191 research outputs found

    Montane lakes (lagoons) of the New England Tablelands Bioregion

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    The vegetation of montane lagoons of the New England Tablelands Bioregion, New South Wales is examined using flexible UPGMA analysis of frequency scores on all vascular plant taxa, charophytes and one liverworts. Seven communities are described: 1. Hydrocotyle tripartita – Isotoma fluviatilis – Ranunculus inundatus – Lilaeopsis polyantha herbfield; 2. Eleocharis sphacelata – Potamogeton tricarinatus sedgeland; 3. Eleocharis sphacelata – Utricularia australis – Isolepis fluitans, herbfield; 4. Utricularia australis – Nitella sonderi herbfield; 5. Eleocharis sphacelata – Utricularia australis – Ricciocarpus natans sedgeland; 6. Carex gaudichaudiana – Holcus lanatus – Stellaria angustifolia sedgeland; 7. Cyperus sphaeroides – Eleocharis gracilis – Schoenus apogon – Carex gaudichaudiana sedgeland. 58 lagoons were located and identified, only 28% of which are considered to be intact and in good condition. Two threatened species (Aldovandra vesiculosa and Arthaxon hispidus) and three RoTAP-listed taxa were encountered during the survey

    Empowering People with Disabilities to Prevent Violence and Abuse

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    Complete Digitized Text of Chapter 7 of the book Combating Violence & Abuse of People with Disabilities: A Call to Action by Nancy M. Fitzsimons.https://cornerstone.lib.mnsu.edu/books-fitzsimons-combating-violence/1008/thumbnail.jp

    Age Recognition in Adults With Intellectual Disabilities and Research Portfolio

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    The ability of children to classify accurately their own ages and the ages of others has been the subject of very limited research. However, the literature is largely in agreement on there being progressive increases with chronological age, though there is disagreement on the age at which the skill becomes well developed. The processes look similar in the field of adults with intellectual disabilities although this area is extremely under-researched. Key factors may include age, the degree of institutionalisation, developmental level and IQ. This paper presents the findings of a research study investigating the age recognition of self and others in a group of 20 intellectually disabled adults from within a major institution and the wider community. Measures of age recognition using photographs, as well as standardised measures of intellectual ability and social adaptive behaviour, were administered and correlations were found between the ability to recognise age in others and developmental age and also IQ. Success on the task of age discrimination appears to more likely if the IQ is around 60 - 65 or above and if the person shows social adaptive behaviour at an age equivalence of 8 to 9 years and over. Also included was a task in which only the discrimination of whether the photographs were of adults or children was required, and this proved to be a simpler process for the participants. This study also demonstrates some of the discriminative stimuli used by adults with intellectual disabilities to ascertain the approximate age of a person

    Enhanced Vascularization of Cultured Skin Substitutes Genetically Modified to Overexpress Vascular Endothelial Growth Factor11The authors declared in writing to have no conflict of interest.

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    Cultured skin substitutes have been used as adjunctive therapies in the treatment of burns and chronic wounds, but they are limited by lack of a vascular plexus. This deficiency leads to greater time for vascularization compared with native skin autografts and contributes to graft failure. Genetic modification of cultured skin substitutes to enhance vascularization could hypothetically lead to improved wound healing. To address this hypothesis, human keratinocytes were genetically modified by transduction with a replication incompetent retrovirus to overexpress vascular endothelial growth factor, a specific and potent mitogen for endothelial cells. Cultured skin substitutes consisting of collagen-glycosaminoglycan substrates inoculated with human fibroblasts and either vascular endothelial growth factor-modified or control keratinocytes were prepared, and were cultured in vitro for 21 d. Northern blot analysis demonstrated enhanced expression of vascular endothelial growth factor mRNA in genetically modified keratinocytes and in cultured skin substitutes prepared with modified cells. Furthermore, the vascular endothelial growth factor-modified cultured skin substitutes secreted greatly elevated levels of vascular endothelial growth factor protein throughout the entire culture period. The bioactivity of vascular endothelial growth factor protein secreted by the genetically modified cultured skin substitutes was demonstrated using a microvascular endothelial cell growth assay. Vascular endothelial growth factor-modified and control cultured skin substitutes were grafted to full-thickness wounds on athymic mice, and elevated vascular endothelial growth factor mRNA expression was detected in the modified grafts for at least 2 wk after surgery. Vascular endothelial growth factor-modified grafts exhibited increased numbers of dermal blood vessels and decreased time to vascularization compared with controls. These results indicate that genetic modification of keratinocytes in cultured skin substitutes can lead to increased vascular endothelial growth factor expression, which could prospectively improve vascularization of cultured skin substitutes for wound healing applications

