607 research outputs found
What is a smart building?
Purpose
Within the building sector a lack of clarity in terminology does not help designers, clients or researchers. Non-domestic buildings have shown rapid increases in the use of advanced technology and control systems with varying drivers, many of which are labelled as intelligent. The term smart has been used interchangeably with intelligent without any clear distinction between the two. If the term Smart Buildings represented a separate, more advanced grouping, it would provide an opportunity to focus the future progress of non-domestic building development. The paper aims to discuss these issues.
Design/methodology/approach
Drawing upon academic and industrial literature and experience, this paper reviews the scope of Intelligent Buildings and the current available definitions of Smart Buildings to form a clear definition of both smart and Intelligent Buildings.
Findings
These definitions define the border between the intelligent and the (more advanced) Smart Building. The upper bound of the Smart Building is defined by (the future development of) the predictive building.
Originality/value
This work provides a clear focus which will allow the progression of the non-domestic building sector by providing guidance and aspiration, as well as providing a platform upon which a large amount of technical work can be based
An integrated approach to modelling the fluid-structure interaction of a collapsible tube
The well known collapsible tube experiment was conducted to obtain flow, pressure and materials property data for steady state conditions. These were then used as the boundary conditions for a fully coupled fluid-structure interaction (FSI) model using a propriety computer code, LS-DYNA. The shape profiles for the tube were also recorded. In order to obtain similar collapse modes to the experiment, it was necessary to model the tube flat, and then inflate it into a circular profile, leaving residual stresses in the walls. The profile shape then agreed well with the experimental ones. Two departures from the physical properties were required to reduce computer time to an acceptable level. One of these was the lowering of the speed of sound by two orders of magnitude which, due to the low velocities involved, still left the mach number below 0.2. The other was to increase the thickness of the tube to prevent the numerical collapse of elements. A compensation for this was made by lowering the Young's modulus for the tube material. Overall the results are qualitatively good. They give an indication of the power of the current FSI algorithms and the need to combine experiment and computer models in order to maximise the information that can be extracted both in terms of quantity and quality
Vanishing spin alignment : experimental indication of triaxial nuclear molecule
Fragment-fragment- coincidences have been measured for at an energy corresponding to the population of a conjectured
resonance in Ni. Fragment angular distributions as well as -ray
angular correlations indicate that the spin orientations of the outgoing
fragments are perpendicular to the orbital angular momentum. This differs from
the and the resonances, and
suggests two oblate nuclei interacting in an equator-to-equator
molecular configuration.Comment: 14 pages standard REVTeX file, 3 ps Figures -- Accepted for
publication in Physical Review C (Rapid Communication
Relativistic graphene ratchet on semidisk Galton board
Using extensive Monte Carlo simulations we study numerically and analytically
a photogalvanic effect, or ratchet, of directed electron transport induced by a
microwave radiation on a semidisk Galton board of antidots in graphene. A
comparison between usual two-dimensional electron gas (2DEG) and electrons in
graphene shows that ratchet currents are comparable at very low temperatures.
However, a large mean free path in graphene should allow to have a strong
ratchet transport at room temperatures. Also in graphene the ratchet transport
emerges even for unpolarized radiation. These properties open promising
possibilities for room temperature graphene based sensitive photogalvanic
detectors of microwave and terahertz radiation.Comment: 4 pages, 4 figures. Research done at Quantware
http://www.quantware.ups-tlse.fr/. More detailed analysis is give
Ten years of the Hunter Outcome Survey (HOS) : insights, achievements, and lessons learned from a global patient registry
Mucopolysaccharidosis type II (MPS II; Hunter syndrome; OMIM 309900) is a rare lysosomal storage disease with progressive multisystem manifestations caused by deficient activity of the enzyme iduronate-2-sulfatase. Diseasespecific treatment is available in the form of enzyme replacement therapy with intravenous idursulfase (Elaprase®, Shire). Since 2005, the Hunter Outcome Survey (HOS) has collected real-world, long-term data on the safety and effectiveness of this therapy, as well as the natural history of MPS II. Individuals with a confirmed diagnosis of MPS II who are untreated or who are receiving/have received treatment with idursulfase or bone marrow transplant can be enrolled in HOS. A broad range of disease- and treatment-related information is captured in the registry and, over the past decade, data from more than 1000 patients from 124 clinics in 29 countries have been collected. Evidence generated from HOS has helped to improve our understanding of disease progression in both treated and untreated patients and has extended findings from the formal clinical trials of idursulfase. As a long-term, global, observational registry, various challenges relating to data collection, entry, and analysis have been encountered. These have resulted in changes to the HOS database platform, and novel approaches to maximize the value of the information collected will also be needed in the future. The continued evolution of the registry should help to ensure that HOS provides further insights into the burden of the disease and patient care and management in the coming years
