Osteomielitis vertebral cervical como complicación de cirugía faríngea: a propósito de un caso

Se presenta un caso de un a enferma de 59 años, diabética, afecta de un a osteomielitis vertebral cervical por Candida Albicans. La vía de infección fué la persistencia durante varios meses de unos tutores, colocados tras la resección de un a estenosis nasofaríngea , que impactaban sobre la cara anterior de la vértebra C3. El desarrollo insidioso y la ausencia de un cuadro clínico específico fué la causa del retraso diagnóstico.A 5 9 yea r ol d woma n wit h diabete s mellitu s presente d a cervica l vertebra l osteomyelitis du e t o Candid a Albicans. Th e chroni c implantatio n o f dilatio n tube s followin g th e resectio n o f a nasopharyngea l stenosis wa s th e mod e o f infection . Th e insidiou s an d prolonge d onse t an d n o specifica l clinica l pictur e wer e t h e caus e o f dela y i n th e diagnosi

Spanish adaptation and factor structure of the Denison Organizational Culture Survey

[EN]: This article presents a Spanish adaptation of the Denison Organizational Culture Survey, a questionnaire designed to evaluate organizational culture. This survey consists of 60 items, grouped in 12 subscales, which identify 4 cultural dimensions. These dimensions have been widely studied and their influence in organizational effectiveness has been accepted. This adaptation was applied to 488 participants, and analysed with confirmatory factor analysis. Results show adequate psychometric properties, so it can be concluded that the Spanish adaptation almost completely replicates the structure of the original version in English. © 2009 Psicothema.[ES]: En este estudio se presenta la adaptación al castellano del Denison Organizational Culture Survey, una encuesta diseñada para la evaluación de la cultura organizativa. Está compuesta por 60 ítems agrupados en 12 subescalas que identifican a su vez 4 dimensiones culturales, de aceptada influencia en la efectividad organizacional. La muestra consta de 488 personas y se ha utilizado análisis factorial confirmatorio. Los resultados obtenidos señalan unas propiedades psicométricas adecuadas, por lo que cabe concluir que la adaptación española replica casi en su totalidad la estructura planteada en la versión original.Este trabajo se enmarca en un proyecto de investigación aprobado por el Ministerio de Educación y Ciencia titulado: «Influencia de la cultura organizativa y el flujo de conocimiento sobre el rendimiento científico de los grupos de I+D tecnológicos. Aplicación en la Universidad Politécnica de Valencia» (SEJ2005_08603).Peer Reviewe

Adaptación al castellano y estructura factorial del Denison

6 pages, 4 tables[ES]En este estudio se presenta la adaptación al castellano del Denison Organizational Culture Survey, una encuesta diseñada para la evaluación de la cultura organizativa. Está compuesta por 60 ítems agrupados en 12 subescalas que identifican a su vez 4 dimensiones culturales, de aceptada influencia en la efectividad organizacional. La muestra consta de 488 personas y se ha utilizado análisis factorial confirmatorio. Los resultados obtenidos señalan unas propiedades psicométricas adecuadas, por lo que cabe concluir que la adaptación española replica casi en su totalidad la estructura planteada en la versión original.[EN]Spanish adaptation and factor structure of the Denison Organizational Culture Survey. This article presents a Spanish adaptation of the Denison Organizational Culture Survey, a questionnaire designed to evaluate organizational culture. This survey consists of 60 items, grouped in 12 subscales, which identify 4 cultural dimensions. These dimensions have been widely studied and their influence in organizational effectiveness has been accepted. This adaptation was applied to 488 participants, and analysed with confirmatory factor analysis. Results show adequate psychometric properties, so it can be concluded that the Spanish adaptation almost completely replicates the structure of the original version in English.Este trabajo se enmarca en un proyecto de investigación aprobado por el Ministerio de Educación y Ciencia titulado: «Influencia de la cultura organizativa y el flujo de conocimiento sobre el rendimiento científico de los grupos de I+D tecnológicos. Aplicación en la Universidad Politécnica de Valencia» (SEJ2005_08603).Peer reviewe

An Ontological-based Knowledge-Representation Formalism for Case-Based Argumentation

