Comparative Study of the Length-Weight Relationships of Some Fish Species along the Turkish Coasts

This study presents 738 length-weight relationships for 242 species found in Turkish seas. All length-weight relationships presented were collected from a total of 33 studies. These studies were all performed in Turkish coastal waters between 1997 and 2013. For all studies, the median of a value was calculated as 0.014 and the median of b value was calculated as 3.016

Use of oregano (Origanum onites L.) essential oil as hatching egg disinfectant

This study was carried out to determine whether oregano (Origanum onites) essential oil works as a disinfectant for hatching egg obtained from broiler breeder flock. Oregano essential oil was applied at two doses 0.55 and 0.75 ìl/cm3 and two exposure times, 3 and 6 h. The formaldehyde treated eggs were used as positive control and untreated eggs used as negative control. After chemical analysis, the main constituents of oregano essential oil were carvacrol, linalool, para-cymene and -terpinene. Thelowest microbial counts on eggs were obtained from oregano essential oil. Microbial inhibition increased with the increasing essential oil concentrations. Essential oil exposure times had no significant effects on microbial counts. Essential oil fumigation lowered middle embryonic mortality and discarded chick rate, but increased early and late embryonic mortalities compared to formaldehyde treatment. Essential oil doses significantly affected late embryonic mortality, discarded chicks rate,contamination rate, hatchability of fertile egg, body weight at 21 and 42 days, body weight gain and total feed consumption. But, early and middle embryonic mortality were not significantly affected by treatments. These results imply that oregano essential oil had great potential for hatching egg disinfectant and it could be used as natural egg disinfectant

Effects of propolis and pollen supplementations on growth performance and body components of Japanese quails (Coturnix coturnix japonica).

Abstract The present study was carried out to investigate the effects of honey bee propolis and pollen supplementation on growth performance and body components in quail (Coturnix coturnix japonica). Two experiments were conducted. In the first experiment, propolis ethanolic extract (30%, PEE) was supplemented in diets at levels of 0, 5 and 10 ml PEE kg-1 while in the second experiment, pollen was supplemented in diets at four levels (0, 5, 10 and 20 g pollen kg-1). In both experiments, chicks were fed with diet containing 240 g crude protein and 3100 kcal ME per kg diet. During the experimental period, body weight, feed consumption and feed efficiency were determined weekly. At the end of the experiments, 3 female and 3 male quail from each subgroup were killed humanely to determine body components. Experimental results showed that supplementation of PEE and pollen did not significantly affect body weight gain, feed efficiency or body components (P > 0.05). It was concluded that propolis and pollen had no effect at the levels investigated on performance and body components of quail

Dications of 3-Phenyl-indenylidene Dibenzo[ a.d ]cycloheptene: The Role of Charge in the Antiaromaticity of Cationic Systems

Dications of 9-(3-phenyl-1H-inden-1-ylidene)-5H-dibenzo[a,d]cycloheptene, 52+, were prepared by oxidation with SbF5 in SO2ClF, and their magnetic behavior was compared to dications of 9-(3-phenyl-1H-inden-1-ylidene)-9H-fluorene, 22+. The good correlation between the experimental 1H NMR shifts for the dications that were oxidized cleanly and the chemical shifts calculated by the GAIO method supported the use of the nucleus independent chemical shifts, NICS, to evaluate the antiaromaticity of the indenyl systems of 22+/52+ and their unsubstituted parent compounds, 62+ and 72+, as well as the antiaromaticity of the fluorenyl system of 22+/72+ and the aromaticity of the dibenzotropylium system of 52+/62+. Antiaromaticity was shown to be directly related to the amount of charge in the antiaromatic systems, with the antiaromatic systems more responsive to changes in the calculated NBO charge than the aromatic systems. The antiaromaticity was also shown to be directly related to the amount of delocalization in the ring system. The aromaticity of the dibenzotropylium system was much less responsive to changes in the amount of charge in the tropylium system, because the aromatic system was much more completely delocalized. Thus, antiaromatic species are more sensitive probes of delocalization than aromatic ones

Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients

Pro-coagulant and pro-inflammatory intramyocardial (micro)vasculature plays an important role in acute myocardial infarction (AMI). Currently, inhibition of serine protease dipeptidyl peptidase 4 (DPP4) receives a lot of interest as an anti-hyperglycemic therapy in type 2 diabetes patients. However, DPP4 also possesses anti-thrombotic properties and may behave as an immobilized anti-coagulant on endothelial cells. Here, we studied the expression and activity of endothelial DPP4 in human myocardial infarction in relation to a prothrombogenic endothelial phenotype. Using (immuno)histochemistry, DPP4 expression and activity were found on the endothelium of intramyocardial blood vessels in autopsied control hearts (n = 9). Within the infarction area of AMI patients (n = 73), this DPP4 expression and activity were significantly decreased, coinciding with an increase in Tissue Factor expression. In primary human umbilical vein endothelial cells (HUVECs), Western blot analysis and digital imaging fluorescence microscopy revealed that DPP4 expression was strongly decreased after metabolic inhibition, also coinciding with Tissue Factor upregulation. Interestingly, inhibition of DPP4 activity with diprotin A also enhanced the amount of Tissue Factor encountered and induced the adherence of platelets under flow conditions. Ischemia induces loss of coronary microvascular endothelial DPP4 expression and increased Tissue Factor expression in AMI as well as in vitro in HUVECs. Our data suggest that the loss of DPP4 activity affects the anti-thrombogenic nature of the endothelium

Comprehensive analysis via exome sequencing uncovers genetic etiology in autosomal recessive nonsyndromic deafness in a large multiethnic cohort

Purpose:Autosomal recessive nonsyndromic deafness (ARNSD) is characterized by a high degree of genetic heterogeneity, with reported mutations in 58 different genes. This study was designed to detect deafness-causing variants in a multiethnic cohort with ARNSD by using whole-exome sequencing (WES).Methods:After excluding mutations in the most common gene, GJB2, we performed WES in 160 multiplex families with ARNSD from Turkey, Iran, Mexico, Ecuador, and Puerto Rico to screen for mutations in all known ARNSD genes.Results:We detected ARNSD-causing variants in 90 (56) families, 54 of which had not been previously reported. Identified mutations were located in 31 known ARNSD genes. The most common genes with mutations were MYO15A (13), MYO7A (11), SLC26A4 (10), TMPRSS3 (9), TMC1 (8), ILDR1 (6), and CDH23 (4). Nine mutations were detected in multiple families with shared haplotypes, suggesting founder effects.Conclusion:We report on a large multiethnic cohort with ARNSD in which comprehensive analysis of all known ARNSD genes identifies causative DNA variants in 56 of the families. In the remaining families, WES allows us to search for causative variants in novel genes, thus improving our ability to explain the underlying etiology in more families.Genet Med 18 4, 364-371. © American College of Medical Genetics and Genomics