Charge and spin dynamics in the one-dimensional and models
The impact of the spin-flip terms on the (static and dynamic) charge and spin
correlations in the Luttinger-liquid ground state of the 1D model is
assessed by comparison with the same quantities in the 1D model, where
spin-flip terms are absent. We employ the recursion method combined with a
weak-coupling or a strong-coupling continued-fraction analysis. At
we use the Pfaffian representation of dynamic spin correlations. The changing
nature of the dynamically relevant charge and spin excitations on approach of
the transition to phase separation is investigated in detail. The
charge excitations (but not the spin excitations) at the transition have a
single-mode nature, whereas charge and spin excitations have a complicated
structure in the model. In the model, phase separation is
accompanied by N\'eel long-range order, caused by the condensation of electron
clusters with an already existing alternating up-down spin configuration
(topological long-range order). In the model, by contrast, the spin-flip
processes in the exchange coupling are responsible for continued strong spin
fluctuations (dominated by 2-spinon excitations) in the phase-separated state.Comment: 11 pages (RevTex). 14 Figures available from author
Atomic diffraction from nanostructured optical potentials
We develop a versatile theoretical approach to the study of cold-atom
diffractive scattering from light-field gratings by combining calculations of
the optical near-field, generated by evanescent waves close to the surface of
periodic nanostructured arrays, together with advanced atom wavepacket
propagation on this optical potential.Comment: 8 figures, 10 pages, submitted to Phys. Rev.
Molecular mechanisms linking high body mass index to breast cancer etiology in post-menopausal breast tumor and tumor-adjacent tissues
Purpose: In post-menopausal women, high body mass index (BMI) is an established breast cancer risk factor and is associated with worse breast cancer prognosis. We assessed the associations between BMI and gene expression of both breast tumor and adjacent tissue in estrogen receptor-positive (ER+) and estrogen receptor-negative (ER−) diseases to help elucidate the mechanisms linking obesity with breast cancer biology in 519 post-menopausal women from the Nurses’ Health Study (NHS) and NHSII. Methods: Differential gene expression was analyzed separately in ER+ and ER− disease both comparing overweight (BMI ≥ 25 to < 30) or obese (BMI ≥ 30) women to women with normal BMI (BMI< 25), and per 5 kg/m 2 increase in BMI. Analyses controlled for age and year of diagnosis, physical activity, alcohol consumption, and hormone therapy use. Gene set enrichment analyses were performed and validated among a subset of post-menopausal cases in The Cancer Genome Atlas (for tumor) and Polish Breast Cancer Study (for tumor-adjacent). Results: No gene was differentially expressed by BMI (FDR < 0.05). BMI was significantly associated with increased cellular proliferation pathways, particularly in ER+ tumors, and increased inflammation pathways in ER− tumor and ER− tumor-adjacent tissues (FDR < 0.05). High BMI was associated with upregulation of genes involved in epithelial-mesenchymal transition in ER+ tumor-adjacent tissues. Conclusions: This study provides insights into molecular mechanisms of BMI influencing post-menopausal breast cancer biology. Tumor and tumor-adjacent tissues provide independent information about potential mechanisms
Multiwavelength studies of MHD waves in the solar chromosphere: An overview of recent results
The chromosphere is a thin layer of the solar atmosphere that bridges the
relatively cool photosphere and the intensely heated transition region and
corona. Compressible and incompressible waves propagating through the
chromosphere can supply significant amounts of energy to the interface region
and corona. In recent years an abundance of high-resolution observations from
state-of-the-art facilities have provided new and exciting ways of
disentangling the characteristics of oscillatory phenomena propagating through
the dynamic chromosphere. Coupled with rapid advancements in
magnetohydrodynamic wave theory, we are now in an ideal position to thoroughly
investigate the role waves play in supplying energy to sustain chromospheric
and coronal heating. Here, we review the recent progress made in
characterising, categorising and interpreting oscillations manifesting in the
solar chromosphere, with an impetus placed on their intrinsic energetics.Comment: 48 pages, 25 figures, accepted into Space Science Review
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