Current Mirror Circuits with Improved Performance

Current mirrors are core structures for almost all analog mode circuits and are integral part of a signal processing elements like op amps. The performance of analog structures largely depends on their characteristics. In this paper we present some of the current mirror circuits and analyze their performances, so that one can choose a suitable current mirror for a particular application

Wallace Tree Multiplier Designs: A Performance Comparison Review

Multiplication process is often used in digital signal processing systems, microprocessors designs, communication systems, and other application specific integrated circuits. Multipliers are complex units and play an important role in deciding the overall area, speed and power consumption of digital designs. This paper presents a comparison review of various Wallace tree multiplier designs in terms of parameters like latency, complexity and power consumption. Keywords: Booth Recoding Algorithm, Carry Look Ahead Adder, Carry Select Adder, Compressors, Ripple Carry Adder, Sklansky Adder, Wallace Tree Multipliers

Rare Occurrence of Single Rooted Mandibular Left First and Third Permanent Mandibular Molar: A Case Report

For any practicing clinician, successful endodontic therapy is highly dependent upon complete knowledge of the anatomy and the variations present in the human dentition. There are variances in anatomical configurations in teeth seen across the globe and might needs specialized treatment techniques. The tendency of Asians to show a C- shaped canal morphology has been documented in the literature, however, in contrast to those findings, we report a unique and a rare case of  left mandibular first and third molar

Recent Advances in Optogenetic Retinal Prostheses

Optogenetics has emerged as a revolutionary technology that enables circuit-specific restoration of neuronal function with millisecond temporal resolution. Restoring vision is one of the most promising and forefront applications of optogenetics. This chapter discusses essential components, mechanisms, present challenges, and future prospects of optogenetic retinal prostheses. The theoretical framework and analysis of optogenetic excitation of retinal ganglion neurons are also presented, which are useful in developing a better understanding and guidance for future experiments. It shows that the newly discovered ChRmine opsin provides control at light powers that are two orders of magnitude smaller than that required with experimentally studied opsins that include ChR2, ReaChR, and ChrimsonR, while maintaining single-spike temporal resolution, in retinal ganglion neurons

REVIEW ON USING BIOMETRIC SIGNALS IN RANDOM NUMBER GENERATORS.

Random numbers play an important role in digital security and are used in encryption, public key cryptography to ensure the safe and unchanged transmission. Random number generators are required to generate these random numbers, but true randomness is difficult to achieve and requires a true random source to generate the number which cannot be predicted from the knowledge of previous inputs. This paper discusses about incorporating biometrics and cryptography for stronger security and to generate random numbers with true randomness. Biometric systems are used to uniquely identify individuals in the security but uses a sophisticated procedure. Biometric signals are non-deterministic processes that are unpredictable and good source of randomness. This paper reviews the feasibility of using biometric signals in Random Number Generator (RNG) discuss whether biometric signals such as heartbeats, vascular patterns, iris scans and human Galvanic Skin Response (GSR) can be used in nearby future to generate reliable Random numbers. This paper will also review the work done towards generating random numbers using these biometric signals and the result of them, verified with statistical test suites such as NIST

Efficacy of short term versus long term antibiotic therapy in preventing deep wound infections in elective orthopaedic surgeries

Background: Comparison of the efficacy of short term (up to 48 hours) versus long term (five days) antibiotic therapy in preventing deep wound infections in elective orthopaedic surgeries.Methods: Two hundred patients of all ages and both sexes were divided into two groups of 100 patients. One group received long term antibiotic treatment consisting of 2 days intra-venous cefoperazone sulbactam 1.5 gm twice daily and intra-venous amikacin 500 mg twice daily followed by 3 days of oral amoxicillin clavulunate 625 mg thrice daily. Other group received short term antibiotic of 2 days intra-venous cefoperazone sulbactam 1.5 gm twice daily and intra-venous amikacin 500 mg twice daily. Comparison of SSI was done with age, sex, BMI, pre-operative haemoglobin, TLC, duration of surgery in both the groups.Results: In group I and group II respectively, average duration of surgery in procedures involving implants was 65.02±27.41 and 59.47±20.27 minutes and non implant related procedures was 53.66±23.97 and 53.74±22.40 minutes. Overall incidence of SSI in Group I and Group II was 14% and 10% respectively. Mean infection in the present study was 12%.Conclusions: It was concluded that in clean orthopaedic elective surgeries short term antibiotics regimen is as effective as long term antibiotics regimen. Continuing antibiotics for more than two days is associated with drug related complications like allergic reactions and gastrointestinal upset, adverse interactions in other drugs, development of resistant organisms and it adds to overall cost of treatment

Long-term trends of direct nitrous oxide emission from fuel combustion in South Asia

An increasing concentration of nitrous oxide (N2O) in the global atmosphere can perturb the ecological balance, affecting the climate and human life. South Asia, one of the world's most populous regions, is a hotspot for N2O emission. Although agriculture traditionally dominated the region, economic activities are rapidly shifting towards industry and energy services. These activites may become the largest emitters of N2O in future. Yet, few attempts have been made to estimate long-term direct N2O emission from fuel combustion for the different energy-consuming sectors in the South Asian region. Therefore, the present study developed a comprehensive sectoral N2O emission inventory for South Asian countries for the time period of 1990–2017, with projections till 2041. It revealed that the average N2O emission from fuel combustion in the South Asia region is about 40.96 Gg yr−1 with a possible uncertainty of ±12 Gg yr−1, showing an increase of more than 100% from 1990 to 2017. Although India is the major contributor, with an average of 34 Gg yr−1 of N2O emissions, in terms of growth, small countries like Bhutan and Maldives are dominating other South Asian countries. Sector-wise, the residential sector contributed a maximum emission of 14.52 Gg yr−1 of N2O but this is projected to reduce by more than 50% by 2041. This is because of the successful promotion of cleaner fuels like liquefied petroleum gas over more polluting fuelwood. Power generation contributed 9.43 Gg yr−1of N2O emissions, exhibiting a maximum growth of 395%, followed by road transport (289%) and industry (231%). Future N2O emissions from transport, power and industry are projected to rise by 2.8, 3.3, and 23.9 times their 2017 estimates, respectively, due to the incapability of current policies to combat rising fossil fuel consumption. Mitigation options, such as replacing diesel and compressed natural gas vehicles with electricity-driven vehicles, can decelerate N2O emissions to 45% by 2041 for road transport. A 41% reduction is possible by displacing coal with renewables in the power and industry sectors. Overall, the South Asian contribution to global N2O emissions has enlarged from 2.7% in 1990 to 5.7% in 2007–2016, meaning there is an urgent need for N2O emission mitigation in the region

Deep phenotyping and genomic data from a nationally representative study on dementia in India

The Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) is a nationally representative in-depth study of cognitive aging and dementia. We present a publicly available dataset of harmonized cognitive measures of 4,096 adults 60 years of age and older in India, collected across 18 states and union territories. Blood samples were obtained to carry out whole blood and serum-based assays. Results are included in a venous blood specimen datafile that can be linked to the Harmonized LASI-DAD dataset. A global screening array of 960 LASI-DAD respondents is also publicly available for download, in addition to neuroimaging data on 137 LASI-DAD participants. Altogether, these datasets provide comprehensive information on older adults in India that allow researchers to further understand risk factors associated with cognitive impairment and dementia.Peer reviewe