Hálózatba csatolt social network számláló egység

Modern világunkban az információ gyors áramlása elengedhetetlen a vállalatok számára. Egyre több embernek jelent sokat a népszerűség. Számos cég és vállalat indított web lapot vagy csatornát a közösségi oldalakon, ismeretterjesztő, oktatási, kutatási vagy jobb kommunikáció céljából. A fentiek figyelembe vétele mellett került megtervezésre, egy hálózatba csatolt „Social Network” számláló, melynek révén aktuális értéket kaphatunk az éppen feliratkozott követők számáról. Az eszköz automatikusan frissíti az aktuális követők, feliratkozók számát, így mindig a friss adatokat mutatja

Application of attenuated total reflectance Fourier transform infrared spectroscopy in the mineralogical study of a landslide area, Hungary

This study demonstrates that the unpolarized attenuated total reflectance Fourier transform infrared spectroscopy (ATR FTIR) is a practical and quick tool to distinguish different types of sediments in landslide-affected areas, and potentially other types of physical environments too. Identification and quantification of minerals by ATR FTIR is implemented on a set of powdered natural sediments from a loess landslide (Kulcs, Hungary). A protocol including sample preparation, analytical conditions and evaluation of sediment ATR spectra is outlined in order to identify and estimate major minerals in sediments. The comparison of the defined FTIR parameters against qualitative and quantitative results of X-ray diffraction and thermal analysis was used to validate the use of ATR FTIR spectroscopy for the considered sediments. The infrared band areas and their ratios (water/carbonates; silicates/carbonates; kaolinite) appear to be the most sensitive parameters to identify strongly weathered sediments such as paleosols and red clays which most likely facilitate sliding and could form sliding zones. The effect of grain size and orientation of anisotropic minerals on the wave number and intensity of some major absorption bands is also discussed

Szorongás, depresszió, egészségkontrollhit és az egészség-magatartással való kapcsolatuk ischaemiás szívbetegek körében

Absztrakt Bevezetés: Az ischaemiás szívbetegség vezető haláloknak számít hazánkban. Kialakulásában és a betegség prognózisában is kiemelkedő szerepet játszanak a mentális és az életmódbeli tényezők. Célkitűzés: Ischaemiás szívbetegek körében a szorongás, a depresszió és az egészséggel kapcsolatos kontrollérzés, valamint az egészség-magatartások összefüggéseinek elemzése. Módszer: Keresztmetszeti vizsgálatban 116 kardiológiai rehabilitációs osztályon fekvő beteg vett részt (56,9% férfi, átlagéletkor: 57,65±8,22 év). Eredmények: A betegek 30,9%-a számolt be megemelkedett szorongásról és 21,9%-a depressziós hangulatról. Az egészségkontrollhit tekintetében e betegek körében a más személyek befolyásában való hit volt a legerősebb. A kevésbé szorongó és kevesebb depressziós tünetet mutató betegek gyakrabban figyeltek oda az egészséges táplálkozásra és a testmozgásra. Az erősebb belső kontrollhittel rendelkezők nagyobb eséllyel végeztek testmozgást, a társas külső kontroll skálán magas értéket mutatók pedig nagyobb valószínűséggel keresték fel orvosukat, ha betegségre gyanakodtak. Következtetések: A kardiológiai rehabilitáció során fontos a szívbetegséggel kapcsolatos mentális tényezők átfogó vizsgálata és szükség esetén adekvát pszichológiai intervenciók alkalmazása. Orv. Hetil., 2015, 156(20), 813–822

Increased nociceptin/orphanin FQ plasma levels in hepatocellular carcinoma

AIM: The heptadecapeptide nociceptin alias orphanin FQ is the endogenous agonist of opioid receptor-like1 receptor. It is involved in modulation of pain and cognition. High blood level was reported in patients with acute and chronic pain, and in Wilson disease. An accidental observation led us to investigate nociceptin in hepatocellular carcinoma. METHODS: Plasma nociceptin level was measured by radioimmunoassay, aprotinin was used as protease inhibitor. Hepatocellular carcinoma was diagnosed by laboratory, ultrasound, other imaging, and confirmed by fine needle biopsy. Results were compared to healthy controls and patients with other chronic liver diseases. RESULTS: Although nociceptin levels were elevated in patients with Wilson disease (14.0 +/- 2.7 pg/mL, n = 26), primary biliary cirrhosis (12.1 +/- 3.2 pg/mL, n = 21) and liver cirrhosis (12.8 +/- 4.0 pg/mL, n = 15) compared to the healthy controls (9.2 +/- 1.8 pg/mL, n = 29, P < 0.001 for each), in patients with hepatocellular carcinoma a ten-fold increase was found (105.9 &PLUSMN; 14.4 pg/mL, n = 29, P < 0.0001). High plasma levels were found in each hepatocellular carcinoma patient including those with normal alpha fetoprotein and those with pain (104.9 +/- 14.9 pg/mL, n = 12) and without (107.7 +/- 14.5 pg/mL, n = 6). CONCLUSION: A very high nociceptin plasma level seems to be an indicator for hepatocellular carcinoma. Further research is needed to clarify the mechanism and clinical significance of this novel finding

Comparative investigation of 11 Achillea collina Becker accessions concerning phenological, morphological, productional features and active agent content

Eleven Achillea collina Becker accessions of different origin were tested in open field plots during three years for their phenological, morphological, productional features and active material content in Budapest, Hungary. Among the tested plant materials European selected cultivars, Hungarian cultivated stocks and populations from wild growing habitats were investigated. Concerning flowering time, two types (early and late) were distinguished. Flowering time of the less abundant late type, represented by Hungarian variety ‘Azulenka’ and ‘Gb22’, started approximately 2 weeks later than that of the early flowering type. Plant height and length of flowering horizon varied only slightly among taxa, and increased after the first year of cultivation. The proportion of useful plant organs in the drug was stable. Biomass and drug production of the investigated genotypes was variable, late flowering types providing higher yields. Essential oil, proazulene, total phenolic and flavonoid content varied on a large scale among accessions and years.Results demonstrate the high intraspecific variability of A. collina and also the role of valuable genotypes in drug production. Selected cultivars may provide stable and good yields and drug quality under particular environmental conditions, while genotypes of wild origin may be valuable sources of future breeding programs

Rising plasma nociceptin level during development of HCC: A case report

AIM: Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC), relatively few reports are available on HCC in primary biliary cirrhosis. High plasma nociceptin (N/OFQ) level has been shown in Wilson disease and in patients with acute and chronic pain. METHODS: We report a follow-up case of HCC, which developed in a patient with primary biliary cirrhosis. The tumor appeared 18 years after the diagnosis of PBC and led to death within two years. Alfa fetoprotein and serum nociceptin levels were monitored before and during the development of HCC. Nociceptin content was also measured in the tumor tissue. RESULTS: The importance and the curiosity of the presented case was the novel finding of the progressive elevation of plasma nociceptin level up to 17-fold (172 pg/mL) above the baseline (9.2 +/- 1.8 pg/mL) parallel with the elevation of alpha fetoprotein (from 13 ng/mL up to 3 480 ng/mL) during tumor development. Nociceptin content was more than 15-fold higher in the neoplastic tissue (0.16 pg/mg) than that in the tumor-free liver tissue samples (0.01 pg/mg) taken during the autopsy. CONCLUSION: Results are in concordance with our previous observation that a very high plasma nociceptin level may be considered as an indicator for hepatocellular carcinoma