Studies on the

The future Large Hadron electron Collider (LHeC) would allow collisions of an intense electron beam with protons or heavy ions at the High Luminosity-Large Hadron Collider (HL-LHC). Owing to a center of mass energy greater than a TeV and very high luminosity ($$\sim$$1 $$ab^{-1}$$), the LHeC would not only be a new generation collider for deep-inelastic scattering (DIS) but also an important facility for precision Higgs physics, complementary to pp and $$e^+e^-$$ colliders. Previously, it has been found that uncertainties of $$0.8\%$$ and $$7.4\%$$ can be achieved on the Higgs boson coupling strength to b- and c-quarks respectively. These results were obtained in the fast simulation frameworks for the LHeC detector. Focusing on the dominant Higgs boson decay channel, $$H\rightarrow bb$$, the present work aims to give a comparison of these results with a fully simulated detector. We present our results in this study using the publicly available ATLAS software infrastructure. Based on state-of-the art reconstruction algorithms, a novel analysis of the bb decay could be performed leading to an independent verification of the existing results to an exceptionally high precision

Constraining capability of Zγh production at the ILC

Higgs boson couplings with gauge bosons are probed through e−e+→Zγhe−e+→Zγh in an effective Lagrangian framework. For this study, the beam polarization facility at the ILC along with the typical center-of-mass energy of 500 GeV is considered. The reach of the ILC with an integrated luminosity of 300 fb−1−1 in the determination of CP-conserving parameters is obtained. Sensitivity of the probe of each of these couplings in the presence of other couplings is investigated. The most influential coupling parameters are c̄ W=−c̄ Bc̄W=−c̄B. Other parameters of significant effect are c̄ HWc̄HW and c̄ HBc̄HB. A detailed study of the various kinematic distributions represents possibilities to disentangle the effect of some of these couplings.by Sher Alam, Subhasish Behera, Satendra Kumar and Shibananda Saho

Prevalence of inhibitors in hemophilia patients and quantitative estimation of FVIII Inhibitors in hemophilia patients of Odisha

Objective:To know prevalence of factor VIII and IX inhibitors in Haemophilia patients and Quantitative estimation of factor VIII inhibitors in Haemophilia A patients using Bethesda Assay. Study Population: Hemophilia Patients receiving blood products and recombinant factor transfusion. Results: Total 54 cases were screened for factor deficiency and inhibitors. 42 old cases were screened and 12 new cases of Hemophilia A were screened for development of inhibitors.The mean age of patients in the study population was 14.38+8.12 years with age ranging from 9 months to 68 years. Prevalence of Hemophilia A was 92.6%, prevalence of Hemophilia B was 5.5%. There were 46% severe hemophilia A cases and 44% moderate hemophilia A cases and 10% mild hemophilia A cases. 40.74% cases had development of target joints with knee joint which was most commonly effected. Prevalence of inhibitors in Hemophilia A was 8%.It was 13% in severe hemophilia cases. 25% i.e. 1 patient was high responder with inhibitor level of 64 BU, other 3 inhibitor positive patients were low responders with inhibitor levels of 3BU, 3.2 BU and 4.4 BU. Conclusion: Severe hemophilia patients need frequent factor transfusions and are at higher risk of inhibitor development. Patients with low inhibitor levels i.e.<10BU need high dose of recombinant factor VIII. Patients with high inhibitor levels >10 BU may require Recombinant factor VII with or without immune tolerance therapy. So inhibitor screening and Bethesda assay is needed at least once in every six months for prompt treatment

Preparedness among dental professionals towards COVID-19 in India

Introduction: novel corona virus infection has become a public health crisis leading the world to a standstill including dentistry. However, since the dental services cannot be stopped for a long period it is important that dentist be fully prepared before resuming their services. Therefore, the current study was carried out for evaluating knowledge, attitude and practices (KAP) along with perceived barriers to practice dentistry during pandemic. Methods: this cross-sectional study was conducted through an online survey questionnaire on dentists of India. Dentists were enquired for demographics, KAP and perceived barriers regarding practicing dentistry during pandemic. The knowledge was assessed based on 16 items in true or false or multiple choice questions format getting score of 1 or 0. The attitude and practices by 8 items each, on 5-point Likert scale and 4 items perceived barriers were enquired. The differences between the median scores among demographic variables were determined by applying student's t-test and keeping level of significance at below 0.05. Results: out of 500 dentists who were approached through email, a total of 296 dentists returned the questionnaire (response rate, 59.2%) among which 22 questionnaires were incomplete and thus excluded making 274 as final study participants. Overall poor median scores of knowledge and practices were obtained whereas for attitude total median score was good. Median practice scores were significantly higher among female respondents (20(6)). Median knowledge and practice scores were significantly better in study participants with age <40 years (6(4) and 19(5), respectively). Conclusion: with the recent claims of authorities that virus is going to stay in world for quite some time it is essential that dentists must be fully prepared before resuming their services and must attain proper awareness to limit the disease spread

