Corrigendum to “Implementation of tidal turbines in MIKE 3 and Delft3D models of Pentland Firth & Orkney waters” [Ocean Coast. Manag. 147 (2017) 21–36]

© 2017 Elsevier Ltd The authors regret that a software error caused incorrect predictions for the effects of tidal turbines in Delft3D. The predictions without turbines are unaffected, as are those from the MIKE 3 model. The overall conclusions of the article remain valid. Figs. 12–15 as published are incorrect. Replacements for Figs. 12–14 are presented here. Following this correction the differences in the effects of energy extraction between the two models are much smaller. As a result the discussion of these differences in Section 6 should be disregarded, and Fig. 15 is no longer required. The authors would like to apologise for any inconvenience caused. The version of the code for adding turbines to Delft3D that is publicly available has been corrected, and anybody using this for their own work is urged to download the latest version. [Figure presented] Fig. 12: (a) 400 turbines in the Inner Sound, viewed through the MIKE Zero GUI; (b) The same 400 turbines represented as porous plates for Delft3D. Higher values of the closs parameter, shown by bluer colours, indicate plates with higher drag. [Figure presented] Fig. 13: Changes in mean current speeds over 28 days as a result of adding turbines. [Figure presented] Fig. 14: Change in mean bed stress magnitude over 28 days as a result of adding turbines, expressed as a proportion of the value without turbines

Impact of biological agents on postsurgical complications in inflammatory bowel disease: A multicentre study of Geteccu

Background: The impact of biologics on the risk of postoperative complications (PC) in inflammatory bowel disease (IBD) is still an ongoing debate. This lack of evidence is more relevant for ustekinumab and vedolizumab. Aims: To evaluate the impact of biologics on the risk of PC. Methods: A retrospective study was performed in 37 centres. Patients treated with biologics within 12 weeks before surgery were considered “exposed”. The impact of the exposure on the risk of 30-day PC and the risk of infections was assessed by logistic regression and propensity score-matched analysis. Results: A total of 1535 surgeries were performed on 1370 patients. Of them, 711 surgeries were conducted in the exposed cohort (584 anti-TNF, 58 vedolizumab and 69 ustekinumab). In the multivariate analysis, male gender (OR: 1.5; 95% CI: 1.2–2.0), urgent surgery (OR: 1.6; 95% CI: 1.2–2.2), laparotomy approach (OR: 1.5; 95% CI: 1.1–1.9) and severe anaemia (OR: 1.8; 95% CI: 1.3–2.6) had higher risk of PC, while academic hospitals had significantly lower risk. Exposure to biologics (either anti-TNF, vedolizumab or ustekinumab) did not increase the risk of PC (OR: 1.2; 95% CI: 0.97–1.58), although it could be a risk factor for postoperative infections (OR 1.5; 95% CI: 1.03–2.27). Conclusions: Preoperative administration of biologics does not seem to be a risk factor for overall PC, although it may be so for postoperative infections

Role of age and comorbidities in mortality of patients with infective endocarditis

Purpose: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. Methods: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015. Patients were stratified into three age groups:<65 years, 65 to 80 years, and = 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. Results: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 = 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients =80 years who underwent surgery were significantly lower compared with other age groups (14.3%, 65 years; 20.5%, 65-79 years; 31.3%, =80 years). In-hospital mortality was lower in the <65-year group (20.3%, <65 years;30.1%, 65-79 years;34.7%, =80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%, =80 years; p = 0.003).Independent predictors of mortality were age = 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI = 3 (HR:1.62; 95% CI:1.39–1.88), and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared, the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. Conclusion: There were no differences in the clinical presentation of IE between the groups. Age = 80 years, high comorbidity (measured by CCI), and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children

We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19 pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-alpha 2 in 10 patients: IFN-alpha 2 only in three, IFN-alpha 2 plus IFN-omega in five, and IFN-alpha 2, IFN-omega plus IFN-beta in two; IFN-omega only in nine patients). Seven children (3.8%) had Abs neutralizing at least 10 ng/ml of one IFN, whereas the other 12 (6.6%) had Abs neutralizing only 100 pg/ml. The auto-Abs neutralized both unglycosylated and glycosylated IFNs. We also detected auto-Abs neutralizing 100 pg/ml IFN-alpha 2 in 4 of 2,267 uninfected children (0.2%) and auto-Abs neutralizing IFN-omega in 45 children (2%). The odds ratios (ORs) for life-threatening COVID-19 pneumonia were, therefore, higher for auto-Abs neutralizing IFN-alpha 2 only (OR [95% CI] = 67.6 [5.7-9,196.6]) than for auto-Abs neutralizing IFN-. only (OR [95% CI] = 2.6 [1.2-5.3]). ORs were also higher for auto-Abs neutralizing high concentrations (OR [95% CI] = 12.9 [4.6-35.9]) than for those neutralizing low concentrations (OR [95% CI] = 5.5 [3.1-9.6]) of IFN-omega and/or IFN-alpha 2

Implementation of tidal turbines in MIKE 3 and Delft3D models of Pentland Firth &amp; Orkney Waters

© 2017 Elsevier Ltd As part of the Terawatt project, two regional-scale hydrodynamic models of the Pentland Firth & Orkney waters were developed using unaltered commercially-available software (MIKE 3 and Delft3D), in order to investigate the suitability of such software for predicting the effects of tidal stream energy development. Realistic scenarios for tidal energy extraction were implemented in each, and the predictions of the models with and without turbines compared. Similar predictions were made of depth-averaged current speed (spatial correlation of R2=0.95), but bed stress in one model was more than double that in the other due to the use of different values for bed resistance. The effects of energy extraction are consistent between the models at a regional scale but show considerable local differences. We conclude that these model codes are suitable for broad-scale assessment of the effects of energy extraction but that caution, and more detailed survey data, is required at fine scales

Childhood Prosocial Behavior in the School Environment

Although the study of childhood prosocial behavior is not new, there has been a recent surge in the number of studies on this topic due to increases in violence and aggression in all social environments. According to the principles of positive psychology, the promotion of prosocial behavior involves strengthening a repertoire of alternative behaviors that inhibit negative and antisocial behaviors in children while providing an adequate remedy to the expression of aggressiveness, violence, and indifference towards others. As previous studies have suggested, there are many positive effects that produce prosocial behavior throughout childhood development at the social, emotional, and cognitive levels. In this chapter, we will analyze why schools provide an appropriate context to promote helpfulness, giving and sharing, verbal comfort, positive appreciation of others, and cooperative behavior. A literature review on this subject will be compared to the results obtained following the implementation of a program directed at promoting childhood prosocial behavior in a school context. These results support the possibility of strengthening prosociality in this environment through the implementation of adequate strategies and models. Teaching children to cooperate and help others, to share and be altruistic, to accept and forgive others mistakes, and to show sympathy, empathy, and compassion should be part of any school's objectives to foster the harmonious and integral development of children.Fil: Lemos, Viviana Noemí. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Centro Interdisciplinario de Investigaciones en Psicología Matemática y Experimental "Dr. Horacio J. A. Rimoldi". Grupo Vinculado CIIPME - Entre Ríos - Centro Interdisciplinario de Investigaciones en Psicología Matemática y Experimental "Dr. Horacio J. A. Rimoldi"; ArgentinaFil: Richaud, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Centro Interdisciplinario de Investigaciones en Psicología Matemática y Experimental Dr. Horacio J. A. Rimoldi; Argentin