Pensando la historia más allá de la nación : La historiografía de América Latina y la perspectiva transnacional

“Pensando história fora da nação: a historiografia da América Latina e o viés transnacional” fue pronunciada en el “X° Encontro Internacional da Associação Nacioanal de Pesquisadores e Professores de História das Américas” realizado en São Paulo en julio de 2012 y publicada posteriormente en Revista Eletrônica da ANPHLAC, 14, enero-junio 2013, 13-31.Facultad de Humanidades y Ciencias de la Educació

Deja que entre la luz del sol: archivos de gobierno e inseguridades nacionales

Barbara Weinstein (Universidad de Nueva York) es presidenta de la Asociación Americana de Historiadores. Publicado en: Barbara Weinstein, "Let the Sunshine In: Government Records and National Insecurities", Perspectives, 45:4, April 2007Universidad Nacional de La Plata (UNLP) - Facultad de Humanidades y Ciencias de la Educació

Deja que entre la luz del sol: archivos de gobierno e inseguridades nacionales

Barbara Weinstein (Universidad de Nueva York) es presidenta de la Asociación Americana de Historiadores. Publicado en: Barbara Weinstein, "Let the Sunshine In: Government Records and National Insecurities", Perspectives, 45:4, April 2007Universidad Nacional de La Plata (UNLP) - Facultad de Humanidades y Ciencias de la Educació

Promoting hearing and cognitive health in audiologic rehabilitation for the well-being of older adults

Objective: With our aging population, an increasing number of older adults with hearing loss have cognitive decline. Hearing care practitioners have an important role in supporting healthy aging and should be knowledgeable about cognitive decline and associated management strategies to maximize successful hearing intervention. Methods: A review of current research and expert opinion. Results: This article outlines the association between hearing loss and cognitive decline/dementia, hypothesized mechanisms underlying this, and considers current research into the effects of hearing intervention on cognitive decline. Cognition into old age, cognitive impairment, dementia, and how to recognize cognitive decline that is not part of normal aging are described. Screening of older asymptomatic adults for cognitive decline and practical suggestions for the delivery of person-centered hearing care are discussed. Holistic management goals, personhood, and person-centered care in hearing care management are considered for older adults with normal cognitive aging through to dementia. A case study illustrates important skills and potential management methods. Prevention strategies for managing hearing and cognitive health and function through to older age, and strategies to maximize successful hearing aid use are provided. Conclusion: This article provides evidence-based recommendations for hearing care professionals supporting older clients to maximize well-being through the cognitive trajectory

La abolición de la esclavitud en Hispanoamérica y Brasil : Nuevos aportes y debates historiográficos [Recurso electrónico]

Los esfuerzos de los esclavos en pos de la abolición en Ecuador / Camilla Townsend. El final de la esclavitud y el final del imperio: la emancipación de los esclavos en Cuba y Puerto Rico / Christopher Schmidt-Nowara. La abolición de la trata de esclavos en Brasil en 1850: historiografía, acción esclava y el arte de estadista / Jeffrey Needell. La abolición en el Brasil: Movimientos sociales y políticos en el sudeste cafetalero / María Helena Pereira Toledo Machado. La decadencia del plantador progresista y el auge del agente subalterno: Cambios en las narrativas de la emancipación de los esclavos en el Brasil / Barbara Weinstei

Assessment of Fractionated Exhaled Nitric Oxide as a Biomarker for the Treatment of Eosinophilic Esophagitis

Diagnosis of eosinophilic esophagitis (EoE) and determination of response to therapy is based on histological assessment of the esophagus, which requires upper endoscopy. In children, in whom a dietary approach is commonly used, multiple endoscopies are needed, because foods are eliminated and then gradually reintroduced. Ideally, noninvasive methods could supplement or replace upper endoscopy to facilitate management. Fractionated exhaled nitric oxide (FeNO) has been proposed as a useful measure for monitoring disease activity in studies of patients with eosinophil-predominant asthma and in other atopic disorders. Thus, we evaluated whether FeNO levels could be a useful biomarker to assess the response to therapy in EoE patients. This study was designed to determine whether there is a change in FeNO levels during treatment with topical corticosteroids and whether changes correlated with clinical response. This was a prospective, multicenter study that enrolled nonasthmatic patients with established EoE. FeNO levels and symptom scores were measured at baseline, biweekly during 6-week swallowed fluticasone treatment, and 4 weeks posttreatment. Twelve patients completed the trial. We found a statistically significant difference between median pre- and posttreatment FeNO levels [20.3 ppb (16.0–29.0 ppb) vs 17.6 ppb (11.7–27.3 ppb), p=0.009]. However, neither the pretreatment FeNO level, a change of FeNO level after 2 weeks of treatment, nor the FeNO level at the end of treatment confidently predicted a clinical or histological response. Although our findings suggest nitric oxide possibly has a physiological role in EoE, our observations do not support a role of FeNo determination for management of EoE

Genetic Risk Score Predicts Late-Life Cognitive Impairment

Introduction. A family history of Alzheimer's disease is a significant risk factor for its onset, but the genetic risk associated with possessing multiple risk alleles is still poorly understood. Methods. In a sample of 95 older adults (Mean age = 75.1, 64.2% female), we constructed a genetic risk score based on the accumulation of risk alleles in BDNF, COMT, and APOE. A neuropsychological evaluation and consensus determined cognitive status (44 nonimpaired, 51 impaired). Logistic regression was performed to determine whether the genetic risk score predicted cognitive impairment above and beyond that associated with each gene. Results. An increased genetic risk score was associated with a nearly 4-fold increased risk of cognitive impairment (OR = 3.824, P = .013) when including the individual gene polymorphisms as covariates in the model. Discussion. A risk score combining multiple genetic influences may be more useful in predicting late-life cognitive impairment than individual polymorphisms