De Bloemmolens van Diksmuide (prov. West-Vlaanderen). Het industrieel erfgoed van een grootmaalderij

The Flour Mills of Diksmuide were originally a sugar refinery, built in 1836 by the Van Hille brothers on the border of the IJzer in Diksmuide. In the years 1830 the young Belgian government provided fiscal stimulation for the cultivation of sugar beet to the detriment of the import of sugarcane in bulk. After a period of disuse in the years 1880, the mill was bought in 1891 by the miller Eugène Devos-Quatannes bought in 1891 in order to start up a steam-powered flour and oil mill. During the First World War the steam mill, located twenty metres from the first Belgian-French line, was irrecoverably transformed by the Germans into a blockhouse. After the war the building became a War Memorial. Between 1923-1925 a new flour and oil mill was built near the confluence of the IJzer and the Handzame canal by Eugène Devos and the Sociéte Anonyme Minoteries et Huileries de Dixmude à Bruxelles. In 1932 the Flour and Oil Mills of Diksmuide were bought out by the company Florizoone & Cloet Brothers of Veurne. Onder the management of the Sociéte Anonyme de Minoteries et Huileries de Dixmude, which later became the N.V. Bloemmolens en Olieslagerijen van Diksmuide, a prosperous period began for the flour mill. The oil mill never went into production. After building a new flour mill in the industrial estate Kleine Dries in Diksmuide the outdated Flour and Oil Mills were demolished in 1995. The two factory towers with the stockroom, the screenroom and the mill still stand as industrial monuments

Antioxidant Enzymes as New Biomarkers for Prediction of Tumor Progression in Breast Cancer

International audienc

Teacher design teams as a strategy for professional development : the role of the facilitator

The goal of the current study was to explore the role and importance of the facilitator in Teacher Design Teams. The study took place in the context of a pre-service teacher education institution in Belgium, where teacher design teams were set up to facilitate the professional development of teacher educators. The findings from focus group discussions with team members and semi-structured interviews with facilitators confirm that the perceived importance of a facilitator depends on several factors, such as team characteristics and the design phase. Moreover, we found that a facilitator can fulfil three roles in a dynamic way: 1) providing logistic support, 2) scaffolding the design process and 3) monitoring the design process. The discussion centers on how these results can be used to support facilitators for successful Teacher Design Teams

Of an oste as they drie their hoppes upon at Poppering. Een typologische benadering van de hopast in Vlaanderen

Tot voor enkele jaren genoten hopasten in Vlaanderen vanuit de erfgoedsector weinig aandacht. Nochtans waren ze vooral in de streken rond Poperinge, Aalst en Asse/Ternat talrijk aanwezig in ons rurale landschap. Met de gedeeltelijke teloorgang en mechanisering van de hopteelt verloren deze droogovens echter hun functie én bestaansrecht. Om het algemeen verdwijnen van dit rurale erfgoed tegen te gaan inventariseerde de erfgoedvereniging De Keteniers in de Poperingse hopstreek het nog aanwezige hoperfgoed. De beschikbaarheid van deze inventaris nodigde dan ook uit om de typologische ontwikkeling van de hopasten in Vlaanderen verder te onderzoeken en aldus een motiveringskader aan te reiken voor hun bescherming en beheer

Conditions for the successful implementation of teacher educator design teams for ICT integration : a Delphi study

Teacher educators often struggle to model effective integration of technology. Several studies suggest that the involvement of teacher educators in collaborative design is effective in developing the competences necessary for integrating information and communication technology (ICT) in teaching. In a teacher educator design team (TeDT), two or more teacher educators (re-)design curriculum materials together. For the successful implementation of TeDTs, conditions at both team and institutional levels have to be taken into account. However, there is little consensus among stakeholders about which of these conditions are of highest priority. Most studies present priority or critical conditions from the viewpoint of just one group (e.g., school leaders). A Delphi study was set up aiming at synthesising the knowledge and views of various stakeholders about the conditions for the successful implementation of TeDTs for ICT integration. Consensus about the importance of ten conditions was reached in the entire sample after three rounds. These conditions include a long-term vision, trust, ownership, time and supportive institutional policies

Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family

This is an open access article distributed under the Creative Commons Attribution License.-- et al.In metazoans, proteins of the arrestin family are key players of G-protein-coupled receptors (GPCRS) signaling and trafficking. Following stimulation, activated receptors are phosphorylated, thus allowing the binding of arrestins and hence an >arrest> of receptor signaling. Arrestins act by uncoupling receptors from G proteins and contribute to the recruitment of endocytic proteins, such as clathrin, to direct receptor trafficking into the endocytic pathway. Arrestins also serve as adaptor proteins by promoting the recruitment of ubiquitin ligases and participate in the agonist-induced ubiquitylation of receptors, known to have impact on their subcellular localization and stability. Recently, the arrestin family has expanded following the discovery of arrestin-related proteins in other eukaryotes such as yeasts or fungi. Surprisingly, most of these proteins are also involved in the ubiquitylation and endocytosis of plasma membrane proteins, thus suggesting that the role of arrestins as ubiquitin ligase adaptors is at the core of these proteins' functions. Importantly, arrestins are themselves ubiquitylated, and this modification is crucial for their function. In this paper, we discuss recent data on the intricate connections between arrestins and the ubiquitin pathway in the control of endocytosis.This work was supported by the CNRS and by a Grant from the Fondation ARC pour la recherche sur le cancer (SFI20101201844) to S. Léon, and by a Grant from the Spanish CICYT (BFU2008-02005) to O. Vincent. M. Becuwe and A. Herrador are recipients of Ph.D. fellowships from the French Ministère de l’Enseignement Supérieur et de la Recherche and from CSIC-JAE, respectively.Peer Reviewe