Activities of organic farmers succeeding in reducing lameness in dairy cows

Sixty-seven organic producers were among 189 dairy farmers completing the “Healthy Feet Project” in the UK. This aimed to reduce lameness in dairy herds by implementing existing knowledge. Participants received input at two levels: monitoring alone, or monitoring with extra support through a single veterinary advisory visit, annual visits from a trained non-veterinary facilitator and materials and contacts to encourage change. On average lameness on organic farms reduced by 12 percentage points over the three year period. On the farms achieving the greatest reduction,the most common changes were improvements to tracks and cubicle comfort, and more frequent footbathing or foot trimming. Practices to improve foot cleanliness, such as more frequent removal of slurry, were less often adopted. Further progress might be achieved by improvements of foot hygiene. Several farms with low lameness that reduced prevalence further improved their handling facilities and treated cows more promptly

Experiences of Statelessness and Refugee Protection: Exploring the "Rohingya Life" in Sydney, Australia

Australia has two systems for refugees, one is the official refugee resettlement system, a coordinated approach between Australia and the United Nations High Commission for Refugees (UNHCR). The other system is government responses to irregular arrivals of people seeking asylum, most notably those who come by boat. Over the last 20 years, people who arrive informally are placed in immigration detention, deported or given temporary forms of refugee protection. In this system, some people are stateless, with no country to return to, no citizenship or nationality to protect them. This research draws on the lived experience of the stateless Rohingya refugee community in Sydney, Australia, to explore the intersection between statelessness and refugee protection. Using anti-oppressive social work theory and a human rights approach, the research aims include developing an understanding of the lived experience of statelessness; identifying the barriers to successful settlement and the impact of prolonged temporary status on stateless Rohingya people in the Australian community. This research uses participatory action research methodology, working with the Rohingya community. The key finding of this research identifies that statelessness dominates and dictates all aspects of life and inevitability infiltrates a person’s sense of identity, leading to internalised oppression, affecting all aspects of life including the interaction with time and sense of belonging. Prolonged temporariness and the continuation of statelessness also disrupts the settlement experience and significantly effects individual mental health. While stateless Rohingya refugees have a heightened vulnerability, they are not without agency. Anti-oppressive theory considers the distribution of power and how marginalised groups have the power to resist combat oppression through community building and action. Within the context of resistance, this research identified through the voices of the Rohingya, a strong drive for community development and examples of how a marginalised and oppressed group can create autonomy, agency and liveable spaces. Ultimately, temporary forms of refugee protection exacerbate the vulnerabilities of statelessness, particularly manifest in the loss of community, belonging and internalised oppression. The findings of this research have implications for understanding statelessness in the global context and how statelessness interacts with refugeehood and refugee protection

Barriers and Opportunities for Concussion Communication and Management in Youth Sports: A qualitative study

To identify opportunities to improve coach-athlete communication, this study examined young athletes’ perceptions and concerns about concussion, as well as their information needs. A qualitative data collection approach, based on the grounded theory methodology, was utilized. Six virtual focus groups were conducted with 17 male and female athletes’ ages 12 to 18 years. Results indicated that athletes were concerned about the potential long-term effects of a concussion. Athletes described multiple barriers that interfere with concussion reporting, including: being unfamiliar with concussion signs and symptoms, perceived pressure from teammates, concerns of interference that concussion reporting can have on gameplay, and a lack of focus on concussion during play. To help address these, participants expressed an interest in hearing frequently and directly, such as during a pre-game or practice huddle, from coaches about concussion and how to prevent this injury. The results demonstrate that concussion education programs can consider promoting messages for coaches to deliver to athletes about concussion prevention strategies and the benefits of concussion reporting on an athlete’s long-term health

Urban blue acupuncture:A protocol for evaluating a complex landscape design intervention to improve health and wellbeing in a coastal Ccommunity

