Harvest-based Monitoring in the Inuvialuit Settlement Region: Steps for Success

We define harvest-based monitoring as the long-term collection of data or samples from a subsistence harvest in order to reveal, document, and track changes in biophysical resources. Our objective is to describe five practical steps that have guided us over the past two decades during delivery of harvest-based monitoring studies in the Inuvialuit Settlement Region (ISR). Studies have usually been designed to detect (but not necessarily explain) change, to involve local harvesters, and to incorporate indigenous and science-based knowledge. The five steps are to (1) formulate a scientific research or long-term monitoring question that can reasonably be answered by analyzing data from harvests or harvested specimens, (2) design the program according to scientific and indigenous protocols, (3) determine respective partner roles for delivery of the field program, (4) conduct the field work, and (5) analyze data and communicate results. At all steps, it is important to ensure that science and indigenous knowledge partners respect and trust each other’s skills, knowledge, and abilities; that regular communication is fostered; and that provisions are in place to monitor progress. The credible blending of indigenous and scientific views and skills improves the likelihood of ultimately understanding the resource, its habitats, and its inherent ecological relationships.Key words: harvest-based monitoring, Inuvialuit Settlement Region, collaborative research, participatory researchNous définissons la surveillance des captures comme la collecte à long terme de données ou d’échantillons provenant des captures ou récoltes de subsistance et ce, dans le but de révéler, de documenter et de suivre les changements caractérisant les ressources biophysiques. Notre objectif consiste à décrire cinq étapes pratiques qui nous ont servi de guides ces deux dernières décennies dans le cadre d’études de surveillance des captures dans la région désignée des Inuvialuit (RDI). Habituellement, les études sont conçues pour détecter (et non pas nécessairement pour expliquer) le changement, pour faire appel aux personnes faisant les captures dans la région et pour favoriser l’intégration des connaissances indigènes et scienti­fiques. Ces cinq étapes sont les suivantes : 1) formuler une question de recherche scientifique ou de surveillance à long terme à laquelle on peut raisonnablement répondre au moyen de l’analyse des données de captures ou des échantillons capturés; 2) concevoir un programme qui respecte les protocoles scientifiques et indigènes; 3) déterminer le rôle des partenaires respectifs en ce qui a trait à l’exécution du programme sur le terrain; 4) réaliser le travail sur le terrain; et 5) analyser les données puis communiquer les résultats. À toutes ces étapes, il est important de faire en sorte que les partenaires en matière de connaissances scientifiques et de connaissances indigènes respectent les compétences, les connaissances et les aptitudes de chacun, et se fassent confiance; que les partenaires communiquent régulièrement; et que des dispositions soient en place pour suivre les progrès. Le mélange crédible de points de vue et de compétences indigènes et scientifiques améliore la probabilité que l’on finisse par comprendre la ressource, ses habitats et ses relations écologiques inhérentes. Mots clés : surveillance des captures, région désignée des Inuvialuit, recherche collaborative, recherche participativ

Characterizing Entanglement Sources

We discuss how to characterize entanglement sources with finite sets of measurements. The measurements do not have to be tomographically complete, and may consist of POVMs rather than von Neumann measurements. Our method yields a probability that the source generates an entangled state as well as estimates of any desired calculable entanglement measures, including their error bars. We apply two criteria, namely Akaike's information criterion and the Bayesian information criterion, to compare and assess different models (with different numbers of parameters) describing entanglement-generating devices. We discuss differences between standard entanglement-verificaton methods and our present method of characterizing an entanglement source.Comment: This submission, together with the next one, supersedes arXiv:0806.416

Absorption in the Infrared of Surface Electromagnetic Waves by Adsorbed Molecules on a Copper Surface

Experimental Observations Have Been Made for the First Time that Surface Electromagnetic Wave (SEW) Spectroscopy Can Be Used to Measure the Infrared Spectra of Adsorbed Molecules and Very Thin Films on Metal Surfaces. using a Tunable CO2 Laser (9.2-10.8 Μm Wavelength), the 975 and the 1037 Cm-1 Resonances of 5-25 Å Thick Physiosorbed Benzene on Copper Were Observed. Broadening of These Resonances for the Thinnest Layers of Benzene Was Observed. Also SEW Spectroscopy and Ellipsometry Were Used to Study Thin Films of Cellulose Acetate (15-75 Å) on Copper. Further, It Was Shown that Film Thicknesses Determined by SEW Spectroscopy Are in Agreement with the Ellipso metric Thicknesses and that the SEW Method is More Sensitive for Very Thin (\u3c25 \u3eÅ) Films. Copyright © 1976 American Institute of Physics

