4,567 research outputs found
Bubble concentration on spheres for supercritical elliptic problems
We consider the supercritical Lane-Emden problem (P_\eps)\qquad
-\Delta v= |v|^{p_\eps-1} v \ \hbox{in}\ \mathcal{A} ,\quad u=0\ \hbox{on}\
\partial\mathcal{A}
where is an annulus in \rr^{2m}, and
p_\eps={(m+1)+2\over(m+1)-2}-\eps, \eps>0.
We prove the existence of positive and sign changing solutions of (P_\eps)
concentrating and blowing-up, as \eps\to0, on dimensional spheres.
Using a reduction method (see Ruf-Srikanth (2010) J. Eur. Math. Soc. and
Pacella-Srikanth (2012) arXiv:1210.0782)we transform problem (P_\eps) into a
nonhomogeneous problem in an annulus \mathcal D\subset \rr^{m+1} which can be
solved by a Ljapunov-Schmidt finite dimensional reduction
Chromosomal 16p microdeletion in Rubinstein-Taybi syndrome detected by oligonucleotide-based array comparative genomic hybridization: a case report
<p>Abstract</p> <p>Introduction</p> <p>Chromosomal aberrations of chromosome 16 are uncommon and submicroscopic deletions have rarely been reported. At present, a cytogenetic or molecular abnormality can only be detected in 55% of Rubinstein-Taybi syndrome patients, leaving the diagnosis in 45% of patients to rest on clinical features only. Interestingly, this microdeletion of 16 p13.3 was found in a young child with an unexplained syndromic condition due to an indistinct etiological diagnosis. To the best of our knowledge, no evidence of a microdeletion of 16 p13.3 with contiguous gene deletion, comprising cyclic adenosine monophosphate-response element-binding protein and tumor necrosis factor receptor-associated protein 1 genes, has been described in typical Rubinstein-Taybi syndrome.</p> <p>Case presentation</p> <p>We present the case of a three-year-old Malaysian Chinese girl with a <it>de novo </it>microdeletion on the short arm of chromosome 16, identified by oligonucleotide array-based comparative genomic hybridization. Our patient showed mild to moderate global developmental delay, facial dysmorphism, bilateral broad thumbs and great toes, a moderate size atrial septal defect, hypotonia and feeding difficulties. A routine chromosome analysis on 20 metaphase cells showed a normal 46, XX karyotype. Further investigation by high resolution array-based comparative genomic hybridization revealed a 120 kb microdeletion on chromosomal band 16 p13.3.</p> <p>Conclusion</p> <p>A mutation or abnormality in the cyclic adenosine monophosphate-response element-binding protein has previously been determined as a cause of Rubinstein-Taybi syndrome. However, microdeletion of 16 p13.3 comprising cyclic adenosine monophosphate-response element-binding protein and tumor necrosis factor receptor-associated protein 1 genes is a rare scenario in the pathogenesis of Rubinstein-Taybi syndrome. Additionally, due to insufficient coverage of the human genome by conventional techniques, clinically significant genomic imbalances may be undetected in unexplained syndromic conditions of young children. This case report demonstrates the ability of array-based comparative genomic hybridization to offer a genome-wide analysis at high resolution and provide information directly linked to the physical and genetic maps of the human genome. This will contribute to more accurate genetic counseling and provide further insight into the syndrome.</p
Lorentz angle measurements in irradiated silicon detectors between 77 K and 300 K
Future experiments are using silicon detectors in a high radiation
environment and in high magnetic fields. The radiation tolerance of silicon
improves by cooling it to temperatures below 180 K. At low temperatures the
mobility increases, which leads to larger deflections of the charge carriers by
the Lorentz force. A good knowledge of the Lorentz angle is needed for design
and operation of silicon detectors. We present measurements of the Lorentz
angle between 77 K and 300 K before and after irradiation with a primary beam
of 21 MeV protons.Comment: 13 pages, 9 figures, submitted to ICHEP2000, Osaka, Japa
Cyclotron-resonant exciton transfer between the nearly free and strongly localized radiative states of a two-dimensional hole gas in a high magnetic field
Avoided crossing of the emission lines of a nearly free positive trion and a
cyclotron replica of an exciton bound to an interface acceptor has been
observed in the magneto-photoluminescence spectra of p-doped GaAs quantum
wells. Identification of the localized state depended on the precise mapping of
the anti-crossing pattern. The underlying coupling is caused by an exciton
transfer combined with a resonant cyclotron excitation of an additional hole.
The emission spectrum of the resulting magnetically tunable coherent state
probes weak localization in the quantum well.Comment: 5 pages, 5 figure
Glasslike Arrest in Spinodal Decomposition as a Route to Colloidal Gelation
Colloid-polymer mixtures can undergo spinodal decomposition into colloid-rich
and colloid-poor regions. Gelation results when interconnected colloid-rich
regions solidify. We show that this occurs when these regions undergo a glass
transition, leading to dynamic arrest of the spinodal decomposition. The
characteristic length scale of the gel decreases with increasing quench depth,
and the nonergodicity parameter exhibits a pronounced dependence on scattering
vector. Mode coupling theory gives a good description of the dynamics, provided
we use the full static structure as input.Comment: 14 pages, 4 figures; replaced with published versio
APPENDIX to "Communicating the unknown. An interdisciplinary annotation study of uncertainty in the coronavirus pandemic"
The study 'Communicating the unknown' draws on an annotation approach to examine uncertainty in British and German newspaper articles on the coronavirus pandemic. We developed a tagset in an interdisciplinary team from corpus linguistics and sociology. After working out a gold standard on a pilot corpus, we apply the annotation to the entire corpus drawing on an âannotation-by-queryâ approach in CQPWeb, based on uncertainty constructions that have been extracted from the gold standard data. The annotated data are then evaluated and sociologically contextualised. On this basis, we study the development of uncertainty markers in the period under study and compare media discourses in Germany and the UK. We document here the CQL queries which we used to measure uncertainty in our corpora
On the symmetry of minimizers
For a large class of variational problems we prove that minimizers are
symmetric whenever they are .Comment: 17 pages, to appear in Arch. Rational Mech. Anal.; added Example 7
and some reference
Final State Interaction Effects in \u3csup\u3e3\u3c/sup\u3eHe (eâ, e\u27 p)
Asymmetries in quasi-elastic 3He(eâ, e \u27p) have been measured at a momentum transfer of 0.67 (GeV/c)2 and are compared to a calculation which takes into account relativistic kinematics in the final state and a relativistic one-body current operator. With an exact solution of the Faddeev equation for the 3He-ground state and an approximate treatment offinal state interactions in the continuum good agreement is found with the experimental data
The Ljapunov-Schmidt reduction for some critical problems
This is a survey about the application of the Ljapunov-Schmidt reduction for
some critical problems
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