The final publication is available at Springer via http://dx.doi.org/10.1007/s10796-014-9524-3[EN] In open multi-agent systems, agents can enter or leave the system, interact, form societies, and have dependency relations with each other. In these systems, when agents have to collaborate or coordinate their activities to achieve their objectives, their different interests and preferences can come into conflict. Argumentation is a powerful technique to harmonise these conflicts. However, in many situations the social context of agents determines the way in which agents can argue to reach agreements. In this paper, we advance research in the computational representation of argumentation frameworks by proposing a new ontologicalbased, knowledge-representation formalism for the design of open MAS in which the participating software agents are able to manage and exchange arguments with each other taking into account the agents’ social context. This formalism is the core of a case-based argumentation framework for agent societies. In addition, we present an example of the performance of the formalism in a real domain that manages the requests received by the technicians of a call centre.This work is supported by the Spanish government grants [CONSOLIDER-INGENIO 2010 CSD2007-00022, TIN2011-27652-C03-01, and TIN2012-36586-C03-01] and by the GVA project [PROMETEO II/2013/019].Heras Barberá, SM.; Botti, V.; Julian Inglada, VJ. (2014). An Ontological-based Knowledge-Representation Formalism for Case-Based Argumentation. Information Systems Frontiers. 1-20. https://doi.org/10.1007/s10796-014-9524-3S120Amgoud, L. (2005). An argumentation-based model for reasoning about coalition structures. In 2nd international workshop on argumentation in multi-agent systems, argmas-05(pp. 1–12). Springer.Amgoud, L., Dimopolous, Y., Moraitis, P. (2007). A unified and general framework for argumentation-based negotiation. In 6th international joint conference on autonomous agents and multiagent systems, AAMAS-07. IFAAMAS.Atkinson, K., & Bench-Capon, T. (2008). Abstract argumentation scheme frameworks. In Proceedings of the 13th international conference on artificial intelligence: methodology, systems and applications, AIMSA-08, lecture notes in artificial intelligence (Vol. 5253, pp. 220–234). Springer.Aulinas, M., Tolchinsky, P., Turon, C., Poch, M., Cortés, U. (2012). Argumentation-based framework for industrial wastewater discharges management. Engineering Applications of Artificial Intelligence, 25(2), 317–325.Bench-Capon, T., & Atkinson, K. (2009). Argumentation in artificial intelligence, chap. abstract argumentation and values (pp. 45–64). Springer.Bench-Capon, T., & Sartor, G. (2003). A model of legal reasoning with cases incorporating theories and values. Artificial Intelligence, 150(1-2), 97–143.Bulling, N., Dix, J., Chesñevar, C.I. (2008). Modelling coalitions: ATL + argumentation. In Proceedings of the 7th international joint conference on autonomous agents and multiagent systems, AAMAS-08 (Vol. 2, pp. 681–688). ACM Press.Chesñevar, C., McGinnis, J., Modgil, S., Rahwan, I., Reed, C., Simari, G., South, M., Vreeswijk, G., Willmott, S. (2006). Towards an argument interchange format. The Knowledge Engineering Review, 21(4), 293–316.Diaz-Agudo, B., & Gonzalez-Calero, P.A. (2007). Ontologies: A handbook of principles, concepts and applications in information systems, integrated series in information systems, chap. an ontological approach to develop knowledge intensive cbr systems (Vol. 14, pp. 173–214). Springer.Dung, P.M. (1995). On the acceptability of arguments and its fundamental role in nonmonotonic reasoning, logic programming, and N -person games. Artificial Intelligence, 77, 321–357.Ferber, J., Gutknecht, O., Michel, F. (2004). From agents to organizations: An organizational view of multi-agent systems. In Agent-oriented software engineering VI, LNCS (Vol. 2935, pp. 214–230.) Springer-Verlag.Hadidi, N., Dimopolous, Y., Moraitis, P. (2010). Argumentative alternating offers. In 9th international conference on autonomous agents and multiagent systems, AAMAS-10 (pp. 441–448). IFAAMAS.Heras, S., Atkinson, K., Botti, V., Grasso, F., Julián, V., McBurney, P. (2010). How argumentation