Wastes of metallurgical production as a new mineral and raw resource

Обсуждается проблема утилизации и переработки отходов металлургического производства как альтернативного источника сырья для профильных предприятий. Предлагается объединение алюминиевых заводов в единый кластер для рециклинга эксплуатационных техногенных отходов.The problem of processing of metallurgical wastes as alternative mineral resource for special entertainments is discussed. In this paper are proposed of aluminium smelter company in united cluster for recycling processing wastes

Myeloid-Derived Suppressor Cells in Tumors: From Mechanisms to Antigen Specificity and Microenvironmental Regulation

Among the various immunological and non-immunological tumor-promoting activities of myeloid-derived suppressor cells (MDSCs), their immunosuppressive capacity remains a key hallmark. Effort in the past decade has provided us with a clearer view of the suppressive nature of MDSCs. More suppressive pathways have been identified, and their recognized targets have been expanded from T cells and natural killer (NK) cells to other immune cells. These novel mechanisms and targets afford MDSCs versatility in suppressing both innate and adaptive immunity. On the other hand, a better understanding of the regulation of their development and function has been unveiled. This intricate regulatory network, consisting of tumor cells, stromal cells, soluble mediators, and hostile physical conditions, reveals bi-directional crosstalk between MDSCs and the tumor microenvironment. In this article, we will review available information on how MDSCs exert their immunosuppressive function and how they are regulated in the tumor milieu. As MDSCs are a well-established obstacle to anti-tumor immunity, new insights in the potential synergistic combination of MDSC-targeted therapy and immunotherapy will be discussed

Thermal Stability of Hafnium Diboride Films, Obtained on Substrates of Steel 12X18H9T and Cutting Plate T15K6

Investigation results of the influence of high-temperature annealing in the air environment on the phase structure and structure of hafnium diboride films, received on substrates from steel 12Х18Н9Т and cutting plate Т15К6 are presented. It is shown that in the course of annealing on a surface of HfВ2 film the oxide layer of HfО2, with monoclinic structure is formed. Thus, annealing temperature increase from 600 to 1000 С leads to increase in thickness of an oxide layer from 100 to 600 nanometers and to formation of a multilayered covering of HfB2 - HfO2. On substrates of steel 12Х18Н9Т the coating is destructed at the temperature higher on 800 C than for Т15К6. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3492

Detrifluoroacetylation of Ethyl 2-(Ethoxymethylene)- 4,4,4-Trifluoro-3-Oxobutanoate

This work was financially supported by the Council for grants of the President of Russian Federation (grant no. MK-1453.2019.3)

Influência dos objetos de arquitetura verde na atratividade ecológica e turística do ambiente urbano

The development of large cities is associated with the deterioration of the environment, which pushes humanity to become aware of environmental priorities. As a result, cities have an urgent need to maximize the natural component of the urban environment. The article proposes that the design of green landscaping and architecture objects seeks to minimize the negative impact of construction on nature. The objective of this article is to evaluate the design characteristics of landscape design objects and green architecture as a means of ecological and tourist attractiveness of the urban environment. The literature review supports that there is a trend in the development of the modern urban environment thanks to the combination of urban and natural elements, which generates a new type of emotional and aesthetic impact on human beings and increases the environmental attractiveness of the urban environment for both city residents and tourists. Based on the case study method, the authors create a basic scheme for the probable implementation of the design of landscaping elements in an urban environment and the use of green architecture objects. The study of the experience of landscaping and design of green architecture objects allows us to conclude that the design of landscaping and green architecture objects is a new stage in the development of modern urban planning, based on the principles of attraction of natural components to the urban environment.El desarrollo de las grandes ciudades va asociado al deterioro del medio ambiente, lo que empuja a la humanidad a tomar conciencia de las prioridades medioambientales. Como consecuencia, las ciudades tienen la urgente necesidad de maximizar el componente natural del entorno urbano. El artículo propone que el diseño de objetos de paisajismo y arquitectura verde busque minimizar el impacto negativo de la construcción sobre la naturaleza. El objetivo de este artículo es evaluar las características de diseño de los objetos de diseño paisajístico y la arquitectura verde como medio de atractivo ecológico y turístico del entorno urbano. La revisión de la literatura apoya que existe una tendencia en el desarrollo del entorno urbano moderno gracias a la combinación de elementos urbanos y naturales, lo que genera un nuevo tipo de impacto emocional y estético en los seres humanos y aumenta el atractivo medioambiental del entorno urbano tanto para los habitantes de las ciudades como para los turistas. Basándose en el método del estudio de casos, los autores crean un esquema básico para la probable aplicación del diseño de elementos paisajísticos en un entorno urbano y el uso de objetos de arquitectura verde. El estudio de la experiencia de paisajismo y diseño de objetos de arquitectura verde permite concluir que el diseño de objetos de paisajismo y arquitectura verde es una nueva etapa en el desarrollo del urbanismo moderno, basada en los principios de atracción de componentes naturales al entorno urbano.O desenvolvimento das grandes cidades está associado à deterioração do meio ambiente, o que impele a humanidade a tomar consciência das prioridades ambientais. Como resultado, as cidades têm uma necessidade urgente de maximizar o componente natural do ambiente urbano. O artigo propõe que o projeto de objetos de paisagismo e arquitetura verde busca minimizar o impacto negativo da construção na natureza. O objetivo deste artigo é avaliar as características de projeto de objetos de paisagismo e arquitetura verde como meio de atratividade ecológica e turística do ambiente urbano. A revisão de literatura sustenta que há uma tendência no desenvolvimento do ambiente urbano moderno, graças à combinação de elementos urbanos e naturais, que gera um novo tipo de impacto emocional e estético no ser humano e aumenta a atratividade ambiental do ambiente urbano tanto para os moradores da cidade quanto para os turistas. Baseando-se no método de estudo de caso, os autores criam um esquema básico para a provável implementação do projeto de elementos de paisagismo em um ambiente urbano e o uso de objetos de arquitetura verde. O estudo da experiência de paisagismo e design de objetos de arquitetura verde permite concluir que o design de objetos de paisagismo e arquitetura verde é uma nova etapa no desenvolvimento do planejamento urbano moderno, baseado nos princípios de atração de componentes naturais para o ambiente urbano