Senior Recital: Mat Becker, Trombone; Nancy Pounds, Piano; April 25, 2010

Kemp Recital HallApril 25, 2010SundayNoo

The Leisure Industry - A Perspective

The purpose of this study was to identify major issues facing the leisure industry in the 80\u27s. The important element isolated to improving products, services, programs, and/or facilities is quality

¹⁵N Nuclear Magnetic Resonance Studies of the Liver Alcohol Dehydrogenase-NAD⁺-Pyrazole Complex

The structures of the liver alcohol dehydrogenase (LADH)-NAD+-pyrazole and LADH-NAD+-4-ethylpyrazole complexes were investigated by 15N nuclear magnetic resonance (NMR) spectroscopy. 15N chemical shifts were obtained for 15N-labeled inhibitors and 15N-labeled coenzyme bound in the enzyme ternary complexes. The structures of the two inhibitor complexes were found to be very similar. 15N chemical shifts of various pyrazole derivatives were determined. 15N NMR studies of model pyrazole derivative-zinc chloride complexes were carried out to determine the effect of zinc complexation on the pyrazole N2 chemical shift. The N1 nicotinarnide resonance of the coenzyme of the LADH-NAD+-pyrazole complex was 96 ppm upfield from that of NAD+ in solution and only 13 ppm downfield from that of NADH in solution, demonstrating formation of a derivative of dihydronicotinamide. The 15N chemical shift of the pyrazole N1 of the ternary complex when compared to other pyrazole derivatives indicated bond formation between pyrazole N1 and the nicotinarnide ring of the coenzyme. The 15N shift of the pyrazole N1 of the model pyrazole-NAD+ adduct, N-benzyl-1,4-dihydro-4-pyrazolylnicotinarnide, was 5.8 ppm downfield from that of N1 of the enzyme ternary complex. The 15N chemical shift of the pyrazole N2 of the ternary complex compared to pyrazole derivatives in solution was shielded by more than 40 ppm, demonstrating direct complexation of N2 to the active-site zinc. The results of model zinc complex studies indicated 60-100% inner-sphere coordination of the pyrazole N2 to the active-site zinc in the ternary complex.</p

Family food patterns and dietary change in an intervention study : the Family Heart Study

Division of labor in household food preparation tasks is of interest in dietary intervention projects. Randomly selected families were recruited to participate in a 5-year family-based study. A small group format that emphasized family involvement was used to promote change from the American diet (40% fat, 500 mg cholesterol P/S = .05) to the Alternative diet (20% fat, 100 mg cholesterol, P/S = 1.0). The change of division of labor in the households was evaluated from baseline to 60 months. A subsample of 109 male-female couples who were not divorced, pregnant or ill, responded to a questionnaire regarding who does the cooking, shopping and deciding what the family will eat. Plasma lipids and dietary intake were assessed at baseline and at 60 months. At baseline, the majority of men and women indicated that the wives did most of the cooking, deciding and shopping, although both women and men indicated that they did more of the task than their spouse said they did. The overall distribution of labor in cooking and deciding did not significantly change after 5 years of dietary intervention at the family level; however, there was a trend towards increased participation by the men in these tasks. Men's participation in shopping, however, significantly increased. The couples were grouped according the husbands' reported increase or decrease in involvement in these tasks, and diet and lipid changes were evaluated. Increased involvement in household food preparation tasks did not lead to significantly greater dietary change except for consumption of polyunsaturated fat. The wives of men who increased their shopping reported an increase in total fat and saturated fat when compared to changes seen in the other wives. Taken as a group, both husbands and wives decreased their reported fat, cholesterol and saturated fat consumption and increased their reported carbohydrate intake in a manner similar to that suggested in Phase 1 of the Alternative diet. Plasma lipids remained stable in both men and women. Household food-related task performance does not profoundly change when couples participate in a family-based intervention project, and the small changes seen do not have an effect on the outcome variables

Psychosocial dwarfism: Detection, evaluation and management

Our experience with 35 children with psychosocial dwarfism (PSD) over five years Is reviewed. Diagnosis and management are difficult. A multidisciplinary approach to the evaluation allows for maximal observation of family psychodynamics and Intervention. Foster placement remains the Intervention of choice in children over four years of age.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/23737/1/0000709.pd

Community Conflicts over Intensive Livestock Operations: How and Why Do Such Conflicts Escalate?

Why do community groups and individuals oppose establishment of intensive scale livestock operations in communities? Why have established forms of economic activity become the pariah of rural communities across the nation? In December 1997, the Pennsylvania Senate passed Resolution 91. This article addresses the results of a research project funded by the state Department of Agriculture in response to Senate Resolution 91, directing the Secretary of Agriculture to develop a model of community dispute resolution to address community conflicts involving intensive livestock operations ( ILOs ). Specifically this article addresses project findings detailing why conflicts over ILOs arise and how they escalate

Livestock abundance predicts vampire bat demography, immune profiles, and bacterial infection risk

Human activities create novel food resources that can alter wildlife–pathogen interactions. If resources amplify or dampen, pathogen transmission probably depends on both host ecology and pathogen biology, but studies that measure responses to provisioning across both scales are rare. We tested these relationships with a 4-year study of 369 common vampire bats across 10 sites in Peru and Belize that differ in the abundance of livestock, an important anthropogenic food source. We quantified innate and adaptive immunity from bats and assessed infection with two common bacteria. We predicted that abundant livestock could reduce starvation and foraging effort, allowing for greater investments in immunity. Bats from high-livestock sites had higher microbicidal activity and proportions of neutrophils but lower immunoglobulin G and proportions of lymphocytes, suggesting more investment in innate relative to adaptive immunity and either greater chronic stress or pathogen exposure. This relationship was most pronounced in reproductive bats, which were also more common in high-livestock sites, suggesting feedbacks between demographic correlates of provisioning and immunity. Infection with both Bartonella and haemoplasmas were correlated with similar immune profiles, and both pathogens tended to be less prevalent in high-livestock sites, although effects were weaker for haemoplasmas. These differing responses to provisioning might therefore reflect distinct transmission processes. Predicting how provisioning alters host–pathogen interactions requires considering how both within-host processes and transmission modes respond to resource shifts