508 research outputs found

    A tabulation of pipe length to diameter ratios as a function of Mach number and pressure ratios for compressible flow

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    Computer programs and resulting tabulations are presented of pipeline length-to-diameter ratios as a function of Mach number and pressure ratios for compressible flow. The tabulations are applicable to air, nitrogen, oxygen, and hydrogen for compressible isothermal flow with friction and compressible adiabatic flow with friction. Also included are equations for the determination of weight flow. The tabulations presented cover a wider range of Mach numbers for choked, adiabatic flow than available from commonly used engineering literature. Additional information presented, but which is not available from this literature, is unchoked, adiabatic flow over a wide range of Mach numbers, and choked and unchoked, isothermal flow for a wide range of Mach numbers

    Runtime verification of parametric properties using SMEDL

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    Parametric properties are typical properties to be checked in runtime verification (RV). As a common technique for parametric monitoring, trace slicing divides an execution trace into a set of sub traces which are checked against non-parametric base properties. An efficient trace slicing algorithm is implemented in MOP. Another RV technique, QEA further allows for nested use of universal and existential quantification over parameters. In this paper, we present a methodology for parametric monitoring using the RV framework SMEDL. Trace slicing algorithm in MOP can be expressed by execution of a set of SMEDL monitors. Moreover, the semantics of nested quantifiers is encoded by a hierarchy of monitors for aggregating verdicts of sub traces. Through case studies, we demonstrate that SMEDL provides a natural way to monitor parametric properties with more potentials for flexible deployment and optimizations

    Domain shuffling of a highly mutable ligand-binding fold drives adhesin generation across the bacterial kingdom

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    \ua9 2023 The Authors. Proteins: Structure, Function, and Bioinformatics published by Wiley Periodicals LLC. Bacterial fibrillar adhesins are specialized extracellular polypeptides that promote the attachment of bacteria to the surfaces of other cells or materials. Adhesin-mediated interactions are critical for the establishment and persistence of stable bacterial populations within diverse environmental niches and are important determinants of virulence. The fibronectin (Fn)-binding fibrillar adhesin CshA, and its paralogue CshB, play important roles in host colonization by the oral commensal and opportunistic pathogen Streptococcus gordonii. As paralogues are often catalysts for functional diversification, we have probed the early stages of structural and functional divergence in Csh proteins by determining the X-ray crystal structure of the CshB adhesive domain NR2 and characterizing its Fn-binding properties in vitro. Despite sharing a common fold, CshB_NR2 displays an ~1.7-fold reduction in Fn-binding affinity relative to CshA_NR2. This correlates with reduced electrostatic charge in the Fn-binding cleft. Complementary bioinformatic studies reveal that homologues of CshA/B_NR2 domains are widely distributed in both Gram-positive and Gram-negative bacteria, where they are found housed within functionally cryptic multi-domain polypeptides. Our findings are consistent with the classification of Csh adhesins and their relatives as members of the recently defined polymer adhesin domain (PAD) family of bacterial proteins

    Consequences of Kaizen Practices in MSMEs in the Philippines: The Case of the Manufacturing Productivity Extension Program (MPEX)

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    The Manufacturing Productivity Extension Program (MPEX) is a fully subsidized public-instigated productivity improvement program directed toward the micro, small, and medium enterprise (MSME) sector. While not advertised and packaged as a Kaizen initiative, it has all the elements of the Kaizen philosophy. Based on survey responses from 64 MPEX beneficiaries and 47 non-MPEX beneficiaries, the study showed that MPEX increased the number of product lines implying that Kaizen practice leads to product innovation among firms. Due to data and confounding issues, significant difference in productivity in terms of number of workers and sales per worker was not established. Firm asset size was implied to influence the capability to implement Kaizen. Regulatory compliance and customer demand requirements and entrepreneurial capacity are catalysts for enabling, adopting, and sustaining Kaizen implementation

    International society of sports nutrition position stand: tactical athlete nutrition

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    This position stand aims to provide an evidence-based summary of the energy and nutritional demands of tactical athletes to promote optimal health and performance while keeping in mind the unique challenges faced due to work schedules, job demands, and austere environments. After a critical analysis of the literature, the following nutritional guidelines represent the position of the International Society of Sports Nutrition (ISSN)

    Fair game: exploring the dynamics, perception and environmental impact of ‘surplus’ wild foods in England 10kya-present

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    This paper brings together zooarchaeological data from Neolithic to Post-medieval sites in England to explore the plasticity of cultural attitudes to the consumption of wild animals. It shows how, through time, game has been considered variously as ‘tabooed’ and ‘edible’, each having implications for patterns of biodiversity and wildlife management. The essential points being made are that deeper-time studies can reveal how human perceptions of ‘surplus foods’ have the potential to both create and remedy problems of environmental sustainability and food security. Perhaps more significantly, this paper argues that understanding the bio-cultural past of edible wild animal species has the potential to transform human attitudes to game in the present. This is important at a time when food security and the production of surplus are pressing national and global concerns

    The international entrepreneurial firm's social networks

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    This paper investigates theoretically the importance and impact of the international entrepreneurial firms’ (IEFs) social networks on selected firms’ strategies. We focus specifically on some core attributes of IEFs and the impact of social networks on such strategies as the choice of the foreign markets to operate and the foreign entry modes. The social networks are a major driver of the internationalization from inception and help in overcoming a variety of physical and social resource limitations as well as transactional hazards. We conclude that it is likely that both some fundamental characteristics of the IEFs and those of the foreign markets entered account for these firms reliance on their social networks
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