102 research outputs found
Memory of the Unjamming Transition during Cyclic Tiltings of a Granular Pile
Discrete numerical simulations are performed to study the evolution of the
micro-structure and the response of a granular packing during successive
loading-unloading cycles, consisting of quasi-static rotations in the gravity
field between opposite inclination angles. We show that internal variables,
e.g., stress and fabric of the pile, exhibit hysteresis during these cycles due
to the exploration of different metastable configurations. Interestingly, the
hysteretic behaviour of the pile strongly depends on the maximal inclination of
the cycles, giving evidence of the irreversible modifications of the pile state
occurring close to the unjamming transition. More specifically, we show that
for cycles with maximal inclination larger than the repose angle, the weak
contact network carries the memory of the unjamming transition. These results
demonstrate the relevance of a two-phases description -strong and weak contact
networks- for a granular system, as soon as it has approached the unjamming
transition.Comment: 13 pages, 15 figures, soumis \`{a} Phys. Rev.
Ionization yield measurement in a germanium CDMSlite detector using photo-neutron sources
Two photo-neutron sources, YBe and SbBe, have been
used to investigate the ionization yield of nuclear recoils in the CDMSlite
germanium detectors by the SuperCDMS collaboration. This work evaluates the
yield for nuclear recoil energies between 1 keV and 7 keV at a temperature of
50 mK. We use a Geant4 simulation to model the neutron spectrum assuming
a charge yield model that is a generalization of the standard Lindhard model
and consists of two energy dependent parameters. We perform a likelihood
analysis using the simulated neutron spectrum, modeled background, and
experimental data to obtain the best fit values of the yield model. The
ionization yield between recoil energies of 1 keV and 7 keV is shown to be
significantly lower than predicted by the standard Lindhard model for
germanium. There is a general lack of agreement among different experiments
using a variety of techniques studying the low-energy range of the nuclear
recoil yield, which is most critical for interpretation of direct dark matter
searches. This suggests complexity in the physical process that many direct
detection experiments use to model their primary signal detection mechanism and
highlights the need for further studies to clarify underlying systematic
effects that have not been well understood up to this point
Search for low-mass dark matter via bremsstrahlung radiation and the Migdal effect in SuperCDMS
We present a new analysis of previously published SuperCDMS data using a profile likelihood framework to search for sub-GeV dark matter (DM) particles through two inelastic scattering channels: bremsstrahlung radiation and the Migdal effect. By considering these possible inelastic scattering channels, experimental sensitivity can be extended to DM masses that are undetectable through the DM-nucleon elastic scattering channel, given the energy threshold of current experiments. We exclude DM masses down to 220ââMeV/c2 at 2.7Ă10â30ââcm2 via the bremsstrahlung channel. The Migdal channel search provides overall considerably more stringent limits and excludes DM masses down to 30ââMeV/c2 at 5.0Ă10â30ââcm2
A Search for Low-mass Dark Matter via Bremsstrahlung Radiation and the Migdal Effect in SuperCDMS
We present a new analysis of previously published of SuperCDMS data using a
profile likelihood framework to search for sub-GeV dark matter (DM) particles
through two inelastic scattering channels: bremsstrahlung radiation and the
Migdal effect. By considering these possible inelastic scattering channels,
experimental sensitivity can be extended to DM masses that are undetectable
through the DM-nucleon elastic scattering channel, given the energy threshold
of current experiments. We exclude DM masses down to at
via the bremsstrahlung channel. The Migdal
channel search provides overall considerably more stringent limits and excludes
DM masses down to at .Comment: Submitted to PR
First measurement of the nuclear-recoil ionization yield in silicon at 100 eV
We measured the nuclear--recoil ionization yield in silicon with a cryogenic
phonon-sensitive gram-scale detector. Neutrons from a mono-energetic beam
scatter off of the silicon nuclei at angles corresponding to energy depositions
from 4\,keV down to 100\,eV, the lowest energy probed so far. The results show
no sign of an ionization production threshold above 100\,eV. These results call
for further investigation of the ionization yield theory and a comprehensive
determination of the detector response function at energies below the keV
scale
Psychology and aggression
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68264/2/10.1177_002200275900300301.pd
Computational Homogenization of Architectured Materials
Architectured materials involve geometrically engineered distributions of microstructural phases at a scale comparable to the scale of the component, thus calling for new models in order to determine the effective properties of materials. The present chapter aims at providing such models, in the case of mechanical properties. As a matter of fact, one engineering challenge is to predict the effective properties of such materials; computational homogenization using finite element analysis is a powerful tool to do so. Homogenized behavior of architectured materials can thus be used in large structural computations, hence enabling the dissemination of architectured materials in the industry. Furthermore, computational homogenization is the basis for computational topology optimization which will give rise to the next generation of architectured materials. This chapter covers the computational homogenization of periodic architectured materials in elasticity and plasticity, as well as the homogenization and representativity of random architectured materials
Risk of Bowel Obstruction in Patients Undergoing Neoadjuvant Chemotherapy for High-risk Colon Cancer
Objective:
This study aimed to identify risk criteria available before the point of treatment initiation that can be used to stratify the risk of obstruction in patients undergoing neoadjuvant chemotherapy (NAC) for high-risk colon cancer.
Background:
Global implementation of NAC for colon cancer, informed by the FOxTROT trial, may increase the risk of bowel obstruction.
Methods:
A case-control study, nested within an international randomized controlled trial (FOxTROT; ClinicalTrials.gov: NCT00647530). Patients with high-risk operable colon cancer (radiologically staged T3-4 N0-2 M0) that were randomized to NAC and developed large bowel obstruction were identified. First, clinical outcomes were compared between patients receiving NAC in FOxTROT who did and did not develop obstruction. Second, obstructed patients (cases) were age-matched and sex-matched with patients who did not develop obstruction (controls) in a 1:3 ratio using random sampling. Bayesian conditional mixed-effects logistic regression modeling was used to explore clinical, radiologic, and pathologic features associated with obstruction. The absolute risk of obstruction based on the presence or absence of risk criteria was estimated for all patients receiving NAC.
Results:
Of 1053 patients randomized in FOxTROT, 699 received NAC, of whom 30 (4.3%) developed obstruction. Patients underwent care in European hospitals including 88 UK, 7 Danish, and 3 Swedish centers. There was more open surgery (65.4% vs 38.0%, P=0.01) and a higher pR1 rate in obstructed patients (12.0% vs 3.8%, P=0.004), but otherwise comparable postoperative outcomes. In the case-controlâmatched Bayesian model, 2 independent risk criteria were identified: (1) obstructing disease on endoscopy and/or being unable to pass through the tumor [adjusted odds ratio: 9.09, 95% credible interval: 2.34â39.66] and stricturing disease on radiology or endoscopy (odds ratio: 7.18, 95% CI: 1.84â32.34). Three risk groups were defined according to the presence or absence of these criteria: 63.4% (443/698) of patients were at very low risk (10%).
Conclusions:
Safe selection for NAC for colon cancer can be informed by using 2 features that are available before treatment initiation and identifying a small number of patients with a high risk of preoperative obstruction
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