Will Parent Training Reduce Abuse, Enhance Development, and Save Money? Let's Find Out

Outlines a strategy for testing the feasibility of community-developed parent training initiatives to prevent child abuse and neglect. Calls for a federal grant program to test community-wide implementation of parent training programs in stages

Racial Disproportionality, Race Disparity, and Other Race-Related Findings in Published Works Derived from the National Survey of Child and Adolescent Well-Being

Draws on articles based on the National Survey of Child and Adolescent Well-Being to examine the relationship between race/ethnicity and the child welfare agency-supervised services received, such as early intervention- and reunification-related services

Review of \u3cem\u3eClinical and Practice Issues in Adoption: Bridging the Gap Between Adoptees Placed as Infants and as Older Children.\u3c/em\u3e Victor Groza and Karen F Rosenberg (Eds.). Reviewed by Richard P. Barth, University of North Carolina, Chapel Hill.

Book review of Victor Groza and Karen E Rosenberg (Eds.), Clinical and Practice Issues in Adoption: Bridging the Gap Between Adoptees Placed as Infants and as Older Children. Westport, CT: Praeger Publishers, 1998. $55.00 (hardcover)

Review of \u3cem\u3eFamily Group Conferencing: New Directions in Community-Centered Child and Family Practice.\u3c/em\u3e Gail Buford and Joe Hudson (Eds.). Reviewed by Richard P. Barth.

Book review of Gail Buford and Joe Hudson (Eds.), Family Group Conferencing: New Directions in Community-Centered Child and Family Practice. New York: Aldine DeGruyter; $25.95, papercover, 2002

Case report: Successful treatment of recurrent chordoma and bilateral pulmonary metastases following an 11-year disease-free period

AbstractINTRODUCTIONChordomas are rare but aggressive tumors due to local recurrence and distant metastases. They originate commonly in the sphenooccipital and sacrococcygeal regions, and metastasize to the lungs, bone, skin, liver, and lymph nodes. They occur more frequently in men and people over the age of 40.PRESENTATION OF CASEA 28 year-old female presented with sacrococcygeal chordoma for which she received wide local excision and adjuvant radiation therapy. She enjoyed an unusual disease-free survival for 11 years until a routine surveillance scan of the pelvis identified local recurrence. Further work up revealed bilateral pulmonary metastases. She underwent local excision of the recurrent tumor and video-assisted thoracoscopic (VATS) wedge resection of pulmonary metastases. She also received adjuvant radiation therapy to the recurrent resection bed. Two years later, she remains free of disease and symptoms.DISCUSSIONChordomas are commonly insensitive to chemotherapy and radiation, making surgery the most successful therapeutic modality. However, there are few guidelines on the surveillance and treatment of recurrent chordoma. We report success with aggressive surgical resection of recurrence and metastasis as well as adjuvant radiation therapy.CONCLUSIONThe prolonged survival of our patient underscores the importance of (1) aggressive surgical resection of chordoma, whether primary, recurrent, or metastatic, with adjuvant radiation therapy, (2) minimization of surgical seeding of tumor, and (3) diligent cancer surveillance

Policy Recommendations for Meeting the Grand Challenge to Stop Family Violence

This brief was created forSocial Innovation for America’s Renewal, a policy conference organized by the Center for Social Development in collaboration with the American Academy of Social Work & Social Welfare, which is leading theGrand Challenges for Social Work initiative to champion social progress. The conference site includes links to speeches, presentations, and a full list of the policy briefs

The American Academy of Social Work and Social Welfare: History and Grand Challenges

Conceptualized by social work deans and actualized with the support of major social work organizations, the American Academy of Social Work and Social Welfare was established in 2009. This article describes the historical context and creation of the Academy, whose objectives include recognizing outstanding social work scholars and practitioners; informing social policy by serving as a signal scientific source of information for the social work profession and agencies seeking information; promoting the examination of social policy and the application of research to the design and development of more effective public policies, social welfare programs, and social work practice; and celebrating excellence in research, education, and practice. The Academy's 72 members have been selected using the methods of the National Academy of Science. The Academy's first substantive effort is the Grand Challenges of Social Work Initiative, designed to help transform social work science, education, and practice around visionary and achievable challenges

N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice.

The nucleus is a critical subcellular compartment for the pathogenesis of polyglutamine disorders, including Huntington's disease (HD). Recent studies suggest the first 17-amino-acid domain (N17) of mutant huntingtin (mHTT) mediates its nuclear exclusion in cultured cells. Here, we test whether N17 could be a molecular determinant of nuclear mHTT pathogenesis in vivo. BAC transgenic mice expressing mHTT lacking the N17 domain (BACHD-ΔN17) show dramatically accelerated mHTT pathology exclusively in the nucleus, which is associated with HD-like transcriptionopathy. Interestingly, BACHD-ΔN17 mice manifest more overt disease-like phenotypes than the original BACHD mice, including body weight loss, movement deficits, robust striatal neuron loss, and neuroinflammation. Mechanistically, N17 is necessary for nuclear exclusion of small mHTT fragments that are part of nuclear pathology in HD. Together, our study suggests that N17 modifies nuclear pathogenesis and disease severity in HD mice by regulating subcellular localization of known nuclear pathogenic mHTT species

Contributions of Therapist Characteristics and Stability to Intensive In-home Therapy Youth Outcomes

This study examines the influence of therapist and youth characteristics on post-discharge outcomes from intensive in-home therapy