Within the BlueHealth project, funded under the Horizon 2020 European Union researchframework, a number of targeted experimental design interventions were used to test the effectand impact of planning and design on encouraging people to use various blue spaces. Complexinterventions were implemented and evaluations before and after each were made using a set oftools which triangulate with each other—a site assessment tool, a behaviour observation tool, aquestionnaire survey (including an economic evaluation) and qualitative interviews. The theoreticalbasis for the research is that of affordances, and the projects each involved modest changes to thelandscape using the approach of “urban acupuncture” where a small intervention can potentiallyhave an effect out of all proportion to the investment. This paper is a protocol paper and describesthe research strategy and methodology in detail for one of the intervention sites, located in Plymouthin the UK. The aim is to present the methodology as a whole so as to act as (a) a reference frameworkfor the results of all the projects which will be reported separately in a series of research articles onceall the results are in and analysed and (b) a useful reference for other researchers wishing to carry outsuch complex projects and where a comprehensive presentation of the strategy and methodology isunavailable. We offer this protocol for reference, for critique and for inspiration to those following us

Pulmonary adenocarcinoma in two alpacas (Vicugna pacos)

We describe here two cases of pulmonary neoplasia in alpacas: case 1 was a 19‐year‐old female huacaya alpaca that was submitted to investigate sudden death with possible previous weight loss. Gross and histological examination revealed changes consistent with primary lepidic‐type pulmonary adenocarcinoma (previously bronchioalveolar carcinoma) with metastases to the thorax and abdomen. Case 2 was a six‐year‐old male castrated Suri alpaca with a 3‐week history of weight loss and inappetance that was euthanased following a short period of recumbency and respiratory signs. Gross and histological features in this case were consistent with a diagnosis of metastatic adenocarcinoma affecting the lungs and lymph nodes. Masses from both alpacas were further characterised using immunohistochemistry for thyroid transcription factor 1 (TTF‐1), pan cytokeratin AE1/AE3 and vimentin. We show that histological subtype and TTF‐1 and AE1/AE3 immunoreactivity can be used to differentiate primary and metastatic pulmonary adenocarcinomas in the lungs of alpacas

Physical activity in pregnancy: A qualitative study of the beliefs of overweight and obese pregnant women

Background Whilst there has been increasing research interest in interventions which promote physical activity during pregnancy few studies have yielded detailed insights into the views and experiences of overweight and obese pregnant women themselves. The qualitative study described in this paper aimed to: (i) explore the views and experiences of overweight and obese pregnant women; and (ii) inform interventions which could promote the adoption of physical activity during pregnancy. Methods The study was framed by a combined Subtle Realism and Theory of Planned Behaviour (TPB) approach. This enabled us to examine the hypothetical pathway between beliefs and physical activity intentions within the context of day to day life. The study sample for the qualitative study was chosen by stratified, purposive sampling from a previous study of physical activity measurements in pregnancy. Research participants for the current study were recruited on the basis of Body Mass Index (BMI) at booking and parity. Semi-structured, in-depth interviews were conducted with 14 overweight and obese pregnant women. Data analysis was undertaken using a Framework Approach and was informed by TPB. Results Healthy eating was often viewed as being of greater importance for the health of mother and baby than participation in physical activity. A commonly cited motivator for maintaining physical activity during pregnancy is an aid to reducing pregnancy-related weight gain. However, participants often described how they would wait until the postnatal period to try and lose weight. A wide range of barriers to physical activity during pregnancy were highlighted including both internal (physical and psychological) and external (work, family, time and environmental). The study participants also lacked access to consistent information, advice and support on the benefits of physical activity during pregnancy. Conclusions Interventions to encourage recommended levels of physical activity in pregnancy should be accompanied by accessible and consistent information about the positive effects for mother and baby. More research is required to examine how to overcome barriers to physical activity and to understand which interventions could be most effective for overweight/obese pregnant women. Midwives should be encouraged to do more to promote activity in pregnancy

Modeling the extracellular matrix in cell migration and morphogenesis:a guide for the curious biologist

