Circuit counts pulses and indicates time of occurrence of slow pulses

Counter includes one section which counts the first several pulses, and a second section which counts pulses from a clock between the beginning of a sampling interval and the receipt of the first pulse by the circuit. The number of clock pulses indicates receipt time of the first pulse

Counter Patent

Circuit for measuring wide range of pulse rates by utilizing high capacity counte

Screening for UBE3A gene mutations in a group of Angelman syndrome patients selected according to non-stringent clinical criteria

Abstract.: The Angelman syndrome (AS) is caused by genetic abnormalities affecting the maternal copy of chromosome region 15q12. Until recently, the molecular diagnosis of AS relied on the detection of either a deletion at 15q11-13, a paternal uniparental disomy (UPD) for chromosome 15 or imprinting mutations. A fourth class of genetic defects underlying AS was recently described and consists of mutations of the UBE3A gene. The vast majority of mutations reported so far are predicted to cause major disruptions at the protein level. It is unclear whether mutations with less drastic consequences for the gene product could lead to milder forms of AS. We report on our results obtained by screening 101 clinically diagnosed AS patients for mutations in the UBE3A gene. Non-stringent clinical criteria were purposely applied for inclusion of AS patients in this study. The mutation search was carried out by single-strand conformation polymorphism (SSCP), and SSCP/restriction fragment length polymorphism (RFLP) analyses and revealed five novel UBE3A gene mutations as well as three different polymorphisms. All five mutations were detected in patients with typical features of AS and are predicted to cause frameshifts in four cases and the substitution of a highly conserved residue in the fifth. The results we obtained add to the as yet limited number of reports concerning UBE3A gene mutations. Important aspects that emerge from the data available to date is that the four classes of genetic defects known to underlie AS do not appear to cover all cases. The genetic defect underlying approximately 10% of AS cases, including some familial cases, remains unknow

Lifetime Measurement of the 6s Level of Rubidium

We present a lifetime measurements of the 6s level of rubidium. We use a time-correlated single-photon counting technique on two different samples of rubidium atoms. A vapor cell with variable rubidium density and a sample of atoms confined and cooled in a magneto-optical trap. The 5P_{1/2} level serves as the resonant intermediate step for the two step excitation to the 6s level. We detect the decay of the 6s level through the cascade fluorescence of the 5P_{3/2} level at 780 nm. The two samples have different systematic effects, but we obtain consistent results that averaged give a lifetime of 45.57 +- 0.17 ns.Comment: 10 pages, 9 figure

Spatial separation in a thermal mixture of ultracold 174^{174}Yb and 87^{87}Rb atoms

We report on the observation of unusually strong interactions in a thermal mixture of ultracold atoms which cause a significant modification of the spatial distribution. A mixture of $^{87}$Rb and $^{174}$Yb with a temperature of a few $\mu$K is prepared in a hybrid trap consisting of a bichromatic optical potential superimposed on a magnetic trap. For suitable trap parameters and temperatures, a spatial separation of the two species is observed. We infer that the separation is driven by a large interaction strength between $^{174}$Yb and $^{87}$Rb accompanied by a large three-body recombination rate. Based on this assumption we have developed a diffusion model which reproduces our observations

Attitudes, awareness and actions of the residents of the Hinkson Creek watershed regarding water quality and environmentalism

The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.Title from title screen of research.pdf file (viewed on January 3, 2007)Vita.Includes bibliographical references.Thesis (M.S.) University of Missouri-Columbia 2007.Dissertations, Academic -- University of Missouri--Columbia -- Rural sociology.This study explored the attitudes and opinions of 4,653 homeowners in the Hinkson Creek watershed regarding water quality and environmentalism in the watershed. The Hinkson Creek flows north to south through Boone County and the city of Columbia (population 90,000) in central Missouri with a watershed that covers approximately 57,500 acres. Eight focus groups were conducted with people living in rural, exurban, suburban and urban portions of the watershed. They revealed a high level of concern for the large amount of development occurring in Boone County and how it will affect streams. A mail survey, designed from the information gained from the focus groups revealed that respondents know little about water quality in their area; whether Hinkson Creek was polluted, the largest contributors of water pollution to Hinkson Creek and they did not understand the term nonpoint source pollution. The information gained from this study can be used to develop educational programs