Microbial Resistance Mechanisms to the Antibiotic and Phytotoxin Fusaric Acid

Fusaric acid (FA) produced by Fusarium oxysporum plays an important role in disease development in plants, including cotton. This non-specific toxin also has antibiotic effects on microorganisms. Thus, one expects a potential pool of diverse detoxification mechanisms of FA in nature. Bacteria and fungi from soils infested with Fusarium and from laboratory sources were evaluated for their ability to grow in the presence of FA and to alter the structure of FA into less toxic compounds.None of the bacterial strains were able to chemically modify FA. Highly FA resistant strains were found only in Gram-negative bacteria, mainly in the genus of Pseudomonas. The FA resistance of the Gram-negative bacteria was positively correlated with the number of predicted genes for FA efflux pumps present in the genome. Phylogenetic analysis of predicted FA resistance proteins (FUSC, an inner membrane transporter component of the efflux pump) revealed that FUSC proteins having high sequence identities with the functionally characterized FA resistance protein FusC or Fdt might be the major contributors of FA resistance. In contrast, most fungi converted FA to less toxic compounds regardless of the level of FA resistance they exhibited. Five derivatives were detected, and the detoxification of FA involved either oxidative reactions on the butyl side chain or reductive reactions on the carboxylic acid group. The production of these metabolites from widely different phyla indicates that resistance to FA by altering its structure is highly conserved. A few FA resistant saprophytic or biocontrol strains of fungi were incapable of altering FA, indicating a possible involvement of efflux transporters. Deployment of both efflux and derivatization mechanisms may be a common feature of fungal FA resistance

Einstein, incompleteness, and the epistemic view of quantum states

Does the quantum state represent reality or our knowledge of reality? In making this distinction precise, we are led to a novel classification of hidden variable models of quantum theory. Indeed, representatives of each class can be found among existing constructions for two-dimensional Hilbert spaces. Our approach also provides a fruitful new perspective on arguments for the nonlocality and incompleteness of quantum theory. Specifically, we show that for models wherein the quantum state has the status of something real, the failure of locality can be established through an argument considerably more straightforward than Bell's theorem. The historical significance of this result becomes evident when one recognizes that the same reasoning is present in Einstein's preferred argument for incompleteness, which dates back to 1935. This fact suggests that Einstein was seeking not just any completion of quantum theory, but one wherein quantum states are solely representative of our knowledge. Our hypothesis is supported by an analysis of Einstein's attempts to clarify his views on quantum theory and the circumstance of his otherwise puzzling abandonment of an even simpler argument for incompleteness from 1927.Comment: 18 pages, 8 figures, 1 recipe for cupcakes; comments welcom

In defense of the epistemic view of quantum states: a toy theory

We present a toy theory that is based on a simple principle: the number of questions about the physical state of a system that are answered must always be equal to the number that are unanswered in a state of maximal knowledge. A wide variety of quantum phenomena are found to have analogues within this toy theory. Such phenomena include: the noncommutativity of measurements, interference, the multiplicity of convex decompositions of a mixed state, the impossibility of discriminating nonorthogonal states, the impossibility of a universal state inverter, the distinction between bi-partite and tri-partite entanglement, the monogamy of pure entanglement, no cloning, no broadcasting, remote steering, teleportation, dense coding, mutually unbiased bases, and many others. The diversity and quality of these analogies is taken as evidence for the view that quantum states are states of incomplete knowledge rather than states of reality. A consideration of the phenomena that the toy theory fails to reproduce, notably, violations of Bell inequalities and the existence of a Kochen-Specker theorem, provides clues for how to proceed with this research program.Comment: 32 pages, REVTEX, based on a talk given at the Rob Clifton Memorial Conference, College Park, May 2003; v2: minor modifications throughout, updated reference

An inducible CiliaGFP mouse model for in vivo visualization and analysis of cilia in live tissue

BACKGROUND: Cilia are found on nearly every cell type in the mammalian body, and have been historically classified as either motile or immotile. Motile cilia are important for fluid and cellular movement; however, the roles of non-motile or primary cilia in most tissues remain unknown. Several genetic syndromes, called the ciliopathies, are associated with defects in cilia structure or function and have a wide range of clinical presentations. Much of what we know about the formation and maintenance of cilia comes from model systems like C. elegans and Chalmydomonas. Studies of mammalian cilia in live tissues have been hampered by difficulty visualizing them. RESULTS: To facilitate analyses of mammalian cilia function we generated an inducible Cilia(GFP) mouse by targeting mouse cDNA encoding a cilia-localized protein somatostatin receptor 3 fused to GFP (Sstr3::GFP) into the ROSA26 locus. In this system, Sstr3::GFP is expressed from the ubiquitous ROSA26 promoter after Cre mediated deletion of an upstream Neo cassette flanked by lox P sites. Fluorescent cilia labeling was observed in a variety of live tissues and after fixation. Both cell-type specific and temporally regulated cilia labeling were obtained using multiple Cre lines. The analysis of renal cilia in anesthetized live mice demonstrates that cilia commonly lay nearly parallel to the apical surface of the tubule. In contrast, in more deeply anesthetized mice the cilia display a synchronized, repetitive oscillation that ceases upon death, suggesting a relationship to heart beat, blood pressure or glomerular filtration. CONCLUSIONS: The ability to visualize cilia in live samples within the Cilia(GFP) mouse will greatly aid studies of ciliary function. This mouse will be useful for in vivo genetic and pharmacological screens to assess pathways regulating cilia motility, signaling, assembly, trafficking, resorption and length control and to study cilia regulated physiology in relation to ciliopathy phenotypes

Seven Steps Towards the Classical World

Classical physics is about real objects, like apples falling from trees, whose motion is governed by Newtonian laws. In standard Quantum Mechanics only the wave function or the results of measurements exist, and to answer the question of how the classical world can be part of the quantum world is a rather formidable task. However, this is not the case for Bohmian mechanics, which, like classical mechanics, is a theory about real objects. In Bohmian terms, the problem of the classical limit becomes very simple: when do the Bohmian trajectories look Newtonian?Comment: 16 pages, LaTeX, uses latexsy