Effect of different level of concentrate supplementation on the periparturient growth performance of Ganjam goat in extensive system

Aim: The present study was carried out to evaluate the impact of concentrate supplementation to the pregnant Ganjam goats on their growth performance in periparturient period. Materials and Methods: A total of 45 pregnant Ganjam does of similar body weight, age and parity were divided into three treatment groups with 15 does in each. T1 : normal browsing at range system, T2 : normal browsing with concentrate supplementation @ 200g/day, T3 : normal browsing with concentrate supplementation @ 300g/day for 60 days before expected date of kidding. Observations regarding various growth performances were made following standard procedures. Results: Average daily concentrate feed intake for T2 was 160 g and 225 g for T3 . For the does in T1 , the body weights ranged from 34.59 ± 0.75 kg (at the beginning) to 38.29 ± 0.75 kg (after 60 days of supplementation) while for those in T2 it increased from 33.91 ± 0.70 kg to 38.71 ± 0.64 kg and for T3 itranged from 34.05 ± 0.64 to 39.55 ± 0.62 kg. The cumulative live weight gain during the period 0-60 days varied significantly among the different treatments with the lowest value in T1 (3.71 ± 0.27 kg) to highest value in T3 (5.49 ± 0.22 kg) although the initial body weights were same. The cumulative body weight gain during 0- 90 days postpartum was significantly higher in T1 (3.13 ± 0.46 kg) compared to T3 (2.10 ± 0.19 kg). Significant difference in average daily gain during prepartum period was found in all groups as 61.78 ± 4.47, 79.89 ± 2.20, 91.56 ± 3.71 for T1, T2 and T3 respectively. The average daily gain of the does during post partum period was 23.33 g (T3 ), 24.30 g (T2 ) and 34.81 g (T1 ) perdoe indicating a statistically significant difference among the treatments. Conclusion: It is concluded that on supplementation of concentrate between 160 to 225 g improved both prepartum and postpartum body condition of Ganjam goats. [Vet World 2013; 6(7.000): 428-432

International Large Detector: Interim Design Report

The ILD detector is proposed for an electron-positron collider with collision centre-of-mass energies from 90~\GeV~to about 1~\TeV. It has been developed over the last 10 years by an international team of scientists with the goal to design and eventually propose a fully integrated detector, primarily for the International Linear Collider, ILC. In this report the fundamental ideas and concepts behind the ILD detector are discussed and the technologies needed for the realisation of the detector are reviewed. The document starts with a short review of the science goals of the ILC, and how the goals can be achieved today with the detector technologies at hand. After a discussion of the ILC and the environment in which the experiment will take place, the detector is described in more detail, including the status of the development of the technologies foreseen for each subdetector. The integration of the different sub-systems into an integrated detector is discussed, as is the interface between the detector and the collider. This is followed by a concise summary of the benchmarking which has been performed in order to find an optimal balance between performance and cost. To the end the costing methodology used by ILD is presented, and an updated cost estimate for the detector is presented. The report closes with a summary of the current status and of planned future actions

The ILD detector at the ILC

The International Large Detector, ILD, is a detector concept which has been developed for the electron-positron collider ILC. The detector has been optimized for precision physics in a range of energies between 90 GeV and 1 TeV. ILD features a high precision, large volume combined silicon and gaseous tracking system, together with a high granularity calorimeter, all inside a 3.5 T solenoidal magnetic field. The paradigm of particle flow has been the guiding principle of the design of ILD. In this document the required performance of the detector, the proposed implementation and the readiness of the different technologies needed for the implementation are discussed. This is done in the framework of the ILC collider proposal, now under consideration in Japan, and includes site specific aspects needed to build and operate the detector at the proposed ILC site in Japan