fellow french and italian research groups). Its goals are to better characterize active structures along this zone and to assess the resulting seismic hazard in a sort of continuation with respect to the MALISAR experiment, which has already surveyed some active structures through shallow observations. The GROSMARIN cruise is in fact the necessary counterpart to characterize them at depth