Implementación de comunicación y algoritmos de control para UAV’S

Este artículo1 presenta el desarrollo de una plataforma de experimentación para poder ensayar estrategias de control con un vehículo aéreo no tripulado. Tras describir los diferentes componentes físicos que constituyen la plataforma, el artículo presenta la aplicación desarrollada bajo LabView para poder comunicar el helicóptero con la unidad fija. Finalmente se presentan algunos resultados experimentales que corroboran la funcionalidad de la aplicación, así como algunas mejoras que se están llevando a cabo sobre la misma

Implementación de comunicación y algoritmos de control para UAV’S

Este artículo1 presenta el desarrollo de una plataforma de experimentación para poder ensayar estrategias de control con un vehículo aéreo no tripulado. Tras describir los diferentes componentes físicos que constituyen la plataforma, el artículo presenta la aplicación desarrollada bajo LabView para poder comunicar el helicóptero con la unidad fija. Finalmente se presentan algunos resultados experimentales que corroboran la funcionalidad de la aplicación, así como algunas mejoras que se están llevando a cabo sobre la misma

Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes.

Hematopoietic stem and progenitor cells (HSPCs) and leukocytes circulate between the bone marrow (BM) and peripheral blood following circadian oscillations. Autonomic sympathetic noradrenergic signals have been shown to regulate HSPC and leukocyte trafficking, but the role of the cholinergic branch has remained unexplored. We have investigated the role of the cholinergic nervous system in the regulation of day/night traffic of HSPCs and leukocytes in mice. We show here that the autonomic cholinergic nervous system (including parasympathetic and sympathetic) dually regulates daily migration of HSPCs and leukocytes. At night, central parasympathetic cholinergic signals dampen sympathetic noradrenergic tone and decrease BM egress of HSPCs and leukocytes. However, during the daytime, derepressed sympathetic noradrenergic activity causes predominant BM egress of HSPCs and leukocytes via β3-adrenergic receptor. This egress is locally supported by light-triggered sympathetic cholinergic activity, which inhibits BM vascular cell adhesion and homing. In summary, central (parasympathetic) and local (sympathetic) cholinergic signals regulate day/night oscillations of circulating HSPCs and leukocytes. This study shows how both branches of the autonomic nervous system cooperate to orchestrate daily traffic of HSPCs and leukocytes

The correlation between urinary 5-hydroxyindoleacetic acid and sperm quality in infertile men and rotating shift workers

<p>Abstract</p> <p>Background</p> <p>Serotonin is a neurotransmitter that modulates a wide range of neuroendocrine functions. However, excessive circulating serotonin levels may induce harmful effects in the male reproductive system. The objective of this study was to evaluate whether the levels of urinary 5-hydroxyindoleacetic acid (5-HIIA), a major serotonin metabolite, correlate with different classical seminal parameters.</p> <p>Methods</p> <p>Human ejaculates were obtained from 40 men attending infertility counselling and rotating shift workers by masturbation after 4-5 days of abstinence. Urinary 5- HIIA concentration was quantified by using a commercial ELISA kit. Forward motility was assessed by a computer-aided semen analysis (CASA) system. Sperm concentration was determined using the haemocytometer method. Sperm morphology was evaluated after Diff-Quik staining, while sperm vitality was estimated after Eosin-Nigrosin vital staining.</p> <p>Results</p> <p>Our results show that urinary 5-HIIA levels obtained from a set of 20 volunteers negatively correlated with sperm concentration, forward motility, morphology normal range and sperm vitality. On the other hand, we checked the relationship between male infertility and urinary 5-HIIA levels in 20 night shift workers. Thus, urinary 5-HIIA levels obtained from 10 recently-proven fathers were significantly lower than those found in 10 infertile males. Additionally, samples from recent fathers exhibited higher sperm concentration, as well as better forward motility and normal morphology rate.</p> <p>Conclusions</p> <p>In the light of our findings, we concluded that high serotonin levels, indirectly measured as urinary 5-HIIA levels, appear to play a role as an infertility determinant in male subjects.</p

Reduced levels of intracellular calcium releasing in spermatozoa from asthenozoospermic patients