can enhance dialogues in social networks. In Proceedings of the 3rd international conference on computational models of argument, COMMA-10, frontiers in artificial intelligence and applications (Vol. 216, pp. 267–274). IOS Press.Heras, S., Botti, V., Julián, V. (2011). On a computational argumentation framework for agent societies. In Argumentation in multi-agent systems (pp. 123–140). Springer.Heras, S., Botti, V., Julián, V. (2012). Argument-based agreements in agent societies. Neurocomputing, 75(1), 156–162.Heras, S., Jordán, J., Botti, V., Julián, V. (2013). Argue to agree: A case-based argumentation approach. International Journal of Approximate Reasoning, 54(1), 82–108.Jordán, J., Heras, S., Julián, V. (2011). A customer support application using argumentation in multi-agent systems. In 14th international conference on information fusion (FUSION-11) (pp. 772– 778).Karunatillake, N.C. (2006). Argumentation-based negotiation in a social context. Ph.D. thesis, School of Electronics and Computer Science, University of Southampton, UK.Karunatillake, N.C., Jennings, N.R., Rahwan, I., McBurney, P. (2009). Dialogue games that agents play within a society. Artificial Intelligence, 173(9-10), 935–981.Kraus, S., Sycara, K., Evenchik, A. (1998). Reaching agreements through argumentation: a logical model and implementation. Artificial Intelligence, 104, 1–69.López de Mántaras, R., McSherry, D., Bridge, D., Leake, D., Smyth, B., Craw, S., Faltings, B., Maher, M.L., Cox, M., Forbus, K., Keane, M., Watson, I. (2006). Retrieval, reuse, revision, and retention in CBR. The Knowledge Engineering Review, 20(3), 215–240.Luck, M., & McBurney, P. (2008). Computing as interaction: Agent and agreement technologies. In IEEE international conference on distributed human-machine systems. IEEE Press.Oliva, E., McBurney, P., Omicini, A. (2008). Co-argumentation artifact for agent societies. In 5th international workshop on argumentation in multi-agent systems, Argmas-08 (pp. 31–46). Springer.Ontañón, S., & Plaza, E. (2007). Learning and joint deliberation through argumentation in multi-agent systems. In 7th international conference on agents and multi-agent systems, AAMAS-07. ACM Press.Ontañón, S., & Plaza, E. (2009). Argumentation-based information exchange in prediction markets. In Argumentation in multi-agent systems, LNAI (vol. 5384, pp. 181–196). Springer.Parsons, S., Sierra, C., Jennings, N.R. (1998). Agents that reason and negotiate by arguing. Journal of Logic and Computation, 8(3), 261–292.Prakken, H. (2010). An abstract framework for argumentation with structured arguments. Argument and Computation, 1, 93–124.Prakken, H., Reed, C., Walton, D. (2005). Dialogues about the burden of proof. In Proceedings of the 10th international conference on artificial intelligence and law, ICAIL-05 (pp. 115–124). ACM Press.Sierra, C., Botti, V., Ossowski, S. (2011). Agreement computing. KI - Künstliche Intelligenz 10.1007/s13218-010-0070-y .Soh, L.K., & Tsatsoulis, C. (2005). A real-time negotiation model and a multi-agent sensor network implementation. Autonomous Agents and Multi-Agent Systems, 11(3), 215–271.Walton, D., Reed, C., Macagno, F. (2008). Argumentation schemes. Cambridge University Press.Wardeh, M., Bench-Capon, T., Coenen, F.P. (2008). PISA - pooling information from several agents: Multiplayer argumentation from experience. In Proceedings of the 28th SGAI international conference on artificial intelligence, AI-2008 (pp. 133–146). Springer.Wardeh, M., Bench-Capon, T., Coenen, F.P. (2009). PADUA: A protocol for argumentation dialogue using association rules. AI and Law, 17(3), 183–215.Wardeh, M., Coenen, F., Bench-Capon, T. (2010). Arguing in groups. In 3rd international conference on computational models of argument, COMMA-10 (pp. 475–486). IOS Press.Willmott, S., Vreeswijk, G., Chesñevar, C., South, M., McGinnis, J., Modgil, S., Rahwan, I., Reed, C., Simari, G. (2006). Towards an argument interchange format for multi-agent systems. In 3rd international workshop on argumentation in multi-agent systems, ArgMAS-06 (pp. 17–34). Springer.Wyner, A., & Schneider, J. (2012). Arguing from a point of view. In Proceedings of the first international conference on agreement technologies

