Karagöz vardır ve yaşamıştır:Karagöz Kırklareli'nde doğmuş, oradan Bursa'ya gitmiştir, ismi Kambur Ahmet Efendi'dir

Taha Toros Arşivi, Dosya No: 176-Karagöz Sanatkarlarıİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033

CUMHURİYET VE HALKA GETİRDİKLERİ

Bu uzun tezde, Memduh Şevket Esendal’ın Ayaşlı ile Kiracıları adlı yapıtında, içeriği kapsayan Cumhuriyet’e geçiş döneminin getirdiği ahlaki değerlerdeki bazı değişimler, yapıttaki figürler aracılığıyla alt başlıklar halinde incelenmiştir. Anlatımın güçlenmesi için, ayrı ayrı figürlerin ön plana çıktığı bölümlerdeki diyaloglardan alıntılar yapılmıştır. Tezin oluşumu sırasında yapıtın olay örgüsünün bozulmamasına özen gösterilmiştir. Değinilen ahlaki değerler anlatılırken olayların akışının bozulmamasına gayret edilmiştir. Her alt başlık için öncelikle bir yargı belirtilmiş, ardından bu yargıyı destekleyen bir örnek verilmiştir

Hatıralar:Ahmet Haşim'i kaybettik

Taha Toros Arşivi, Dosya No: 78-Ahmet Haşimİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033

Milli mücadelede Hamdullah Suphi

Taha Toros Arşivi, Dosya No: 42-Hamdullah Suphi Tanrıöver. Not: Makale ekli dokümanın 65. sayfasında yer almaktadır

Haplotype frequencies of 17 Y-chromosomal short tandem repeat loci from the Cukurova region of Turkey

Aim To investigate the distribution of 17 Y-short tandem repeat (STR) loci in the population of the Cukurova region of Turkey. Methods In the period between 2009 and 2010, we investigated the distribution of 17 Y-STRs in a sample of 249 unrelated healthy men from the Cukurova region of Turkey. Genomic DNA was extracted with InstaGene matrix and Y-STRs were determined using the AmpFISTR Yfiler PCR amplification kit. Gene and haplotype diversity values were estimated using the Arlequin software. To compare our data to other populations, population pairwise genetic distances and associated probability values were calculated using the Y Chromosome Haplotype Reference Database Web site software. Results At 17 Y-STR loci we detected 148 alleles. The lowest gene diversity in this region was 0.51 for DYS391 and the highest 0.95 for DYS385a/b. Haplotype diversity was 0.9997 ± 0.0004. We compared our data with haplotype data of other Turkish populations and no significant differences were found, except with Ankara population (Φst = 0.025, P = 0.018). Comparisons were also made with the neighboring populations using analysis of molecular variance of the Y-STR loci genetic structure and our population was nearest to Lenkoran-Azerbaijani (Φst = 0.012, P = 0.068) and Iranian Ahvaz population (Φst = 0.007, P = 0.173), followed by Greek (Φst = 0.026, P = 0.000) and Russian (Φst = 0.048, P = 0.000) population. Other countries like Portugal, Spain, Italy, Egypt, Israel (Palestinian Authority Area), and Taiwan showed a high genetic distance from our population. Conclusion Our study showed that Y-STR polymorphisms were a powerful discrimination tool for routine forensic applications and could be used in genealogical investigations

Gene and protein expression of Transforming growth factor Β 2 gene during murine primary palatogenesis

The molecular mechanisms by which the primordia of the midface grow and fuse to form the primary palate are not well characterized. This is in spite of the fact that failure of growth and/or fusion of these facial primordia leads to the common human craniofacial birth defects, clefts of the lip with or without clefts of the palate. Members of the transforming growth factor Β ( Tgf Β) superfamily have been shown to play critical roles during craniofacial development. Specifically, the role of Tgf Β -3 in mediating the fusion of the embryonic secondary palatal shelves is well documented. In a screen for genes expressed during fusion of the murine midfacial processes, Tgf Β 2 was identified as a gene differentially expressed during fusion of the lateral and medial nasal processes. The objective of our study was to analyze the spatial and temporal expression of Tgf Β 2 during critical stages of midfacial morphogenesis at both the transcript and protein levels. We also compared the pattern of expression of Tgf Β 2 with that of Bmp4 , a gene shown previously to be involved in mediating the fusion process in the midface. Our results showed Tgf Β 2 expression in a very restrictive area of the epithelial layer along the borders of the midfacial primordia, in a pattern very similar to that of Bmp4 . The highly restrictive and spatial and temporal pattern of expression of Tgf Β 2 implicates its role in mediating the fusion of the midfacial processes, possibly through interacting with Bmp4 in the regulation of apoptosis and/or epithelial–mesenchymal transformation. A greater understanding of the role of this gene will clarify how the normal midface grows and the mechanisms behind cleft development.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72512/1/j.1432-0436.2005.00022.x.pd