<p>Abstract</p> <p>Background</p> <p>Asthenozoospermia is one of the most common findings present in infertile males characterized by reduced or absent sperm motility, but its aetiology remains unknown in most cases. In addition, calcium is one of the most important ions regulating sperm motility. In this study we have investigated the progesterone-evoked intracellular calcium signal in ejaculated spermatozoa from men with normospermia or asthenozoospermia.</p> <p>Methods</p> <p>Human ejaculates were obtained from healthy volunteers and asthenospermic men by masturbation after 4–5 days of abstinence. For determination of cytosolic free calcium concentration, spermatozoa were loaded with the fluorescent ratiometric calcium indicator Fura-2.</p> <p>Results</p> <p>Treatment of spermatozoa from normospermic men with 20 micromolar progesterone plus 1 micromolar thapsigargin in a calcium free medium induced a typical transient increase in cytosolic free calcium concentration due to calcium release from internal stores. Similar results were obtained when spermatozoa were stimulated with progesterone alone. Subsequent addition of calcium to the external medium evoked a sustained elevation in cytosolic free calcium concentration indicative of capacitative calcium entry. However, when progesterone plus thapsigargin were administered to spermatozoa from patients with asthenozoospermia, calcium signal and subsequent calcium entry was much smaller compared to normospermic patients. As expected, pretreatment of normospermic spermatozoa with both the anti-progesterone receptor c262 antibody and with progesterone receptor antagonist RU-38486 decreased the calcium release induced by progesterone. Treatment of spermatozoa with cytochalasin D or jasplakinolide decreased the calcium entry evoked by depletion of internal calcium stores in normospermic patients, whereas these treatments proved to be ineffective at modifying the calcium entry in patients with asthenozoospermia.</p> <p>Conclusion</p> <p>Our results suggest that spermatozoa from asthenozoospermic patients present a reduced responsiveness to progesterone.</p

Biomecánica aplicada en el tejo como disciplina deportiva.

This paper presents the kinematic chains present in tejo, seen as a sport, which include some joints in certain identified biomechanical variables, such as athlete's center of gravity, angle of shooting, driving force and speed tejo launch, measurements made using traditional biomechanical research methods as the measurement technique of center of gravity according to Bernstein and Fischer, film techniques and dinamograficos methods, which are used in devices such as camcorders high filming, photo cells, cells load and strain gauges, devices associated with electronic circuits that enable high reliability of results, since it is the first study that is done at this level in this sport.Este artículo analiza el tejo como disciplina deportiva y algunas variables biomecánicas: centro de gravedad del deportista, ángulo de tiro, fuerza de impulso y velocidad de lanzamiento del tejo, mediciones hechas utilizando métodos de investigación biomecánicas tradicionales como la medición del centro de gravedad según Bernstein y Ficher,[1] técnicas cinematográficas y métodos dinamográficos, en los cuales se utilizaron dispositivos como cámaras de video, fotoceldas [2], celdas de carga y galgas extensiométricas [2], dispositivos asociados a circuitos electrónicos que permiten una alta fiabilidad de los resultados, ya que es el primer estudio que se hace a este nivel en esta práctica deportiva

Sistema robotizado para soldadura de circuitos impresos

En este artículo se da a conocer el desarrollo de un brazo robótico implementado con el fin de que sirva para soldar dispositivos electrónicos en los circuitos impresos, el sistema incluye un teclado que permite ingresar las coordenadas, los rangos de temperatura del cautín permitiendo obtener una soldadura adecuada para cada dispositivo y una pantalla LCD en la que se visualiza en tiempo real todos los datos que se ingresan, la automatización del este sistema se hizo usando el PIC 16F877A de la empresa Microchi

Efecto antileucémico de derivados cannabinoides: un nuevo grupo terapéutico en LMA

2 p.-3 fig.Los cannabinoides, componentes activos del cannabis, se emplean como tratamiento paliativo en pacientes con cáncer en virtud de su efecto antiemético y analgésico. Además, hay evidencias de que estos compuestos inhiben el crecimiento de algunas células tumorales en animales de laboratorio. Estos compuestos actúan uniéndose a receptores específicos. Los principales receptores son el CB1 (mayoritario en SNC) y CB2 (en tejido hematopoyético). El objetivo de este estudio fue confirmar el efecto terapéutico de derivados cannabinoides sintéticos específicos del receptor CB2 en LMA.Peer reviewe