Anticitrullinated peptide antibodies (ACPA) in the serum of heavy smokers without arthritis - a differential role of associated pulmonary disease?

2 páginas, 1 tabla.-- Póster presentado al 5º European Workshop on Immune-Mediated Inflammatory Diseases celebrado en Sitges (Barcelona) del 1 al 3 de Diciembre de 2010.An increased risk of RA has been described in smokers, but only in ACPA-positive RA patients. The frequency of ACPA in serum of heavy smokers is not known.Peer reviewe

Multi-domain case-based module for customer support

[EN] Technology management centres provide technological and customer support services for private or public organisations. Commonly, these centres offer support by using a helpdesk software that facilitates the work of their operators. In this paper, a CBR module that acts as a solution recommender for customer support environments is presented. The CBR module is flexible and multi-domain, in order to be easily integrable with any existing helpdesk software in the company. (c) 2008 Elsevier Ltd. All rights reserved.This work was partially supported by CONSOLIDER-INGENIO 2010 under grant CSD2007-00022 and by the Spanish government and FEDER funds under PROFIT FIT-340001-2004-11, CICYT TIN2005-03395 and TIN2006-14630-C0301 projectsHeras Barberá, SM.; Garcia Pardo Gimenez De Los Galanes, JA.; Ramos-Garijo Font De Mora, R.; Palomares Chust, A.; Botti, V.; Rebollo Pedruelo, M.; Julian Inglada, VJ. (2009). Multi-domain case-based module for customer support. Expert Systems with Applications. 36(3):6866-6873. https://doi.org/10.1016/j.eswa.2008.08.003S6866687336

A meta-analysis of state-of-the-art electoral prediction from Twitter data

Electoral prediction from Twitter data is an appealing research topic. It seems relatively straightforward and the prevailing view is overly optimistic. This is problematic because while simple approaches are assumed to be good enough, core problems are not addressed. Thus, this paper aims to (1) provide a balanced and critical review of the state of the art; (2) cast light on the presume predictive power of Twitter data; and (3) depict a roadmap to push forward the field. Hence, a scheme to characterize Twitter prediction methods is proposed. It covers every aspect from data collection to performance evaluation, through data processing and vote inference. Using that scheme, prior research is analyzed and organized to explain the main approaches taken up to date but also their weaknesses. This is the first meta-analysis of the whole body of research regarding electoral prediction from Twitter data. It reveals that its presumed predictive power regarding electoral prediction has been rather exaggerated: although social media may provide a glimpse on electoral outcomes current research does not provide strong evidence to support it can replace traditional polls. Finally, future lines of research along with a set of requirements they must fulfill are provided.Comment: 19 pages, 3 table

Is it possible to diagnose the therapeutic adherence of patients with COPD in clinical practice? A cohort study

<p>Abstract</p> <p>Background</p> <p>Therapeutic adherence of patients with chronic obstructive pulmonary disease (COPD) is poor. It is therefore necessary to determine the magnitude of non-adherence to develop strategies to correct this behaviour. The purpose of this study was to analyse the diagnostic validity of indirect adherence methods.</p> <p>Methods</p> <p>Sample: 195 COPD patients undergoing scheduled inhaled treatment attending 5 Primary Care Centres of Malaga, Spain. Variables: Sociodemographic profile, illness data, spirometry, quality of life (St. George Respiratory Questionnaire: SGRQ), and inhaled medication counting (count of dose/pill or electronic monitoring) were collected. The patient's knowledge of COPD (Batalla test:BT),their attitude towards treatment (Morisky-Green test: MGT) and their self-reported therapeutic adherence (Haynes-Sackett test: HST) were used as methods of evaluating adherence. The follow-up consisted four visits over one year (the recruitment visit: V0; and after 1 month:V1; 6 months:V2; and 1 year:V3).</p> <p>Results</p> <p>The mean age was 69.59 (95% CI, 68.29-70.89) years old and 93.8% were male. Other findings included: 85.4% had a low educational level, 23.6% were smokers, 71.5% mild-moderate COPD stage with a FEV1 = 56.86 (SD = 18.85); exacerbations per year = 1.41(95% CI, 1-1.8). The total SGRQ score was 44.96 (95% CI, 42.46-47.46), showing a mild self-perceived impairment in health. The prevalence of adherence (dose/pill count) was 68.1% (95% CI, 60.9-75.3) at V1, 80% (95% CI, 73-87) at V2 and 84% (95% CI, 77.9) at V3. The MGT showed a specificity of 67.34% at V1, 76.19% at V2 and 69.62% at V3. The sensitivity was 53.33% at V1, 66.66% at V2 and 33.33% at V3.The BT showed a specificity of 55.1% at V1, 70.23% at V2 and 67.09% at V3. The sensitivity was 68.88% at V1, 71.43% at V2 and 46.66% at V3. Considering both tests together, the specificity was 86.73% at V1, 94.04% at V2 and 92.49% at V3 and the sensitivity was 37.77% at V1, 47.62% at V2 and 13.3% at V3.</p> <p>Conclusions</p> <p>The prevalence of treatment adherence changes over time. Indirect methods (dose/pill count and self-reported) can be useful to detect non-adherence in COPD patients. The combination of MGT and BT is the best approach to test self-reported adherence.</p