    Ephemeral wetlands of the Pilliga Outwash, northwest NSW

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    The floristic composition and vegetation partitioning of the ephemeral wetlands of the Pilliga Outwash within the Pilliga National Park and Pilliga State Conservation Area (30˚30’S, 149˚22’E) on the North Western Plains of New South Wales are described. SPOT5 imagery was used to map 340 wetlands across the Pilliga Outwash. A total of 240 plots within 31 wetlands explored composition and species richness in relation to water depth and wetland size. The predominant community described is the species-rich herbfield of shallow basin wetlands, along with the structurally distinct but the less common sedgeland/herbfield of the deeper ‘tank’ wetlands and a single wetland with a floristically depauperate Diplachne fusca wet grassland. A total of 131 taxa were recorded including three species listed under the NSW Threatened Species Conservation Act (1995): Eriocaulon australasicum, Lepidium monoplocoides and Myriophyllum implicatum. New records for an additional six taxa were recorded for the North Western Plains. 11% of taxa were exotic in origin

    Nonhuman Primate Models Used to Study Pelvic Inflammatory Disease Caused by Chlamydia trachomatis

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    Pelvic inflammatory disease (PID) is a global health concern that is associated with significant morbidity and is a major cause of infertility. Throughout history animals have been used for anatomical studies and later as models of human disease. In particular, nonhuman primates (NHPs) have permitted investigations of human disease in a biologically, physiologically, and anatomically similar system. The use of NHPs as human PID models has led to a greater understanding of the primary microorganisms that cause disease (e.g., Chlamydia trachomatis and Neisseria gonorroheae), the pathogenesis of infection and its complications, and the treatment of people with PID. This paper explores historical and contemporary aspects of NHP modeling of chlamydial PID, with an emphasis on advantages and limitations of this approach and future directions for this research

    Strategies to Improve Adherence to Skin Self-examination and Other Self-management Practices in People at High Risk of Melanoma: A Scoping Review of Randomized Clinical Trials

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    Importance: Adherence, both in research trials and in clinical practice, is crucial to the success of interventions. There is limited guidance on strategies to increase adherence and the measurement and reporting of adherence in trials of melanoma self-management practices. Objective: This scoping review aimed to describe (1) strategies to improve adherence to self-management practices in randomized clinical trials of people at high risk of melanoma and (2) measurement and reporting of adherence data in these trials. Evidence review: Four databases, including MEDLINE, Embase, CENTRAL, and CINAHL, were searched from inception to July 2022. Eligible studies were randomized clinical trials of self-monitoring interventions for early detection of melanoma in people at increased risk due to personal history (eg, melanoma, transplant, dysplastic naevus syndrome), family history of melanoma, or as determined by a risk assessment tool or clinical judgment. Findings: From 939 records screened, 18 eligible randomized clinical trials were identified, ranging in size from 40 to 724 participants, using a range of adherence strategies but with sparse evidence on effectiveness of the strategies. Strategies were classified as trial design (n = 15); social and economic support (n = 5); intervention design (n = 18); intervention and condition support (n = 10); and participant support (n = 18). No strategies were reported for supporting underserved groups (eg, people who are socioeconomically disadvantaged, have low health literacy, non-English speakers, or older adults) to adhere to self-monitoring practices, and few trials targeted provider (referring to both clinicians and researchers) adherence (n = 5). Behavioral support tools included reminders (n = 8), priority-setting guidance (n = 5), and clinician feedback (n = 5). Measurement of adherence was usually by participant report of skin self-examination practice with some recent trials of digital interventions also directly measuring adherence to the intervention through website or application analytic data. Reporting of adherence data was limited, and fewer than half of all reports mentioned adherence in their discussion. Conclusions and relevance: Using an adaptation of the World Health Organization framework for clinical adherence, this scoping review of randomized clinical trials identified key concepts as well as gaps in the way adherence is approached in design, conduct, and reporting of trials for skin self-examination and other self-management practices in people at high risk of melanoma. These findings may usefully guide future trials and clinical practice; evaluation of adherence strategies may be possible using a Study Within A Trial (SWAT) framework within host trials

