319 research outputs found

    Design and Performance Evaluation of Slotted Walls for Two-Dimensional Wind Tunnels

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    A procedure for designing slotted walls for two dimensional wind tunnels is is presented. The design objective is the minimization of blockage of streamline curvature or the reduction of both. The slotted wall boundary condition is derived both for flow from the tunnel into the plenum and vice versa, and the procedure for evaluating wall interference is described. A correlation of experimental data for the slotted wall boundary condition is given. Results are given for several designs and evaluations of slotted wind tunnel walls

    A potential-flow/boundary-layer method for calculating subsonic and transonic airfoil flow with trailing-edge separation

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    The development of a potential-flow/boundary-layer method for calculating subsonic and transonic turbulent flow past airfoils with trailing-edge separation is reported. A moment-of-momentum integral boundary-layer method is used which employs the law-of-the-wall/law-of-the-wake velocity profile and a two-layer eddy-viscosity model and ignores the laminar sublayer. All integrals across the boundary layer are obtained in closed form. Separation is assumed to occur when the shearing-stress velocity vanishes. A closed-form solution is derived for separated-flow regions where the shearing stress is negligible. In the potential-flow method, the exact form of the airfoil boundary condition is used, but it is applied at the chord line rather than the airfoil surface. This allows the accurate computation of flow about airfoils at large angles of attack but permits the use of body-oriented Cartesian computational grids. The governing equation for the perturbation velocity potential contains several terms in addition to the classical small-disturbance terms

    Numerical results for the diffraction of a normal shock wave by a sphere and for the subsequent transient flow

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    Finite difference method to obtain numerical results on normal shock wave diffraction by sphere and subsequent transient flo

    Analysis of transonic flow about lifting wing-body configurations

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    An analytical solution was obtained for the perturbation velocity potential for transonic flow about lifting wing-body configurations with order-one span-length ratios and small reduced-span-length ratios and equivalent-thickness-length ratios. The analysis is performed with the method of matched asymptotic expansions. The angles of attack which are considered are small but are large enough to insure that the effects of lift in the region far from the configuration are either dominant or comparable with the effects of thickness. The modification to the equivalence rule which accounts for these lift effects is determined. An analysis of transonic flow about lifting wings with large aspect ratios is also presented

    Plasmodium vivax: who cares?

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    More attention is being focused on malaria today than any time since the world's last efforts to achieve eradication over 40 years ago. The global community is now discussing strategies aimed at dramatically reducing malarial disease burden and the eventual eradication of all types of malaria, everywhere. As a consequence, Plasmodium vivax, which has long been neglected and mistakenly considered inconsequential, is now entering into the strategic debates taking place on malaria epidemiology and control, drug resistance, pathogenesis and vaccines. Thus, contrary to the past, the malaria research community is becoming more aware and concerned about the widespread spectrum of illness and death caused by up to a couple of hundred million cases of vivax malaria each year. This review brings these issues to light and provides an overview of P. vivax vaccine development, then and now. Progress had been slow, given inherent research challenges and minimal support in the past, but prospects are looking better for making headway in the next few years. P. vivax, known to invade the youngest red blood cells, the reticulocytes, presents a strong challenge towards developing a reliable long-term culture system to facilitate needed research. The P. vivax genome was published recently, and vivax researchers now need to coordinate efforts to discover new vaccine candidates, establish new vaccine approaches, capitalize on non-human primate models for testing, and investigate the unique biological features of P. vivax, including the elusive P. vivax hypnozoites. Comparative studies on both P. falciparum and P. vivax in many areas of research will be essential to eradicate malaria. And to this end, the education and training of future generations of dedicated "malariologists" to advance our knowledge, understanding and the development of new interventions against each of the malaria species infecting humans also will be essential

    Wind Tunnel Wall Interference Assessment and Correction, 1983

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    Technical information focused upon emerging wall interference assessment/correction (WIAC) techniques applicable to transonic wind tunnels with conventional and passively or partially adapted walls is given. The possibility of improving the assessment and correction of data taken in conventional transonic wind tunnels by utilizing simultaneously obtained flow field data (generally taken near the walls) appears to offer a larger, nearer-term payoff than the fully adaptive wall concept. Development of WIAC procedures continues, and aspects related to validating the concept need to be addressed. Thus, the scope of wall interference topics discussed was somewhat limited

    Low-speed aerodynamic characteristics of a 16-percent-thick variable-geometry airfoil designed for general aviation applications

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    Tests were conducted in the Langley low-turbulence pressure tunnel to determine the aerodynamic characteristics of climb, cruise, and landing configurations. These tests were conducted over a Mach number range from 0.10 to 0.35, a chord Reynolds number range from 2.0 x 1 million to 20.0 x 1 million, and an angle-of-attack range from -8 deg to 20 deg. Results show that the maximum section lift coefficients increased in the Reynolds number range from 2.0 x 1 million to 9.0 x 1 million and reached values of approximately 2.1, 1.8, and 1.5 for the landing, climb, and cruise configurations, respectively. Stall characteristics, although of the trailing-edge type, were abrupt. The section lift-drag ratio of the climb configuration with fixed transition near the leading edge was about 78 at a lift coefficient of 0.9, a Mach number of 0.15, and a Reynolds number of 4.0 x 1 million. Design lift coefficients of 0.9 and 0.4 for the climb and cruise configurations were obtained at the same angle of attack, about 6 deg, as intended. Good agreement was obtained between experimental results and the predictions of a viscous, attached-flow theoretical method

    Comparison of the human immune responses to recombinant proteins representing three distinct surface proteins of Plasmodium vivax merozoites

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    Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Departamento de Microbiologia, Imunologia e ParasitologiaUniversidade Federal do Pará Departamento de PatologiaCenters for Disease Control and Prevention Division of Parasitic DiseasesInstituto Evandro ChagasUniversidade Federal de Minas Gerais Departamento de ParasitologiaUNIFESP, EPM, Depto. de Microbiologia, Imunologia e ParasitologiaSciEL
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