Carbapenem-resistant Citrobacter spp. isolated in Spain from 2013 to 2015 produced a variety of carbapenemases including VIM-1, OXA-48, KPC-2, NDM-1 and VIM-2

Objectives: There is little information about carbapenemase-producing (CP) Citrobacter spp.We studied the molecular epidemiology and microbiological features of CP Citrobacter spp. isolates collected in Spain (2013-15). Methods: In total, 119 isolates suspected of being CP by the EUCAST screening cut-off values were analysed. Carbapenemases and ESBLs were characterized using PCR and sequencing. The genetic relationship among Citrobacter freundii isolates was studied by PFGE. Results: Of the 119 isolates, 63 (52.9%) produced carbapenemases, of which 37 (58.7%) produced VIM-1, 20 (31.7%) produced OXA-48, 12 (19%) produced KPC-2, 2 (3.2%) produced NDM-1 and 1 (1.6%) produced VIM- 2; 9 C. freundii isolates co-produced VIM-1 plus OXA-48. Fourteen isolates (22.2%) also carried ESBLs: 8 CTX-M-9 plus SHV-12, 2 CTX-M-9, 2 SHV-12 and 2 CTX-M-15. Fifty-seven isolates (90.5%) were C. freundii, 4 (6.3%) were Citrobacter koseri, 1 (1.6%) was Citrobacter amalonaticus and 1 (1.6%) was Citrobacter braakii. By EUCAST breakpoints, eight (12.7%) of the CP isolates were susceptible to the four carbapenems tested. In the 53 CP C. freundii analysed by PFGE, a total of 44 different band patterns were observed. Four PFGE clusters were identified: cluster 1 included eight isolates co-producing VIM-1 and OXA-48; blaVIM-1 was carried in a class 1 integron (intI-blaVIM-1 - aacA4-dfrB1-aadA1-catB2-qacE¿1/sul1) and blaOXA-48 was carried in a Tn1999.2 transposon. Conclusions: We observed the clonal and polyclonal spread of CP Citrobacter spp. across several Spanish geographical areas. Four species of Citrobacter spp. produced up to five carbapenemase types, including coproduction of VIM-1 plus OXA-48. Some CP Citrobacter spp. isolates were susceptible to the four carbapenems tested, a finding with potential clinical implications

Evolution of innovation policy in Emilia-Romagna and Valencia: Similar reality, similar results?

This is an author's accepted manuscript of an article published in: “European Planning Studies"; Volume 22, Issue 11, 2014; copyright Taylor & Francis; available online at: http://dx.doi.org/10.1080/09654313.2013.831398[EN] This paper examines the evolution of regional innovation policy in Emilia-Romagna and Valencia, two regions with similar economic features that implemented close innovation policies in the 1970s and 1980s. We investigate whether their similarities have led to parallel targets, policy tools and governance developments. We show that innovation policy in both regions suffered from the effects of privatization, budget constraints and changes to manufacturing during the 1990s and we highlight the consequences. Although Emilia-Romagna experienced deeper changes to its innovation policy, privatizations and/or the replacement of public funds promoted commercial approaches and induced market failures in both regions. The worst effects of these policies were the implementation of less-risky innovation projects, the shift towards extraregional projects and markets, and the favouring of large firms.López Estornell, M.; Barberá Tomás, JD.; Garcia Reche, A.; Mas Verdú, F. (2013). Evolution of innovation policy in Emilia-Romagna and Valencia: Similar reality, similar results?. European Planning Studies. 22(11):2287-2304. doi:10.1080/09654313.2013.831398S22872304221