    Can patient-led surveillance detect subsequent new primary or recurrent melanomas and reduce the need for routinely scheduled follow-up? A protocol for the MEL-SELF randomised controlled trial

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    This research project is funded by a National Health and Medical Research Council (NHMRC) Project grant (#1163054). The funder had no role in the design of the study and will have no role in the collection, analysis, and interpretation of the data; the writing of the report; or the decision to submit the report for publication. Funding Information: AEC is funded by a Career Development Fellowship from the National Health and Medical Research Council (NHMRC; 1147843). JFT is a recipient of an NHMRC Program Grant (1093017). RPMS is supported by Melanoma Institute Australia. RAS is supported by a NHMRC Program Grant and Practitioner Fellowship. For RAS, support from the from colleagues at Melanoma Institute Australia, Royal Prince Alfred Hospital and NSW Health Pathology is also gratefully acknowledged. RLM is supported with an NHMRC Investigator grant (1194703) and a University of Sydney Robinson Fellowship. HPS holds an NHMRC MRFF Next Generation Clinical Researchers Program Practitioner Fellowship (APP1137127). JH is supported by an NHMRC Early Career Fellowship (1112509). KB is supported by an NHMRC Investigator Grant (1174523) and a University of Sydney Research Accelerator (SOAR) Prize.Peer reviewedPublisher PD

    2006 Lowbush Blueberry Project Reports

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    The 2006 edition of the Lowbush Blueberry Project Reports was prepared for the Wild Blueberry Commission of Maine and the Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include: 1. Evaluation of Emerging Disinfection Technologies for Wild Blueberry Processing 2. Incorporation of wild blueberry puree into a soy-based burger and its effect on sensory and chemical properties of the broiled burgers 3. Infestation Detection using NIRS 4. Mechanism of Action through which Wild Blueberries affect Arterial Functional Properties in Normotensive and Spontaneously Hypertensive Rats 5. Practical Microbial Control Approach for Wild Blueberries and their Antimicrobial Property 6. Wild Blueberry Consumption and Risks for Cardiovascular Disease 7. Irrigation Water use in Wild Blueberry Production 8. Control Tactics for Blueberry Pest Insects & Program Base 9. Integrated Pest Management (IPM) Strategies 10. Biology and Ecology of Blueberry Insect Pests, 2006 11. Research on Wild Blueberry Diseases for 2006-2007 12. Effect of Soil pH on Nutrient Uptake 13. Effect of Manganese on Growth and Yield of Wild Blueberry 14. Effects of Summer Foliar Fertilization to Increase Branch Length and Flower Bud Formation in the Prune Year 15. Effects of Phosphite Foliar Fertilizers on disease control and fruit set of wild blueberry 16. Assessment of Hexazinone Alternatives for Weed Control in Wild Blueberries 17. Evaluation of Fall Applications of Tribenuron Methyl for Bunchberry Control in Wild Blueberries 18. Evaluation of spot treatments of Tribenuron Methyl, Ultim and Roundup for weed control in Wild Blueberries 19. Blueberry Extension Education Program 20. Cultural Weed Management Using p
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