The extracellular matrix (ECM) is a highly complex structure through which biochemical and mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a scaffold, providing structural support to cells as well as points of potential attachment. Although the ECM is a well-studied structure, its role in many biological processes remains difficult to investigate comprehensively due to its complexity and structural variation within an organism. In tandem with experiments, mathematical models are helpful in refining and testing hypotheses, generating predictions, and exploring conditions outside the scope of experiments. Such models can be combined and calibrated with in vivo and in vitro data to identify critical cell-ECM interactions that drive developmental and homeostatic processes, or the progression of diseases. In this review, we focus on mathematical and computational models of the ECM in processes such as cell migration including cancer metastasis, and in tissue structure and morphogenesis. By highlighting the predictive power of these models, we aim to help bridge the gap between experimental and computational approaches to studying the ECM and to provide guidance on selecting an appropriate model framework to complement corresponding experimental studies

A systematic scoping review of health-promoting interventions for contact centre employees examined through a behaviour change wheel lens

Purpose: Social determinants of health and poor working conditions contribute to excessive sickness absence and attrition in contact centre advisors. With no recent review conducted, the current scoping review is needed to investigate the volume, effectiveness, acceptability, and feasibility of health-promoting interventions for contact centre advisors. This will inform the adoption and implementation of evidence-based practice, and future research. Methods: Searches conducted across four databases (MEDLINE, PsycInfo, CINAHL, Web of Science) and reference checking in February 2023 identified health-promoting interventions for contact centre advisors. Extracted and coded data from eligible interventions were systematically synthesised using the nine intervention functions of the Behaviour Change Wheel and behaviour change technique taxonomy. Results: This scoping review identified a low number of high quality and peer-reviewed health-promoting intervention studies for contact centre advisors (28 studies since 2002). Most interventions were conducted in high-income countries with office-based advisors, predominantly using environmental restructuring and training strategies to improve health. Most interventions reported positive effectiveness results for the primary intended outcome, which were broadly organised into: i) health behaviours (sedentary behaviour, physical activity, smoking); ii) physical health outcomes (musculoskeletal health, visual health, vocal health, sick building syndrome); iii) mental health outcomes (stress, job control, job satisfaction, wellbeing). Few interventions evaluated acceptability and feasibility. Conclusion: There is little evidence on the effectiveness, acceptability, and feasibility of health-promoting interventions for contact centre advisors. Evidence is especially needed in low-to-middle income countries, and remote/hybrid, nightshift and older advisors, and advisors living with disability

Research priorities for the management of broken bones of the upper limb in people over 50: A UK priority setting partnership with the James Lind Alliance

Objective. To determine research priorities for the management of broken bones of the upper limb in people over 50 which represent the shared priorities of patients, their families, carers and healthcare professionals. Design/setting. A national (UK) research priority-setting partnership. Participants. People aged 50 and over who have experienced a fracture of the upper limb; carers involved in their care; family and friends of patients; healthcare professionals involved in the treatment of these patients. Methods. Using a multiphase methodology in partnership with the James Lind Alliance over 15 months (September 2017 – December 2018), a national scoping survey asked respondents to submit their research uncertainties. These were amalgamated into a smaller number of research questions. The existing evidence was searched to ensure that the questions had not already been answered. A second national survey asked respondents to prioritise the research questions. A final shortlist of 25 questions was taken to a multistakeholder workshop where a consensus was reached on the top 10 priorities. Results. There were 1898 original uncertainties submitted by 328 respondents to the first survey. These original uncertainties were refined into 51 research questions of which 50 were judged to be true uncertainties following a review of the research evidence. There were 209 respondents to the second (interim prioritisation) survey. The top 10 priorities encompass a broad range of uncertainties in management and rehabilitation of upper limb fractures. Conclusions. The top 10 UK research priorities highlight uncertainties in how we assess outcomes, provide information, achieve pain control, rationalise surgical intervention, optimise rehabilitation and provide psychological support. The breadth of these research areas highlights the value of this methodology. This work should help to steer research in this area for the next 5-10 years and the challenge for researchers now is to refine and deliver answers to these research priorities